27,087 research outputs found

    ‘Holding onto trauma?’ The prevalence and predictors of PTSD, anxiety, and depression in police officers working with victims of child abuse, rape, and sexual exploitation

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    Research into post-traumatic stress disorder (PTSD) and other common mental disorders (CMDs) in police officers is limited, with the majority of research predominately conducted outside the UK, and no study quantitively examining the role of social support in relation to the mental health of UK police officers working with victims of trauma. Therefore, this study aimed to examine the prevalence and predictors of PTSD and CMD in UK police officers who investigate rape, sexual exploitation, and child abuse, along with the potential protective role of social support. Participants were police officers (n = 353) within one police area, who completed self-report measures of PTSD, anxiety, depression, and social support. Results showed that 23% of officers had potentially clinical levels of PTSD, 26% had moderate to severe levels of anxiety and 35% had moderate to severe levels of depression. Female officers, those of constable rank, those working with victims of child abuse, and those with lowest levels of social support had poorer mental health. There was tentative evidence that social support statistically moderated the relationship between tenure and depression. These findings suggest the need for bespoke help for the sub-group of officers experiencing mental health problems and for further research into the potential protective role of social support

    Surface disinfection challenges for Candida auris: an in-vitro study

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    The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment

    New approaches to object classification in synoptic sky surveys

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    Digital synoptic sky surveys pose several new object classification challenges. In surveys where real-time detection and classification of transient events is a science driver, there is a need for an effective elimination of instrument-related artifacts which can masquerade as transient sources in the detection pipeline, e.g., unremoved large cosmic rays, saturation trails, reflections, crosstalk artifacts, etc. We have implemented such an Artifact Filter, using a supervised neural network, for the real-time processing pipeline in the Palomar-Quest (PQ) survey. After the training phase, for each object it takes as input a set of measured morphological parameters and returns the probability of it being a real object. Despite the relatively low number of training cases for many kinds of artifacts, the overall artifact classification rate is around 90%, with no genuine transients misclassified during our real-time scans. Another question is how to assign an optimal star-galaxy classification in a multi-pass survey, where seeing and other conditions change between different epochs, potentially producing inconsistent classifications for the same object. We have implemented a star/galaxy multipass classifier that makes use of external and a priori knowledge to find the optimal classification from the individually derived ones. Both these techniques can be applied to other, similar surveys and data sets

    Hypocalcification and hypoplasia in permanent teeth of children from different ethnic groups in South Africa assessed with a new index

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    A new descriptive index, the HHI (hypocalcification-hypoplasia index), is described for comparing enamel defects in groups of people. The index was used in a study completed in 1986, in which 1251 11-year-old children from different ethnic groups resident in South Africa were examined: 210 rural black, 203 urban black, 206 urban colored, 426 urban Indian, and 206 urban white. The index can be used as a screening examination, and the results from these different ethnic groups are presented.TS2016.http://journals.sagepub.com/doi/abs/10.1177/08959374890030021001?journalCode=adr

    Biofilm formation is a risk factor for mortality in patients with Candida albicans bloodstream infection-Scotland, 2012-2013

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    Acknowledgements This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. Data collection was supported by a grant from Pfizer. G. Ramage was also supported by a research fellowship grant from Gilead Sciences. We are grateful to microbiology colleagues throughout Scotland for submitting isolates.Peer reviewedPublisher PD

    Midday measurements of leaf water potential and stomatal conductance are highly correlated with daily water use of Thompson Seedless grapevines

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    A study was conducted to determine the relationship between midday measurements of vine water status and daily water use of grapevines measured with a weighing lysimeter. Water applications to the vines were terminated on August 24th for 9 days and again on September 14th for 22 days. Daily water use of the vines in the lysimeter (ETLYS) was approximately 40 L vine−1 (5.3 mm) prior to turning the pump off, and it decreased to 22.3 L vine−1 by September 2nd. Pre-dawn leaf water potential (ιPD) and midday ιl on August 24th were −0.075 and −0.76 MPa, respectively, with midday ιl decreasing to −1.28 MPa on September 2nd. Leaf g s decreased from ~500 to ~200 mmol m−2 s−1 during the two dry-down periods. Midday measurements of g s and ιl were significantly correlated with one another (r = 0.96) and both with ETLYS/ETo (r = ~0.9). The decreases in ιl, g s, and ETLYS/ETo in this study were also a linear function of the decrease in volumetric soil water content. The results indicate that even modest water stress can greatly reduce grapevine water use and that short-term measures of vine water status taken at midday are a reflection of daily grapevine water us

