162 research outputs found
Business Models for Energy Entrepreneurship in Emerging Markets
Access to electricity produces greater levels of economic value and increases the quality of life in
emerging markets across the globe. Emerging economies have surpassed developed nations in
clean energy investment and deployment1
, but based on our review of the literature, there is a lack
of high-level study on the factors that most affect the success of these businesses. The goal of this
project is to identify these success factors, and use them to inform entrepreneurs’ strategic
decision-making as well as elucidate the environments in which these ventures have a higher
probability of success. By better understanding what drives success in the renewable energy
industry, both entrepreneurs and key stakeholders such as policy makers, investors, and interested
non-governmental organizations (NGOs) can better prioritize their efforts and investments to drive
increased levels of clean energy adoption.
This project focuses on clean energy business models in two emerging economies: India and
Uganda. These countries have significant differences in levels of access to energy and
development of their entrepreneurial landscapes, and therefore, provide a broad scope for analysis.
This report presents an overview of existing empirical research on factors that hinder or increase
success of business models, identifies potential gaps in this research, and presents analysis based
on qualitative, in-country interviews conducted by our team. Based on a comparative analysis
between the literature review and interview findings, the team drew conclusions about factors that
would benefit from better coordination and investment from industry players. The team also
identified aspects of the entrepreneurial experience in developing countries that are strong
candidates for further academic research.
Throughout the project, entrepreneurs and industry experts (such as the stakeholders above)
highlighted several of the key topics identified in existing research, including the challenge of
attracting private investment, strategies for revenue collection given limited ability to pay among
customers, the effect of domestic energy policy, and the industry’s lack of institutional support,
whether it be nonexistent or ineffective small business associations, trade associations, lobbying
groups, etc. While it was reassuring to see entrepreneur and stakeholder interviews validate what
had been uncovered in the literature review, the key value created by this project was largely the
nuance the interviews provided regarding the structural issues that were inhibiting growth for the
renewable and clean energy industries, and provide context around how some of these issues were
overcome in India and Uganda. Our research questions aimed to understand how entrepreneurs
can directly improve their prospects for success and where their efforts require coordination with
other partners in the renewable energy value chain or key policymakers.
The interviews revealed a clear distinction between the factors that entrepreneurs and industry
experts found to be most relevant and important to the success of clean energy entrepreneurs.
Factors such as positioning/strategy, company structure, ability to collect revenue, and business
model flexibility were by far more relevant for entrepreneurs than industry experts. This
understanding of which factors are more directly in entrepreneurs’ control can allow them to
prioritize which factors to focus their attention and resources on. In contrast, industry experts
regularly mentioned factors that were not top of mind for entrepreneurs in interviews such as
domestic energy policy, customer financial resources, and distribution and utility infrastructure.
Despite the relative dichotomy between entrepreneurs and industry experts, there was some
overlap among what factors the two groups found to be the most important. These factors include
talent attraction and retention, accessibility of private investment, competitive landscape,
consumer education and strategic partnerships. The overlapping factors indicate the significance
of these challenges, and highlights the potential areas where strategic partnerships would be the
most beneficial to foster a healthier entrepreneurial ecosystem.
