Supporting women farmers in a changing climate: five policy lessons

Policies, institutions and services to help farmers develop new approaches to deal with climate change will need to produce results for women farmers as well as men. This brief provides five policy lessons to support this process, based on evidence from research in low- and middle- income countries and offers guidelines for crafting gender-responsive climate policies at global and national levels. This research was presented in March 2015 at a seminar in Paris on ‘Closing the gender gap in farming under climate change’, co-organized by the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS), the International Social Science Council (ISSC) and Future Earth

Etude rétrospective sur la sortie précoce de prématuré d'un service de néonatologie en 2000

PARIS13-BU Serge Lebovici (930082101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

MENINGITES BACTERIENNES NEONATALES (PLACE DES FLUOROQUINOLONES)

PARIS7-Villemin (751102101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Culture-Negative Neonatal Meningitis and Endocarditis Caused by Streptococcus agalactiae

We describe a case of culture-negative meningitis and endocarditis caused by Streptococcus agalactiae in a 27-day-old boy. S. agalactiae was detected in cerebrospinal fluid and serum by broad-spectrum PCR amplification

Comparison of T Cell Functional Changes during Childhood with the Ontogeny of CDw29 and CD45RA Expression on CD4+ T Cells

International audienc

Treatment Failure of Nosocomial Pertussis Infection in a Very-Low-Birth-Weight Neonate

We describe a case of nosocomial maternal transmission of Bordetella pertussis to a very-low-birth-weight (VLBW) neonate in whom treatment was unsuccessful. This case underscores the need for rapid and sensitive PCR diagnosis in VLBW neonates and in parents with clinical signs of pertussis and suggests that standard treatment may not be appropriate for VLBW neonates

Escherichia coli bacteraemia in children: age and portal of entry are the main predictors of severity

International audienceBackground: Escherichia coli bacteraemia is a major cause of severe sepsis in children. Little is known about predictors of severity.Methods: We analysed 84 children ≤18-year-old with E. coli bacteraemia from the prospective COLIBAFI study performed in 2005-2007. Bacteraemia’s severity was defined as occurrence of death or transfer to intensive care unit. Studied characteristics included age, gender, birth weight, history of prematurity, immunodepression, nosocomial infection, portal of entry, phylogenetic group and subgroup belonging, O-type, virulence gene content and antimicrobial susceptibility. We compared bacterial characteristics in urinary- vs. digestive-source bacteraemia, in children ≤3 vs. >3-month-old, and in children vs. adults. We also searched for risk factors of severity.Results: Median age was 2.4 months, 57% males. Most frequent portals of entry were urinary and digestive tracts. Most isolates belonged to B2 phylogroup. Strains in children ≤3-month-old exhibited more virulence genes, especially neuC and fyuA/irp2, and were less resistant to antibiotics than in children >3-month-old. Comparing community-acquired urinary-source bacteraemia between children and adults, we found that bacteraemia were less severe in children, whose strains exhibited a specific virulence gene repertoire and had a higher resistance score than in adults. Seventeen children (20.2%) had a severe bacteraemia and 8 died. Non-urinary portal of entry and age ≤3-month-old were the only risk factors associated with severity.Conclusions: E. coli strains responsible for bacteraemia exhibit specific characteristics according to age of children. However, host characteristics and portal of entry are the main determinants of severity of E. coli bacteraemia in children, as observed in adults

Detection and Identification by PCR of a Highly Virulent Phylogenetic Subgroup among Extraintestinal Pathogenic Escherichia coli B2 Strains

Closely related Escherichia coli B2 strains O1:K1, O2:K1, O18:K1, and O45:K1 constitute a major subgroup causing extraintestinal infections. A DNA pathoarray analysis was used to develop a PCR specific for this subgroup that was included in the multiplex phylogenetic-grouping PCR method. Our PCR may serve to identify this virulent subgroup among different ecological niches