How to Teach Quantum Mechanics

I distinguish between two conceptually different kinds of physical space: a space of ordinary material bodies, which is the space of points at which I could imaginably place (say) the tip of my finger, or the center of a billiard-ball, and a space of elementary physical determinables, which is the smallest space of points such that stipulating what is happening at each one of those points, at every time, amounts to an exhaustive physical history of the universe. In all classical physical theories, these two spaces happen to coincide – and what we mean by calling a theory “classical”, and all we mean by calling a theory “classical”, is (I will argue) precisely that these two spaces coincide. But once the distinction between these two spaces in on the table, it becomes clear that there is no logical or conceptual reason why they must coincide – and it turns out (and this is the main topic of the present paper) that a very simple way of pulling them apart from one another gives us quantum mechanics

How to Teach Quantum Mechanics

I distinguish between two conceptually different kinds of physical space: a space of ordinary material bodies, which is the space of points at which I could imaginably place (say) the tip of my finger, or the center of a billiard-ball, and a space of elementary physical determinables, which is the smallest space of points such that stipulating what is happening at each one of those points, at every time, amounts to an exhaustive physical history of the universe. In all classical physical theories, these two spaces happen to coincide – and what we mean by calling a theory “classical”, and all we mean by calling a theory “classical”, is (I will argue) precisely that these two spaces coincide. But once the distinction between these two spaces in on the table, it becomes clear that there is no logical or conceptual reason why they must coincide – and it turns out (and this is the main topic of the present paper) that a very simple way of pulling them apart from one another gives us quantum mechanics

Reviving a national strategy roadmap for organ and tissue donation in South Africa

In September 2019, a two-day workshop ahead of the Southern African Transplantation Society congress brought together South African champions for organ donation and leaders from the International Society of Organ Donation and Procurement (ISODP) at a high-level workshop focused on creating a national strategy roadmap to improve organ donation in South Africa. The full report is available via the supplementary materials on the African Journal of Nephrology website

How to Teach Quantum Mechanics

I distinguish between two conceptually different kinds of physical space: a space of ordinary material bodies, which is the space of points at which I could imaginably place (say) the tip of my finger, or the center of a billiard-ball, and a space of elementary physical determinables, which is the smallest space of points such that stipulating what is happening at each one of those points, at every time, amounts to an exhaustive physical history of the universe. In all classical physical theories, these two spaces happen to coincide – and what we mean by calling a theory “classical”, and all we mean by calling a theory “classical”, is (I will argue) precisely that these two spaces coincide. But once the distinction between these two spaces in on the table, it becomes clear that there is no logical or conceptual reason why they must coincide – and it turns out (and this is the main topic of the present paper) that a very simple way of pulling them apart from one another gives us quantum mechanics

How to Teach Quantum Mechanics

I distinguish between two conceptually different kinds of physical space: a space of ordinary material bodies, which is the space of points at which I could imaginably place (say) the tip of my finger, or the center of a billiard-ball, and a space of elementary physical determinables, which is the smallest space of points such that stipulating what is happening at each one of those points, at every time, amounts to an exhaustive physical history of the universe. In all classical physical theories, these two spaces happen to coincide – and what we mean by calling a theory “classical”, and all we mean by calling a theory “classical”, is (I will argue) precisely that these two spaces coincide. But once the distinction between these two spaces in on the table, it becomes clear that there is no logical or conceptual reason why they must coincide – and it turns out (and this is the main topic of the present paper) that a very simple way of pulling them apart from one another gives us quantum mechanics

Book Symposium: David Albert, After Physics

On April 1, 2016, at the Annual Meeting of the Pacific Division of the American Philosophical Association, a book symposium, organized by Alyssa Ney, was held in honor of David Albert’s After Physics (Harvard University Press, 2015). All participants agreed that it was a valuable and enlightening session. We have decided that it would be useful, for those who weren’t present, to make our remarks publicly available. Please bear in mind that what follows are remarks prepared for the session, and that on some points participants may have changed their minds in light of the ensuing discussion

Identifying dynamical modules from genetic regulatory systems: applications to the segment polarity network

BACKGROUND It is widely accepted that genetic regulatory systems are 'modular', in that the whole system is made up of smaller 'subsystems' corresponding to specific biological functions. Most attempts to identify modules in genetic regulatory systems have relied on the topology of the underlying network. However, it is the temporal activity (dynamics) of genes and proteins that corresponds to biological functions, and hence it is dynamics that we focus on here for identifying subsystems. RESULTS Using Boolean network models as an exemplar, we present a new technique to identify subsystems, based on their dynamical properties. The main part of the method depends only on the stable dynamics (attractors) of the system, thus requiring no prior knowledge of the underlying network. However, knowledge of the logical relationships between the network components can be used to describe how each subsystem is regulated. To demonstrate its applicability to genetic regulatory systems, we apply the method to a model of the Drosophila segment polarity network, providing a detailed breakdown of the system. CONCLUSION We have designed a technique for decomposing any set of discrete-state, discrete-time attractors into subsystems. Having a suitable mathematical model also allows us to describe how each subsystem is regulated and how robust each subsystem is against perturbations. However, since the subsystems are found directly from the attractors, a mathematical model or underlying network topology is not necessarily required to identify them, potentially allowing the method to be applied directly to experimental expression data

Book Symposium: David Albert, After Physics

On April 1, 2016, at the Annual Meeting of the Pacific Division of the American Philosophical Association, a book symposium, organized by Alyssa Ney, was held in honor of David Albert’s After Physics (Harvard University Press, 2015). All participants agreed that it was a valuable and enlightening session. We have decided that it would be useful, for those who weren’t present, to make our remarks publicly available. Please bear in mind that what follows are remarks prepared for the session, and that on some points participants may have changed their minds in light of the ensuing discussion

On the mechanism of the digold(I) hydroxide-catalyzed hydrophenoxylation of alkynes

Herein we present a detailed investigation of the mechanistic aspects of the dual gold-catalysed hydrophenoxylation of alkynes, using both experimental and computational methods. The dissociation of [{Au(NHC)}2(µ-OH)][BF4] is essential to enter the catalytic cycle; this step is favored in the presence of bulky, non-coordinating counterions. Moreover, in silico studies confirmed that phenol does not only act as a reactant, but as a co-catalyst, lowering the energy barriers for several transition states. A gem-diaurated species might form during the reaction, but this lies deep within a potential energy well, and is likely to be an ‘off-cycle’ rather than an ‘in-cycle’ intermediate