38 research outputs found
Measurement of the forward-backward asymmetry in Î0b and ÎÂŻ0b baryon production in ppÂŻ collisions at sâ=1.96 TeV
We measure the forward-backward asymmetry in the production of Î0b and ÎÂŻ0b baryons as a function of rapidity in ppÂŻ collisions at sâ=1.96ââTeV using 10.4ââfbâ1 of data collected with the D0 detector at the Fermilab Tevatron collider. The asymmetry is determined by the preference of Î0b or ÎÂŻ0b particles to be produced in the direction of the beam protons or antiprotons, respectively. The measured asymmetry integrated over rapidity y in the range 0.1<|y|<2.0 is A=0.04±0.07(stat)±0.02(syst)
Grain Size, Misorientation, and Texture Evolution of Copper Processed by Equal Channel Angular Extrusion and the Validity of the HallâPetch Relationship
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Genetic alterations in signaling pathways that control cell-cycle progression, apoptosis, and cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-occurrence of alterations in these pathways differ between individual tumors and tumor types. Using mutations, copy-number changes, mRNA expression, gene fusions and DNA methylation in 9,125 tumors profiled by The Cancer Genome Atlas (TCGA), we analyzed the mechanisms and patterns of somatic alterations in ten canonical pathways: cell cycle, Hippo, Myc, Notch, Nrf2, PI-3-Kinase/Akt, RTK-RAS, TGFb signaling, p53 and beta-catenin/Wnt. We charted the detailed landscape of pathway alterations in 33 cancer types, stratified into 64 subtypes, and identified patterns of co-occurrence and mutual exclusivity. Eighty-nine percent of tumors had at least one driver alteration in these one alteration potentially targetable by currently available drugs. Thirty percent of tumors had multiple targetable alterations, indicating opportunities for combination therapy
Comparison of ether lipids found in archaeonbacterial thermophiles Pyrococcus furiousus, Methanopyrus kandleri, and methanothermus fervidus
Peer reviewed: YesNRC publication: Ye
In vitro assessment of archaeosome stability for oral delivery of vaccines
Peer reviewed: YesNRC publication: Ye
Enhanced stability of archaeosomes against attack by pancreatic lipase and bile salts
Peer reviewed: YesNRC publication: Ye
Scale up of a multi-functional solid oxide fuel cell to multi-tens of Kilowatt level (MF-SOFC)
A Comparative Analysis of Causes of Adolescent Delinquency: Focused on Patriarchy and Gender Difference
Spatial and temporal variation in elemental signatures of statoliths from the Patagonian longfin squid (Loligo gahi)
Author Posting. © National Research Council Canada, 2004. This article is posted here by permission of National Research Council Canada for personal use, not for redistribution. The definitive version was published in Canadian Journal of Fisheries and Aquatic Sciences 61 (2004): 1212-1224, doi:10.1139/F04-075.We quantified elemental signatures in statoliths of 718 Patagonian longfin squid (Loligo gahi) collected in the vicinity of the Falkland Islands (southwest Atlantic) and at sites on the Patagonian Shelf and coastal Peru. All squid were assigned to a spawning cohort by size, spawning condition, and back-calculated spawning date based on daily increments in statoliths. The remaining statolith was then analyzed for six elemental ratios (Mg/Ca, Mn/Ca, Sr/Ca, Cd/Ca, Ba/Ca, and Pb/Ca) using high-resolution inductively coupled plasma mass spectrometry (ICP-MS). Elemental concentrations in the statoliths were broadly similar to other biogenic aragonites. Differences in Sr/Ca ratios in statoliths among geographic locations were generally consistent with a negative correlation between Sr/Ca and temperature. Variations in statolith Cd/Ca and Ba/Ca values confirmed that during winter months, the squid were foraging deeper in the water column. Both Mg/Ca and Mn/Ca ratios in statoliths decreased with squid size, probably corresponding to a decrease in the contribution of the organic component of the statolith. Elemental signatures in the statoliths of L. gahi varied significantly geographically and between spring- and autumn-spawned cohorts, which must therefore have spent significant portions of their life histories in different environments.The research was funded by the Falkland Islands Government
and was also supported in part by National Science
Foundation grants OCE-9871047 and OCE-0134998 to
S.R.T