185 research outputs found

    An Analysis of Metadiscourse in the Abstracts of English Academic Papers

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    As an important part in academic writing meta discourse has got considerable attention in recent years Abstract plays an important role in academic writings and it reflects the main contents of the whole papers Based on the theory of metadiscourse and the classifications of Hyland this study compared the different frequency and usage of metadiscourse in mathematical and linguistic academic papers Two small abstracts corpora were compiled in this study including 30 mathematical and 30 linguistic abstracts of academic papers from Social Science Citation Index SSCI and Science Citation Index SCI journals The results showed that there appeared more metadiscourse in the abstracts of linguistic academic papers than mathematical academic papers Interactive meta discourse was adopted more than interactional metadiscourse in abstracts of the two disciplines In the use of interactive meta discourse both disciplines demonstrated the same trends in the frequencies of five sub-categories Regarding interactional metadiscourse hedges were the most frequently used meta discourse markers in linguistic academic papers while self mentions were most frequently used in mathematics It is suggested that more interactive meta discourse should be used in abstracts of both arts and science academic paper

    GW26-e3532 miR-433 Controls Cardiac Fibrosis

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    Role of Apoptosis in Cancer Resistance to Chemotherapy

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    Cancer is a leading cause of death in human beings. Surgery, chemotherapy, radiotherapy, immunotherapy, and biologically targeted therapy are common modalities for cancer treatment. However, cancer resistance is common in chemotherapy and often leads to therapeutic failure. This chapter addresses the role of apoptosis in tumor’s resistance to chemotherapy and the underlying mechanisms. Cancer cells are always resistant to apoptotic signals via a series of biochemical changes. Cancer cells are resistant to chemotherapeutic agents that are potent apoptosis inducers via multiple mechanisms, such as upregulated anti-apoptotic signals and downregulated pro-apoptotic signals, faulty apoptotic signaling, faulty apoptosis initiation and implementation, etc. We also discuss the possible approaches to overcoming cancer resistance to chemotherapy due to altered apoptosis

    Emotion Separation Is Completed Early and It Depends on Visual Field Presentation

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    It is now apparent that the visual system reacts to stimuli very fast, with many brain areas activated within 100 ms. It is, however, unclear how much detail is extracted about stimulus properties in the early stages of visual processing. Here, using magnetoencephalography we show that the visual system separates different facial expressions of emotion well within 100 ms after image onset, and that this separation is processed differently depending on where in the visual field the stimulus is presented. Seven right-handed males participated in a face affect recognition experiment in which they viewed happy, fearful and neutral faces. Blocks of images were shown either at the center or in one of the four quadrants of the visual field. For centrally presented faces, the emotions were separated fast, first in the right superior temporal sulcus (STS; 35–48 ms), followed by the right amygdala (57–64 ms) and medial pre-frontal cortex (83–96 ms). For faces presented in the periphery, the emotions were separated first in the ipsilateral amygdala and contralateral STS. We conclude that amygdala and STS likely play a different role in early visual processing, recruiting distinct neural networks for action: the amygdala alerts sub-cortical centers for appropriate autonomic system response for fight or flight decisions, while the STS facilitates more cognitive appraisal of situations and links appropriate cortical sites together. It is then likely that different problems may arise when either network fails to initiate or function properly

    TensorFlow Estimators: Managing Simplicity vs. Flexibility in High-Level Machine Learning Frameworks

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    We present a framework for specifying, training, evaluating, and deploying machine learning models. Our focus is on simplifying cutting edge machine learning for practitioners in order to bring such technologies into production. Recognizing the fast evolution of the field of deep learning, we make no attempt to capture the design space of all possible model architectures in a domain- specific language (DSL) or similar configuration language. We allow users to write code to define their models, but provide abstractions that guide develop- ers to write models in ways conducive to productionization. We also provide a unifying Estimator interface, making it possible to write downstream infrastructure (e.g. distributed training, hyperparameter tuning) independent of the model implementation. We balance the competing demands for flexibility and simplicity by offering APIs at different levels of abstraction, making common model architectures available out of the box, while providing a library of utilities designed to speed up experimentation with model architectures. To make out of the box models flexible and usable across a wide range of problems, these canned Estimators are parameterized not only over traditional hyperparameters, but also using feature columns, a declarative specification describing how to interpret input data. We discuss our experience in using this framework in re- search and production environments, and show the impact on code health, maintainability, and development speed.Comment: 8 pages, Appeared at KDD 2017, August 13--17, 2017, Halifax, NS, Canad
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