    Examination of Combustion-Generated Smoke Particles from Biomass at Source: Relation to Atmospheric Light Absorption

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    The formation of carbonaceous aerosols from biomass combustion is associated with a high degree of uncertainty in global climate models. In this work, soot samples were generated from the combustion of pine wood, wheat straw and barley straw in a fixed bed stove; as well as from the combustion of biomass pyrolysis model compounds. Samples were collected on filters, which were used for the determination of Absorption Angstrom Exponent (AAE). In addition, the content and composition of elemental carbon (EC) and organic carbon (OC) were determined, and the interrelationships between these and the AAE were examined. It was found that the spectroscopic signature of samples with high ‘brown carbon’ emissions was comparable to that of many PAH and polyphenols, with AAE ranging from 1.0–1.2 for model compounds to 0.5–5.7 for biomass. In addition to the filter samples, particles were collected directly onto microscopy grids and analysed by transmission electron microscopy–electron energy loss spectroscopy (TEM-EELS) in order to determine structural characteristics. This was used to examine the impact of combustion conditions and flue gas dilution on particle structure. Smouldering phase and diluted particles were found to be less graphitic and twice as oxygenated as undiluted flaming phase particles. The results are interpreted to better understand the impact of combustion processes on soot formation from biomass combustion. Abbreviations: AAE: absorption angstrom exponent; ATN: light attenuation; AToFMS: aerosol time of flight mass spectrometer; BC: black carbon; BrC: brown carbon; C:O: carbon to oxygen ratio; CPD: cyclopentadienyl radical C5H5; DMS: differential mobility spectrometer; EC: elemental carbon; EELS: electron energy loss spectroscopy; HACA: hydrogen abstraction carbon addition; MCE: modified combustion efficiency; OA: organic aerosols; OC: organic carbon; PM: particulate matter; POM: primary (particulate)organic matter; Py-GC/MS: pyrolysis gas chromatography/mass spectrometry; sp2: amount of sp2 orbital hybridisation in atomic structure; SSA: single scattering albedo; TC: total carbon (BC+OC) or (EC+OC); TEM: transmission electron microscope; TGA: thermogravimetric analysis

    Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans

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    This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.This study tested the hypothesis that watermelon juice supplementation would improve nitric oxide bioavailability and exercise performance. Eight healthy recreationally-active adult males reported to the laboratory on two occasions for initial testing without dietary supplementation (control condition). Thereafter, participants were randomly assigned, in a cross-over experimental design, to receive 16 days of supplementation with 300 mL·day(-1) of a watermelon juice concentrate, which provided ∌3.4 g l-citrulline·day(-1) and an apple juice concentrate as a placebo. Participants reported to the laboratory on days 14 and 16 of supplementation to assess the effects of the interventions on blood pressure, plasma [l-citrulline], plasma [l-arginine], plasma [nitrite], muscle oxygenation and time-to-exhaustion during severe-intensity exercise. Compared to control and placebo, plasma [l-citrulline] (29 ± 4, 22 ± 6 and 101 ± 23 ΌM), [l-arginine] (74 ± 9, 67 ± 13 and 116 ± 9 ΌM) and [nitrite] (102 ± 29, 106 ± 21 and 201 ± 106 nM) were higher after watermelon juice supplementation (P < 0.01). However, systolic blood pressure was higher in the watermelon juice (130 ± 11) and placebo (131 ± 9) conditions compared to the control condition (124 ± 8 mmHg; P < 0.05). The skeletal muscle oxygenation index during moderate-intensity exercise was greater in the watermelon juice condition than the placebo and control conditions (P < 0.05), but time-to-exhaustion during the severe-intensity exercise test (control: 478 ± 80, placebo: 539 ± 108, watermelon juice: 550 ± 143 s) was not significantly different between conditions (P < 0.05). In conclusion, while watermelon juice supplementation increased baseline plasma [nitrite] and improved muscle oxygenation during moderate-intensity exercise, it increased resting blood pressure and did not improve time-to-exhaustion during severe-intensity exercise. These findings do not support the use of watermelon juice supplementation as a nutritional intervention to lower blood pressure or improve endurance exercise performance in healthy adults
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