Particle Dynamics Near Kerr-MOG Black Hole

This paper explores the dynamics of both neutral as well as charged particles orbiting near a rotating black hole in scalar-tensor-vector gravity. We study the conditions for the particle to escape at the innermost stable circular orbit. We investigate stability of orbits through effective potential and Lyapunov exponent in the presence of magnetic field. The effective force acting on particle is also discussed. We also study the center of mass energy of particle collision near the horizon of this black hole. Finally, we compare our results with the particle motion around Schwarzschild, Kerr and Schwarzschild-MOG black holes. It is concluded that the external magnetic field, spin parameter as well as dimensionless parameter of the theory have strong effects on particle dynamics in modified gravity.Comment: 22 pages, 6 figures, to appear in EPJ

Accuracy and complications of pedicle screw insertion for lumbar and thoracolumbar fractures

 Background: The accuracy of pedicle screw placement is essential for lumbar and thoracolumbar spine fracture fixation.Purpose: The aim of the present study was to assess the accuracy of the pedicle screw placement with conventional C-arm fuoroscopy-guided in these patients.Methods: A retrospective review identified patients who underwent operative management with thoracolumbar instruments at our hospital between June 2012 and August 2013. Clinical data were acquired from medical records and final screw positions were graded based on a classification of Gertzbein and Robbins.Results: A total of 216 pedicle screws in 52 patients (34 males, mean age 32.6±5.8 years) were evaluated. They were instrumented with transpedicular posterior fixation technique within 72 hours. The follow-up time was 6.1 months (ranging from 1 to 14 months). The screws were graded A (n=43 [19.9%]), B (n=89 [41.2%]), C (n=62 [28.7%]), D (n=21 [9.7%]), and E (n=1 [0.5%]). One of the screws was revised on the second day after surgery due to screw malposition.Conclusion: Based on existing facilities, the findings showed that the pedicle instrumentation screws with transpedicular posterior fixation technique in patients with lumbar and thoracolumbar fractures can be done with acceptable complication rate. However, more advanced equipment as CT navigation (O-arm) is recommended for higher accuracy

Treatment of Cystic Craniopharyngioma with Intracystic Stereotactic Instillation of Phosphorus 32

