2,479 research outputs found
HyperArc multiple brain metastases report
This report presents the initial clinical experience with HyperArc, a novel modality that incorporates a non-coplanar, arc-based multileaf collimator (MLC) and automated treatment optimization and dose delivery. The study focuses on a patient who had previously received whole-brain radiotherapy. The effectiveness and challenges of HyperArc were assessed by evaluating various quality indices for stereotactic radiosurgery within the RTOG protocol, as well as an additional measure of toxicity in the form of the V12Gy volume. The HyperArc plan achieved quality indices of 1.13, 4.58, and 0.88 for CI, GI, and CIPaddick, respectively. The mean ICRU83 value was 0.17±0.01, and it remained consistent across all six lesions. The V12Gy value was equal to 8.76 cc. The HyperArc plan successfully met the constraints for organs-at-risk (OAR). These results suggest that HyperArc is a suitable modality for treating multiple brain metastases, as indicated by the quality indices and metrics. Additionally, V12Gy is a valuable indicator for assessing low-dose spillage
Optimization of Apodized Pupil Lyot Coronagraph for ELTs
We study the optimization of the Apodized Pupil Lyot Coronagraph (APLC) in
the context of exoplanet imaging with ground-based telescopes. The APLC
combines an apodization in the pupil plane with a small Lyot mask in the focal
plane of the instrument. It has been intensively studied in the literature from
a theoretical point of view, and prototypes are currently being manufactured
for several projects. This analysis is focused on the case of Extremely Large
Telescopes, but is also relevant for other telescope designs.
We define a criterion to optimize the APLC with respect to telescope
characteristics like central obscuration, pupil shape, low order segment
aberrations and reflectivity as function of the APLC apodizer function and mask
diameter. Specifically, the method was applied to two possible designs of the
future European-Extremely Large Telescope (E-ELT).
Optimum configurations of the APLC were derived for different telescope
characteristics. We show that the optimum configuration is a stronger function
of central obscuration size than of other telescope parameters. We also show
that APLC performance is quite insensitive to the central obscuration ratio
when the APLC is operated in its optimum configuration, and demonstrate that
APLC optimization based on throughput alone is not appropriate.Comment: 9 pages, 17 figures, accepted for publication in Astronomy &
Astrophysic
On-sky observations with an achromatic hybrid phase knife coronagraph in the visible
CONTEXT: The four-quadrant phase mask stellar coronagraph, introduced by D.
Rouan et al., is capable of achieving very high dynamical range imaging and was
studied in the context of the direct detection of extra-solar planets.
Achromatic four-quadrant phase mask is currently being developed for broadband
IR applications. AIMS: We report on laboratory and on-sky tests of a prototype
coronagraph in the visible. This prototype, the achromatic hybrid phase knife
coronagraph, was derived from the four-quadrant phase mask principle. METHODS:
The instrumental setup implementing the coronagraph itself was designed to
record the pre- and post-coronagraphic images simultaneously so that an
efficient real-time image selection procedure can be performed. We describe the
coronagraph and the associated tools that enable robust and repeatable
observations. We present an algorithm of image selection that has been tested
against the real on-sky data of the binary star HD80081 (* 38 Lyn). RESULTS
Although the observing conditions were poor, the efficiency of the proposed
method is proven. From this experiment, we derive procedures that can apply to
future focal instruments associating adaptive optics and coronagraphy,
targeting high dynamic range imaging in astronomy, such as detecting
extra-solar planets
Adaptive optics imaging of P Cygni in Halpha
We obtained Halpha diffraction limited data of the LBV star P Cyg using the
ONERA Adaptive Optics (AO) facility BOA at the OHP 1.52m telescope on October
1997. Taking P Cyg and the reference star 59 Cyg AO long exposures we find that
P Cyg clearly exhibits a large and diffuse intensity distribution compared to
the 59 Cyg's point-like source. A deconvolution of P Cyg using 59 Cyg as the
Point Spread Function was performed by means of the Richardson-Lucy algorithm.
P Cyg clearly appears as an unresolved star surrounded by a clumped envelope.
