Percutanous retrieval of internal double-j ureteral stents using a snare

Objective: In this paper, we aim to report our experience in percutaneous ureteral stent retrieval using a loop snare under fluoroscopic guidance and to assess the efficacy and safety of the method

Percutaneous antegrade ureteral stent placement: single center experience.

PURPOSEWe aimed to present our clinical experience with percutaneous antegrade ureteral stent placement in a single center.METHODSElectronic records of patients who underwent percutaneous image-guided ureteral stent placement between September 2005 and April 2017 were reviewed. A total of 461 patients (322 males, 139 females; age range, 19–94 years; mean age, 61.4±15 years) were included in the study. Patients were classified into two main groups: those with neoplastic disease and those with non-neoplastic disease. Failure was defined as persistence of high level of serum creatinine or an inability to place stents percutaneously. Postprocedural complications were grouped as percutaneous nephrostomy and stent placement related complications.RESULTSA total of 727 procedures in 461 patients were included in the study: 654 procedures (90%) in 407 patients (88.3%) were in the neoplastic group and 73 procedures (10%) in 54 patients (11.7%) were in the non-neoplastic group. Our technical success rates were 97.7% and 100% and complication rates were 3.1% and 4.1% in neoplastic and non-neoplastic groups, respectively. Seven stents retrievals and 112 balloon dilatations were performed successfully.CONCLUSIONPercutaneous antegrade ureteral stent placement is a safe and effective method for management of ureteral injuries and obstructions due to both malignant and benign causes when the retrograde approach has failed

Assessment of the Newborns Diagnosed with Phenylketonuria, Congenital Hypothyroidism and Biotinidase Deficiency by Newborn Screening Results in Adana in years 2010-2011

Amaç: Bu çalışmanın amacı Adana ilinde Halk Sağlığı Müdürlüğü tarafından yürütülen yenidoğan tarama programının 2010 ve 2011 yılı sonuçları incelenmesi ve ileri tetkiklerle kesin tanı konulan çocukların büyüme ve gelişmelerinin ve bunu etkileyen sosyodemografik faktörlerin değerlendirilmesidir.Gereç ve Yöntemler: 2010 ve 2011 yılında Adana ilinde doğan ve fenilketonüri (FKÜ), konjenital hipotiroidi (KH) ve biyotinidaz eksikliği (BE) tarama sonucunda tespit edilen çocuklar araştırmaya dâhil edildi. 2010 ve 2011 yıllarında 388 hipotiroidi, 7 biyotinidaz eksikliği ve 5 fenilketonüri tespit edilen toplam 400 çocuk çalışmamızın evrenini oluşturmuştur. Katılımcılara sosyodemografik özellikleri, büyüme ve gelişmeleri ile ilgili soruları içeren anket uygulandı.Bulgular: Adana ili 2010 yılı verilerine göre toplam 40.877 topuk kanı alınmış olup; insidansları hesaplandığında konjenital hipotiroidi 186 doğumda bir, Fenilketonüri 20.000 doğumda bir, biyotinidaz eksikliği 8.120 doğumda bir görülmüştür. 2011 yılında ise toplam 42.784 topuk kanı alınmış; insidansları hesaplandığında konjenital hipotiroidi 252 doğumda bir, Fenilketonüri 21.000 doğumda bir, biyotinidaz eksikliği ise 14.261 doğumda bir görülmüştür. Araştırma grubunda 322 (%80,5) kişiye ulaşılmıştır. Çalışmaya katılanların %39.7 (128)' si erkek, %60.3 (194)' ü ise kız idi. Çocukların gelişimleri ile ilgili sorulara baktığımızda, konjenital hipotiroidili çocukların %6'sının boyu %3 persentilin altında iken, kilosu %3 persentilin altında olanlar %10.5 idi. Fenilketonüri ve biyotidinaz eksikliği tanısı alanların ise hepsinin boyu ve kilosu %3 persentilin üzerinde idi.Tartışma: Yenidoğan tarama programı kapsamında olan fenilketonüri, biyotinidaz eksikliği, konjenital hipotiroidi tanısı alan çocuklar, erken tanı ve tedavi ile yaşıtlarıyla uyumlu bir şekilde yaşamlarına devam edebilirler. Ülkemizdeki insidanslarına baktığımızda her üç hastalığında diğer ülkere göre daha sık görüldüğü açıktır. Biz de çalışmamızda yenidoğan tarama programının önemini, olumlu sonuçlarını vurgulamak istedik.Objective: T he aim of this study is to examine the 2010 and 2011 results of the newborn screening program conducted by the Public Health Directorate in the province of Adana and to evaluate the growth and development of the children diagnosed with advanced examinations and the sociodemographic factors affecting them.Material and Methods: Children born in 2010 and 2011 in Adana were included in the screening of children diagnosed with phenylketonuria, congenital hypothyroidism and biotinidase deficiency. In 2010 and 2011, a total of 400 children with 388 hypothyroids, 7 biotinidase deficiencies and 5 phenylketonuria were identified. A questionnaire including questions about sociodemographic characteristics, growth and development of participant was applied.Results: A total of 40,877 heel blood were collected according to 2010 data; Congenital hypothyroidism was found at 186 births, Phenylketonuria at 20,000 births, and biotinidase at 8.120 births. In 2011, a total of 42.784 heel blood were taken; Congenital hypothyroidism was seen in 252 births, Phenylketonuria in 21.000 births, and biotinidase deficiency in 14.261 births. In the study group, 322 (80.5%) people were reached. 39.7% (128) of the participants were male and 60.3% (194) were female. When we look at the questions about the development of children, 6% of children with congenital hypothyroidism were 3% below the percentile, while those with a weight below 3% were 10.5%. In the field of diagnosis of phenylketonuria and biotinidase deficiency, the height and weight of all of them were above 3 percentile.Discussion: Children who are diagnosed with congenital hypothyroidism, phenylketonuria, biotinidase deficiency, congenital hypothyroidism, which are included in the newborn screening program, can continue their lives in accordance with their peers and early diagnosis and treatment. When we look at the incidence in our country, it is obvious that all three diseases are seen more frequently than the other countries. We also wanted to emphasize the importance and positive consequences of the newborn screening program in our study

