Dress Behind Bars: Prison Clothing as Criminality

Research for this sole-authored book was undertaken during AHRC-funded Research Leave (2007). It represents Ash’s expertise as a dress historian and interest in the history and current organisation of prisons, which evolved from her teaching experience in Holloway women’s prison and Wakefield top security men’s prison in the 1970s. Crossing the disciplines of dress history, social history and film studies, this is the first book to examine the history of prisoners' clothing. Focusing on UK, American and European prison clothing, this history analyses waves of reform, sandwiched between regimes of punishing clothing restraints. Prison clothing, as Ash demonstrates, raises issues of regional, colonial, post-colonial, gender, fashion and class variations, contested by collective, political and individual tactics devised by inmates to survive and subvert cultures of punishment. This book is based on research into penal history, dress history in relation to uniforms and corporeal identity, criminological debates, oral histories, and 19th- and 20th-century prison art and literature. Material from correspondence and interviews with prisoners, prison reform groups, those who work as designers in prisons, and curators of prison photography and dress informed the study. To demonstrate the value of the clothes themselves to researchers, Ash also wrote an article for the Journal of Design History on ‘The prison uniforms collection at the galleries of Justice Museum, Nottingham, UK’ (2011). The book was reviewed by journals including Journal of Design History (2011), British Journal of Criminology (2011), Textile History (2011), Australian and New Zealand Journal of Criminology (2010) and Crime Media Culture (2010). Related talks included ‘Prison clothing as political resistance’ at NCAD Dublin (2010). BBC Radio 4 made the book the focus of an episode of Thinking Allowed (2009), and Ash was interviewed about women prisoners' attitudes to uniforms and prison clothing for ABC Radio National (Australian Broadcasting Corporation, 2013)

The Untruthful Source: Writings, official and reform documentation 1900 - 1930

Ash’s article, ‘The untruthful source: Prisoner’s writings, official and reform documentation, 1900–1930’, published following her 2009 book on prison dress, questions how myths arose about the history of prisoners’ clothing in Britain in the first half of the 20th century. Ash shows that, although there was little critical writing about prisoners’ clothing in this period, the inmates’ own writing and archival documentation provide us with the means to achieve a new understanding of the political encounters played out in courtrooms. Ash’s research material included interwar Home Office circulars that announced the abolition of ‘broad arrow’ prison uniforms in 1920 and responses of prison governors that reveal their continuance after this date. Other key reform documents consulted by the author included those of Sidney and Beatrice Webb, Fenner Brockway’s 1922 Prison System Enquiry Committee Report, later published as English Prisons Under Local Government, which proposed radical prison reforms including the abolition of prison dress as criminal stigmatisation, and inmate testimonials of the continuance of the broad arrow uniform. The article demonstrates the difficulty for design historians investigating prison dress in establishing the truth about specific penal reform dates and practices on the basis of official government documents alone. Ash argues that the publications of penal reformers and the prison writings of inmates at the time also need to be read, in order to establish the clothing prisoners actually wore in confinement. Ash first presented this research as a paper to the 2009 Design History Society annual conference hosted by the theorising Visual Art and Design (tVAD) Research Group, School of Creative Arts, University of Hertfordshire. It was then selected to be peer reviewed and published in the University of Hertfordshire Working Papers on Design web-based journal

HIV and Vertebral Fractures: a Systematic Review and Metanalysis.

