Control de estabilidad de un robot por medio de señales ultrasónicas

Actualmente son diversos los métodos utilizados para la medición de una inclinación de un cuerpo respecto a una referencia o un marco fijo, pero el problema radica en los costos que estos acarrean, siendo este un factor limitante para el desarrollo científico cuando se dispone de bajos recursos económicos. En Este punto es en donde se hace relevante la investigación y el desarrollo en materia de tecnología llevado a cavo, en este articulo, ya que la finalidad del presente proyecto, consiste en proporcionarle estabilidad a un robot autónomo de un solo eje, para lo cual se hace necesario, la implementación de un sistema de control de inclinación. El sistema de detección de inclinación desarrollado, está basado en el ultrasonido como herramienta principal de medición de distancia entre dos puntos equidistantes del eje central de la plataforma robótica, la cual es inestable por naturaleza. Mediante este nuevo método, se ha logrado establecer magnitudes de inclinación del orden de fracciones de grados, ya que los transductores piezoeléctricos en conjunto con la electrónica implementada, brinda gran precisión en las medidas realizadas

ESTUDIO TÉCNICO-FINANCIERO PARA LA VIABILIDAD DE UN TRATAMIENTO DE FRACTURAMIENTO HIDRÁULICO EN CAMPO ESCUELA COLORADO

RESUMEN El objetivo del trabajo es presentar la evaluación de factibilidad de realizar un trabajo de fracturamiento hidráulico en pozos de Campo Colorado. Para tal fin se consideró que para que un tratamiento de fracturamiento sea exitoso se deben cumplir dos criterios: que la fractura sea técnicamente ejecutable y económicamente viable. Mediante un modelo de producción se seleccionaron los pozos que presentarían mayor potencial al disminuir el daño en cara de pozo. Posteriormente se realizó la evaluación técnica mediante la caracterización geomecánica de la formación la cual permitió establecer: presión de poro, propiedades mecánicas y esfuerzos. Se seleccionaron los intervalos a intervenir con ayuda del modelo petrofísico. A estos intervalos se le evaluó la factibilidad de generar una fractura hidráulica mediante la determinación del tipo de falla inicial de la roca, presencia de barreras de contención de altura, gradiente de fractura y contraste de propiedades mecánicas. Mediante la metodología del diseño unificado de fractura se diseñó la geometría óptima de fractura la cual maximizaría la productividad el pozo. Este potencial incremental de diseño fue utilizado para evaluar la viabilidad económica del tratamiento de fracturamiento el cual permite establecer si la inversión inicial y el costo operativo del tratamiento son recuperables durante el tiempo del tratamiento. Palabras clave: Fracturamiento hidráulico, Diseño unificado de fractura, Modelo geomecánico, Propiedades mecánicas, Contraste de esfuerzos, Criterio de falla.  STUDY OF VIABILITY TECHNICAL- FINANCIAL FOR A HYDRAULIC FRACTURING TREATMENT IN COLORADO FIELD  ABSTRACT The aim of this paper is to present the evaluation of feasibility of hydraulic fracturing job in Colorado Field wells. For this reason, it was considered for a hydraulic fracturing treatment in Colorado’s wells to be successful you must fulfill two criteria: the fracture has to be technically enforceable and economically feasible. With a production model there were selected the Wells that presented greater potential to reduce the damage in the wellbore. Later the technical evaluation was made by geomechanical characterization of lithological column which allowed setting: pore pressure, mechanical properties and stress. Intervals were selected to intervene using the petrophysical model. Within these intervals it was evaluated the feasibility of generating a hydraulic fracture by determining the type of initial failure of the rock, presence of high containment barriers of height, fracture gradient and contrast of mechanical properties. According to the Unified Fracture Design methodology it was designed the optimum fracture geometry which maximizes the well productivity. This potential incremental design was used to evaluate the economic feasibility of fracturing which allowed to establish whether the initial investment and operating cost of treatment were recovered during the treatment time. Keywords: Hydraulic fracturing, unified fracture design, geomechanical model, mechanical properties, stress differences, faulting criterion

