Comparative transcriptomics analysis between the fifth larvae and females of Angiostrongylus cantonensis and the expression pattern analysis of AC-14-3-3

广州管圆线虫（Angiostrongyluscantonensis）是一种非常重要的人畜共患病病原寄生虫，近年来已在更广的宿主和地理分布范围内发现了该寄生虫感染的存在。然而，在公共数据库中可获得的相关资源信息非常有限，这极大地限制了人们对该寄生虫在入侵宿主、寄生生活和免疫逃避等方面机制的深入研究，也严重影响了在该病诊断、治疗和抗虫疫苗研制等领域的发展。 广州管圆线虫第五期幼虫（L5）既是可以在人和小鼠等偶然宿主脑内长期存活并引起嗜酸性脑膜脑炎的时期，又是在天然宿主体内可以突破血脑屏障进入肺动脉的时期；此外，从L5到成虫阶段，尤其是L5到雌虫（F）的发育阶段中虫体增长速度非常快，体积增幅异常明...The rat lung worm, Angiostrongylus cantonensis, is an important zoonotic parasite which has been found in a wider hosts and geographical distribution than ever before in recent years. However, the available information in the public databases is indeed limited for deep researches on mechanisms of the host invasion, parasitism and immune escape, which also have greatly restricted the development of...学位：理学博士院系专业：生命科学学院_生物化学与分子生物学学号：2162013015414

Research on Application of CAN-BUS in Industrial Embedded Control System

CAN总线采用了ISO/OSI的7层参考模型中的3层：物理层、数据链路层和应用层。它是一个多主的串行通讯协议，能有效地支持具有很高安全等级的分布式实时控制。但是，协议在数据链路层只实现简单的冲突仲裁和重发机制，当CAN总线网络负载突发性增长时，存在通讯冲突问题，发送失败的报文在其尝试重发的过程中会严重影响到网络的运行稳定，造成其它报文的延迟。 在工业分布式嵌入式控制系统中，系统工艺要求达到的控制目标是由系统中各个CAN节点协调工作而实现的。CAN总线连接各节点，是控制信息和状态信息传递的通道。为了保证控制的实时性，本论文设计实现在应用层以时间片的方式来调度周期性报文的CAN总线应用协议，协调...CAN bus is subdivided into three different layers according to the ISO/OSI seven layers Reference Model: the Physical Layer, the Data Link Layer and the Application Layer.It is a multimaster serial communications protocol which efficiently supports distributed realtime control with a very high level of security.But the arbitration and retransmission mechanism in the Data Link Layer is simple,when ...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X200623008

A Study on Chaoguan System in Ming Dynasty (1429-1644): Focusing on Xushu Guan and Beixin Guan

本文以明代钞关制度和浒墅、北新两个具体钞关为研究对象，在充分的史料考实基础上，旨在从宏观和微观两个层面厘清其制度的具体内容，把握其制度内核，同时兼以探讨其与明代财政和商品经济发展之间的关系及其所起的影响和作用，以期能从一个侧面解析明代社会的财政和商品经济结构，加深对中国历史上榷关制度与经济体系之间互动关系的认识，为我国当前推进的财税制度改革提供一些历史性的思考。全文共分为五个部分： 第一章主要是介绍本文的研究对象，对本课题研究的学术史进行回顾，并简要地说明本文所运用的资料、理论和研究方法。 第二章主要是从明代商税的制度内容、钞关的制度本源、明初设置钞关的客观条件和主观动因等方面考察明代创制...Resting upon considerable historical materials research, this dissertation explores Chaoguan system in Ming dynasty by primarily focusing on two specific customs:Xushu Guan and Beixin Guan. It aims to illustrate the core principles of Chaoguan system through clarifying its contents both from macroscopic and microscopic perspectives, as well as the relationship between Chaoguan and the financial an...学位：历史学博士院系专业：人文学院历史学系_专门史学号：1022005140277

