Primary children’s understanding and relationship with cartoon characters : a multimodal praxis-based research experience

This paper presents the research outcomes of a two-year research venture conducted by Attard (2019) which links theory to classroom-based praxis. In brief, the first part of the paper presents a sound theoretical grounding based on international literature about primary school children’s understanding and relationship with cartoon characters. Later, based on the critical theoretical literature review presented in the first part, the paper links the outcomes to two levels of praxis. Initially, it presents how nine / ten-year-old children attending Maltese primary schools understand and relate to cartoon characters based on their everyday cartoon watching experiences. Then, based on an original multimodal framework (Cremona, 2017), as a main conclusion, a set of practical multimodal suggestions are proposed. These suggestions are intended to be used by educators, parents or guardians with primary school children.peer-reviewe

Perceived ability and actual recognition accuracy for unfamiliar and famous faces

In forensic person recognition tasks, mistakes in the identification of unfamiliar faces occur frequently. This study explored whether these errors might arise because observers are poor at judging their ability to recognize unfamiliar faces, and also whether they might conflate the recognition of familiar and unfamiliar faces. Across two experiments, we found that observers could predict their ability to recognize famous but not unfamiliar faces. Moreover, observers seemed to partially conflate these abilities by adjusting ability judgements for famous faces after a test of unfamiliar face recognition (Experiment 1) and vice versa (Experiment 2). These findings suggest that observers have limited insight into their ability to identify unfamiliar faces. These experiments also show that judgements of recognition abilities are malleable and can generalize across different face categories

Origin and complete breed standard of Maltese black breed

This review is a first attempt to give a comprehensive historical account on the evolution of the Maltese Black chicken breed. The initiative consolidates available information to propose hypothesis on the origins of the breed, and to develop a comprehensive breed standard in conformity with the format of the American Breed Standard. The Maltese Black was established in 1950 as a rustic, dual purpose breed capable of producing adequate egg and chicken for consumption. In the 1960's, it was replaced with commercially available stock, marginalising the breed and restricting its existence to small dispersed populations. An initial attempt to have an in-situ conservation of the Maltese Black started in 1998 with a small flock of about 400 chickens that were later relocated to the Agricultural Research and Development Centre in Malta with the intention of maintaining a nucleus flock as a measure for a long term ex-situ conservation strategy. A recent survey highlights that the present population has drifted significantly away from standards first published in 1950. In efforts to consolidate the breed standard definition of the Maltese Black, the breed standards of related Mediterranean breeds, as confirmed by molecular markers, were consulted to translate and address the missing gaps in the previous breed standards. The updated breed standard presented will act as the bench mark against which all future breeding and selection programs are compared.peer-reviewe

Patient attendance at a primary health care centre in Malta : a cross-sectional observational study

Introduction The aim of the study was to describe the reason for consultation of patients attending the General Practitioner (GP) service at a major local health centre and also to get a clinical profile of the patients making use of such health service. This study is based in the publiclyfunded primary health system in Malta and focuses on Mosta Health Centre. Methodology This was a cross-sectional observational study carried out in January 2017. Only the patients seen in the GP clinics were included. All six authors are practicing GPs. All the patients that the authors encountered in the GP clinics were included in the study. The fact that all authors work in different shifts and days allowed for a broad and random inclusion of patients. Patients attending out-ofhours and in weekends were also included. A pilot oneweek period of data collection was carried out. Thereafter, all six authors had an Excel spreadsheet uploaded on the work computer system in the GP consulting rooms, so that patient data was inputted in real-time at the end of each consultation. Data was inputted in Excel 2010 and analysed using the Statistical Package for the Social Sciences (SPSS) 22. Results A total of 820 patients were included in the study. 51.8% of patients were females, whilst 74.8% of patients were born in Malta. 50.2% of patients raised more than one issue during a single consultation, whilst the most common co-morbidity noted was hypertension. The most common reasons for consultation were related to the respiratory and musculoskeletal systems. Various significant associations were observed, most importantly being between the time of attendance and number of issues brought up during a consultation; between being born in Malta and number of issues brought up during a consultation; and between age and number of issues brought up during a single consultation. Conclusion This study involved 820 patients attending Mosta Health Centre over a one-month period during winter 2017. During a single episode of care (visit), Maltese nationals consult for a greater number of issues. In addition, they have a greater number of co-morbidities than non-Maltese nationals. People attending between 08.00 and 17.00 hours tend to present with a greater number of issues for management. Suggestions for service development have been put forward in the discussion. Ideally, such studies should be conducted independently in different health centres given the notable differences in the catchment areas, and during different months of the year.peer-reviewe

