Uplift and subsidence associated with the great Aceh-Andaman earthquake of 2004

Rupture of the Sunda megathrust on 26 December 2004 produced broad regions of uplift and subsidence. We define the pivot line separating these regions as a first step in defining the lateral extent and the downdip limit of rupture during that great M_w ≈ 9.2 earthquake. In the region of the Andaman and Nicobar islands we rely exclusively on the interpretation of satellite imagery and a tidal model. At the southern limit of the great rupture we rely principally on field measurements of emerged coral microatolls. Uplift extends from the middle of Simeulue Island, Sumatra, at ~2.5°N, to Preparis Island, Myanmar (Burma), at ~14.9°N. Thus the rupture is ~1600 km long. The distance from the pivot line to the trench varies appreciably. The northern and western Andaman Islands rose, whereas the southern and eastern portion of the islands subsided. The Nicobar Islands and the west coast of Aceh province, Sumatra, subsided. Tilt at the southern end of the rupture is steep; the distance from 1.5 m of uplift to the pivot line is just 60 km. Our method of using satellite imagery to recognize changes in elevation relative to sea surface height and of using a tidal model to place quantitative bounds on coseismic uplift or subsidence is a novel approach that can be adapted to other forms of remote sensing and can be applied to other subduction zones in tropical regions

Biological Challenge Procedures Used to Study Co-occurring Nicotine Dependence and Panic Disorder

A wide array of biological challenge procedures – including carbon dioxide inhalation, hyperventilation, and breath holding – have been used to model panic in laboratory settings. Originally used to study developmental processes in panic disorder (PD), these procedures, along with nicotine patch administration and self-administered smoking, have recently been applied to help understand the etiology of co-occurring nicotine dependence and PD. The goals of the present paper are to review studies that have employed biological challenges to study the comorbid condition, identify the advantages and limitations of the various procedures, describe desirable outcome measures for use in biological challenges, and present recommendations for future challenge studies in this field. We argue that biological challenges, though in need of standardization, are useful for studying the development, maintenance, prevention, and treatment of comorbid nicotine dependence and PD

Changing Groundwater Levels in the Sandstone Aquifers of Northern Illinois and Southern Wisconsin: Impacts on Available Water Supply

In 2014-15, the Illinois State Water Survey conducted their largest synoptic measurement of water levels (i.e., heads) in Cambrian-Ordovician sandstone wells since 1980. The study covered 33 counties in the northern half of Illinois where demands for water are satisfied, in part, by sandstone aquifers. The Wisconsin Geological and Natural History Survey also measured sandstone wells in 10 counties in southern Wisconsin. These observations were used to generate head contours of the sandstone aquifers. These contours provide insight into the direction and magnitude of groundwater flow. They also can be compared with historic measurements, providing insight into the impact of changing groundwater withdrawals through time. In predevelopment conditions, heads in the Cambrian-Ordovician sandstone aquifers were near or above land surface. Due to pumping from the sandstone aquifers, heads have decreased over time; this decrease is referred to as drawdown. In 2014, drawdown in northeastern Illinois was typically over 300 ft and exceeded 800 ft in the Joliet region. Three factors drove this large drawdown. First, demands for water from sandstone aquifers are much greater in northeastern Illinois than in the rest of the study region. Second, the sandstone aquifers are overlain by aquitards, which are low permeable materials that limit vertical infiltration of water. Third, the Sandwich Fault Zone limits water flowing into the sandstone aquifers of northeastern Illinois from the south. Heads near the center of the cone of depression continue to have a decreasing trend. The more severe drawdown in northeastern Illinois has resulted in local areas where heads have fallen below the top of the sandstone, known as desaturation. Desaturation of a sandstone aquifer can create a number of water quality and quantity concerns. The uppermost sandstone, the St. Peter, was observed to be partially desaturated in portions of Will, Kane, and Kendall Counties under non-pumping conditions. Other areas in these counties are at risk of desaturation under pumping conditions or with the installation of additional wells connecting the St. Peter to deeper, more heavily stressed sandstones. Simulations from a groundwater flow model indicate that the risk of desaturation will increase with increased future withdrawals. Despite the relatively small demand for water throughout much of central Illinois, heads have been declining since predevelopment, likely due to the shale overlying the sandstone. This shale serves as an aquitard, minimizing vertical infiltration of groundwater to the sandstone. Sustained drawdown in this region could potentially induce flow from the southern half of the state, where water in the sandstone is highly saline and not suitable as a drinking water supply. Drawdown in northwestern Illinois was also typically small (<100 ft), primarily due to two factors: 1) low demands from the sandstone aquifers and 2) the absence of shale aquitards. The notable exception is in Winnebago County, near Rockford, where demands are historically high and drawdown was on the order of 100-200 ft. While the quantity of water in the aquifer is not a concern in this region, large withdrawals could result in reductions of natural groundwater discharge to surface waters, impacting stream ecosystems under low flow conditions. Drawdown since predevelopment was over 300 ft in southeastern Wisconsin, with the greatest drawdown in Waukesha County of over 400 ft. Recent trends indicate heads in the Waukesha area are recovering, although they are still well below predevelopment levels. [This report is also associated with the fact sheets: Changing Groundwater Levels in the Cambrian-Ordovician Sandstone Aquifers of Northern Illinois, 1980-2014, Groundwater Availability in Northeastern Illinois from Deep Sandstone Aquifers, and Sources of Water for Communities in Northeastern Illinois.published or submitted for publicationis peer reviewedOpe

