The eye splash injuries of echinococcal fluid during surgery of the peritoneal ecohinococcosis: our experience due to two cases

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Antibiotic Consumption Index and Effects of Restricted Antibiotic Use in Dicle University Hospital

The objective consumption rate of antibiotics at our hospital has been measured using “antibiotic consumption index (ACI)” described by World Health Organization. In our hospital, ACI was found 90.7 DDDs/100-Bed Day (BD). In the first level of study, antimicrobial consumption was measured. In the second level, an educational intervention program was started for four of the departments (the study departments). The incidence of hospital infections was monitored during the first and second six-month periods. The index was 128 to 83 in burn unit, 109.8 to 84 in department of nephrology, 102.7 to 90 in thoracic and cardiac surgery (TCS) and 71.5 to 64 in neurosurgery. There was no remarkable change in control departments that 62.7 to 60.7 in gastroenterology and 103 to 106.5 DDDs/100-BD in haematology. Approximately 80.000 dollar were saved from antibiotic budget in the four study departments during the second semester. In the study departments, nosocomial infection rate was found 8.3% in the first semester and 4.9% in the second semester. As a conclusion, educational programs for rational antibiotic consumption and consultations from infectious diseases department are thought to be effective to prevent irrational antibiotic consumption and our new antibiotic policy did not resulted in an increase in nosocomial infection in our hospital

EFFICACY OF COLISTIN AND NON-COLISTIN MONOTHERAPIES IN MULTI-DRUG RESISTANT ACINETOBACTER BAUMANNII BACTEREMIA/SEPSIS

Objective: This retrospective study aimed to investigate the efficacies of colistin and non-colistin monotherapies in multi-drug resistant Acinetobacter baumannii bacteremia (MDR-AB)

Clinical and molecular evaluation of MEFV gene variants in the Turkish population: a study by the National Genetics Consortium

Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder with recurrent fever, abdominal pain, serositis, articular manifestations, erysipelas-like erythema, and renal complications as its main features. Caused by the mutations in the MEditerranean FeVer (MEFV) gene, it mainly affects people of Mediterranean descent with a higher incidence in the Turkish, Jewish, Arabic, and Armenian populations. As our understanding of FMF improves, it becomes clearer that we are facing with a more complex picture of FMF with respect to its pathogenesis, penetrance, variant type (gain-of-function vs. loss-of-function), and inheritance. In this study, MEFV gene analysis results and clinical findings of 27,504 patients from 35 universities and institutions in Turkey and Northern Cyprus are combined in an effort to provide a better insight into the genotype-phenotype correlation and how a specific variant contributes to certain clinical findings in FMF patients. Our results may help better understand this complex disease and how the genotype may sometimes contribute to phenotype. Unlike many studies in the literature, our study investigated a broader symptomatic spectrum and the relationship between the genotype and phenotype data. In this sense, we aimed to guide all clinicians and academicians who work in this field to better establish a comprehensive data set for the patients. One of the biggest messages of our study is that lack of uniformity in some clinical and demographic data of participants may become an obstacle in approaching FMF patients and understanding this complex disease