The survival of HIV-infected patients has increased with the advent of antiretroviral therapy with the emergence of new comorbidities. Vertebral fracture is a manifestation of reduced bone strength and osteoporosis. This study aims to assess the frequency of spine fractures in HIV-positive men and women aged over 18 years. We performed a systematic review of randomized controlled trials, cohort studies, cross-sectional studies, and case-control studies. Studies that evaluated morphometric and/or clinical vertebral fracture were included. In total 488 studies were found, of which 53 had their full texts evaluated. A total of 85,411 HIV positive individuals were identified in 26 studies. The meta-analysis of the prevalence of vertebral fractures included 12 studies with 10,593 subjects. The prevalence was 11.1% [95% confidence interval (95% CI) 4.5%, 25.0%, I2 98.2% p < 0.00001]. When we evaluated independently studies of clinical vertebral fracture and morphometric vertebral fracture, the prevalence was 3.9% (95% CI 0.9, 15.8, I2 96.4% p < 0.00001) and 20.2% (95% CI 15.7%, 25.6%, I2 69.9% p = 0.003) respectively. HIV-infected individuals had an odds ratio of vertebral fractures of 2.3 (95% CI 1.37, 3.85, I2 98.2% p < 0.00001) when compared with HIV-uninfected patients (n = 9 studies). In conclusion, HIV-positive subjects had a higher risk of vertebral fractures when compared with HIV-negative subjects

Development of an amplicon-based sequencing approach in response to the global emergence of mpox

The 2022 multicountry mpox outbreak concurrent with the ongoing Coronavirus Disease 2019 (COVID-19) pandemic further highlighted the need for genomic surveillance and rapid pathogen whole-genome sequencing. While metagenomic sequencing approaches have been used to sequence many of the early mpox infections, these methods are resource intensive and require samples with high viral DNA concentrations. Given the atypical clinical presentation of cases associated with the outbreak and uncertainty regarding viral load across both the course of infection and anatomical body sites, there was an urgent need for a more sensitive and broadly applicable sequencing approach. Highly multiplexed amplicon-based sequencing (PrimalSeq) was initially developed for sequencing of Zika virus, and later adapted as the main sequencing approach for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Here, we used PrimalScheme to develop a primer scheme for human monkeypox virus that can be used with many sequencing and bioinformatics pipelines implemented in public health laboratories during the COVID-19 pandemic. We sequenced clinical specimens that tested presumptively positive for human monkeypox virus with amplicon-based and metagenomic sequencing approaches. We found notably higher genome coverage across the virus genome, with minimal amplicon drop-outs, in using the amplicon-based sequencing approach, particularly in higher PCR cycle threshold (Ct) (lower DNA titer) samples. Further testing demonstrated that Ct value correlated with the number of sequencing reads and influenced the percent genome coverage. To maximize genome coverage when resources are limited, we recommend selecting samples with a PCR Ct below 31 Ct and generating 1 million sequencing reads per sample. To support national and international public health genomic surveillance efforts, we sent out primer pool aliquots to 10 laboratories across the United States, United Kingdom, Brazil, and Portugal. These public health laboratories successfully implemented the human monkeypox virus primer scheme in various amplicon sequencing workflows and with different sample types across a range of Ct values. Thus, we show that amplicon-based sequencing can provide a rapidly deployable, cost-effective, and flexible approach to pathogen whole-genome sequencing in response to newly emerging pathogens. Importantly, through the implementation of our primer scheme into existing SARS-CoV-2 workflows and across a range of sample types and sequencing platforms, we further demonstrate the potential of this approach for rapid outbreak response.This publication was made possible by CTSA Grant Number UL1 TR001863 from the National Center for Advancing Translational Science (NCATS), a component of the National Institutes of Health (NIH) awarded to CBFV. INSA was partially funded by the HERA project (Grant/ 2021/PHF/23776) supported by the European Commission through the European Centre for Disease Control (to VB).info:eu-repo/semantics/publishedVersio

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

The Prison Uniforms Collection at the Galleries of Justice Museum, Nottingham, UK

An examination of prison clothing in the Galleries of Justice Galleries archive makes visible the prison reforms in the 1970s and 1990s when respectively women and later male inmates’ prison uniforms were abolished in British prisons. The collection of prison uniforms and everyday dress of inmates is critically investigated as an invaluable resource for charting the sensorial materiality of historical change in prison clothing provision in Britain in the late 20th century