Hubungan Usia dan Lama Kerja dengan keluhan Nyeri Punggung Bawah (NPB) pada Pengemudi ojek online (X) di Palembang

Latar Belakang: Nyeri Punggung Bawah (NPB) merupakan gangguan pada bagian otot rangka yang diakibatkan karena otot menerima beban statis secara berulang yang menyebabkan keluhan pada sendi, ligament serta tendon yang paling sering terjadi dalam aktivitas kerja.Tujuan:penelitian ini untuk mengetahui hubungan usia dan lama kerja dengan keluhan nyeri punggung bawah pada pengemudi gojek di Palembang.Metode:Penelitian ini merupakan penelitian kuantitatif yang bersifat observasional analitik dengan rancangan pendekatan cross sectional, berlokasi di Kota Palembang dengan besar sampel 150 orang (purposive sampling). Data yang dikumpulkan berasal dari kuisioner. Hasil: Terdapat hubungan yang signifikan antara usia dan lama kerja dengan nyeri punggung bawah pada pengemudi gojek di Palembang. Variabel yang berhubungan dengan NPB yaitu usia p=0,000 (p<0,05), lama kerja p=0,023 (p<0,05), dan pendidikan p=0,003 (p<0,05). Kesimpulan: Terdapat hubungan yang signifikan antara usia dan lama kerja dengan nyeri punggung bawah pada pengemudi gojek di Palembang. Hasil penelitian didapatkan pengemudi gojek paling banyak berusia 36-45 tahun dengan lama kerja paling banyak ≥ 8 jam dan mengalami nyeri punggung paling banyak pada 1 minggu terakhir

Potential Antioxidant Kombucha Fortified with Balinese Salak Juice (Salacca zalacca Var Amboinensis) From Karangasem District

Salak (Salacca zalacca Var. Amboinensis) is widely spread in Indonesia. Processing salak using fermentation method can provide added value and extend the shelf life. Fermented salak product combined with kombucha from balck tea is expected to increase the product’s ability to inhibit free radicals and provide healthful effects for health, especially the digestive process. This research endeavors to assess the capacity and antioxidant activity (IC50) from the product. The data that has been obtained was analyzed statistically using a completely randomized two-factor design. The first factor involves the ratio of salak extract to black tea, featuring three levels 80:20 ; 70:30 ; 60:40. The second factor encompasesses varying fermentation duration with four levels 4,8,12, and 16 days fermentation. The experiment was replicated three times. The result is that the comparison of salak extract with black tea had an antioxidant capacity between 101,37-479,30 GAE/100g. The result for antioxidant activity (IC 50) between 97,77-179,61 ppm

Virtual Laboratory Based Guided Inquiry: Viscosity Exsperiments

This study aims to develop a virtual laboratory (Vir-lab) based guided inquiry on viscosity experiments and know the students' perceptions of the products developed. This study was a research and development using 4D model that consists of four stage: define, design, develop, disseminate. The participants were two material experts, two media experts, and 43 students. Data collection used expert assessment sheet and student response questionnaire. The data were analyzed descriptively. The result of this study was a Vir-lab which was packaged in e-book form with 3D effects. The activities in the Vir-lab are designed based on the syntax of guided inquiry. The Vir-lab contains goals, problem formulations, theories, hypotheses, tutorial videos, virtual experiments, experimental data, data analysis, results, and conclusions. The results of the material expert obtained a score of 45 with a very good category and media experts obtained a score of 66 with a very good category, and the results of the students' perception test obtained a score of 60.65 with a very good category. The conclusion of this study shows that the Vir-lab is valid and suitable for use as a medium for learning physics

Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo

BACKGROUND: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagon-like peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated. METHODS: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallel-group, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy. RESULTS: Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69% are men and 75% are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m(2), and duration of T2DM was 9.3 ± 8.2 years. The qualifying ACS was a myocardial infarction in 83% and unstable angina in 17%. The study will continue until the positive adjudication of the protocol-specified number of primary CV events. CONCLUSION: ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk