Simulation of heat transfer to kaolin slurry which exhibits enhanced damping of turbulence

Paper presented to the 10th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Florida, 14-16 July 2014.The paper deals with simulation of mass and heat transfer of Kaolin slurry with a yield stress. The yield stress is caused mainly by very fine solid particles which are of non-settling type. Slurries with the yield stress appear frequently in chemical engineering, biotechnology, medicine, power and paper plants, food and mining industries and are often strongly influenced by heat exchange between the transported materials and the surroundings. The paper is focused on heat transfer in hydro-dynamically and thermally developed turbulent pipe flow of Kaolin slurry. The slurry contains solid particles with averaged diameter about 5 m, and concentration of solid phase which varies from 0% to 40% by volume. Experiments proved that such slurries exhibit enhanced damping of turbulence, so they require especially designed wall damping function. Simulation of slurry assumes that it is a single-phase flow with increased viscosity and density, and rheological properties can be described by Bingham model. The wall temperature and heat flux applied into the pipe wall are steady. The objective of the paper is to examine the influence of solids volume fraction on heat transfer by taking into account momentum and energy equations, and turbulence model with modified turbulence damping function. The effect of influential factors on the heat transfer between the pipe and the slurry were analyzed. The paper demonstrates substantial influence of solids volume fraction on velocity profile and as a consequence the temperature profile too. The results of numerical simulation demonstrate the importance of turbulence damping near a pipe wall. A possible cause of turbulence damping in the near-wall region is discussed.cf201

Risk of climate-induced damage in historical textiles

Eleven wool and silk historic textiles and two modern artist's canvases were examined to determine their water vapour adsorption, moisture dimensional response and tensile behaviour. All the textiles showed a similar general pattern of moisture response. A rise in ambient relative humidity (RH) from dry conditions produced expansion of a textile until a certain critical RH level after which a contraction occurred to a greater or lesser degree depending on the yarn crimp and the weave geometry. The largest expansion recorded between the dry state and 80% RH was 1.2 and 0.9% for wool and silk textiles, respectively. The largest shrinkage of 0.8% at high RH range was experienced by a modern linen canvas. Two potential damage mechanisms related to the moisture response of the textiles—stress building as a result of shrinkage of the textile restrained in its dimensional response and the fretting fatigue when yarns move with friction one against another—were found insignificant in typical textile display environments unless the textiles are severely degraded or excessively strained in their mounting

Pseudomonas aeruginosa partitioning protein ParB acts as a nucleoid-associated protein binding to multiple copies of a parS-related motif

ParA and ParB homologs are involved in accurate chromosome segregation in bacteria. ParBs participate in the separation of ori domains by binding to parS palindromes, mainly localized close to oriC. In Pseudomonas aeruginosa neither ParB deficiency nor modification of all 10 parSs is lethal. However, such mutants show not only defects in chromosome segregation but also growth retardation and motility dysfunctions. Moreover, a lack of parB alters expression of over 1000 genes, suggesting that ParB could interact with the chromosome outside its canonical parS targets. Here, we show that indeed ParB binds specifically to hundreds of sites in the genome. ChIP-seq analysis revealed 420 ParB-associated regions in wild-type strain and around 1000 in a ParB-overproducing strain and in various parS mutants. The vast majority of the ParB-enriched loci contained a heptanucleotide motif corresponding to one arm of the parS palindrome. All previously postulated parSs, except parS5, interacted with ParB in vivo. Whereas the ParB binding to the four parS sites closest to oriC, parS1-4, is involved in chromosome segregation, its genome-wide interactions with hundreds of parS half-sites could affect chromosome topology, compaction and gene expression, thus allowing P. aeruginosa ParB to be classified as a nucleoid-associated protein

Rules and Exceptions: The Role of Chromosomal ParB in DNA Segregation and Other Cellular Processes

Abstract: The segregation of newly replicated chromosomes in bacterial cells is a highly coordinated spatiotemporal process. In the majority of bacterial species, a tripartite ParAB-parS system, composed of an ATPase (ParA), a DNA-binding protein (ParB), and its target(s) parS sequence(s), facilitates the initial steps of chromosome partitioning. ParB nucleates around parS(s) located in the vicinity of newly replicated oriCs to form large nucleoprotein complexes, which are subsequently relocated by ParA to distal cellular compartments. In this review, we describe the role of ParB in various processes within bacterial cells, pointing out interspecies differences. We outline recent progress in understanding the ParB nucleoprotein complex formation and its role in DNA segregation, including ori positioning and anchoring, DNA condensation, and loading of the structural maintenance of chromosome (SMC) proteins. The auxiliary roles of ParBs in the control of chromosome replication initiation and cell division, as well as the regulation of gene expression, are discussed. Moreover, we catalog ParB interacting proteins. Overall, this work highlights how different bacterial species adapt the DNA partitioning ParAB-parS system to meet their specific requirements