Semi-synthetic biotin imprinting onto avidin crosslinked gold-silver nanoparticles

WOS:000305328900006This study is a different and new application of molecular imprinted polymers (MIPs) based on sensor technologies. In this study, semi-synthetic biotin imprinted polymeric shell has been decorated onto the surface of avidin crosslinked Au/Ag nanoclusters using bis (2-2'-bipyridyl) MATyr-MATrp-ruthenium(II) (MATyr-Ru-MATrp) as photosensitive monomer. The synthesized nanoclusters have been used the recognition of biotin by flourometric method. Synthesis of the photosensitive monomers has been realized by AmiNoAcid (monomer) Decorated and Light Underpinning Conjugation Approach (ANADOLUCA) method. This method provides a strategy for the preparation of photosensitive ruthenium based aminoacid monomers and oligomers, aminoacid monomer-protein crosslinking using photosensitation and conjugation approach on micro and nano-structures by ruthenium-chelate based monomers. The affinity constant (K-a) of biotin imprinted Au/Ag nanoclusters has been determined using the Scatchard method and found to be 3.89 x 10(5) M-1. The obtained calibration graph is linear for the range of 0.051 and 2.50 mu M of biotin. The detection limit of biotin has been found to be 15 nM. Also, the reusability of these nanoclusters has been investigated and it has been observed that the same clusters could be used 10 times during a long period without any binding capacity decreasing

Comparison of a Vessel Sealing System with a Conventional Technique in Hemorrhoidectomy

Objective: Milligan-Morgan, Park and Ferguson hemorrhoidectomy procedures are the ones most frequently used for the surgical treatment of hemorrhoidal disease. Attempts to modify these conventional approaches are made by using different techniques or tools to decrease blood loss, and reduce operating time and postoperative analgesic requirement. In this prospective randomized trial, the conventional Ferguson hemorrhoidectomy method is compared with the LigaSure® hemorrhoidectomy according to various criteria. Material and Methods: Forty patients who had grade 3-4 hemorrhoidal disease were randomly divided into two equal groups: the Ferguson Hemorrhoidectomy (n=20) and the LigaSure® hemorrhoidectomy (n=20). Operating time, demographic data, intraoperative and postoperative complications, postoperative pain, return of bowel movements and postoperative hospital stay were evaluated. The visual analogue score was used for the evaluation of pain on the first postoperative day. The patients have been followed up for at least 19 months. Results: The pain score, blood loss and operating time were significantly reduced in the LigaSure® hemorrhoidectomy group. Conclusion: LigaSure® hemorrhoidectomy is safe and feasible for the surgeon, and more comfortable than classical surgery for the patient