A Study on GN ’Product Development Process Optimization Based on IPD

2013年中国发布的新交规开始施行后，给通信行业特别是蓝牙耳机行业的众多企业带来了市场契机。GN作为蓝牙耳机领域的领军企业，面对中国市场作为启动既是个良好的机会也是极大地挑战。然而作为公司核心的产品开发流程却表现出了很多的不适应性。不但没有帮助GN公司在国内复杂和激烈的竞争环境中脱颖而出，反而成为制约GN公司发展的瓶颈。 本论文针对GN公司目前流程存在的三个主要问题，即产品开发没有满足客户需求、新产品开发周期过长、没有进行合理的资源配置管理，运用集成产品开发（IPD）理论知识，围绕这三个问题分别展开流程优化。满足客户需求问题上提出规范客户需求导入流程。优化产品开发周期问题上主要是基于ASME...As all known in the year of 2013,new traffic regulation has officially put into force in China , undoubtedly, the new regulation has bring in lot of opportunity to enterprise especially to company which is Bluetooth headset producer. GN is most prominent leader among the company of Bluetooth headset, it would be great challenge and chance to GN in confront with initialing China Bluetooth market. N...学位：工商管理硕士院系专业：管理学院_工商管理硕士(MBA)学号：1792011115083

面板数据多指标聚类和变系数模型的方法与实证

文章通过将面板数据的多指标聚类分析和变系数模型相结合,分析了我国53个国家级开发区2003~2010年的经济运行情况。在聚类结果的基础上,通过建立面板模型总结了各类开发区经济运行的特点,找出了影响各类开发区经济运行的主要因素。结果表明这种结合是合理并且有效的。中央高校基本科研业务费专项资金资助项目(0140ZK1008

Application-Driven Big Data Mining

认为大数据挖掘的核心和本质是应用、数据、算法和平台4个要素的紧密结合。从大数据的特点出发,结合大数据挖掘的案例,提出大数据挖掘中的平台架构、数据获取和预处理、算法的选择和集成都是应用驱动的。强调大数据挖掘的目标来自实际应用的真实需求,只有结合具体应用数据和适合应用的算法,利用高效处理平台的支撑,并将挖掘到的模式或知识应用在实践中,才能体现大数据挖掘的真正价值。The core of big data analysis is the combination of applications, data,algorithms and platforms. Big data mining platforms, algorithms, and big data itself are driven by applications. Big data mining tasks come from real applications. With specific application data and appropriate algorithms, using efficient processing platform, digging into the patterns or knowledge in practice, big data mining platform can show its true value

网络基础设施中重要网元子图的确定

网元子图是指大规模网络基础设施中包含承载具体业务网元的拓扑子图,网元子图可用于网络基础设施运维中的故障排查、诊断与修复.首先定义重要网元的概念;其次,为确定重要网元子图,提出一个统一框架来度量网元在结构和业务两方面的影响力,将其作为重要网元的衡量标准,并设计了从重要网元扩展生成重要网元子图的高效算法.基于真实的网络基础设施数据以及合成的业务承载数据进行实验,实验结果验证了该方法可以高效地找到高质量的重要网元子图,并用于网络基础设施的运维,提高运维的效率,节省运维的成本.江苏省自然科学基金(BK20171447);;江苏省高等学校自然科学研究项目(17JKB520024);;2015年度教育部-中国移动科研基金项目(5-10);;南京邮电大学引进人才科研启动基金(NY215045

Study on the rheology of xanthan and synergistic interaction with konjac gum and other gum

