5,228 research outputs found
A study of the pi^0pi^0 system produced in charge exchange and central collisions
A study of the system produced in charge exchange
collisions at 38 and 100 GeV/c and in central interactions at 450 GeV/c
has been carried out. The wave has rather a complicated structure in both
processes indicating the existence of several scalar resonances. The
and appear as dips at 1 and 1.5 GeV in the wave for charge
exchange reaction, and as shoulders at these masses in the wave for central
production. The production of the , and in
the reaction as a function of the
kinematical filter shows the behaviour differed from what has been observed for
the undisputed mesons. An extra state is seen in the
wave for charge exchange reaction as a dip at 2 GeV. Resonances with higher
spins, , and , have also been studied. All
the three mesons are produced in the reaction mainly
via an one-pion exchange for small , whereas a natural-parity exchange
domimates for large . The behaviour of the centrally produced
as a function of the is consistent with what has been observed for
other states.Comment: 6 pages, 6 figures, use file stwol.sty, presented at International
High-Energy Physics Euroconference in Quantum Chromodynamics, 2-8 July 1998,
Montpellier, France on behalf of the GAMS and WA102 Collaboration
Measuring beauty production in Pb-Pb collisions at the LHC via single electrons in ALICE
We present the expected ALICE performance for the measurement of the
p_t-differential cross section of electrons from beauty decays in central Pb-Pb
collisions at the LHC.Comment: 4 pages, 2 figures, proceeding of poster presentation at "Quark
Matter 2005
Strangeness enhancements at central rapidity in 40 A GeV/c Pb-Pb collisions
Results are presented on neutral kaon, hyperon and antihyperon production in
Pb-Pb and p-Be interactions at 40 GeV/c per nucleon. The enhancement pattern
follows the same hierarchy as seen in the higher energy data - the enhancement
increases with the strangeness content of the hyperons and with the centrality
of collision. The centrality dependence of the Pb-Pb yields and enhancements is
steeper at 40 than at 158 A GeV/c. The energy dependence of strangeness
enhancements at mid-rapidity is discussed.Comment: 15 pages, 10 figures and 3 tables. Presented at International
Conference on Strangeness in Quark Matter (SQM2009), Buzios, Rio de Janeiro,
Brazil, 27 Sept - 2 Oct 2009. Submitted to J.Phys.G: Nucl.Part.Phys, one
reference adde
Optimizing HIV therapy. A consensus project on differences between cytidine analogues and regime compactness
The identification of the most effective HAART regimens in different clinical settings is still an issue. The aim of the study was to analyze how the compactness of HAART regimens is perceived and if differences between lamivudine (3TC) and emtricitabine (FTC) do exist according to a panel of Italian HIV/AIDS clinicians, using the Delphi method
Charge Particle Multiplicity and Transverse Energy Measurements in Au-Au collisions in PHENIX at RHIC
We present results on charged particle and transverse energy densities
measured at mid-rapidity in Au-Au collisions at sqrt(s_{NN})=200 GeV. The mean
transverse energy per charged particle is derived. The results are presented as
a function of centrality, which is defined by the number of participating
nucleons, and compared to results obtained in Au-Au collisions at
sqrt{s_{NN})=130 GeV. A comparison with calculations from various theoretical
models is performed.Comment: 4 pages, 5 figures. Talk presented at Quark Matter 2002, Nantes,
France, July 18-24, 2002. To appear in the proceedings (Nucl. Phys. A
Recent Results on Strangeness Production at RHIC
Due to its large acceptance, the STAR experiment has acquired a wealth of
data on strangeness production for a variety of collisions systems and
energies, from p+p to Au+Au. By using the yields and spectra, we address the
evolution of the bulk system, including strangeness enhancement and the flavour
dependence of radial and elliptic flow. Utilising the fact that we can identify
strange baryons and mesons, we investigate different hadronization mechanisms
in the intermediate and high p regions. The ratios of the particle
yields, measured to high p, are used to further investigate the range and
applicability of the previously reported anomalous baryon production. We also
study two-particle azimuthal correlations of identified particles in order to
investigate any flavour dependence of jet fragmentation in the available
p range. Data was presented for a number of different collision systems
and energies.Comment: Proceedings of SQM'06 Conference, LA, 2006 (submitted to J. Phys. G
Self-reported adherence supports patient preference for the single tablet regimen (STR) in the current cART era
