Capacity building efforts and perceptions for wildlife surveillance to detect zoonotic pathogens: comparing stakeholder perspectives.

BackgroundThe capacity to conduct zoonotic pathogen surveillance in wildlife is critical for the recognition and identification of emerging health threats. The PREDICT project, a component of United States Agency for International Development's Emerging Pandemic Threats program, has introduced capacity building efforts to increase zoonotic pathogen surveillance in wildlife in global 'hot spot' regions where zoonotic disease emergence is likely to occur. Understanding priorities, challenges, and opportunities from the perspectives of the stakeholders is a key component of any successful capacity building program.MethodsA survey was administered to wildlife officials and to PREDICT-implementing in-country project scientists in 16 participating countries in order to identify similarities and differences in perspectives between the groups regarding capacity needs for zoonotic pathogen surveillance in wildlife.ResultsBoth stakeholder groups identified some human-animal interfaces (i.e. areas of high contact between wildlife and humans with the potential risk for disease transmission), such as hunting and markets, as important for ongoing targeting of wildlife surveillance. Similarly, findings regarding challenges across stakeholder groups showed some agreement in that a lack of sustainable funding across regions was the greatest challenge for conducting wildlife surveillance for zoonotic pathogens (wildlife officials: 96% and project scientists: 81%). However, the opportunity for improving zoonotic pathogen surveillance capacity identified most frequently by wildlife officials as important was increasing communication or coordination among agencies, sectors, or regions (100% of wildlife officials), whereas the most frequent opportunities identified as important by project scientists were increasing human capacity, increasing laboratory capacity, and the growing interest or awareness regarding wildlife disease or surveillance programs (all identified by 69% of project scientists).ConclusionsA One Health approach to capacity building applied at local and global scales will have the greatest impact on improving zoonotic pathogen surveillance in wildlife. This approach will involve increasing communication and cooperation across ministries and sectors so that experts and stakeholders work together to identify and mitigate surveillance gaps. Over time, this transdisciplinary approach to capacity building will help overcome existing challenges and promote efficient targeting of high risk interfaces for zoonotic pathogen transmission

Prospective investigation of complementary and alternative medicine use and subsequent hospitalizations

<p>Abstract</p> <p>Background</p> <p>The prevalence of complementary and alternative medicine (CAM) use has been estimated to be as high as 65% in some populations. However, there has been little objective research into the possible risks or benefits of unmanaged CAM therapies.</p> <p>Methods</p> <p>In this prospective study of active duty US Navy and Marine Corps personnel, the association between self-reported practitioner-assisted or self-administered CAM use and future hospitalization was investigated. Cox regression models were used to examine risk of hospitalization due to any cause over the follow-up period from date of questionnaire submission, until hospitalization, separation from the military, or end of observation period (June 30, 2004), whichever occurred first.</p> <p>Results</p> <p>After adjusting for baseline health, baseline trust and satisfaction with conventional medicine, and demographic characteristics, those who reported self-administering two or more CAM therapies were significantly less likely to be hospitalized for any cause when compared with those who did not self-administer CAM (HR = 0.38; 95% CI = 0.17, 0.86). Use of multiple practitioner-assisted CAM was not associated with a significant decrease or increase of risk for future hospitalization (HR = 1.86; 95 percent confidence interval = 0.96-3.63).</p> <p>Conclusion</p> <p>While there were limitations to these analyses, this investigation utilized an objective measure of health to investigate the potential health effects of CAM therapies and found a modest reduction in the overall risk of hospitalization associated with self-administration of two or more CAM therapies. In contrast, use of practitioner-assisted CAM was not associated with a protective effect.</p

Absolute magnitudes for late-type dwarf stars for Sloan photometry

We present a new formula for absolute magnitude determination for late-type dwarf stars as a function of (g-r) and (r-i) for Sloan photometry. The absolute magnitudes estimated by this approach are brighter than those estimated by colour-magnitude diagrams, and they reduce the luminosity function rather close to the luminosity function of Hipparcos.Comment: 11 pages, 9 figures and 5 tables, accepted for publication in A

The effect of inserting an inter-stimulus interval in face-voice matching tasks

Voices and static faces can be matched for identity above chance level. No previous face- voice matching experiments have included an inter-stimulus interval (ISI) exceeding 1 second. We tested whether accurate identity decisions rely on high-quality perceptual representations temporarily stored in sensory memory, and therefore whether the ability to make accurate matching decisions diminishes as the ISI increases. In each trial, participants had to decide whether an unfamiliar face and voice belonged to the same person. The face and voice stimuli were presented simultaneously in Experiment 1, there was a 5 second ISI in Experiment 2, and a 10 second interval in Experiment 3. The results, analysed using multilevel modelling, revealed that static face-voice matching was significantly above chance level only when the stimuli were presented simultaneously (Experiment 1). The overall bias to respond same identity weakened as the interval increased, suggesting that this bias is explained by temporal contiguity. Taken together, the findings highlight that face-voice matching performance is reliant on comparing fast-decaying, high-quality perceptual representations. The results are discussed in terms of social functioning