Overall, the interviews raised new issues that were not discussed as in-depth in the literature. For
example, the conclusion that there is a lack of product awareness and trust among most consumers,
and that regulatory uncertainty of even the most well-intentioned policies can be extremely
detrimental. In India, there were difficulties retaining employees. In Uganda, there appears to be a
weak pipeline of educated, local talent. These issues demand comprehensive solutions that can
only be realized by greater cooperation and coordination between entrepreneurs, industry experts,
and policy makers. In sum, the hope is that this research will inform market players of key factors
of entrepreneurial success and act as a catalyst for future research. In particular, what factors do
entrepreneurs and industry experts see affecting success, where do they see greater opportunities
for coordination, and how are the Indian and Ugandan experiences representative of other
emerging markets?Master of ScienceSchool for Environment and SustainabilityUniversity of Michiganhttps://deepblue.lib.umich.edu/bitstream/2027.42/148815/1/Business Models for Energy Entrepreneurship in Emerging Markets_P46.pd
Aluminum Effects in Infants and Children
Aluminum has no known biological function; however, it is a contaminant present in most foods and medications. Aluminum is excreted by the renal system, and patients with renal diseases should avoid aluminum-containing medications. Studies demonstrating long-term toxicity from the aluminum content in parenteral nutrition components led the US Food and Drug Administration to implement rules for these solutions. Large-volume ingredients were required to reduce the aluminum concentration, and small-volume components were required to be labeled with the aluminum concentration. Despite these rules, the total aluminum concentration from some components continues to be above the recommended final concentration. The concerns about toxicity from the aluminum present in infant formulas and antiperspirants have not been substantiated but require more research. Aluminum is one of the most effective adjuvants used in vaccines, and a large number of studies have documented minimal adverse effects from this use. Long-term, high-concentration exposure to aluminum has been linked in meta-analyses with the development of Alzheimer disease
On Overreaching, or Why Rick Perry May Save the Voting Rights Act but Destroy Affirmative Action
Abstract The State of Texas is presently staking out two positions that are not typically pursued by a single litigant. On the one hand, Texas is seeking the invalidation of the Voting Rights Act, and, on the other, the State is now defending the validity of the expansive race-based affirmative action policy it uses at its flagship university. This Essay presses the claim that Texas has increased the chance it will lose in both Texas v. Holder and Fisher v. University of Texas because it has opted to stake out markedly extreme positions in each. I argue that Texas would be more likely to succeed had it chosen to temper both its actions and claims in the pending cases. As it stands, Texas's assertive stance in Fisher promises to bolster the aversion many Justices already feel towards affirmative action. With regard to the VRA, however, Texas's uncompromising approach to the regime may prove to be the VRA's best defense. As recent redistricting and voter ID decisions suggest, Texas's stance may be provide what is arguably better evidence for why the statute remains necessary than anything proffered by the VRA's many supporters. Indeed, the State's aggressively hostile stance towards the VRA has the potential to destabilize judicial misgivings about the statute, and, if not fully reverse them, postpone their implementation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98443/1/elj%2E2012%2E1147.pd
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Age Differences in the Associations Between Incarceration and Subsequent Substance Use, Sexual Risk-Taking, and Incident STI Among Black Sexual Minority Men and Black Transgender Women in the HIV Prevention Trials 061 Cohort
Incarceration can lead to different risk behaviors often due to increased distress and disruption of social networks. It is not well known, however, how these associations may differ by age. In this study, we measure age differences in longitudinal associations between incarceration and substance use, sex risk, and sexually transmitted infection (STI) among Black sexual minority men and Black transgender women (BSMM/BTW). We recruited BSMM/BTW from 2009 to 2011 that were part of the HIV Prevention Trials Network 061 study. We compared those less than 30 years old (n = 375) to those 30 years old or greater (n = 794) examining substance use, sex risk, and STI infection stratified by age. Logistic regression with inverse probability weighting was used for the statistical analysis. Approximately 59% of the sample reported incarceration history. In adjusted analysis, incarceration was more strongly associated with alcohol use and stimulant use among older individuals as was sexual risk behaviors including buying and selling sex. Concurrent partnerships were associated with the younger age groups. STI incidence was associated with younger individuals while associations with HIV infection were similar for the two age groups. Understanding differences in substance use and STI risk among age cohorts is imperative to the design and implementation of re-entry programs. Younger BSMM/BTW participating in re-entry support programs may benefit in particular from HIV/STI prevention and care efforts, while post-release substance abuse treatment and harm reduction programs should target older individuals with continued substance abuse