Control stability of robot by means ultrasonic signals

Currently there are various methods used for measuring an inclination of a body with respect to a reference or a fixed frame, but the problem is that these carry costs, this being a limiting factor for the development of science when you have low income economic. At this point it becomes relevant where the research and development in technology led to dig in this article, since the purpose of this project is to provide stability to an autonomous robot one axis, for which becomes necessary, the implementation of a tilt control system. The tilt detection system developed is based on ultrasound as the primary tool for measuring distance between two points equidistant from the central axis of the robotic platform, which is inherently unstable. With this new method has been established tilt magnitudes of the order of fractions of degrees, as the piezoelectric transducers in conjunction with electronics implemented, provides greater precision in the measurementsActualmente son diversos los métodos utilizados para la medición de una inclinación de un cuerpo respecto a una referencia o un marco fijo, pero el problema radica en los costos que estos acarrean, siendo este un factor limitante para el desarrollo científico cuando se dispone de bajos recursos económicos. En Este punto es en donde se hace relevante la investigación y el desarrollo en materia de tecnología llevado a cavo, en este articulo, ya que la finalidad del presente proyecto, consiste en proporcionarle estabilidad a un robot autónomo de un solo eje, para lo cual se hace necesario, la implementación de un sistema de control de inclinación. El sistema de detección de inclinación desarrollado, está basado en el ultrasonido como herramienta principal de medición de distancia entre dos puntos equidistantes del eje central de la plataforma robótica, la cual es inestable por naturaleza. Mediante este nuevo método, se ha logrado establecer magnitudes de inclinación del orden de fracciones de grados, ya que los transductores piezoeléctricos en conjunto con la electrónica implementada, brinda gran precisión en las medidas realizadas

Control de estabilidad de un robot por medio de señales ultrasónicas

Actualmente son diversos los métodos utilizados para la medición de una inclinación de un cuerpo respecto a una referencia o un marco fijo, pero el problema radica en los costos que estos acarrean, siendo este un factor limitante para el desarrollo científico cuando se dispone de bajos recursos económicos. En Este punto es en donde se hace relevante la investigación y el desarrollo en materia de tecnología llevado a cavo, en este articulo, ya que la finalidad del presente proyecto, consiste en proporcionarle estabilidad a un robot autónomo de un solo eje, para lo cual se hace necesario, la implementación de un sistema de control de inclinación. El sistema de detección de inclinación desarrollado, está basado en el ultrasonido como herramienta principal de medición de distancia entre dos puntos equidistantes del eje central de la plataforma robótica, la cual es inestable por naturaleza. Mediante este nuevo método, se ha logrado establecer magnitudes de inclinación del orden de fracciones de grados, ya que los transductores piezoeléctricos en conjunto con la electrónica implementada, brinda gran precisión en las medidas realizadas

Estudio técnico-financiero para la viabilidad de un tratamiento de fracturamiento hidráulico en campo escuela Colorado.

The aim of this paper is to present the evaluation of feasibility of hydraulic fracturing job in Colorado Field wells. For this reason, it was considered for a hydraulic fracturing treatment in Colorado’s wells to be successful you must fulfill two criteria: the fracture has to be technically enforceable and economically feasible. With a production model there were selected the Wells that presented greater potential to reduce the damage in the wellbore. Later the technical evaluation was made by geomechanical characterization of lithological column which allowed setting: pore pressure, mechanical properties and stress. Intervals were selected to intervene using the petrophysical model. Within these intervals it was evaluated the feasibility of generating a hydraulic fracture by determining the type of initial failure of the rock, presence of high containment barriers of height, fracture gradient and contrast of mechanical properties. According to the Unified Fracture Design methodology it was designed the optimum fracture geometry which maximizes the well productivity. This potential incremental design was used to evaluate the economic feasibility of fracturing which allowed to establish whether the initial investment and operating cost of treatment were recovered during the treatment time.El objetivo del trabajo es presentar la evaluación de factibilidad de realizar un trabajo de fracturamiento hidráulico en pozos de Campo Colorado. Para tal fin se consideró que para que un tratamiento de fracturamiento sea exitoso se deben cumplir dos criterios: que la fractura sea técnicamente ejecutable y económicamente viable. Mediante un modelo de producción se seleccionaron los pozos que presentarían mayor potencial al disminuir el daño en cara de pozo. Posteriormente se realizó la evaluación técnica mediante la caracterización geomecánica de la formación la cual permitió establecer: presión de poro, propiedades mecánicas y esfuerzos. Se seleccionaron los intervalos a intervenir con ayuda del modelo petrofísico. A estos intervalos se le evaluó la factibilidad de generar una fractura hidráulica mediante la determinación del tipo de falla inicial de la roca, presencia de barreras de contención de altura, gradiente de fractura y contraste de propiedades mecánicas. Mediante la metodología del diseño unificado de fractura se diseñó la geometría óptima de fractura la cual maximizaría la productividad el pozo. Este potencial incremental de diseño fue utilizado para evaluar la viabilidad económica del tratamiento de fracturamiento el cual permite establecer si la inversión inicial y el costo operativo del tratamiento son recuperables durante el tiempo del tratamiento.