Pygmy blue whale movement, distribution and important areas in the Eastern Indian Ocean

This study was conducted as part of AIMS’ North West Shoals to Shore Research Program (NWSSRP) and was supported by Santos as part of the company’s commitment to better understand Western Australia’s marine environment. Hydrophone pressure data from Ocean Bottom Seismometers (OBS) were provided by the CANPASS project, jointly funded by the National Natural Science Foundation of China (NSFC grants 91955210, 41625016), and the China Academy of Science (CAS program GJHZ1776). Instruments were provided by the Australian National instrument pool ANSIR (http://ansir.org.au/). ANSIR, OBS data was also made data available from the Geoscience Australia and Shell. Data was sourced from Australia’s Integrated Marine Observing System (IMOS).Pygmy blue whales in the South-east Indian Ocean migrate from the southern coast of Australia to Indonesia, with a significant part of their migration route passing through areas subject to oil and gas production. This study aimed at improving our understanding of the spatial extent of the distribution, migration and foraging areas, to better inform impact assessment of anthropogenic activities in these regions. Using a combination of passive acoustic monitoring of the NW Australian coast (46 instruments from 2006 to 2019) and satellite telemetry data (22 tag deployments from 2009 to 2021) we quantified the pygmy blue whale distribution and important areas during their northern and southern migration. We show extensive use of slope habitat off Western Australia and only minimal use of shelf habitat, compared to southern Australia where use of the continental shelf and shelf break predominates. In addition, movement behaviour estimated by a state-space model on satellite tag data showed that in general pygmy blue whales off Western Australia were mostly engaged in migration, interspersed with mostly relatively short periods (median = 28hours, range = 2 – 1080hours) of low move persistence (slow movement with high turning angles), which is indicative of foraging. Using the spatial overlap of time and number of whales in area analysis of the satellite tracking data (top 50% of grid cells) with foraging movement behaviour, we quantified the spatial extent of pygmy blue whale high use areas for foraging and migration. We compared these areas to the previously described areas of importance to foraging and migrating whales (Biologically Important Areas; BIAs). In some cases these had good agreement with the most important areas we calculated from our data, but others had only low (5%) to moderate (13%) overlap. Month was the most important variable predicting the number of pygmy blue whale units and number of singers (acting as indices of pygmy blue whale density). Whale density was highest in the southern part of the NW Australian coast and whales were present there between April-June, and November-December, a pattern also confirmed by the satellite tracking data. Available data indicated pygmy blue whales spent up to 124 days in Indonesian waters (34% of annual cycle). Since this area may also be the calving ground for this population, inter-jurisdictional management is necessary to ensure their full protection.Publisher PDFPeer reviewe

Green Solvent Selection for Emulsifiable Concentrate Agrochemical Formulations

Emulsifiable concentrates are a common form of agrochemical formulation in which a high quantity of active ingredient is typically dissolved in an aromatic hydrocarbon solvent. There are considerable health and environmental hazards associated with the solvents in emulsifiable concentrates, and finding alternatives was deemed worthy of investigation. Using a combination of in silico modeling and experimental testing, a number of alternative safer solvents have been tested for the agrochemicals pendimethalin, prochloraz, and pyraclostrobin. Cyclohexanone, diethyl carbonate, ethyl acetate, and dihydrolevoglucosenone (Cyrene) were observed to be effective solvents

Ecological drivers of eggshell wettability in birds

Complex and at times extreme environments have pushed many bird species to develop unique eggshell surface properties to protect the embryo from external threats. Because microbes are usually transmitted into eggs by moisture, some species have evolved hydrophobic shell surfaces that resist water absorption, while also regulating heat loss and the exchange of gases. Here, we investigate the relationship between wettability of eggshells from 441 bird species and their life-history traits. We measured the initial contact angle between sessile water droplets and the shell surface, and how far the droplet spread. Using phylogenetic comparative methods, we show that body mass, annual temperature and eggshell maculation primarily explained variance in water contact angle across eggshells. Species nesting in warm climates were more likely to exhibit highly hydrophobic eggshells than those nesting in cold climates, potentially to reduce microbial colonisation. In non-passerines, immaculate eggs were found to have more hydrophobic surfaces than maculate eggshells. Droplets spread more quickly on eggshells incubated in open nests compared to domed nests, likely to decrease heat transfer from the egg. Here, we identify clear adaptations of eggshell wettability across a diverse range of nesting environments, driven by the need to retain heat and prevent microbial adhesion

Valorization of spruce needle waste via supercritical extraction of waxes and facile isolation of nonacosan-10-ol

