Better Reviews

This is a documentary paper on the Better Review PHP project. This project contains a local directory guide for the general users who can get registered to the website and write or check reviews and ratings for any particular business, shop, dine, and professionals. The admin can control the whole process to provide authenticity and reliance. The business owners can also promote their business through this website and get public search as public get to know about new business in the featured service option on the website. Business users can send promotional offers to the users that posted their reviews in their business page. Users will be receiving notifications whenever a new user registers, when the user wants to upgrade from general account to a business account, when their business account is posted in featured services etc. The data is stored through MySQL and the front end is implemented through Bootstrap, HTML5, jQuery, and core JS. In our project we use XAMPP control panel to connect with Apache Server, PHP and MYSQL. In this documentary presentation, we discuss about the website in detail and explain its workflows and several issues. We also explain the architecture design, internal and external risk analysis, functional area, etc. The document contains other possible issuers that are recovered to complete the project successfully and implement the website for users to know information and recommendations about local business though one search

microstructural and thermophysical properties of uo2-mo composite reactor fuels

Nuclear fuel performance under normal operating conditions and extreme accident conditions have studied using experimental procedures to investigate the microstructural and thermophysical properties of the fuel. Attention has been drawn to the catastrophic nuclear power station accident at the Fukushima Daiichi in Japan. After the reactor system's failure, efforts are focused on preventing the existing nuclear fuel, uranium dioxide (UO2), and zirconium (Zr), system from melting. Research is required to replace the fuel and clad system with a more robust system that can withstand accidents. With the recognition of associated risks with the current fuel, hence, developing an accident-tolerant fuel (ATF) became a major motivation for research. In this work, Molybdenum (Mo) has been deployed as an additive material in UO2 fuel due to its high thermal conductivity, high boiling point, high melting point, and low thermal neutron absorption cross-section. The nuclear reactor safety analysis showed that thermal conductivity is an essential property of fuel because it regulates fuel operating temperature and therefore influences the safety of reactor operation. Low thermal conductivity leads to the rapid meltdown at the core of the fuel pellet during the loss of coolant scenario. Apart from thermal conductivity, pellet microstructure and density also played an essential role in fission gas buildup and release, the accumulation of the fission gas in form of voids in the center of fuel pellets. Therefore, three major critical areas of focus have been identified in this research: i) Enhanced thermal conductivity of UO2-Mo composite fuel for high-temperature accident scenarios, ii) Evaluation of the pellet microstructure, grain size, texture, and grain boundary character distribution in UO2-Mo composites, and iii) Optimizing the high densification of the UO2-Mo composite fuel pellets. One of the limitations of the accident-tolerant fuel has the difficulty of processing dense pellets by the conventional sintering methods. Hence the fabricating of UO2-Mo composite fuels by spark plasma sintering (SPS) was proposed, and the effect of the sintering parameters on the density, microstructure, and thermal conductivity of UO2-Mo composite fuel have established. Finally, a composite fuel of UO2-Mo (micro and nano particles) has been manufactured with enhanced thermal conductivity

Managing Mysql Cluster Data Using Cloudera Impala

AbstractMySQL Cluster is a widely used clustered database used to store and manipulate data which has a shared-nothing clustering for the MySql database management system providing high availability and high throughput with low latency. The problem with MySQL Cluster is that as the data grows larger, the time required to process the data increases and additional resources may be needed. With Hadoop and Impala,data processing time can be faster than MySql cluster and probably faster than Hive and Pig. This paper provides preliminary results. Evaluation results indicates that Impala achieves acceptable perfomance for some data analysis and processing tasks even compared with Hive and Pig and MySql cluster

Mela: Vessels of Ephemeral Architecture

In states of temporality, conventions can be challenged and reimagined. Ephemeral architecture responds to fluctuating conditions and are often built with lightweight, recycled materials that allow for reconfiguration and reinvention. Melas, Sanskrit for gathering, become a lens through which ad hoc urbanism can be further explored in its most idealized form. Melas include gatherings of all scales that are commercial, celebratory, or religious. The large crowds and temporary nature of these events allow for thoughtful ephemeral configurations to be tried and tested. The largest gathering of humans in the world is the Kumbh Mela in Prayagraj, India. This religious pilgrimages creates an alternate reality by temporarily diminishing differences in social and economic classes and bringing people together through a share spiritual belief. The rapid construction and disassembly make the city surreal. For a few moments each year, this is the densest city in the world, but there are no skyscrapers or mega structures. Everything, including the infrastructure, is made at the scale of the individual, creating a sense of horizontality against the backdrop of the vast Ganges floodplain. The temporary nature of the Mela is what allows it to interrupt reality in profound ways. This thesis speculates on the transcendental atmosphere of the KumbhMela by reconfiguring materials from the event to create temporary escapes from ordinary life that exist before and after the festival. The proposed floating pavilions allude to the mela in the off season by becoming literal vessels of ephemerality and allowing occupants to reconnect to the sacred river. The design implements simple assembly methods to transform portions of the pontoon bridges into spiritual retreats, which could be replicated for other temporary needs. The proposal conceptually draws from the ephemeral megacity and physically reuses elements of the festival to demonstrate the scalability and adaptability of this form of design

