185 research outputs found
An Analysis of Metadiscourse in the Abstracts of English Academic Papers
As an important part in academic writing meta discourse has got considerable attention in recent years Abstract plays an important role in academic writings and it reflects the main contents of the whole papers Based on the theory of metadiscourse and the classifications of Hyland this study compared the different frequency and usage of metadiscourse in mathematical and linguistic academic papers Two small abstracts corpora were compiled in this study including 30 mathematical and 30 linguistic abstracts of academic papers from Social Science Citation Index SSCI and Science Citation Index SCI journals The results showed that there appeared more metadiscourse in the abstracts of linguistic academic papers than mathematical academic papers Interactive meta discourse was adopted more than interactional metadiscourse in abstracts of the two disciplines In the use of interactive meta discourse both disciplines demonstrated the same trends in the frequencies of five sub-categories Regarding interactional metadiscourse hedges were the most frequently used meta discourse markers in linguistic academic papers while self mentions were most frequently used in mathematics It is suggested that more interactive meta discourse should be used in abstracts of both arts and science academic paper
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Single Epoch Analysis and Bi-hemisphere Study of Magnetoencephalographic (MEG) Signals using Vector Signal Transformation V3 and Magnetic Field Tomography (MFT)
The biomagnetic inverse problem has no unique solution, nevertheless even a cursory look at the features shown in raw signal can often suffice to highlight strong superficial activity. To do a proper single epoch analysis is normally prohibitively expensive in terms of computing demands. Hence the original aim of this thesis was to use simple efficient signal transformations to characterize superficial generators and contrast the single epoch signature with that extracted from the average signal. The results have intrigued us sufficiently to go beyond the original goal and extract very preliminary estimates of activity across the cerebral hemisphere in single trials.
The original tool, and one that we have used for much of the work, is a simple vector signal transformation called V3. This signal transformation highlights nearby sources; it is a crude but quick estimator of generators directly from the raw MEG signals. Together with Magnetic Field Tomography (MFT), which relies on distributed source analysis of the MEG signals, we have tackled the following specific problems relating to aspects of normal brain function: efficient estimation of generators of magnetic fields; relationship between the average signal and single trials; and interhemispheric differences and relationship between the activity in the left and right hemispheres of the brain.
During the project, we have used as examples auditory evoked MEG measurements obtained from two multichannel systems and applied the V3 and MFT analysis to both the average and single trial signals. In particular, we chose the 40-Hz (or gamma band) auditory response as the study subject. We found that in single epochs similar patterns of high frequency activity are observed in the area around the auditory cortex well before, close to and well after stimulus onset; the sequence of events observed in the average can only represent the evolution of events in single trials in a statistical way; and deep and central areas of the brain may be the seeds for the main deflections observed in the auditory responses
Role of Apoptosis in Cancer Resistance to Chemotherapy
Cancer is a leading cause of death in human beings. Surgery, chemotherapy, radiotherapy, immunotherapy, and biologically targeted therapy are common modalities for cancer treatment. However, cancer resistance is common in chemotherapy and often leads to therapeutic failure. This chapter addresses the role of apoptosis in tumorβs resistance to chemotherapy and the underlying mechanisms. Cancer cells are always resistant to apoptotic signals via a series of biochemical changes. Cancer cells are resistant to chemotherapeutic agents that are potent apoptosis inducers via multiple mechanisms, such as upregulated anti-apoptotic signals and downregulated pro-apoptotic signals, faulty apoptotic signaling, faulty apoptosis initiation and implementation, etc. We also discuss the possible approaches to overcoming cancer resistance to chemotherapy due to altered apoptosis
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Generation of Transfer Functions with Stochastic Search Techniques
This paper presents a novel approach to assist the
user in exploring appropriate transfer functions for the
visualization of volumetric datasets. The search for a
transfer function is treated as a parameter optimization problem and addressed with stochastic search techniques. Starting from an initial population of (random or pre-defined) transfer functions, the evolution of the stochastic algorithms is controlled by either direct user selection of intermediate images or automatic fitness evaluation using user-specified objective functions. This approach essentially shields the user from the complex and tedious "trial and error" approach, and demonstrates effective and convenient generation of transfer functions.Engineering and Applied Science
Emotion Separation Is Completed Early and It Depends on Visual Field Presentation
It is now apparent that the visual system reacts to stimuli very fast, with many brain areas activated within 100 ms. It is, however, unclear how much detail is extracted about stimulus properties in the early stages of visual processing. Here, using magnetoencephalography we show that the visual system separates different facial expressions of emotion well within 100 ms after image onset, and that this separation is processed differently depending on where in the visual field the stimulus is presented. Seven right-handed males participated in a face affect recognition experiment in which they viewed happy, fearful and neutral faces. Blocks of images were shown either at the center or in one of the four quadrants of the visual field. For centrally presented faces, the emotions were separated fast, first in the right superior temporal sulcus (STS; 35β48 ms), followed by the right amygdala (57β64 ms) and medial pre-frontal cortex (83β96 ms). For faces presented in the periphery, the emotions were separated first in the ipsilateral amygdala and contralateral STS. We conclude that amygdala and STS likely play a different role in early visual processing, recruiting distinct neural networks for action: the amygdala alerts sub-cortical centers for appropriate autonomic system response for fight or flight decisions, while the STS facilitates more cognitive appraisal of situations and links appropriate cortical sites together. It is then likely that different problems may arise when either network fails to initiate or function properly
TensorFlow Estimators: Managing Simplicity vs. Flexibility in High-Level Machine Learning Frameworks
We present a framework for specifying, training, evaluating, and deploying
machine learning models. Our focus is on simplifying cutting edge machine
learning for practitioners in order to bring such technologies into production.
Recognizing the fast evolution of the field of deep learning, we make no
attempt to capture the design space of all possible model architectures in a
domain- specific language (DSL) or similar configuration language. We allow
users to write code to define their models, but provide abstractions that guide
develop- ers to write models in ways conducive to productionization. We also
provide a unifying Estimator interface, making it possible to write downstream
infrastructure (e.g. distributed training, hyperparameter tuning) independent
of the model implementation. We balance the competing demands for flexibility
and simplicity by offering APIs at different levels of abstraction, making
common model architectures available out of the box, while providing a library
of utilities designed to speed up experimentation with model architectures. To
make out of the box models flexible and usable across a wide range of problems,
these canned Estimators are parameterized not only over traditional
hyperparameters, but also using feature columns, a declarative specification
describing how to interpret input data. We discuss our experience in using this
framework in re- search and production environments, and show the impact on
code health, maintainability, and development speed.Comment: 8 pages, Appeared at KDD 2017, August 13--17, 2017, Halifax, NS,
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