[[alternative]]Investigations of Liquid Crystal Materials

計畫編號：NSC93-2113-M032-006研究期間：200408~200507研究經費：615,000[[abstract]]合成含stilbene 官能基之條形,彎形,盤形,樹枝形,直角形分子,經由分子結構 之改變將致使分子由非液晶質變成各類型液晶質,藉以得到生成各類型液晶相 之幾何結構條件. 彎形分子之鐵電性及反鐵電性將以電場加以區分.新分子結 合液晶性質, 螢光及雙光子吸收性質, 相關的光化學及光物理之量測與探討 對發展成光學運用材料會有很大的助益. banana, disc, dendrimer, and orthoconics. Depending upon the position and the number of peripheral chains, mesophase structure changes from calamitic to columnar. This study affords the information of molecular structure-mesophase relationships. Ferroelctric and antiferroelectric proerties of the banana types will be characterized by application of electrical fields. Molecules synthesized in this study, either mesogens or nonmesogens, exhibit intense fluorescence (photo-active or electro-active) and two-photon absorption fluorescence. These materials are highly useful for optical, electro-optical, and light emitting applications. The results obtained are important for the design of these materials for applications.[[sponsorship]]行政院國家科學委員

ISR@bucknell

isr@bucknell was a newsletter published by Bucknell University\u27s Information Services and Resources department (later Library and Information Technology). The publication served the community by providing software, project, and service updates. Regular features included a letter from the Associate Vice President for Information Services and Resources, the Ask ISR column, and featured ISR web pages. This issue includes the following articles: Blackboard Rocks, Faculty Focus, The Company We Keep, Appletree Alley, Citation Searching is Here, Bucknell Banner Web, Ask ISR

单、双胎早产的高危因素及早产儿结局比较研究

目的探讨双胎早产与单胎早产高危因素的特点以及单、双胎早产儿的结局。方法回顾性分析广州医科大学附属第三医院2009年1月至2015年12月的单、双胎孕产妇与新生儿临床数据资料。结果研究期间在该院分娩的36 931例新生儿,双胎2080例,单胎34 851例,其中早产5877例,双胎早产1395例(双胎早产组),早产率为67.07%;单胎早产4482例(单胎早产组),单胎早产率为12.86%,总计早产发生率为15.91%,双胎早产率明显高于单胎,差异有统计学意义(P22~26岁组、>26~30岁组、>30~34岁组、>34~39岁组和>39岁组中,双胎早产率均明显高于单胎(单胎早产率对双胎早产率分别为:19.65%vs.64.86%、11.45%vs.70.85%、10.49%vs.68.16%、12.88%vs.65.41%、19.67%vs.64.51%、22.83%vs.68.42%,P均<0.05);单、双胎孕产妇不同孕周出生率比较,双胎在孕20~37周之间的出生率均高于单胎出生率;对早产的高危因素进行对比分析,双胎早产组中人工授精、体外受精-胚胎移植、羊水过多、胎膜早破、妊娠期糖尿病、妊娠期肝内胆汁淤积症的比例均明显高于单胎早产组,差异有统计学意义(1.79%vs.0.16%、1.79%vs.0.16%、2.79%vs.1.38%、32.48%vs.29.65%、19.50%vs.15.84%、2.22%vs.1.41%,P均<0.05);对新生儿的结局进行比较,单胎早产组中死胎、出生缺陷、新生儿呼吸窘迫综合征发生率均明显高于双胎早产组(8.68%vs.2.22%、11.20%vs.8.52%、15.35%vs.12.90%,P均<0.05),1 min、5 min、10 min Apgar评分双胎早产组明显高于单胎早产组,差异有统计学意义[(9.43±0.023)min vs.(9.06±0.026)min、(9.85±0.013)min vs.(9.69±0.016)min、(9.92±0.011)min vs.(9.81±0.014)min,P均<0.05]。结论双胎发生早产的风险显著高于单胎,与单胎早产相比,人工授精、体外受精-胚胎移植、羊水过多、胎膜早破、妊娠期糖尿病、妊娠期肝内胆汁淤积症等高危因素与双胎早产的关系更加密切,早产儿结局优于单胎早产组。国家重点研发计划(2016YFC1000405/2016YFC1000303);;国家自然科学基金(81571518

r DNA sequence analysis and morphological redescription of Empoasca onukii from the tea growing area of Fujian