State-independent quantum violation of noncontextuality in four dimensional space using five observables and two settings

Recently, a striking experimental demonstration [G. Kirchmair \emph{et al.}, Nature, \textbf{460}, 494(2009)] of the state-independent quantum mechanical violation of non-contextual realist models has been reported for any two-qubit state using suitable choices of \emph{nine} product observables and \emph{six} different measurement setups. In this report, a considerable simplification of such a demonstration is achieved by formulating a scheme that requires only \emph{five} product observables and \emph{two} different measurement setups. It is also pointed out that the relevant empirical data already available in the experiment by Kirchmair \emph{et al.} corroborate the violation of the NCR models in accordance with our proof

Prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery

The aim of the study was to analyze the prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery. Eyelashes from 73 patients selected for cataract surgery were evaluated at × 40 and × 100 magnification using light microscopy. The anterior segment was assessed with the slit lamp. Additionally, Schirmer I and break up time (BUT) tests were carried out before surgery and 1 and 3 months postoperatively. A specially designed questionnaire containing e.g. information about chronic skin and eye diseases, previous ophthalmic surgeries, and patient's hygiene habits was used to assess the demographic variables. A majority of patients were at the age of 70–79 years, and there were more females (83%) in the study group. Demodex folliculorum was found in 48% of the patients. There was a correlation between the number of parasites and the presence of blepharitis, discharge at eyelid margins, and conjunctival hyperemia. Schirmer I and BUT test results were lower in patients with Demodex infestation before and after cataract surgery. The higher number of mites was correlated with lower Schirmer I test results postoperatively. The presence of Demodex mites influences the conjunctiva and lid margins leading to inflammation. The higher number of Demodex mites disturbs the tear film over time after cataract surgery

Gamma-rays from binary system with energetic pulsar and Be star with aspherical wind: PSR B1259-63/SS2883

At least one massive binary system containing an energetic pulsar, PSR B1259-63/SS2883, has been recently detected in the TeV gamma-rays by the HESS telescopes. These gamma-rays are likely produced by particles accelerated in the vicinity of the pulsar and/or at the pulsar wind shock, in comptonization of soft radiation from the massive star. However, the process of gamma-ray production in such systems can be quite complicated due to the anisotropy of the radiation field, complex structure of the pulsar wind termination shock and possible absorption of produced gamma-rays which might initiate leptonic cascades. In this paper we consider in detail all these effects. We calculate the gamma-ray light curves and spectra for different geometries of the binary system PSR B1259-63/SS2883 and compare them with the TeV gamma-ray observations. We conclude that the leptonic IC model, which takes into account the complex structure of the pulsar wind shock due to the aspherical wind of the massive star, can explain the details of the observed gamma-ray light curve.Comment: 12 pages, 11 figures, accepted for publication in MNRA

Increased ParB level affects expression of stress response, adaptation and virulence operons and potentiates repression of promoters adjacent to the high affinity binding sites parS3 and parS4 in Pseudomonas aeruginosa

Similarly to its homologs in other bacteria, Pseudomonas aeruginosa partitioning protein ParB facilitates segregation of newly replicated chromosomes. Lack of ParB is not lethal but results in increased frequency of anucleate cells production, longer division time, cell elongation, altered colony morphology and defective swarming and swimming motility. Unlike in other bacteria, inactivation of parB leads to major changes of the transcriptome, suggesting that, directly or indirectly, ParB plays a role in regulation of gene expression in this organism. ParB overproduction affects growth rate, cell division and motility in a similar way as ParB deficiency. To identify primary ParB targets, here we analysed the impact of a slight increase in ParB level on P. aeruginosa transcriptome. ParB excess, which does not cause changes in growth rate and chromosome segregation, significantly alters the expression of 176 loci. Most notably, the mRNA level of genes adjacent to high affinity ParB binding sites parS1-4 close to oriC is reduced. Conversely, in cells lacking either parB or functional parS sequences the orfs adjacent to parS3 and parS4 are upregulated, indicating that direct ParB- parS3/ parS4 interactions repress the transcription in this region. In addition, increased ParB level brings about repression or activation of numerous genes including several transcriptional regulators involved in SOS response, virulence and adaptation. Overall, our data support the role of partitioning protein ParB as a transcriptional regulator in Pseudomonas aeruginosa

Pentagrams and paradoxes

Klyachko and coworkers consider an orthogonality graph in the form of a pentagram, and in this way derive a Kochen-Specker inequality for spin 1 systems. In some low-dimensional situations Hilbert spaces are naturally organised, by a magical choice of basis, into SO(N) orbits. Combining these ideas some very elegant results emerge. We give a careful discussion of the pentagram operator, and then show how the pentagram underlies a number of other quantum "paradoxes", such as that of Hardy.Comment: 14 pages, 4 figure