研究前期筛选获得一株多糖胶质高产菌Xanthomonas axonopodis所产的黄原胶FJAT-10151-DTJZ的品质,为该黄原胶的开发应用提供基础数据及参考。通过分析浓度、剪切速率、p H、加热温度、时间、冻融处理等对FJAT-10151-DTJZ粘度的影响研究其流变性,并研究其与结冷胶、黄原胶、凝胶多糖、瓜尔豆胶、刺槐豆胶、魔芋胶、果胶和壳聚糖8种胶的协效性。实验结果表明,FJAT-10151-DTJZ溶液的粘度随浓度的升高而升高,且为非牛顿流体;当FJAT-10151-DTJZ的浓度为1%时,其粘度为343 m Pa·s;p H、冻融对FJAT-10151-DTJZ的粘度影响不大;FJAT-10151-DTJZ的最佳加热温度为75℃;粘度随加热时间先增大后减小,当加热温度为75℃,加热时间为150 min,1%浓度的FJAT-10151-DTJZ溶液的粘度为808 m Pa·s。FJAT-10151-DTJZ只与魔芋胶有强烈的协同增效作用,与壳聚糖、结冷胶、黄原胶、凝胶多糖、瓜尔豆胶、刺槐豆胶、果胶无协效性。A Xanthomonas axonopodis strain producing xanthan gum had been screened,and researched the quality of xanthan gum FJAT-10151-DTJZ in order to provide basic data and reference for development and application. The rheology properties of FJAT-10151-DTJZ were discussed according to the viscosity variation with different conditions including concentration,shearing,p H,heating temperature,heating time and freezingthawing. The synergistic interactions of FJAT-10151-DTJZ with chitosan,gellan gum,xanthan gum,curdlan,guar gum,locust bean gum and pectin were also investigated. The results showed that polysaccharide gum solution FJAT-10151-DTJZ was non-Newton fluid. It's viscosity rised with its concentration and reached to343 m Pa·s when the concentration was 1%. The p H change and freezing-thawing played negligible effects on its viscosity. Its viscosity was 808 m Pa·s when it was heated at 75 ℃ for 150 min. Besides,FJAT-10151-DTJZ had no synergistic interaction with chitosan,gellan gum,xanthan gum,curdlan,guar gum,locust bean gum and pectin except konjac gum.国家948项目(2014-Z48);; 福建省公益类科研院所专项(2015R1018-2);; 福建省农业科学院科技创新项目(2015CX-7

Effects of Initial p H Value for the Fermentation of Bacillus subtilis FJAT-14254 on the Generation of Metabolites Substances

为考察酸碱条件对枯草芽胞杆菌fJAT-14254代谢物产生的影响,采用气相色谱-质谱联用分析枯草芽胞杆菌fJAT-14254菌株的胞内成分。结果表明:通过谱库扫描得到32种高匹配率代谢物的初步鉴定结果,主要包括氨基酸类、酸类、烷烃类等,其中含量相对较高的有7种;枯草芽胞杆菌fJAT-14254代谢物的种类和含量与其培养环境的酸碱度变化呈一定的相关性,强酸性(P H=3)条件下培养的胞内代谢物具有特异性,而接近中性(P H=5、7)条件及碱性(P H=9、11)条件下培养胞内代谢物则相似。由此推断,不同P H条件影响发酵终点的P H,进而影响枯草芽胞杆菌fJAT-14254代谢物的产生。To study the relationship between p H of culture medium and intracellular metabolic of Bacillus subtilis FJAT-14254.Intracellular metabolites of B.subtilis FJAT-14254 were analyzed by GC-MS.564 metabolites were detected.31 metabolic markers including hexadecanoic acid, was obtained by data mining.The biochemical substances of B.subtilis FJAT-14254, produce in different p H conditions, had high specificity.The change of metabolites in different p H conditions was complex, not only linear relation.This research provided preliminary study of stress resistance of B.subtilis in metabolic level.公益性行业(农业)科研专项经费(No.201303094); 福建省农科院院青年创新基金(No.2013dqd-6); 福建省农科院杰出青年人才基金(No.2014JQ-2

戊型肝炎病毒衣壳蛋白特异性人源单克隆抗体的筛选与鉴定

目的:建立从外周血快速筛选戊型肝炎病毒(Hepatitis E virus,HEV)衣壳蛋白特异性人源抗体的方法,从疫苗免疫者外周血中筛选出相应抗体并进行鉴定。方法:采用分选型流式细胞仪获得外周血中HEV衣壳蛋白特异性的记忆B细胞,通过单细胞RT-PCR的方法获得抗体序列,并进行重组表达,最后对获得的人源单克隆抗体进行初步性质鉴定。结果:成功筛选到识别HEV衣壳蛋白的6株人源单克隆抗体,6株抗体均具有抗原结合活性,4株抗体具有中和活性。结论:成功获得HEV衣壳蛋白特异性人源单克隆抗体序列,并进行真核表达,对抗体的性质进行初步鉴定,为后期研究疫苗免疫的人体内的抗体演化打下基础。国家自然科学基金(No.81571996);;福建省自然科学基金(No.2016J05201)资

重组戊型肝炎病毒衣壳蛋白p239特异性吸附、侵入HepG2细胞并阻断野病毒对肝细胞的感染

By using Western blot and immunofluorescence assays,the recombinant HEV capsid protein p239 was found specifically attached to the HepG2 cell surface and entered to the cytoplasm with the increase of incubation temperature.Pre-mixture of wild-type HEV with p239 blocked the infectivity of the virus on primary cultured human hepatocytes and HepG2 cells,indicating that p239 and HEV competed the same targeting site on these cells.These data provide evidence that p239 has a similar cell surface structure with wild-type HEV