Biblioteconomia e Ciência da Informação: uma análise paradigmática em bibliotecas públicas

Documento em formato pdf referente à artigo "Biblioteconomia e Ciência da Informação: uma análise paradigmática em bibliotecas públicas" de Ana Carolina de Melo Martins, Crislaine Zurilda Silveira, Elisa Cristina Delfini Corrêa e Jordan Paulesky Julian.O objetivo do presente estudo é fazer uma análise de duas bibliotecas públicas do Estado de Santa Catarina norteada pelos paradigmas da Biblioteconomia e da Ciência da Informação tendo em vista verificar qual o paradigma dominante nessas unidades de informação. Para tanto, foi apresentada um breve panorama histórico da Biblioteconomia e da Ciência da Informação, bem como os seus paradigmas norteadores e o conceito de biblioteca pública. A observação sistemática foi utilizada como uma forma de coletar os dados in loco das unidades de informação. Foram descritas as características das unidades investigadas, bem como os pontos paradigmáticos observados. Em seguida, foram apresentadas algumas perspectivas futuras para as bibliotecas públicas, com sugestões referentes a inclusão da comunidade e a adoção de TIC. Nas considerações finais é sugerida a criação de políticas públicas que destinem orçamentos fixos para essas instituições, a fim de que elas possam investir em acervos e dispositivos tecnológicos que atendam às necessidades da comunidade. Localização apenas no formato digital

The sealing ability of MTA apical plugs exposed to a phosphate-buffered saline

OBJECTIVE: The aim of this study was to evaluate the influence of exposure of the mineral trioxide aggregate (MTA) - with and without calcium chloride (CaCl2) - to phosphate-buffered saline (PBS) on the apical microleakage using a glucose leakage system. MATERIAL AND METHODS: Sixty root segments were randomly divided into 4 experimental groups (n=15). After resecting the apical segments and enlarging the canals with Gates-Glidden drills, the apical cavities were filled with MTA with or without CaCl2 and the root canals were dressed with a moistened cotton pellet or PBS, as follows: 1) MTA/cotton pellet; 2) MTA/PBS; 3) MTA+10%CaCl2/cotton pellet; 4) MTA+10%CaCl2/PBS. All root segments were introduced in floral foams moistened with PBS. After 2 months, all root segments were prepared to evaluate the glucose leakage along the apical plugs. The amount of glucose leakage was measured following an enzymatic reaction and quantified by a spectrophotometer. Four roots were used as controls. The data were analyzed using Kruskal-Wallis and Mann-Whitney tests (p;0.05), and 3 and 4 (p>;0.05). The addition of CaCl2 to the MTA significantly decreased its sealing ability (

Dental and composite resin discoloration induced by different hydraulic calcium silicate-based cements: two-year in vitro assessment

Few long-term studies assess the discoloration induced by hydraulic calcium silicate-based cement on dental structures. In addition, as far as we know, no long-term study has assessed the discoloration induced by these cement on composite resin. Objective: This in vitro study aimed to assess, during a period of two years, the discoloration potential of different hydraulic calcium silicate-based cements (hCSCs) on the enamel/dentin structure and composite resin restoration. Methodology: A total of 40 enamel/dentin discs were obtained from bovine incisors, and 40 composite resin discs (10 mm in diameter × 2 mm thick) were fabricated. A 0.8 mm-deep cavity was made in the center of each disc and filled with the following hCSCs (n=10): Original MTA (Angelus); MTA Repair HP (Angelus); NeoMTA Plus (Avalon); and Biodentine (Septodont). An initial color measurement was performed (T0 - baseline). After 7, 15, 30, 45, 90, 300 days, and two years, new color measurements were performed to determine the color (ΔE00), lightness (ΔL’), chroma (ΔC’), hue differences (ΔH’), and whiteness index (WID). Results: For enamel/dentin, the ΔE00 was significant among groups and periods (p<0.05). NeoMTA Plus had the greatest ΔE00. The NeoMTA Plus group had the greatest ΔE00 after two years for composite resin. Significant reduction in lightness was observed for all groups after two years (p<0.05). The most significant WID values were observed after 30 days for Biodentine (enamel/dentin) and MTA Repair HP groups (composite resin) (p<0.05). Conclusions: The hCSCs changed the colorimetric behavior of both substrates, leading to greater darkening over time. The Bi2O3 in the Original MTA seems relevant in the short periods of color change assessment

Diabetes Gestacional como Causa de Crescimento Intrauterino Restrito e seus Desfechos Tardios / Gestational Diabetes as a Cause of Restricted Intrauterine Growth and its Late Outcomes

