Understanding the ways and the dynamics of collaborative innovation processes: the case of the Maritime Cluster of the Algarve region (Portugal)

The Algarve region has always showed a close relationship with the sea as a result of its excellent natural conditions, historical and cultural reasons, and notorious know-how related with traditional maritime activities, such as fisheries and fish processing, and naval industry; more recently, nautical activities, such as tourism and recreational boating, have been gaining increased importance. The region is also well infrastructured in terms of public R&D institutions which are important cornerstones of the regional and national innovation systems. Through surveys carried out over a population of firms related to fisheries, aquaculture, fish processing and trade, nautical tourism, naval construction, and repair and shipping, we intend to: (1) characterize the innovation processes adopted by the Algarve’s firms of the maritime economy and evaluate some of the main outputs generated by R&D activities promoted by the regional innovation centers; (2) analyze the potential externalities linked to the production and dissemination of information from knowledge spillovers and knowledge networks; and (3) assess the strategic interest associated with the use of knowledge-intensive service activities regarding their role as sources and/or facilitators of innovation in customer organizations, or as carriers of innovation, when they help in transferring knowledge between or within organizations

Tourism, inclusive growth and decent work: a political economy critique

This paper interrogates the ideas of ‘sustained’ and ‘inclusive’ growth that are intrinsic to one of three UN Sustainable Development Goals (SDG 8 - Decent Work and Growth) adopted by the UN World Tourism Organisation’s (UNWTO) 2030 sustainable tourism agenda. It provides a Marxian-inspired political economy critique of the UNWTO’s embrace of SDG8 and highlights the blind spot within the UNWTO’s inclusive growth-led SDG agenda with respect to questions of equity and social justice. The paper contends that the UNWTO’s SDG-led agenda is contradicted by the logics of growth, competitiveness and profit-making that drive the continued expansion and development of tourism. Rather than addressing the structural injustices that entrench inequalities and reproduce exploitative labour practices, the notion of sustained and inclusive growth reinforces the primacy of capital and market notions of justice and continues to perpetuate a growth driven tourism development model. The paper contributes to a critical theorization of sustainable tourism and offers an informed critique of the current political agenda for sustainable tourism and its potential outcomes

Ultrasonic intensification as a tool for enhanced microbial biofuel yields

peer-reviewedUltrasonication has recently received attention as a novel bioprocessing tool for process intensification in many areas of downstream processing. Ultrasonic intensification (periodic ultrasonic treatment during the fermentation process) can result in a more effective homogenization of biomass and faster energy and mass transfer to biomass over short time periods which can result in enhanced microbial growth. Ultrasonic intensification can allow the rapid selective extraction of specific biomass components and can enhance product yields which can be of economic benefit. This review focuses on the role of ultrasonication in the extraction and yield enhancement of compounds from various microbial sources, specifically algal and cyanobacterial biomass with a focus on the production of biofuels. The operating principles associated with the process of ultrasonication and the influence of various operating conditions including ultrasonic frequency, power intensity, ultrasonic duration, reactor designs and kinetics applied for ultrasonic intensification are also described

Induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer: study protocol of a multicentre, open-label, parallel-arms, randomized controlled study (PelvEx II)

Background A resection with clear margins (R0 resection) is the most important prognostic factor in patients with locally recurrent rectal cancer (LRRC). However, this is achieved in only 60 per cent of patients. The aim of this study is to investigate whether the addition of induction chemotherapy to neoadjuvant chemo(re)irradiation improves the R0 resection rate in LRRC. Methods This multicentre, international, open-label, phase III, parallel-arms study will enrol 364 patients with resectable LRRC after previous partial or total mesorectal resection without synchronous distant metastases or recent chemo- and/or radiotherapy treatment. Patients will be randomized to receive either induction chemotherapy (three 3-week cycles of CAPOX (capecitabine, oxaliplatin), four 2-week cycles of FOLFOX (5-fluorouracil, leucovorin, oxaliplatin) or FOLFORI (5-fluorouracil, leucovorin, irinotecan)) followed by neoadjuvant chemoradiotherapy and surgery (experimental arm) or neoadjuvant chemoradiotherapy and surgery alone (control arm). Tumours will be restaged using MRI and, in the experimental arm, a further cycle of CAPOX or two cycles of FOLFOX/FOLFIRI will be administered before chemoradiotherapy in case of stable or responsive disease. The radiotherapy dose will be 25 × 2.0 Gy or 28 × 1.8 Gy in radiotherapy-naive patients, and 15 × 2.0 Gy in previously irradiated patients. The concomitant chemotherapy agent will be capecitabine administered twice daily at a dose of 825 mg/m2 on radiotherapy days. The primary endpoint of the study is the R0 resection rate. Secondary endpoints are long-term oncological outcomes, radiological and pathological response, toxicity, postoperative complications, costs, and quality of life. Discussion This trial protocol describes the PelvEx II study. PelvEx II, designed as a multicentre, open-label, phase III, parallel-arms study, is the first randomized study to compare induction chemotherapy followed by neoadjuvant chemo(re)irradiation and surgery with neoadjuvant chemo(re)irradiation and surgery alone in patients with locally recurrent rectal cancer, with the aim of improving the number of R0 resections