Antihyperlipidemic effects of Pleurotus ostreatus (oyster mushrooms) in HIV-infected individuals taking antiretroviral therapy
<p>Abstract</p> <p>Background</p> <p>Antiretroviral treatment (ART) regimens in HIV patients commonly cause significant lipid elevations, including increases in both triglycerides and cholesterol. Standard treatments for hypercholesterolemia include the HMG CoA reductase inhibitors, or "statins." Because many ART agents and statins share a common metabolic pathway that uses the cytochrome P450 enzyme system, coadministration of ART with statins could increase statin plasma levels significantly. The oyster mushroom, <it>Pleurotus ostreatus</it>, has been shown in animal models to decrease lipid levels - a finding that has been supported by preliminary data in a small human trial.</p> <p>Methods</p> <p>To assess the safety and efficacy of <it>P. ostreatus </it>in patients with HIV and ART-induced hyperlipidemia, a single-arm, open-label, proof-of-concept study of 8 weeks' duration with a target enrollment of 20 subjects was conducted. Study patients with ART-induced elevated non-HDL cholesterol levels (> 160 mg/dL) were enrolled. Participants received packets of freeze-dried <it>P. ostreatus </it>(15 gm/day) to be administered orally for the 8 week trial period. Lipid levels were drawn every two weeks to assess efficacy. Safety assessments included self-reported incidence of muscle aches and measurement of liver and muscle enzymes. Mean within-person change in lipid levels were estimated using generalized estimating equations to account for repeated observations on individuals. A 30 mg/dL decrease in non-HDL cholesterol was deemed clinically significant.</p> <p>Results</p> <p>126 patients were screened to enroll 25, of which 20 completed the 8-week study. The mean age was 46.4 years (36-60). Patients had a mean 13.7 yrs of HIV infection. Mean non-HDL cholesterol was 204.5 mg/dL at day 0 and 200.2 mg/dL at day 56 (mean within-person change = -1.70; 95% confidence interval (CI) = -17.4, 14.0). HDL cholesterol levels increased from 37.8 mg/dL at day 0 to 40.4 mg/dL on day 56 (mean within-person change = 2.6; 95% CI = -0.1, 5.2). Triglycerides dropped from 336.4 mg/dL on day 0 to 273.4 mg/dL on day 56 (mean within-person change = -63.0; 95% CI = -120.9, -5.1). Only 3 individuals achieved a sustained clinically significant (30 mg/dL) decline in non-HDL cholesterol after 8 weeks of therapy. There were no adverse experiences reported other than patients' distaste for the preparation. Liver function tests and muscle enzymes were not affected by the 8 weeks of treatment.</p> <p>Conclusions</p> <p><it>Pleurotus ostreatus </it>as administered in this experiment did not lower non-HDL cholesterol in HIV patients with ART-induced hypercholesterolemia. Small changes in HDL and triglycerides were not of a clinical magnitude to warrant further study.</p> <p>Trial Registration</p> <p>clinicaltrials.gov Identifier: <a href="http://www.clinicaltrials.gov/ct2/show/NCT00069524">NCT00069524</a></p
Technique of anterior colporrhaphy: a Dutch evaluation
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96395.pdf (publisher's version ) (Closed access)INTRODUCTION AND HYPOTHESIS: To evaluate the variation in techniques of anterior colporrhaphy among members of the Dutch Urogynecologic Society. METHODS: A questionnaire evaluating the technique of anterior colporrhaphy, preoperative and postoperative care, and use of the POP-Q score was sent out by e-mail. RESULTS: One hundred thirty-three completed questionnaires were received. The response rate was 65%. There are large variations in incisions, use of hydrodissection, method of plication, and excision of redundant vaginal epithelium. The urinary catheter was generally removed on day 2 after surgery and the vaginal pack on day 1. Less than half of the respondents used the POP-Q score routinely. CONCLUSIONS: Dutch gynecologists use a variety of surgical techniques to operate on a cystocele. This suggests that there is no widely accepted opinion on the best surgical approach. The lack of differentiation between central and lateral defects is striking and in contrast with the, mostly, American literature
Be prepared: communism and the politics of scouting in 1950s Britain
This article examines the exposure, and in some cases dismissal, of Boy Scouts who belonged or sympathised with the Young Communist League in Britain during the early 1950s. A focus on the rationale and repercussions of the organisation's approach and attitudes towards ‘Red Scouts’ found within their ‘ranks’ extends our understanding of youth movements and their often complex and conflicting ideological foundations. In particular, the post-World War Two period presented significant challenges to these spaces of youth work in terms of broader social and political change in Britain. An analysis of the politics of scouting in relation to Red Scouts questions not only the assertion that British McCarthyism was ‘silent’, but also brings young people firmly into focus as part of a more everyday politics of communism in British society
Satisfaction with dental care among patients who receive invasive or non-invasive treatment for non-cavitated early dental caries: findings from one region of the National Dental PBRN
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