Molecular Tumor Board Improves Outcomes for Hispanic Patients With Advanced Solid Tumors

PURPOSEMultidisciplinary molecular tumor boards (MTBs) decode complex genomic data into clinical recommendations. Although MTBs are well-established in the oncology practice in developed countries, this strategy needs to be better explored in developing countries. Herein, we describe the possible benefits and limitations of the first MTB established in Colombia.METHODSDemographic, clinical, and genomic information was collected between August 2020 and November 2021. By mid-2020, an MTB strategy was created to discuss clinical cases with one or more genomic alterations identified by next-generation sequencing using an open-access virtual platform. We characterized the patient population as benefiting from the recommended treatment option. We assessed the benefits and access to available targeted therapies that have the potential to change clinical management by making recommendations to treating oncologists on the basis of genomic profiling. However, we did not assess the treatment oncologists' compliance with MTB recommendations because they were not intended to replace clinical judgment/standard of care.RESULTSA total of 146 patients were included in the discussions of the MTB. The median age was 59 years, and 59.6% were women. Genomic results prompting a change in therapeutic decisions were obtained in 53.1% of patients (95% CI, 44.9 to 61.3). The most prevalent malignancy was non–small-cell lung cancer (51%). Other malignancies represented 60%, 50%, and 30% of patients with soft-tissue sarcomas, brain tumors, and breast cancer, respectively.CONCLUSIONUsing an open-access virtual platform, MTBs were feasible in low- and middle-income countries on the basis of the capability to provide the benefits and access to available targeted therapies that are not standard of care. Furthermore, MTB recommendations were made available to the treating oncologist in different locations across Colombia, providing the option to modify clinical management in most of these patients

Desarrollo : prácticas y discursos emergentes en América Latina

Latinoamérica se ha constituido desde hace más de un siglo en el laboratorio para la aplicación de recetas hegemónicas para avanzar hacia el desarrollo; también ha sido el escenario en el que se han debatido y resignificado las distintas concepciones que sobre este se han puesto en marcha en la región. En este contexto han sido claves las propuestas que han surgido, desde diferentes instancias: sociedad civil organizada, academia, Estado, minorías, entre otros para repensar el concepto y construir alternativas a la visión hegemónica que sobre este se instala en América Latina. Estos procesos evidencian el tránsito permanente de una noción singular y unívoca del desarrollo que descansa fundamentalmente en garantizar el crecimiento económico a una noción plural (los desarrollos) cuyo eje reside en el ejercicio de derechos y el bienestar; o en planteamientos que pretenden ir más allá, los que por naturaleza, no son únicos sino siempre plurales, en los que prevalecen lógicas distintas a la capitalista y saberes des-centrados para construir de manera distinta la realidad

Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study

Background: Epidermal growth factor receptor (EGFR) mutations (EGFRm) represent one of the most common genomic alterations identified among patients with non-small cell lung cancer (NSCLC). Several targeted agents for patients with EGFRm have been proven safe and effective, including the third-generation tyrosine kinase inhibitor (TKI) osimertinib. Nonetheless, some patients will present with or develop EGFR-TKI resistance mechanisms. Objective: We characterized the genomic landscape of primary resistance to osimertinib among Hispanic patients with EGFR-mutant NSCLC. Methods: An observational longitudinal cohort study was conducted with two groups of patients, those with intrinsic resistance (cohort A) and those with long-term survival (cohort B). All patients were treated and followed between January 2018 and May 2022. All patients were assessed for Programmed Cell Death Ligand 1 (PD-L1) expression and Bcl-2-like protein 11 (BIM)/AXL mRNA expression before starting TKI. After 8 weeks of treatment, a liquid biopsy was performed to determine the presence of circulating free DNA (cfDNA), and next-generation sequencing (NGS) was used to identify mutations at the time of progression. In both cohorts, overall response rate (ORR), progression-free survival (PFS), and overall survival (OS) were evaluated. Results: We found a homogeneous distribution of EGFR-sensitizing mutations in both cohorts. For cohort A, exon 21 mutations were more common than exon 19 deletions (ex19dels) for cohort B (P = 0.0001). The reported ORR for osimertinib was 6.3% and 100% for cohorts A and B, respectively (P = 0.0001). PFS was significantly higher in cohort B (27.4 months vs. 3.1 months; P = 0.0001) and ex19del patients versus L858R (24.5 months, 95% confidence interval [CI] 18.2-NR), vs. 7.6 months, 95% CI 4.8-21.1; P = 0.001). OS was considerably lower for cohort A (20.1 months vs. 36.0 months; P = 0.0001) and was better for patients with ex19del, no brain metastasis, and low tumor mutation burden. At the time of progression, more mutations were found in cohort A, identifying off-target alterations more frequently, including TP53, RAS, and RB1. Conclusion: EGFR-independent alterations are common among patients with primary resistance to osimertinib and significantly impact PFS and OS. Our results suggest that among Hispanic patients, other variables associated with intrinsic resistance include the number of commutations, high levels AXL mRNA, and low levels of BIM mRNA, T790M de novo, EGFR p.L858R presence, and a high tumoral mutational burden

