527 research outputs found

    Returning children from public care

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    Research Briefing 4

    Between plateau and plain: flexible responses to varied environments in Southwestern Australia

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    Major Themes in the Novels of Kurt Vonnegut, Jr.

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    Kurt Vonnegut, Jr. has written six novels which explore some of the most important problems confronting man in contemporary society. Little significant criticism has been written on Kurt Vonnegut since he began writing in 1949. Recently, however, he has experienced an increasing popularity with readers and critics who have found his novels successful probings into modern man’s feelings of alienation in a world which he perceives as increasingly absurd. This thesis is an analysis of Kurt Vonnegut’s use of black humor, satire and science fiction devices in his exploration of four major themes occurring throughout his novels: criticisms of science, religion, society and war

    M.A. Program in Folklore at the University of California at Berkeley

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    Topics and Comment

    SCAFFOLDING IN INTERPROFESSIONAL EDUCATION: IMPLICATIONS FOR SOCIAL WORK EDUCATION

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    Indiana University-Purdue University Indianapolis (IUPUI)Medical errors due to failure to communicate and collaborate are one of the top causes of death in the United States. Interprofessional education (IPE) is an integrated instructional approach where various health care disciplines create opportunities for students to learn together in order to function as cohesive, effective, and collaborative interprofessional teams. Successful IPE program design is a multi-faceted challenge, especially for social work educators in light of the changes in EPAS 2015. Academic institutions are being encouraged to offer IPE programs; faculty members are then charged with developing IPE programs for their institutions. IPE program design could generate a multitude of advantages for students, faculty, academic programs, professions, university partners, and communities—provided the approach is systematic and inclusive. This prospectus will explore IPE program design in field settings for social work faculty as a scaffold design, which targets proactive understanding of resources and applications. The prospectus will explore three interrelated special considerations: 1) the connections between IPE and social work education; 2) the learning needs (learning styles and fear of negative evaluation) of students most likely to be invited to participate in an IPE program; and 3) the needs of field instructors and needs of social work students in relation to their field experience. Social work faculty as program developers new to IPE will gain insights from this work and be better able to concurrently layer educational outcomes with professional gains, while initiating opportunities for interprofessional collaborative practice skill-building in field settings—ultimately enhancing health outcomes

    Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation

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    Mesenchymal cell motility is driven by polarized actin polymerization [1]. Signals at the leading edge recruit actin polymerization machinery to promote membrane protrusion, while matrix adhesion generates tractive force to propel forward movement. To work effectively, cell motility is regulated by a complex network of signaling events that affect protein activity and localization. H2O2 has an important role as a diffusible second messenger [2], and mediates its effects through oxidation of cysteine thiols. One cell activity influenced by H2O2 is motility [3]. However, a lack of sensitive and H2O2-specific probes for measurements in live cells has not allowed for direct observation of H2O2 accumulation in migrating cells or protrusions. In addition, the identities of proteins oxidized by H2O2 that contribute to actin dynamics and cell motility have not been characterized. We now show, as determined by fluorescence lifetime imaging microscopy, that motile cells generate H2O2 at membranes and cell protrusions and that H2O2 inhibits cofilin activity through oxidation of cysteines 139 (C139) and 147 (C147). Molecular modeling suggests that C139 oxidation would sterically hinder actin association, while the increased negative charge of oxidized C147 would lead to electrostatic repulsion of the opposite negatively charged surface. Expression of oxidation-resistant cofilin impairs cell spreading, adhesion, and directional migration. These findings indicate that H2O2 production contributes to polarized cell motility through localized cofilin inhibition and that there are additional proteins oxidized during cell migration that might have similar roles

    Building a User Sensitive Intelligent Portal to Breast Cancer Knowledge To Meet Diverse Information Needs

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    The Internet provides access to a plethora of information, with health information being no exception. Portals for guiding users seeking health knowledge are proliferating. A major challenge in their development is filtering the information available in a user-sensitive way. The Breast Cancer Knowledge Online (BCKOnline) project addresses the challenge of meeting the diverse information needs of women with breast cancer and their families through the provision of timely, relevant and reliable information to support decision-making. This paper focuses on how the outcomes of user needs analysis and user-aware resource description will feed into building an intelligent portal prototype to breast cancer knowledge

    What Part Should the United States Play in the War?

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    Radio transcript of Lindenwood College students debating whether or not the United States should join World War II. circa April 1941

    Planetary Science Technology Infusion Study: Findings and Recommendations Status

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    The Planetary Science Division (PSD) within the National Aeronautics and Space Administrations (NASA) Science Mission Directorate (SMD) at NASA Headquarters sought to understand how to better realize a scientific return on spacecraft system technology investments currently being funded. In order to achieve this objective, a team at NASA Glenn Research Center was tasked with surveying the science and mission communities to collect their insight on technology infusion and additionally sought inputs from industry, universities, and other organizations involved with proposing for future PSD missions. This survey was undertaken by issuing a Request for Information (RFI) activity that requested input from the proposing community on present technology infusion efforts. The Technology Infusion Study was initiated in March 2013 with the release of the RFI request. The evaluation team compiled and assessed this input in order to provide PSD with recommendations on how to effectively infuse new spacecraft systems technologies that it develops into future competed missions enabling increased scientific discoveries, lower mission cost, or both. This team is comprised of personnel from the Radioisotope Power Systems (RPS) Program and the In-Space Propulsion Technology (ISPT) Program staff.The RFI survey covered two aspects of technology infusion: 1) General Insight, including: their assessment of barriers to technology infusion as related to infusion approach; technology readiness; information and documentation products; communication; integration considerations; interaction with technology development areas; cost-capped mission areas; risk considerations; system level impacts and implementation; and mission pull. 2) Specific technologies from the most recent PSD Announcements of Opportunities (AOs): The Advanced Stirling Radioisotope Generator (ASRG), aerocapture and aeroshell hardware technologies, the NASA Evolutionary Xenon Thruster (NEXT) ion propulsion system, and the Advanced Materials Bi-propellant Rocket (AMBR) engine.This report will present the teams Findings from the RFI inputs and the recommendations that arose from these findings. Methodologies on the findings and recommendations development are discussed
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