2,123 research outputs found
Space shuttle: Aerodynamic heating to the Grumman space shuttle orbiters (ROS-NB1 and ROS-WB1) at Mach number 8.0
Hypersonic wind tunnel test of two delta wing orbiter model
A novel scheme to detect optical DPSK signals
We propose and demonstrate a novel approach to
detect optical differential phase-shift keying signals. The technique is based on differential phase-to-polarization conversion in a polarization-maintaining fiber, so that the polarization-modulated signal can be detected by using a polarizer and a common intensity modulation receiver
39-K Bose-Einstein condensate with tunable interactions
We produce a Bose-Einstein condensate of 39-K atoms. Condensation of this
species with naturally small and negative scattering length is achieved by a
combination of sympathetic cooling with 87-Rb and direct evaporation,
exploiting the magnetic tuning of both inter- and intra-species interactions at
Feshbach resonances. We explore tunability of the self-interactions by studying
the expansion and the stability of the condensate. We find that a 39-K
condensate is interesting for future experiments requiring a weakly interacting
Bose gas.Comment: 5 page
Feshbach resonances in ultracold K(39)
We discover several magnetic Feshbach resonances in collisions of ultracold
K(39) atoms, by studying atom losses and molecule formation. Accurate
determination of the magnetic-field resonance locations allows us to optimize a
quantum collision model for potassium isotopes. We employ the model to predict
the magnetic-field dependence of scattering lengths and of near-threshold
molecular levels. Our findings will be useful to plan future experiments on
ultracold potassium atoms and molecules.Comment: 7 pages, 6 figure
Fish oil-based emulsion for the treatment of parenteral nutrition associated liver disease in an adult patient
Background & aims: Reversal of parenteral nutrition associated liver disease with fish oil emulsion (FO) has been reported in infants. We report a similar case in an adult patient. Methods: A 58 year-old female on home parenteral nutrition for a short bowel syndrome due to Crohn's disease, showed a progressive worsening of liver steatosis, and a persistent increase of the plasma liver function tests (LFTs). LFTs, serum alpha-tochopherol, red blood cell membrane fatty acids and liver histology were evaluated before and after an 8 month treatment with FO. Results: The patient's LFT's improved. There was an increase of the n-3 and a decrease of the n-6 series of fatty acids in erythrocyte membrane. There was an approximate 30% increase in vitamin E status. Before FO, liver histology showed a non-alcoholic steatohepatitis with grade 2 steatosis and inflammation and stage 3 fibrosis. After the treatment, steatosis and inflammation were grade 1, whereas fibrosis remained at stage 3. Conclusions: Infusion of FO was associated with consistent changes of cell membrane fatty acid structure and with mild improvement of vitamin E status. A potential role of FO in decreasing liver steatosis and inflammation with no change of liver fibrosis might be suggested. © 2010 European Society for Clinical Nutrition and Metabolism
Physicochemical properties of mixed micellar aggregates containing CCK peptides and Gd complexes designed as tumor specific contrast agents in MRI
New amphiphilic molecules containing a bioactive peptide or a claw moiety have been prepared
in order to obtain mixed micelles as target-specific contrast agents in magnetic resonance imaging. The
first molecule, C18H37CONH(AdOO)2-G-CCK8 (C18CCK8), contains a C18 hydrophobic moiety bound to
the C-terminal cholecystokinin octapeptide amide (CCK 26-33 or CCK8). The second amphiphilic
compound, C18H37CONHLys(DTPAGlu)CONH2 (C18DTPAGlu) or its gadolinium complex, (C18DTPAGlu-
(Gd)), contains the same C18 hydrophobic moiety bound, through a lysine residue, to the DTPAGlu chelating
agent. The mixed aggregates as well as the pure C18DTPAGlu aggregate, in the presence and absence
of Gd, have been fully characterized by surface tension measurements, FT-PGSE-NMR, fluorescence
quenching, and small-angle neutron scattering measurements. The structural characterization of the mixed
aggregates C18DTPAGlu(Gd)-C18CCK8 indicates a spherical arrangement of the micelles with an external
shell of 21 Ã… and an inner core of 20 Ã…. Both the DTPAGlu(Gd) complexes and the CCK8 peptides
point toward the external surface. The measured values for relaxivity in saline medium at 20 MHz proton
Larmor frequency and 25 °C are 18.7 mM-1 s-1. These values show a large enhancement in comparison
with the isolated DTPAGlu(Gd) complex
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