New absolute magnitude calibrations for W Ursa Majoris type binaries

Parallaxes of W UMa stars in the Hipparcos catalogue have been analyzed. 31 W UMa stars, which have the most accurate parallaxes ($\sigma_{\pi}/\pi<0.15$) which are neither associated with a photometric tertiary nor with evidence of a visual companion, were selected for re-calibrating the Period--Luminosity--Color (PLC) relation of W UMa stars. Using the Lutz--Kelker (LK) bias corrected (most probable) parallaxes, periods ($0.26< P(day)< 0.87$), and colors (0.04<$(B-V)_{0}$<1.28) of the 31 selected W UMa, the PLC relation have been revised and re-calibrated. The difference between the old (revised but not bias corrected) and the new (LK bias corrected) relations are almost negligible in predicting the distances of W UMa stars up to about 100 parsecs. But, it increases and may become intolerable as distances of stars increase. Additionally, using $(J-H)_{0}$ and $(H-K_{s})_{0}$ colors from 2MASS (Two Micron All Sky Survey) data, a PLC relation working with infrared data was derived. It can be used with infrared colors in the range $-0.01<(J-H)_{0}<0.58$, and $-0.10<(H-K_{s})_{0}<0.18$. Despite {\em 2MASS} data are single epoch observations, which are not guaranteed at maximum brightness of the W UMa stars, the established relation has been found surprisingly consistent and reliable in predicting LK corrected distances of W UMa stars.Comment: 9 pages, 8 figures and 2 tables, accepted for publication in Astronomische Nachrichte

Outsider Positions: Negotiating Gender, Nationality and Memory in the War Writing of Enid Bagnold

In 1918 Enid Bagnold published A Diary Without Dates, a revealing book that kept few secrets about life in the wartime hospital. Bagnold’s book has helped the construction of the mythology of disillusionment that has clouded memory of the war for a century. In 1920, Bagnold published The Happy Foreigner, a novel that is much less easy to categorize. As her protagonist, Fanny, drives across the derelict battlefields of France, she reflects on the ways in which those battlefields may be recalled in later cultural memory. However, there is a curious optimism in Fanny that is quite at odds with these later constructions of disillusionment. France in 1919 is a melting pot of different people, military and civilian, men and women, representing many different nations as the first understandings of memory crystallize. This essay explores Enid Bagnold’s two war books in terms of the ways in which she negotiates gender and nationality. What does it mean to be a woman in a hospital? How do different nationalities interact in the post-war landscape, questioning these myths of disillusionment before they are even constructed? By considering these outsider positions, I shall argue that Bagnold’s role in helping to shape our memory of the war is far more complex than it might first appear

Seasonal movements and habitat use of African buffalo in Ruaha National Park, Tanzania.

BACKGROUND:Assessing wildlife movements and habitat use is important for species conservation and management and can be informative for understanding population dynamics. The African buffalo (Syncerus caffer) population of Ruaha National Park, Tanzania has been declining, and little was known about the movement, habitat selection, and space use of the population, which is important for understanding possible reasons behind the decline. A total of 12 African buffalo cows from four different herds were collared with satellite transmitters. Movements were assessed over 2 years from 11 animals. RESULTS:The space use of the individual collared buffaloes as an approximation of the 95% home range size estimated using Brownian bridge models, ranged from 73 to 601 km2. The estimated home ranges were larger in the wet season than in the dry season. With the exception of one buffalo all collared animals completed a wet season migration of varying distances. A consistent pattern of seasonal movement was observed with one herd, whereas the other herds did not behave the same way in the two wet seasons that they were tracked. Herd splitting and herd switching occurred on multiple occasions. Buffaloes strongly associated with habitats near the Great Ruaha River in the dry season and had little association to permanent water sources in the wet season. Daily movements averaged 4.6 km (standard deviation, SD = 2.6 km), with the longest distances traveled during November (mean 6.9 km, SD = 3.6 km) at the end of the dry season and beginning of the wet season. The shortest daily distances traveled occurred in the wet season in April-June (mean 3.6 km, SD = 1.6-1.8 km). CONCLUSION:The Great Ruaha River has experienced significant drying in the last decades due to water diversions upstream, which likely has reduced the suitable range for buffaloes. The loss of dry season habitat due to water scarcity has likely contributed to the population decline of the Ruaha buffaloes

ZOOM or Non-ZOOM? Assessing spinal cord diffusion tensor imaging protocols for multi-centre studies

The purpose of this study was to develop and evaluate two spinal cord (SC) diffusion tensor imaging (DTI) protocols, implemented at multiple sites (using scanners from two different manufacturers), one available on any clinical scanner, and one using more advanced options currently available in the research setting, and to use an automated processing method for unbiased quantification. DTI parameters are sensitive to changes in the diseased SC. However, imaging the cord can be technically challenging due to various factors including its small size, patient-related and physiological motion, and field inhomogeneities. Rapid acquisition sequences such as Echo Planar Imaging (EPI) are desirable but may suffer from image distortions. We present a multi-centre comparison of two acquisition protocols implemented on scanners from two different vendors (Siemens and Philips), one using a reduced field-of-view (rFOV) EPI sequence, and one only using options available on standard clinical scanners such as outer volume suppression (OVS). Automatic analysis was performed with the Spinal Cord Toolbox for unbiased and reproducible quantification of DTI metrics in the white matter. Images acquired using the rFOV sequence appear less distorted than those acquired using OVS alone. SC DTI parameter values obtained using both sequences at all sites were consistent with previous measurements made at 3T. For the same scanner manufacturer, DTI parameter inter-site SDs were smaller for the rFOV sequence compared to the OVS sequence. The higher inter-site reproducibility (for the same manufacturer and acquisition details, i.e. ZOOM data acquired at the two Philips sites) of rFOV compared to the OVS sequence supports the idea that making research options such as rFOV more widely available would improve accuracy of measurements obtained in multi-centre clinical trials. Future multi-centre studies should also aim to match the rFOV technique and signal-to-noise ratios in all sequences from different manufacturers/sites in order to avoid any bias in measured DTI parameters and ensure similar sensitivity to pathological changes