重新描述了小贯小绿叶蝉的形态结构,尤其是头部色斑、翅脉、腹部内突、下生殖板及其刚毛着生位置,并增加了足部(刺毛列)特征描述。通过PCr技术克隆得到该物种的r dnA序列,包括部分18S(1 843bP)和28S序列(667 bP)以及完整的5.8S(155 bP)、ITS1(3 114 bP)和ITS2序列(1 008 bP)。序列分析表明,18S,5.8S,28S与其他物种间具有90%~95%的序列一致性;而ITS1和ITS2序列变异性非常大。碱基组成比率分析显示ITS1以及ITS2具有AT偏好性,前者A+T占66.0%,后者占65.1%。与亲缘种的比较分析显示ITS1和ITS2具有丰富的多态位点,并且ITS2更适用于近缘种的分子鉴定。The morphological structures of Empoasca onukii,the cephalic splashes,vein,abdominal apodemes,subgenital plate and the arrangement of its bristles,and the characteristics of legs were redescribed,especially the arrangement of spines were added.Ribosomal DNA( r DNA) including partial of 18S( 1 843 bp),28S( 667 bp) and complete 5.8S( 155 bp),ITS1( 3 114 bp),ITS2( 1 008 bp) were isolated by PCR technology.Sequence analysis indicated that 18 S,5.8S and 28 S had high sequence identity( 90%- 95%) with other insects; however,ITS1 and ITS2 showed much variability.The analysis of base composition showed that ITS1 and ITS2 were more preferences for AT( contained 66.0% and 65.1% A + T,respectively).Comparison with the phylogenetic species revealed that ITS1 and ITS2 from E.onukii had rich polymorphic loci and ITS2 was more suitable for molecular identification of closely related species.国家自然科学基金(81171595

H_2S gas sensitivity of UV light activated WO_3 gas sensors

以热氧化钨丝法制备的WO3纳米材料为基材制备了厚膜气敏元件,在常温、紫外光激发条件下实验测试了所制纯WO3气敏元件对不同体积分数的H2S气体的气敏特性曲线,探讨了元件对H2S的灵敏度与紫外光的辐射通量密度的依赖关系。结果表明,常温、无紫外光照下WO3气敏元件对H2S不敏感,而在常温及紫外光激发下WO3气敏元件对H2S的灵敏度显著增大,且随着紫外光辐射通量密度增加,元件对H2S的灵敏度先增大而后减小。The thick film gas sensors were prepared by using WO3 nano-materials that prepared by the method of thermal oxidation of tungsten.Under the condition of room temperature and UV excitation,gas sensing characteristic curves of the prepared pure WO3 gas sensors to H2S gas with different volume fractions were tested.Dependencies between sensitivity of WO3 gas sensors to H2S and UV radiant flux density were investigated.The results show that under the room temperature condition,the WO3 gas sensors are not sensitive to H2S without UV irradiation,while the WO3 gas sensors are significantly sensitive to H2S with UV excitation,and with the increase of UV radiant flux density,the sensitivity of gas sensors to H2S first increases and then decreases.福建省省属高校科研专项资助项目(No.JK2011039); 福建省自然科学基金资助项目(No.2012D110;No.2013J05014); 国家级大学生创新项目资助(No.201310395003

Hypothyroidism after Radiotherapy to the Neck

markdownabstract__Abstract__ Bone is a highly dynamic tissue that is permanently remodeled as an intrinsic mechanism to regenerate bone during life, to accomplish longitudinal growth, and to generate new bone during fracture repair. As bone formation must match closely the amount of bone that is resorbed at each site, bone remodeling is controlled by the coupled actions of osteoclasts and osteoblasts. Osteoblasts control the formation and activity of osteoclasts that are responsible for the initiation and execution of resorption at remodeling sites. The bone resorbed by osteoclasts is replaced through the differentiation and activity of osteoblasts. This coupling of the two processes is essential for bone balance. Due to age, sex hormone status, cancer and a variety of diseases associated with an activation of the immune system, the balance between bone resorption and formation can be shifted leading to local or systemic bone loss that ultimately results in osteoporosis. Osteoporosis is a prevalent skeletal disorder in the elderly that is characterized by impaired bone strength and increased fracture risk. It is associated with reduced life quality and increased mortality. On the other hand, excessive bone formation can give rise to sclerosing bone disorders that include many rare and often hereditary osteochondrodysplasias (e.g. osteopetrosis, Van Buchem disease and sclerosteosis), but can also be caused by a variety of dietary, metabolic, endocrine, hematologic, infectious or neoplastic disorders