XVII International Congress of Control Electronics and Telecommunications: "Advanced Science, Technology and Innovation to move towards a new socio-technical system: Sustainable Social Transformation"

Contenido: Approach to the diagnostic of cesarean birth using bio-inspired models. ; Design of a tool in a virtual reality environment to manipulate anatomical models. ; The effect of COVID-19 restrictions on the electricity price forecasting models. ; Depression prevention through artificial intelligence. ; State of the art in Prototypes as complements to the learning of the Colombian Sign Language (LSC). ; A computational proposal for gene expression deterministic analysis in associated disorders to depression and anxiety. ; Evaluation of postural stability from the predictability of the measurement of the center of pressure. ; Psychophysiological Analysis of Sound Stimuli.; Delphi method for the identification of relevant variables in the development of low-power photovoltaic solar projects. ; Socioeconomic impact of a refrigerator powered by a photovoltaic system in La Guajira. ; Energy Efficiency: characteristics that allow the reduction of greenhouse gases in. ; Possibilities for the implementation of a bioreactor from organic waste. ; Energy Potential with Small Hydroelectric Power Plants in Non- interconnected Zones of Colombia. ; Energy Potential in Photovoltaic Solar Solutions in Non-Interconnected Areas of Colombia. ; Photovoltaic system, towards the energy transition from home. ; Blockchain model to increase the transparency of public sector processes. ; Intelligent agricultural irrigation prescription system based on sensor networks and crop modeling. ; Design and implementation of a digital modulation classification system using intelligent algorithms. ; A mobile application proposal to minimize intermediation during agricultural process distribution of products in supply chain. ; Accompanying strategy for the social appropriation of new technologies in vulnerable agricultural communities: case in communities producing Gulupas fruits (Passiflora edulis Sims). ; Predictive model of transparency as an indicator of Public Policies. ; Smart system for recognition of ripening level in blackberry fruits. ; Project-based learning as an alternative methodology for technological education in electronics. ; Design and construction of an automated system for N. ; Four bar mechanisms (FBM) and their Software-Based applications: a reviewFT aquaponic culture of Red Carp and Crespa Lettuce. ; Intelligent search implementation for the construction of states of the art: a python application. ; Indoor and Outdoor propagation models on 5G environments: state of the art. ;The electronic detection of offenders (DOO) in the District Secretary of mobility of Bogotá: a step forward in the configuration of the concept of digital citizenship in Colombia. ; Monitoring through ICT of Mobility: technological collaborative feature to incorporate IoT in a Smart City. ; Characterization model of asphalt mixtures using digital image processing. ; Review: identification of diseases and/or pests in fruit trees through image processing techniques and artificial intelligence. ; VRS applicated to Nasa Yuwe language. ; Application of Pix2Pix for edge reconstruction in images. ; Brushless DC Motor Control System for Active Myoelectric Prosthesis. ; Implementation of a Water Conductivity Measuring System. ; 2 DOF robot programmed with MatLab® (guide and Peter Corke) and Arduino uno for writing alphabetical characters. ; Simulator of the behavior of the center of mass in a quadruped robot. ; Biomimetic prototype for flapping movement of batsContent: Contenido: Approach to the diagnostic of cesarean birth using bio-inspired models. ; Design of a tool in a virtual reality environment to manipulate anatomical models. ; The effect of COVID-19 restrictions on the electricity price forecasting models. ; Depression prevention through artificial intelligence. ; State of the art in Prototypes as complements to the learning of the Colombian Sign Language (LSC). ; A computational proposal for gene expression deterministic analysis in associated disorders to depression and anxiety. ; Evaluation of postural stability from the predictability of the measurement of the center of pressure. ; Psychophysiological Analysis of Sound Stimuli.; Delphi method for the identification of relevant variables in the development of low-power photovoltaic solar projects. ; Socioeconomic impact of a refrigerator powered by a photovoltaic system in La Guajira. ; Energy Efficiency: characteristics that allow the reduction of greenhouse gases in. ; Possibilities for the implementation of a bioreactor from organic waste. ; Energy Potential with Small Hydroelectric Power Plants in Non- interconnected Zones of Colombia. ; Energy Potential in Photovoltaic Solar Solutions in Non-Interconnected Areas of Colombia. ; Photovoltaic system, towards the energy transition from home. ; Blockchain model to increase the transparency of public sector processes. ; Intelligent agricultural irrigation prescription system based on sensor networks and crop modeling. ; Design and implementation of a digital modulation classification system using intelligent algorithms. ; A mobile application proposal to minimize intermediation during agricultural process distribution of products in supply chain. ; Accompanying strategy for the social appropriation of new technologies in vulnerable agricultural communities: case in communities producing Gulupas fruits (Passiflora edulis Sims). ; Predictive model of transparency as an indicator of Public Policies. ; Smart system for recognition of ripening level in blackberry fruits. ; Project-based learning as an alternative methodology for technological education in electronics. ; Design and construction of an automated system for N. ; Four bar mechanisms (FBM) and their Software-Based applications: a reviewFT aquaponic culture of Red Carp and Crespa Lettuce. ; Intelligent search implementation for the construction of states of the art: a python application. ; Indoor and Outdoor propagation models on 5G environments: state of the art. ;The electronic detection of offenders (DOO) in the District Secretary of mobility of Bogotá: a step forward in the configuration of the concept of digital citizenship in Colombia. ; Monitoring through ICT of Mobility: technological collaborative feature to incorporate IoT in a Smart City. ; Characterization model of asphalt mixtures using digital image processing. ; Review: identification of diseases and/or pests in fruit trees through image processing techniques and artificial intelligence. ; VRS applicated to Nasa Yuwe language. ; Application of Pix2Pix for edge reconstruction in images. ; Brushless DC Motor Control System for Active Myoelectric Prosthesis. ; Implementation of a Water Conductivity Measuring System. ; 2 DOF robot programmed with MatLab® (guide and Peter Corke) and Arduino uno for writing alphabetical characters. ; Simulator of the behavior of the center of mass in a quadruped robot. ; Biomimetic prototype for flapping movement of bat

