Einfluss von Omega-3 Fettsäuren in Form von Triacylglyceriden und Ethylestern auf den Omega-3 Index und Parameter des Lipidstoffwechsels bei Hyperlipidämie-Patienten

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Considering Pigeons for Carrying Delay Tolerant Networking based Internet traffic in Developing Countries

There are many regions in the developing world that suffer from poor infrastructure and lack of connection to the Internet and Public Switched Telephone Networks (PSTN). Delay Tolerant Networking (DTN) is a technology that has been advocated for providing store-and-forward network connectivity in these regions over the past few years. DTN often relies on human mobility in one form or another to support transportation of DTN data. This presents a socio-technical problem related to organizing how the data should be transported. In some situations the demand for DTN traffic can exceed that which is possible to support with human mobility, so alternative mechanisms are needed. In this paper we propose using live carrier pigeons (columba livia) to transport DTN data. Carrier pigeons have been used for transporting packets of information for a long time, but have not yet been seriously considered for transporting DTN traffic. We provide arguements that this mode of DTN data transport provides promise, and should receive attention from research and development projects. We provide an overview of pigeon characteristics to analyze the feasibility of using them for data transport, and present simulations of a DTN network that utilizes pigeon transport in order to provide an initial investigation into expected performance characteristics

Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations - a comparative bioavailability study of fish oil vs. krill oil

<p>Abstract</p> <p>Background</p> <p>Bioavailability of omega-3 fatty acids (FA) depends on their chemical form. Superior bioavailability has been suggested for phospholipid (PL) bound omega-3 FA in krill oil, but identical doses of different chemical forms have not been compared.</p> <p>Methods</p> <p>In a double-blinded crossover trial, we compared the uptake of three EPA+DHA formulations derived from fish oil (re-esterified triacylglycerides [rTAG], ethyl-esters [EE]) and krill oil (mainly PL). Changes of the FA compositions in plasma PL were used as a proxy for bioavailability. Twelve healthy young men (mean age 31 y) were randomized to 1680 mg EPA+DHA given either as rTAG, EE or krill oil. FA levels in plasma PL were analyzed pre-dose and 2, 4, 6, 8, 24, 48, and 72 h after capsule ingestion. Additionally, the proportion of free EPA and DHA in the applied supplements was analyzed.</p> <p>Results</p> <p>The highest incorporation of EPA+DHA into plasma PL was provoked by krill oil (mean AUC_{0-72 h}: 80.03 ± 34.71%*h), followed by fish oil rTAG (mean AUC_{0-72 h}: 59.78 ± 36.75%*h) and EE (mean AUC_{0-72 h}: 47.53 ± 38.42%*h). Due to high standard deviation values, there were no significant differences for DHA and the sum of EPA+DHA levels between the three treatments. However, a trend (<it>p = </it>0.057) was observed for the differences in EPA bioavailability. Statistical pair-wise group comparison's revealed a trend (<it>p </it>= 0.086) between rTAG and krill oil. FA analysis of the supplements showed that the krill oil sample contained 22% of the total EPA amount as free EPA and 21% of the total DHA amount as free DHA, while the two fish oil samples did not contain any free FA.</p> <p>Conclusion</p> <p>Further studies with a larger sample size carried out over a longer period are needed to substantiate our findings and to determine differences in EPA+DHA bioavailability between three common chemical forms of LC n-3 FA (rTAG, EE and krill oil). The unexpected high content of free EPA and DHA in krill oil, which might have a significant influence on the availability of EPA+DHA from krill oil, should be investigated in more depth and taken into consideration in future trials.</p

Guarding Against Foreign Interference in Elections

Developed electoral processes in mature economies in the West have been compromised by external tampering. Singapore has not had to deal with serious cases of foreign interference in its elections. This could, however, change in the future. What can be done to pre-empt this?Published versio

Select Committee on Deliberate Online Falsehoods – After the Recommendations : Now for the Hard Part

The multi-pronged national framework to tackle the spread of malicious content online, as proposed by the Select Committee on Online Falsehoods, is commendable. However, challenges in implementation remain

Bill to Protect from Online Falsehoods : Refinements Needed

The Protection from Online Falsehoods and Manipulation Bill Singapore is set to introduce should be viewed as a first step in developing a suitable approach towards countering the threat of disinformation online. To ensure Singapore develops sufficient resilience, additional details and refinements are needed

Building Resilience Against Disinformation : Need for Wider Education

Increasingly, cyber threats have been directed at targets with economic, political and social impact with the aim of sowing confusion, fraying civic threads, and intensifying existing polarisations. Singapore needs to commit towards instructing the wider public on how to manage disinformation campaigns