1,303 research outputs found

    Journal Staff

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    Purpose - This article aims to investigate how R&amp;D employees use their social networks to acquire user information and how this information is used in the development of new products. Design/methodology/approach - A single case study was conducted within a business unit at a multinational medical technology company. Data were collected through a mixed method. Findings - The results show that many R&amp;D employees lack social networks through which they can acquire information about the users' needs. However, some R&amp;D employees establish cost-efficient relationships to people with a direct experience of using the company's products. These relationships are established over time and are often used in a rather informal way to acquire user information. Moreover, the results show how R&amp;D employees are purposefully complementing these relationships with more occasional interactions with people who hold direct and indirect use experiences. Research limitations/implications - As with most single-case studies, it will be important to replicate this investigation in other contexts to clarify the generalizability of the findings. Practical implications - The article shows how important it is that management provides R&amp;D employees with opportunities to establish, nurture and utilize relationships conducive to information about the users' needs. The article provides some advice on how this can be accomplished. Originality/value - This is one of the first articles that clearly explain how R&amp;D employees use their social networks to acquire user information for the development of new products.QC 20150112. Updated from accepted to published.</p

    Biases in estimating repeatability of milk and butterfat production

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    Sequence Analysis of the E3 Region and Fiber Gene of Human Adenovirus Genome Type 7h

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    AbstractAdenovirus type 7h is currently the predominant virulent genome type of serotype 7 isolated in Argentina, Chile, and Uruguay in association with severe infantile pneumonia. In order to characterize possible molecular determinants of pathogenicity, the nucleotide sequence of a 5904-bp fragment (76 to 93 mu) containing the entire E3 region and the fiber gene of Ad7h was established. The organization of the ORFs within the E3 region was similar to that reported for the prototype strains of Ad7 and Ad3. A comparison of the nucleotide and amino acid sequences of all ORFs revealed a higher homology between Ad7h and Ad7p than between Ad7h and Ad3 for 12.0K and 16.1K, whereas the 15.3K ORF and the adjacent fiber gene were strikingly more homologous to those of Ad3 (99.5 vs 81.1% and 98.2 vs 66.6%, respectively). The equivalent to ORF 7.7K in Ad7p was missing in Ad7h due to a deletion and a mutation affecting the start codon (ATG → ATT). Although the hemagglutinin of the Ad7h fiber could not be characterized due to its lack of activity on monkey erythrocytes, our results indicate that Ad7h is an intermediate strain 7-3

    Nanoplasmonic hydrogen sensing

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    In this review we discuss the evolution of surface plasmon resonance and localized surface plasmon resonance based hydrogen sensors. We put particular focus on how they are used to study metal-hydrogen interactions at the nanoscale, both at the ensemble and the single nanoparticle level. Such efforts are motivated by a fundamental interest in understanding the role of nanosizing on metal hydride formation processes. However, nanoplasmonic hydrogen sensors are not only of academic interest but may also find more practical use as all-optical gas detectors in industrial and medical applications, as well in a future hydrogen economy, where hydrogen is used as a carbon free energy carrier

    “SANGUE NO TANOA” ... OU O APELO DO GRANDE OCEANO

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    Se plaçant dans une perspective géopoétique, l’auteur contested’abord le discours triomphaliste de l’Occident concernant les voyagesde découverte afin de proposer un trajet donnant accès à la parole desvaincus, en l’occurence à celle des peuples du Pacifique et en particulier,à ceux de Mélanésie. Ce faisant, il met en lumière l’opposition, nonseulement économique, mais aussi spirituelle. Se plaçant dans uneperspective géopoétique, l’auteur conteste d’abord le discourstriomphaliste de l’Occident concernant les voyages de découverte afin deproposer un trajet donnant accès à la parole des vaincus en s’appuyantentre autressur des textes de poètes du Pacifique et sur le travail de JoëlBonnemaison au sujet des habitants de Tanna

    An action learning network method for increased innovation capability in organizations

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    Product innovation in highly complex and technological areas, such as medical technology, puts high requirements on innovation capability of an organization. Previous research and publications have highlighted organizational issues and learning matters as important and necessary for the development of innovation capability. Action learning require reflections of the ways things are carried out, changes in the current actions, implementation and improvement and thereafter another round of reflections as in the learning cycle. This might be difficult for one organization to carry out internally and therefore this research use a learning network method with several organizations involved in the learning cycle. The purpose of this article is to describe and discuss a learning network method used in a present research project carried out in the med tech industry. The research project aims at increasing the innovation capability of the participating organizations. The method used, is based on action learning and involves representatives from industrial partners, public health organizations, and academic partners. The different organizations run innovation projects over a time period of three years, and meet three times a year in learning network sessions with the purpose of developing knowledge by interaction between the projects and the different actors. During these learning network sessions the participants are facilitated to go through the different phases, reflections, new concepts, new actions, implementations and new reflections. The paper elaborates on theories of innovation capability and learning network. Furthermore, the action learning network structure, the experiences gained in the initial phases of the project, and experience of action learning and learning networks is presented. The importance of trust building between partners in the network in order to facilitate action learning and development of innovation capability is experienced and discussed, as well as the learning that takes place in the interaction between academics from different disciplines in collaboration with practitioners

    Thigh muscle strength and endurance in patients with COPD compared with healthy controls

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    SummaryThe aim of this study was to evaluate thigh muscle strength and endurance in patients with COPD compared with healthy controls. Forty-two patients (26 women; 16 men) with moderate to severe COPD and 53 (29 women; 24 men) age-matched healthy controls participated in the study. The subjects were tested for maximum voluntary contractions (MVC), endurance and fatigue of the thigh muscles on an isokinetic dynamometer (KinCom®). Endurance was expressed as the number of attained repetitions of knee extension and muscle fatigue as a fatigue index (FI).MVC in knee extension was 17% lower in female patients (P=0.017) but no difference was found in male patients (P=0.56) compared to controls. MVC in knee flexion was lower both in female (51%) (P<0.001) and male patients (40%) (P<0.001) compared to controls. Both female and male patients had significantly lower muscle endurance compared to controls. Female patients had a higher FI (22.5%) than female controls (10%) (P=0.001) while no difference was found regarding FI between male patients (15%) and male controls (10%) (P=0.103). The level of self-reported everyday physical activity did not differ between groups.The results showed impaired skeletal muscle function in COPD, except for MVC in knee extension in male patients. Female patients seemed to be more prone to decrease in thigh muscle function. More focus on improving muscle strength and muscle endurance should be considered when designing pulmonary rehabilitation programs. Patients with preserved level of physical activity can be included in exercise programs and gender-related differences should be taken into account
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