Supercritical carbon dioxide was utilized as a sustainable alternative to solvent extraction of waxes from the waste needles of two spruce species, namely Norwegian and Sitka spruce. These extracts were rich in nonacosan-10-ol, an organic compound with hydrophobic properties that lends its use in the preparation of superhydrophobic coatings. The highest crude yields were 1.7% w/w of needles obtained at 400 bar and 60 °C, while nonacosan-10-ol was selectively extracted at 200 bar and 60 °C (8070 ± 91.1 μg/g of needles). Purification of nonacosan-10-ol from the wax extracts was conducted using a simple rapid green recrystallization technique. This yielded a recovery of 44.6% ± 2% and 48.4% ± 2% of the total nonacosan-10-ol from the original crude Sitka (3600 μg/g of needles) and Norwegian wax (1920 μg/g of needles) respectively. Application of nonacosan-10-ol to a filter paper led to the formation of highly hydrophobic surfaces, with preliminary contact angles of up to 149°. This sustainable production method may develop opportunities to valorize forestry waste within a holistic biorefinery

A novel prostate cancer subtyping classifier based on luminal and basal phenotypes

Background: Prostate cancer (PCa) is a clinically heterogeneous disease. The creation of an expression-based subtyping model based on prostate-specific biological processes was sought. Methods: Unsupervised machine learning of gene expression profiles from prospectively collected primary prostate tumors (training, n = 32,000; evaluation, n = 68,547) was used to create a prostate subtyping classifier (PSC) based on basal versus luminal cell expression patterns and other gene signatures relevant to PCa biology. Subtype molecular pathways and clinical characteristics were explored in five other clinical cohorts. Results: Clustering derived four subtypes: luminal differentiated (LD), luminal proliferating (LP), basal immune (BI), and basal neuroendocrine (BN). LP and LD tumors both had higher androgen receptor activity. LP tumors also had a higher expression of cell proliferation genes, MYC activity, and characteristics of homologous recombination deficiency. BI tumors possessed significant interferon γactivity and immune infiltration on immunohistochemistry. BN tumors were characterized by lower androgen receptor activity expression, lower immune infiltration, and enrichment with neuroendocrine expression patterns. Patients with LD tumors had less aggressive tumor characteristics and the longest time to metastasis after surgery. Only patients with BI tumors derived benefit from radiotherapy after surgery in terms of time to metastasis (hazard ratio [HR], 0.09; 95% CI, 0.01–0.71; n = 855). In a phase 3 trial that randomized patients with metastatic PCa to androgen deprivation with or without docetaxel (n = 108), only patients with LP tumors derived survival benefit from docetaxel (HR, 0.21; 95% CI, 0.09–0.51). Conclusions: With the use of expression profiles from over 100,000 tumors, a PSC was developed that identified four subtypes with distinct biological and clinical features. Plain language summary: Prostate cancer can behave in an indolent or aggressive manner and vary in how it responds to certain treatments. To differentiate prostate cancer on the basis of biological features, we developed a novel RNA signature by using data from over 100,000 prostate tumors—the largest data set of its kind. This signature can inform patients and physicians on tumor aggressiveness and susceptibilities to treatments to help personalize cancer management

Integrated biorefinery approach to valorise Saccharina latissima biomass : Combined sustainable processing to produce biologically active fucoxanthin, mannitol, fucoidans and alginates

The feasibility of European seaweed farming depends on the valorisation of algal biomass harvested. In the present work we have combined sequential extraction processes from Saccharina latissima to produce a range of products, focusing on the extraction of fucoxanthin using supercritical CO2 followed by different valorisation routes. We optimised the conditions the for extraction of fucoxanthin (40 MPa, temperature has little impact on extraction) and the extracts obtained were tested on cancer cell cultures to determine the antiproliferative effects of this pigment. We established that the supercritical CO2 extracts have an antiproliferative effect similar to that of commercial fucoxanthin (concentrations 0.1–0.4 mg/mL) and showed that the active compound in the extracts is fucoxanthin. In order to integrate this process with a holistic valorisation of the algal biomass, we explored the extraction of mannitol using a microwave-assisted protocol (4.15 wt % yield). We also evaluated the potential extraction of fucoidans and alginates from the solids remaining after supercritical CO2 extraction (67.27 to 69.38 % of alginates). A life cycle analysis of the supercritical CO2 extraction proposed shows that the drying process of algal biomass and the energy used to compress the CO2 are the elements with the highest environmental impact (over 90% of CO2 eq/g of extract) in this the process, indicating routes for reducing the environmental footprint. Combining supercritical CO2 extraction and microwave-assisted extraction methods would enable European seaweed producers to obtain multiple marketable products from algal biomass