Young Adult Smokers\u27 Neural Response to Graphic Cigarette Warning Labels

Introduction: The study examined young adult smokers\u27 neural response to graphic warning labels (GWLs) on cigarette packs using functional magnetic resonance imaging (fMRI). Methods: Nineteen young adult smokers (M age 22.9, 52.6% male, 68.4% non-white, M 4.3 cigarettes/day) completed pre-scan, self-report measures of demographics, cigarette smoking behavior, and nicotine dependence, and an fMRI scanning session. During the scanning session participants viewed cigarette pack images (total 64 stimuli, viewed 4 s each) that varied based on the warning label (graphic or visually occluded control) and pack branding (branded or plain packaging) in an event-related experimental design. Participants reported motivation to quit (MTQ) in response to each image using a push-button control. Whole-brain blood oxygenation level-dependent (BOLD) functional images were acquired during the task. Results: GWLs produced significantly greater self-reported MTQ than control warnings (p \u3c .001). Imaging data indicate stronger neural activation in response to GWLs than the control warnings at a cluster-corrected threshold p \u3c .001 in medial prefrontal cortex, amygdala, medial temporal lobe, and occipital cortex. There were no significant differences in response to warnings on branded versus plain cigarette packages. Conclusions: In this sample of young adult smokers, GWLs promoted neural activation in brain regions involved in cognitive and affective decision-making and memory formation and the effects of GWLs did not differ on branded or plain cigarette packaging. These findings complement other recent neuroimaging GWL studies conducted with older adult smokers and with adolescents by demonstrating similar patterns of neural activation in response to GWLs among young adult smokers

Urge to Gamble in Problem Gamblers Exposed to a Casino Environment

Cue-reactivity has received increased attention in addiction research, though not for gambling in particular. We examined cue reactivity in 18 problem gamblers by accompanying them to a gaming casino and measuring their subjective urge to gamble over a 1-h period. Half of the sample was additionally exposed to a gambling-specific negative mood induction (NMI) manipulation via guided imagery. Overall, about two-thirds of the sample reported moderate to high-gambling urges during the casino exposure. Additionally, the NMI reduced cue-reactivity. Finally, gambling urges in both groups decreased over the course of the exposure sessions. These findings suggest that a majority of problem gamblers experience the urge to gamble when exposed to gambling cues and that the intensity of these urges decrease with time, especially in the presence of a gambling-relevant NMI. Cue exposure should be studied further as a potential tool in the treatment of problem gambling