Effect of bacterial nanocellulose binding on the bactericidal activity of bovine lactoferrin

Bovine lactoferrin (bLF) has been extensively described as a wide spectrum antimicrobial protein. bLF bactericidal activity has been mainly attributed to two different mechanisms: environmental iron depletion and cell membrane destabilization. Due to its antimicrobial properties, bLF has been included in the formulation nutraceutical food products and edible active packages. This work comprises the experimental evidence of the requirement of bLF unrestricted mobility (free bLF) to effectively perform its bactericidal action. To assess the unrestricted and restricted bLF activity, a nontoxic matrix of bacterial nanocellulose (BNC) was used as carrier, and as an anchoring scaffold, respectively. Therefore, BNC was functionalized with bLF through two different methodologies: (i) bLF was embedded within the three-dimensional structure of BNC and; (ii) bLF was covalently bounded to the nanofibrils of BNC. bLF efficiency was tested against two bacteria isolated from clinical specimens, Escherichia coli and Staphylococcus aureus. bLF concentration after covalent binding to BNC was two-fold higher in comparison to the embedding method. Nevertheless, only the embedded bLF exhibited a significant bactericidal activity, due to bLF ability to permeate the BNC matrix and execute its bactericidal action.Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/ 04469/2020 unit and BioTecNorte operation (NORTE-01-0145-FEDER- 000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do NortePortuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding of UID/FIS/04650/2020 and projects PTDC/BTM-MAT/28237/ 2017 and PTDC/EMDEMD/28159/2017Portuguese Foundation for Science and Technology (FCT) SFRH/BD/64901/2009 and SFRH/BD/111478/2015Spanish State Research Agency (AEI) and the European Regional Development Fund through the project PID2019-106099RBC43/ AEI/10.13039/501100011033 and from the Basque Government Industry and Education Department under the ELKARTEK, HAZITEK and PIBA (PIBA-2018-06) programs, respectivelyinfo:eu-repo/semantics/publishedVersio

Cystatin C Deficiency Promotes Epidermal Dysplasia in K14-HPV16 Transgenic Mice

Cysteine protease cathepsins are important in extracellular matrix protein degradation, cell apoptosis, and angiogenesis. Mice lacking cathepsins are protected from tumor progression in several animal models, suggesting that the regulation of cathepsin activities controls the growth of various malignant tumors.We tested the role of cathepsins using a mouse model of multistage epithelial carcinogenesis, in which the human keratin-14 promoter/enhancer drove the expression of human papillomavirus type 16 (HPV16) early region E6/E7 transgenes. During the progression of premalignant dysplasia, we observed increased expression of cysteine protease cathepsin S, but concomitantly reduced expression of cathepsin endogenous inhibitor cystatin C in the skin tissue extract. Absence of cystatin C in these transgenic mice resulted in more progression of dysplasia to carcinoma in situ on the face, ear, chest, and tail. Chest and ear skin extract real time PCR and immunoblot analysis, mouse serum sample ELISA, tissue immunohistological analysis, and tissue extract-mediated in vitro elastinolysis and collagenolysis assays demonstrated that cystatin C deficiency significantly increased cathepsin expression and activity. In skin from both the chest and ear, we found that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation. From the same tissue preparations, we detected significantly higher levels of pro-angiogenic laminin 5-derived γ2 peptides and concurrently increased neovascularization in cystatin C-deficient mice, compared to those from wild-type control mice.Enhanced cathepsin expression and activity in cystatin C-deficient mice contributed to the progression of dysplasia by altering premalignant tissue epithelial proliferation, apoptosis, and neovascularization

Approaches in biotechnological applications of natural polymers

Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento Cientfíico e Tecnológico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de Nvíel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)

Thomas Paine Podcast

Thomas Paine was a political writer who had a great impact on the American Revolution. His work played a significant role in the American independence. The Common Sense and Crisis Papers were highly influential and if not for Thomas Paine it is possible that the American troops would have given up their fight against the British

The Reinterpretation and Transformation of the American Liberal Arts Model in the Indian Context

The rise of liberal arts institutions in India has been a recent development that has taken shape over the past two decades. In this senior thesis, I discuss the ways in which the liberal arts model implemented at FLAME University, India, resonates with and diverges from the prototypical liberal arts model in the United States. I also elicit the determinants that influence the institutional structure and practices of FLAME and study these institutional manifestations in relation to larger social phenomenon. I prepare the groundwork for my project by first reviewing the values and organizational structures of the liberal arts model in the U.S., and conceptualizing the forces that may lead to its transformation in the Indian higher education context. My case study of FLAME is based on interviews and participant observation on campus, along with analysis of collected documents such as program brochures and handbooks. My findings show that FLAME exhibits a hybrid model: it mirrors the American liberal arts education in aspects such as pedagogical methods, classroom environment, and social class positioning of the student body, yet differs in aspects such as program duration, courses offered, and approaches to gender and ethnic diversity. I reflect on the cultural, political and bureaucratic forces that shape this hybrid model and suggest additional lines of study in the field of organizational sociology and educatio