Postdischarge surveillance following cesarean section: The incidence of surgical site infection and associated factors

Background: The rate of surgical site infections (SSI) and their associated risk factors was identified by performing postdischarge surveillance following cesarean section at a public university teaching hospital in Brazil. Methods: The study was conducted at the Center for Women's Integrated Health Care in Brazil between May 2008 and March 2009. Women were contacted by telephone 15 and 30 days after cesarean section. During hospitalization, a form was completed on factors associated with post-cesarean SSI. The chi(2) test and Fisher exact test were used to analyze categorical variables and the Mann-Whitney test for numerical variables. Relative risks (RR) and their respective 95% confidence intervals (95% CI) were calculated for factors associated with SSI. P values < .05 were considered significant. Results: The final sample consisted of 187 women. SSI was detected in 44 cases (23.5%). In 42 of 44 women (95%), SSI appeared following discharge from hospital, becoming evident within the first 15 days following surgery. Number of prenatal consultations <= 7 (RR, 2.09; 95% CI: 1.26-3.48) and hypertension (RR, 2.07; 95% CI: 1.25-3.43) were significantly associated with SSI in the bivariate analysis. In the multivariate analysis, only hypertension (RR, 2.47; 95% CI: 1.21-5.04) remained significant. Conclusion: Postdischarge surveillance is essential for ensuring accurate estimates of post-cesarean section SSI. A 15-day postdischarge follow-up was shown to be sufficient. Hypertension was a factor associated with SSI.38646747

Phytosociologic associations and Natura 2000 habitats of Portuguese coastal sand dunes. Fitosociologia 44 suppl 1

Abstract The Portuguese coastline is quite long and the littoral ecosystems are of the outmost importance in the context of the national flora and vegetation. The diversity of vegetation types and the endemicity of their flora justify the attention paid to coastal habitats in the implementation of the Natura 2000 network. In this paper we present a synatoxonomical revision of the phanerophytic, chamaephytic and hemicryptophytic communities occurring in the sandy coastal areas of Portugal, together with their correspondence to the &quot;Natura 2000&quot; natural habitat types. The production of synthetic tables with all available relevés has allowed the segregation of plant community types. We also include maps concerning the distribution of all validated vegetation types occurring in the Portuguese sandy coastal areas. Key words: &quot;Natura 2000&quot; network, Portugal, psamophilous vegetation, sand dunes, syntaxonomy. Riassunto La costa portoghese è molto lunga e gli ecosistemi del litorale sono della massima importanza nel contesto della flora e della vegetazione nazionali. La diversità dei tipi di vegetazione e l&apos;endemicità della flora giustifica l&apos;attenzione che viene data agli habitat costieri nell&apos;attuazione della rete Natura 2000. In questo lavoro si presenta una revisione sinatossonomica delle comunità fanerofitiche, camefitiche e emicriptofitiche presenti nelle zone costiere sabbiose del Portogallo, insieme con la loro corrispondenza con i tipi di habitat naturali di &quot;Natura 2000&quot;. La produzione di tabelle di sintesi, con tutti i rilievi disponibili, ha consentito la segregazione dei tipi di comunità vegetali. Sono state inoltre allegate cartografie relative alla distribuzione di tutti i tipi di vegetazione convalidati che si rinvengono nel settore costiero sabbioso portoghese