Objective: To analyze self-reported adherence to antiretroviral regimens containing ritonavir-boosted protease inhibitors, non-nucleoside reverse transcriptase inhibitors (NNRTI), raltegravir, and maraviroc. Methods: Overall, 372 consecutive subjects attending a reference center for HIV treatment in Florence, Italy, were enrolled in the study, from December 2010 to January 2012 (mean age 48 years). A self-report questionnaire was filled in. Patients were defined as “non-adherent” if reporting one of the following criteria:<90% of pills taken in the last month, ≥1 missed dose in the last week, spontaneous treatment interruptions reported, or refill problems in the last 3 months. Gender, age, CD4, HIV-RNA, years of therapy, and type of antiretroviral regimen were analyzed with respect to adherence. Results: At the time of the questionnaire, 89.8% of patients had <50 copies/mL HIV-RNA and 14.2% were on their first combined antiretroviral therapy. 57% of patients were prescribed a regimen containing ritonavir boosted protease inhibitors (boosted PI), 41.7% NNRTI, 17.2% raltegravir, and 4.8% maraviroc; 49.5% of the subjects were on bis-in-die regimens, while 50.5% were on once-daily regimens, with 23.1% of these on the single tablet regimen (STR): tenofovir/emtricitabine/efavirenz. The non-adherence proportion was lower in NNRTI than in boosted-PI treatments (19.4% vs 30.2%), and even lower in STR patients (17.4%). In multivariable logistic regression, patients with the NNRTI regimen (OR: 0.56, 95% CI: 0.34–0.94) and the STR (OR: 0.45, 95% CI: 0.22–0.92) reported lower non-adherence. Efavirenz regimens were also associated with lower non-adherence (OR: 0.42, 95% CI: 0.21–0.83), while atazanavir/ritonavir regimens were associated with higher non-adherence. No other relation to specific antiretroviral drugs was found. A higher CD4 count, lower HIV-RNA, and older age were also found to be associated with lower non-adherence, while a longer time on combined antiretroviral therapy was related to higher non-adherence. Conclusion: In conclusion, older age, higher CD4 cell counts, lower HIV-RNA viral loads, and the use of STR are all related to lower non-adherence. In particular, the use of STR maintains an advantage in improving adherence with respect to other cARTs, even with the availability of new, well-tolerated antiretroviral drugs and drug classes in recent years
Adherence in HIV-positive patients treated with single-tablet regimens and multi-pill regimens: findings from the COMPACT study
The use of Combination AntiRetroviral Therapy (cART) has decreased the morbidity and mortality of patients infected with HIV. However, adherence to cART remains crucial to prevent virological failure and disease progression. The aim of this study was to assess adherence to treatment among patients treated with Single Tablet Regimen (STR) or with multi-pill regimens based on Protease Inhibitors (PI), Non-Nucleoside Reverse-Transcriptase Inhibitors (NNRTI), or raltegravir (RAL). An observational retrospective cohort analysis based on administrative and clinical databases was conducted at the National Institute for Infectious Diseases (Rome, Italy). HIV-positive patients treated with a cART between Jan 1st, 2008–Dec 31st, 2010 were included. Patients were followed-up for one year since the first prescription during the inclusion period or up to death or switch of at least one drug of the regimen. Adherence and selective non-adherence (days without backbone or 3rd drug) were calculated using pharmacy refill compliance [1]. cART regimens were classified based on number of daily pills (STR vs multi-pill regimen) and on type of third drug. Viral Load (VL) and CD4 cell counts at the end of the follow-up were evaluated. A total of 1,604 patients were analyzed, 70.0% male, age 45.0±8.7, 14.3% newly treated. Patients on STR were 159 (9.9%), PI 878 (54.7%), NNRTI 523 (32.6%), RAL 44 (2.7%). Presence of at least one AIDS-defining conditions (according to Centers for Disease Control classification) was 30% in the STR group, 34% PI, 26% NNRTI, 34% RAL (p=n.s.). Adherence was 80.4±14.7% for STR, 71.8±21.8% PI, 77.1±20.3% NNRTI, 74.0±22.4% RAL. Selective non-adherence was 5.5% (18 days) PI, 2.8% (8 days) NNRTI, 12.5% (43 days) RAL (Figure 1). At the end of the follow-up, VL/CD4 values were available among 709 patients (44%); CD4 count >500 cell/mm3 was observed among 61% of patients on STR, 44% PI, 48% NNRTI, 42% RAL and VL < 50 copies/ml was observed among 96% of patients on STR, 78% PI, 88% NNRTI, 87% RAL. Interruptions in cART refill remain a relevant problem across all cART regimens. Patients on STR displayed a higher adherence rate compared to multi-pill regimes (PI, NNRTI, and RAL), primarily due to lack of selective non-adherence. Patients on STR experienced also higher rates of VL < 50 and CD4 > 500. The use of an STR regimen appears an effective therapeutic option to avoid selective non-adherence and, consequently, to prevent virological failure and disease progression
Strangeness, Charm and Beauty in Quark Matter: SQM 2007 Experimental Overview
This paper aims at providing an experimental overview of the Strangeness in
Quark Matter 2007 ConferenceComment: Proceedings of Strangeness in Quark Matter 2007, submitted to Journal
of Physics
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