Pre-sorting and pen size effects on the stress responses at loading and unloading and transport losses in market weight pigs

Transport losses represent three challenges for the US swine industry and these are: 1) pig well-being, 2) increased rules and regulations, and 3) direct financial losses to producers and packers. Therefore; improving the well-being of pigs during transport and reducing the incidence of dead and non-ambulatory pigs is a priority for the US swine industry (NPB, 2007). Johnson et al. (2010) studied the effects of grow-finish pen size and manually pre-sorting pigs the day before loading on the stress responses at loading and unloading and transport losses in market weight pigs. The authors reported that pigs loaded from large pens (192 pigs/pen) that were pre-sorted from pen mates had 66% fewer dead and non-ambulatory pigs at the harvest facility compared to pigs loaded from small pens (32 pigs/pen) that were sorted from pen mates during loading. However, it is unclear if the reduction in transport losses was due to pen size and/or pre-sorting before marketing. Therefore, the objectives of the current two research trials were to 1) determine the effects of pre-sorting prior to loading on stress responses and transport losses at the harvest facility in the market weight pig; and 2) determine the effects of grow-finish pen size on stress responses and transport losses at the harvest facility in the market weight pig

Sudden acquired retinal degeneration syndrome (SARDS) â a review and proposed strategies toward a better understanding of pathogenesis, early diagnosis, and therapy

Sudden acquired retinal degeneration syndrome (SARDS) is one of the leading causes of currently incurable canine vision loss diagnosed by veterinary ophthalmologists. The disease is characterized by acute onset of blindness due to loss of photoreceptor function, extinguished electroretinogram with an initially normal appearing ocular fundus, and mydriatic pupils which are slowly responsive to bright white light, unresponsive to red, but responsive to blue light stimulation. In addition to blindness, the majority of affected dogs also show systemic abnormalities suggestive of hyperadrenocorticism, such as polyphagia with resulting obesity, polyuria, polydipsia, and a subclinical hepatopathy. The pathogenesis of SARDS is unknown, but neuroendocrine and autoimmune mechanisms have been suggested. Therapies that target these disease pathways have been proposed to reverse or prevent further vision loss in SARDSâ affected dogs, but these treatments are controversial. In November 2014, the American College of Veterinary Ophthalmologists' Vision for Animals Foundation organized and funded a Think Tank to review the current knowledge and recently proposed ideas about disease mechanisms and treatment of SARDS. These panel discussions resulted in recommendations for future research strategies toward a better understanding of pathogenesis, early diagnosis, and potential therapy for this condition.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/122446/1/vop12291.pd

Linkages between Cigarette Smoking Outcome Expectancies and Negative Emotional Vulnerability

The present investigation examined whether smoking outcome expectancies, as measured by the Smoking Consequences Questionnaire (SCQ; [Brandon, T.H., & Baker, T.B., (1991). The Smoking Consequences Questionnaire: The subjective expected utility of smoking in college students. Psychological Assessment, 3, 484–491.]), were incrementally related to emotional vulnerability factors among an adult sample of 202 daily cigarette smokers (44.6% women; Mage= 23.78 years, SD = 9.69 years). After controlling for cigarettes smoked/day, past 30-day marijuana use, current alcohol consumption, and coping style, negative reinforcement/negative affect reduction outcome expectancies were significantly associated with greater levels of negative affectivity, emotional dysregulation, and anxiety sensitivity. The observed effects for negative reinforcement/negative affect reduction also were independent of shared variance with other outcome expectancies. Negative personal consequences outcome expectancies were significantly and incrementally related to anxiety sensitivity, but not negative affectivity or emotional dysregulation. Findings are discussed in terms of the role of negative reinforcement/ negative affect reduction smoking outcome expectancies and clinically-relevant negative emotional vulnerability for better understanding cigarette smoking-negative mood problem