INTRODUÇÃO: Considera-se Diabetes Mellitus Gestacional (DMG) a intolerância aos carboidratos iniciada na gestação. O DMG está associado a um risco aumentado de complicações fetais, como o Crescimento Intrauterino Restrito (CIUR), alteração em que o feto apresenta crescimento inferior ao normal (dentro do previsto pelo seu potencial genético), com repercussões variáveis na sua saúde. METODOLOGIA: Trata-se de uma revisão narrativa de caráter descritivo e explicativo. A pesquisa bibliográfica foi feita nas bases de dados PubMed, Scielo e LILACS. Os descritores utilizados foram: diabetes mellitus gestacional, resistência insulínica materna e restrição do crescimento intrauterino. RESULTADOS: Foram avaliadas as sequelas de curto e longo prazos de crianças com CIUR ou filhos de mães com DMG, como a presença de  macrossomia, pré eclâmpsia, entre outros. DISCUSSÃO:  O CIUR, no contexto de DMG, tende a ocorrer em mulheres portadoras de doença vascular crônica e tem como fatores de risco o IMC elevado, hipertensão arterial e doença renal. CONCLUSÃO: Além do acompanhamento do pré-natal adequado, é de extrema importância a pediatria viabilizar estratégias preventivas e de tratamento em bebês CIUR, de modo a evitar suas consequências

Monocytes presenting a pro-inflammatory profile persist in patients submitted to a long-term pharmacological treatment after acute myocardial infarction

Introduction: Although it is broadly known that monocyte recruitment is involved in atherosclerosis development and that, in accordance with the microenvironment, these cells can be modulated into three well-known subpopulations: Classical (CD14++CD16−), intermediate (CD14++CD16+), and non-classical (CD14+CD16++), the effects of treatment with different pharmacological strategies (based on lipid-lowering and antiplatelets) after acute myocardial infarction upon the monocytes modulation and the role of the chemokine receptors CCR2, CCR5 and CX3CR1 in this context, are poorly understood.Methods: In this study, patients [n = 148, both men (n = 105, 71%) and women (n = 43, 29%)] submitted to treatment with a 2×2 factorial design, in which they received rosuvastatin 20 mg or simvastatin 40 mg plus ezetimibe 10 mg, as well as ticagrelor 90 mg or clopidogrel 75 mg were enrolled. Monocyte subsets were analyzed by flow cytometry at baseline (BL), and after one (1-M) and 6 months (6-M) of treatment.Results: Firstly, our results showed that, regardless of the treatment received, higher percentages of classical monocytes and lower of non-classical monocytes were found at the 6-M time point than BL values, whilst the percentage of intermediate monocytes was higher in all time points assessed than the other subsets. There were reductions in the CCR2 expression by non-classical and intermediate monocytes, without differences for the classical subtype. Concerning the CCR5 expression, there were reductions in the three monocyte subtypes, whereas the CX3CR1 expression increased both in intermediate and classical monocytes, without differences for non-classical monocytes. In relation to the treatment received, a higher percentage of intermediate monocytes at the 6-M time point than the values BL was observed in the group treated with simvastatin + ezetimibe + clopidogrel. No significant differences were found concerning non-classical, intermediate, and classical monocytes, for CCR2, CCR5, and CX3CR1 in the four treatment arms.Conclusion: Taken together, our results demonstrated that even under lipid-lowering and antiplatelet therapy for 6 months, the inflammatory phenotype of monocytes still persisted in the patients enrolled in this study

Dynamics and determinants of SARS-CoV-2 RT-PCR testing on symptomatic individuals attending healthcare centers during 2020 in Bahia, Brazil

RT-PCR testing data provides opportunities to explore regional and individual determinants of test positivity and surveillance infrastructure. Using Generalized Additive Models, we explored 222,515 tests of a random sample of individuals with COVID-19 compatible symptoms in the Brazilian state of Bahia during 2020. We found that age and male gender were the most significant determinants of test positivity. There was evidence of an unequal impact among socio-demographic strata, with higher positivity among those living in areas with low education levels during the first epidemic wave, followed by those living in areas with higher education levels in the second wave. Our estimated probability of testing positive after symptom onset corroborates previous reports that the probability decreases with time, more than halving by about two weeks and converging to zero by three weeks. Test positivity rates generally followed state-level reported cases, and while a single laboratory performed ~90% of tests covering ~99% of the state's area, test turn-around time generally remained below four days. This testing effort is a testimony to the Bahian surveillance capacity during public health emergencies, as previously witnessed during the recent Zika and Yellow Fever outbreaks

Abordagens terapêuticas inovadoras na gestão da dor crônica: uma síntese de evidências

Inovações terapêuticas, como o uso de células-tronco mesenquimais e plasma rico em plaquetas, oferecem avanços promissores na gestão da dor crônica, proporcionando não apenas alívio imediato, mas também abordando as causas subjacentes para melhorar a qualidade de vida dos pacientes. Este estudo teve como objetivo desenvolver uma síntese de evidências sobre abordagens terapêuticas inovadoras na gestão da dor crônica. Nesse sentido, foi desenvolvida uma revisão sistemática da literatura, utilizando Scielo, Lilacs e Medline como bases de dados. A partir da análise qualitativa dos resultados, concluiu-se que abordagens terapêuticas inovadoras, como fisioterapia, terapias cognitivo-comportamentais e intervenções farmacológicas específicas, são eficazes na gestão da dor crônica. A ênfase na personalização do tratamento, considerando a diversidade da condição, destaca-se como crucial para otimizar resultados