The reconstructed image of P Cyg is compared to similar spatial resolution maps
obtained from radio aperture synthesis imaging. We put independent constraints
on the physics of P Cyg which agree well with radio results. We discuss future
possibilities to constrain the wind structure of P Cyg by using
multi-resolution imaging, coronagraphy and long baseline interferometry to
trace back its evolutionary status.Comment: 10 pages, 19 Encapsulated Postscript figure
Forecasting machine performance check output using Holt-Winters approach
Background: Machine Performance Check (MPC) is an automated TrueBeam quality control (QC) tool used to verify beam output, isocenter, and uniformity. The aim of this study was to build an MPC output variation time series modeled on the Holt-Winters method over thirty days.
Methods: After AAPM TG-51 and baseline data were established for the Edge TrueBeam, daily MPC output data were gathered and analyzed through a Holt-Winters (additive and multiplicative) method. The model's performance was assessed via three standard error measures: the mean squared error (MSE), the mean absolute percentage error (MAPE), and the mean absolute deviation (MAE). The aim was achieved using a nonlinear multistart solver on the Excel platform.
Results: The results showed that MPC output variation forecasting is energy and model dependent. Both additive and multiplicative Holt-Winters methods were suitable for the analysis. The performance metrics MSE, MAPE, and MAD were found to be well within acceptable limits.
Conclusions: A Holt-Winters model was able to accurately forecast the MPC output variation
Statistical process control: machine performance check output variation
Background: The aim of this study was to illustrate and evaluate the use of different statistical process control (SPC) aspects to examine linear accelerator daily output variation through machine performance check (MPC) over a month.
Methods: MPC daily output data were obtained over a month after AAPM TG-51 were performed. Baseline data were set, and subsequent data were conducted through SPC. The Shewhart chart was used to determine the upper and lower control limits, whereas CUSUM for subtle changes.
Results: The upper and lower control limits obtained via SPC analysis of the MPC data were found to fall within AAPM Task Group 142 guidelines. MPC output variation data were within ±3% of their action limits values and were within 1% over thirty days of data. The process capability ratio and process acceptability ratio, Cp and Cpk values were ≥2 for all energies. Potential undetected deviations were captured by the CUSUM chart for photons and electrons beam energy.
Conclusions: Control charts were found to be useful in terms of detecting changes in MPC output
Taxonomy of mayapple rust: the genus Allodus resurrected
Mayapple rust is a common, disfiguring disease that is widespread in temperate eastern North America wherever the host, Podophyllum peltatum, occurs. Puccinia podophylli, the etiological agent of this rust, has been shown to be distantly related to both Puccinia and Uromyces as exemplified by their types. A systematic study was made to determine the generic classification of P. podophylli. Phylogenetic analyses of two rDNA loci from multiple specimens support the recognition of this taxon as a separate genus of Pucciniaceae. Based on historical literature and type material, P. podophylli was found to represent the type of the forgotten genus Allodus and it is correctly named Allodus podophylli. A neotype is designated for Puccinia podophylli Schwein. (; Allodus podophylli) and a lectotype is designated for Aecidium podophylli
Gamma Putty shielding effect in megavoltage photon beam
Purpose: Traditionally, lead and Cerrobend have been employed for field shaping in radiation therapy. Lately, another shielding material called Gamma Putty has emerged. The objective of this report is to examine its dosimetric and shielding characteristics in megavoltage photon beam.Methods: All measurements were carried out in a dual energy linac. Data were collected using a calibrated ionization chamber. Percent transmission, linear attenuation, and field size dependence were evaluated for open square fields (4 × 4 cm2 to 10 × 10 cm2) defined by collimator jaws and for different Gamma Putty thicknesses (t = 0, 0.3, 0.5, 1.0, 1.5, 2.0, and 2.5 cm) at 6 and 18 MV photon beams. The measurements were performed both in air using appropriate acrylic buildup cap and in solid water.Results: The Gamma Putty tray factor (GPTF) increased steadily with field size for both 6 and 18 MV. It was characterized by a half value thickness (HVT) of 2.513 ± 0.101 and 2.855 ± 0.024 cm for 6 and 18 MV, respectively. The reduction in surface dose was about 6%, 14.5%, 22%, 36.37%, and 54% for 6 MV and 2.75 %, 9.36 %, 16.25 %, 28.95 %, and 44.47 % for 18 MV for Gamma Putty thicknesses of 0.3, 0.5, 1.0, 1.5, 2.0, and 2.5 cm.Conclusion: The result of Gamma Putty shielding on the photon beam output increases with thickness, beam energy, and field size. Therefore, clinical use of Gamma Putty tray factors should be tailored for all thicknesses, beam energies, and field sizes.
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