Biodiversidad 2017. Estado y tendencias de la biodiversidad continental de Colombia

En la cuarta versión del Reporte, que corresponde al año 2017, es una obligación preguntarnos cuál ha sido y es el papel de esta publicación y si ha abarcado la diversidad de formas y conceptos que definen el estado y el futuro de la biodiversidad colombiana. Las temáticas que constituyen la columna vertebral de cada uno de los reportes anuales responden a temas de pertinencia, nivel de incidencia y actualidad desde cada uno de los diferentes niveles de organización de la biodiversidad y buscan responder las siguientes preguntas fundamentales: 1) ¿Cómo se encuentra la biodiversidad del país? 2)¿Qué factores, en dónde y en qué medida está siendo afectada? 3)¿Cuáles son las iniciativas que desde la sociedad civil o a nivel de políticas públicas buscan evitar esa pérdida? 4)¿Cuáles son las grandes oportunidades para mejorar su gestión y manejo? Si bien evaluar la incidencia que puede tener el Reporte sobre acciones de gestión no es tarea fácil, se debe reconocer la buena acogida que han tenido los textos, las ilustraciones y la cifras entre los distintos tipos de lectores y el papel fundamental que ha jugado el Reporte en comunicar información de altísima calidad sobre la biodiversidad colombiana en diferentes momentos coyunturales. En ese sentido esta publicación es cada vez más una herramienta de consulta y referencia que está abierta al público tanto en formato impreso como digital, y de la misma manera busca fortalecerse para continuar brindando información relevante para la toma de decisiones en materia ambiental.BogotáSubdirección de Investigacione