How to Cite This Article: Shahzadi S, Soltani A, Shahzadi A, Parsa Kh. Treatment of Cystic Craniopharyngioma with Intracystic Stereotactic Instillation of Phosphorus 32. Iran J Child Neurol. Summer 2017; 11(3):31-36.AbstractObjectiveCystic craniopharyngiomas are considered the most common intracranial nonglial tumor in children with the tendency for cyst formations. The aim of this study was to evaluate the effect of intracystic phosphorus 32 (P32) therapies on controlling the growth of the cystic component of craniopharyngioma.Materials & MethodsThis clinical study was conducted on 47 patients with cystic craniopharyngioma from March 1998 to June 2012 at Shohada Tajrish Hospital, Tehran, Iran.Patients were treated with stereotactic intracystic P32. The mean cyst volume was 23.5 ml, and the dose of radiation to the inner cyst wall was 250 Gy.ResultsThe overall response rate was 78.1% and the mean survival was 113.1±11months.The survival rate at 1, 3, 5, and 10 years after p32 therapy was 91%, 77%, 73%, and 52%, respectively. There was no mortality related to the procedure and no visual or endocrinal deterioration. Visual improvement occurred in 88% of patients presented with recent deterioration due to the cyst enlargement.ConclusionIntracystic p32 therapy was an effective and almost safe procedure for the treatment of cystic component of craniopharyngioma. References1. Shahzadi S, Sharifi G, Andalibi R, Zali A, Ali-Asgari A. Management of cystic craniopharyngiomas with intracavitary irradiation with P32. Arch Iran Med 2008;11(1):30-4.2. Komotar RJ, Roguski M, Bruce JN. Surgical management of craniopharyngiomas. J Neurooncol 2009;92(3):283- 96.3. Garnett MR, Puget S, Grill J, Sainte-Rose C. Craniopharyngioma. Orphanet J Rare Dis 2007;2:18.4. Dekkers OM, Biermasz NR, Smit JW, et al. Quality of life in treated adult craniopharyngioma patients. Eur J Endocrinol 2006;154(3):483-9.5. Bartels U, Laperriere N, Bouffet E, Drake J. Intracystic therapies for cystic craniopharyngioma in childhood. Front Endocrinol (Lausanne) 2012;3:39.6. Basso A, Socolovsky M, Goland J. Actualization of treatment options in Craniopharyngioma: a comparative analysis of different therapeutic modalities. The World Federation of Neurosurgical Societies (WFNS): Available From: http://www.wfns.org/pages/read_the_reviews/97. php?rid=4 7. Leng LZ, Greenfield JP, Souweidane MM, Anand VK, Schwartz TH. Endoscopic, endonasal resection of craniopharyngiomas: analysis of outcome including extent of resection, cerebrospinal fluid leak, return to preoperative productivity, and body mass index. Neurosurgery 2012;70(1):110-23.8. Zhao R, Deng J, Liang X, Zeng J, Chen X, Wang J. Treatment of cystic craniopharyngioma with phosphorus-32 intracavitary irradiation. Childs Nerv Syst 2010;26(5):669-74.9. Kobayashi T, Kageyama N, Ohara K. Internal irradiation for cystic craniopharyngioma. J Neurosurg 1981;55(6):896-903.10. Trippel M, Nikkhah G. Stereotactic neurosurgical treatment options for craniopharyngioma. Front Endocrinol (Lausanne) 2012;3:63.11. Fahlbusch R, Honegger J, Paulus W, et al. Surgical treatment of craniopharyngiomas: experience with 168patients. J Neurosurg 1999;90(2):237-50.12. Elliott RE, Hsieh K, Hochm T, et al. Efficacy and safety of radical resection of primary and recurrentcraniopharyngiomas in 86 children. J Neurosurg Pediatr 2010;5(1):30-48.13. Müller HL, Gebhardt U, Teske C, et al. Post-operative hypothalamic lesions and obesity in childhood craniopharyngioma: results of the multinational prospective trial KRANIOPHARYNGEOM 2000 after 3-year follow-up. Eur J Endocrinol 2001;165(1):17-24.14. Clark AJ, Cage TA, Aranda D, et al. Treatmentrelated morbidity and the management of pediatric craniopharyngioma: a systematic review. J Neurosurg Pediatr 2012;10(4):293-301.15. Schoenfeld A, Pekmezci M, Barnes MJ, et al. The superiority of conservative resection and adjuvant radiation for craniopharyngiomas J Neurooncol 2012;108(1):133-9.16. Jang WY, Lee KS, Son BC, et al. Repeat operations in pediatric patients with recurrent craniopharyngiomas. Pediatr Neurosurg 2009;45(6):451-5.17. Barriger RB, Chang A, Lo SS, Timmerman RD, Des Rosiers C, Boaz JC, et al. Phosphorus-32 therapy for cystic craniopharyngiomas. Radiother Oncol 2011;98(2):207-12.18. Tian ZM. Stereotactic intracavitary irradiation of huge cystic craniopharyngiomas. Zhonghua Wai Ke Za Zhi 1992;30(2):102-3.19. Pollock BE, Lunsford LD, Kondziolka D, ad et al. Phosphorus-32 intracavitary irradiation of cystic craniopharyngiomas: current technique and long-term results. Int J Radiat Oncol Biol Phys 1995 ;33(2):437-46.20. Voges J, Sturm V, Lehrke R, et al. Cystic craniopharyngioma: long-term results after intracavitary irradiation with stereotactically applied colloidal beta-emitting radioactive sources. Neurosurgery 1997;40(2):263-9.21. Julow J, Backlund EO, Lányi F, et al. Long-term results and late complications after intracavitary yttrium-90 colloid irradiation of recurrent cystic craniopharyngiomas. Neurosurgery 2007;61(2):288-95.22. Hasegawa T, Kondziolka D, Hadjipanayis CG, Lunsford LD. Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation. Neurosurgery 2004;54(4):813-20.23. Anderson DR, Trobe JD, Taren JA, Gebarski SS. Visual outcome in cystic craniopharyngiomas treated with intracavitary phosphorus-32. Ophthalmology 1989;96(12):1786-92.24. Kodama T, Matsukado Y, Uemura S. Intracapsular irradiation therapy of craniopharyngiomas with radioactive gold: indication and follow-up results. Neurol Med Chir (Tokyo) 1981;21(1):49-58.25. Backlund EO, Axelsson B, Bergstrand CG, et al. Treatment of craniopharyngiomas--the stereotactic approach in a ten to twenty-three years’ perspective. I. Surgical, radiological and ophthalmological aspects. Acta Neurochir (Wien 1989;99(1-2):11-9.26. Van den Berge JH, Blaauw G, Breeman WA, et al. Intracavitary brachytherapy of cystic craniopharyngiomas. J Neurosurg 1992;77(4):545-50.

Sustainability (definition, examples, pillars, sustainable development.....................)

Treball Final de Màster Universitari en Direcció d'Empreses / Master in Management. Codi: SRO011. Curs acadèmic 2021/2022The purpose of this article is to analyze the concept of sustainability by emphasizing various facts such as environmental, social, and economic and its development from the perspective of sustainable development. The thesis is divided into two chapters. Chapter 1 is about the definition of sustainability, and in chapter 2, the perspectives on sustainability are discussed. This thesis analyzes its importance in the business field. The main objective of this thesis is to analyze the sustainability of the Swedish furniture company, Ikea, and to propose a sustainable development strategy for the company. Design/Methodology: To achieve these objectives, I proposed a research model based on the theoretical and empirical background of Ikea

Factors Associated Patient Waiting Time at Outpatient Department in Allied Hospital Faisalabad

Background: Extreme long waiting time in outpatient department in the Constant challenge for patients and the health providers of these services. Waiting long time are related with poor outcome to treatment, lost appointment and failure or delay in start of basic treatment. The time a patient spends at every service point before being examine by a health supplier and the overall total time a patient spends in a health facility from the arrival time to the departure time is a main cause towards the perception of the patient towards the care received. Objective: To define waiting time and related factors among patients who attend outpatient department of the Allied Hospital Faisalabad. Methodology:  Cross-sectional study was done, data collection was Conducted on 354 outpatient over a period of four weeks by an interview and pre planed questionnaire used to select patients in outpatient department .To analyses all data the data was cleaned then planned questionnaire with the time-tracking piece.  The method that was used Simple random sampling after this ,The data was entered in the Statistical Package for Social Sciences (SPSS) 20 .Results: In total 354 patients were traced an interviewed 55.4 minutes usual time was noted .Many of the patients waited in the outpatient department for 65 minutes to obtain the facilities they had need. In the doctor office lengthiest waiting time was recorded which was 13.2 minutes Mostly patient came at the outpatient department to received services new consultations and follow up review. 68 % person gave response that they felt the time they had spent at outpatient department was acceptable. While, many of the patients at outpatient department 62.7% advised that waiting time can be reduced by improving availability of workers at their working points.  Department and the mean waiting time at the outpatient department is the first stair to reducing waiting time .There is a need to change internal practices and then implement at the outpatient department.  About one hour and 5 minutes many of patients spent time at the facility to be given. Maximum patients felt the total time spent in the facility is acceptable but recommended that improving availability of health workers at their stations will reduce the Distinguishing the areas that cause to delay in meet health care services at the outpatient waiting time of the patient and hence improve the provision of services.

Radiomics analyses for outcome prediction in patients with locally advanced rectal cancer and glioblastoma multiforme using multimodal imaging data

Personalized treatment strategies for oncological patient management can improve outcomes of patient populations with heterogeneous treatment response. The implementation of such a concept requires the identification of biomarkers that can precisely predict treatment outcome. In the context of this thesis, we develop and validate biomarkers from multimodal imaging data for the outcome prediction after treatment in patients with locally advanced rectal cancer (LARC) and in patients with newly diagnosed glioblastoma multiforme (GBM), using conventional feature-based radiomics and deep-learning (DL) based radiomics. For LARC patients, we identify promising radiomics signatures combining computed tomography (CT) and T2-weighted (T2-w) magnetic resonance imaging (MRI) with clinical parameters to predict tumour response to neoadjuvant chemoradiotherapy (nCRT). Further, the analyses of externally available radiomics models for LARC reveal a lack of reproducibility and the need for standardization of the radiomics process. For patients with GBM, we use postoperative [11C] methionine positron emission tomography (MET-PET) and gadolinium-enhanced T1-w MRI for the detection of the residual tumour status and to prognosticate time-to-recurrence (TTR) and overall survival (OS). We show that DL models built on MET-PET have an improved diagnostic and prognostic value as compared to MRI

The Impact of Human Resources Practices on Organizational Performance: Mediating Role of Supply Chain Operational Performance Among Pakistani SMEs

Purpose: The primary aim of this quantitative study was to test the impact of the cultural capabilities and training & Development on Organizational Performance of Pakistani SMEs. In order to achieve the goals of the study, literature review has been done; tools and seven hypotheses were developed.   Methodology: data have been collected through structured self-administered questionnaire adopted and adapted from the earlier similar studies.  Based on 62 itemized survey, data have been collected from 379 Pakistani SMEs situated in ten cities. A pilot study was conducted and data analysis techniques as; Descriptive, Pearson Correlation, Regression, Convergent Validity, Discriminate validity, Composite reliability, Partial Least Square through Structural Educational Modeling, are employed to check the reliability, validity of model fitness and testing the hypotheses.     Conclusion: Study methodologies can include structural equation modelling and enhanced monitoring of supply chain management as well facilitating to their success can be resulted from the continued research in this area, as well as application of the model to different enterprises and situations.   Implications: This study provided guidance and controlling panel for the Small and Medium Enterprises Authority (SMEs) of Pakistani government at first place as it advises either SMEDA should pay attention to modernize SMEs with the help of technology and influence performance of industry. Future study may employ other methodologies to evaluate and confirm the currently presented casual links