Understanding the PxS Aspect of Within-Person Variation: A Variance Partitioning Approach

This article reviews a variance partitioning approach to within-person variation based on Generalizability (G) Theory and the Social Relations Model (SRM). The approach conceptualizes an important part of within-person variation as Person x Situation (PxS) interactions: differences among persons in their profiles of responses across the same situations. The approach provided the first quantitative method for capturing within-person variation and demonstrated very large PxS effects for a wide range of constructs. These include anxiety, five-factor personality traits, perceived social support, leadership, and task performance. Although PxS effects are commonly very large, conceptual and analytic obstacles have thwarted consistent progress. For example, how does one develop a psychological, versus purely statistical, understanding of PxS effects? How does one forecast future behavior when the criterion is a PxS effect? How can understanding PxS effects contribute to psychological theory? This review describes potential solutions to these and other problems developed in the course of conducting research on the PxS aspect of social support. Additional problems that need resolution are identified

Nonviolent action: How it works

https://stars.library.ucf.edu/prism/1325/thumbnail.jp

Host directed therapy targeting M. tuberculosis infected macrophages

Includes bibliographical references.2016 Summer.With the rise of drug resistant strains of Mycobacterium tuberculosis (Mtb) and lags in antimicrobial drug development, it is imperative to explore alternative methods of treatment through host-directed adjunct therapies. Hallmarks of Mtb infection are altered host cell glucose metabolism and non-diabetic hyperglycemia, which increase disease severity and bacterial burden. This can be targeted using a combination of metformin and 2-deoxyglucose (2DG) to lower systemic blood glucose and increase metabolic stress in infected macrophages to induce apoptotic cell death, enabling Mtb clearance and antigen presentation to activate cell-mediated immune responses. We hypothesized that bacterial survival is aided by glycolysis-dependent macrophages, which can be targeted using a combination of metformin and 2DG to strengthen host immune responses. Using an in vitro model of guinea pig bone marrow derived macrophages under normal and high glucose conditions, we determined that both basal respiration and glycolytic activity increased after infection. When singly treated, metformin inhibited basal respiration while increasing glycolysis while 2DG inhibited both processes. In combination metformin and 2DG treatment inhibited basal respiration more effectively than metformin treatment alone and inhibited glycolysis as effectively as 2DG by itself. Efficacy of metformin-2DG treatment is dependent on high cellular glycolytic activity, a characteristic of granulomatous cells. Metformin-2DG treatment decreased cell survival 48 hours post-treatment by increasing apoptotic cell death and decreased Mtb survival more effectively than metformin or 2DG alone. We conclude that apoptotic induction of macrophages by metformin-2DG treatment may be a viable adjunct treatment to antimicrobial drugs to reduce bacterial burden and increase an effective host adaptive immune response

Lineage and Legacy : Horton Through the Ailey Lens, Then and Now

This written thesis includes my research and investigation into the ideologies of cultural relevance, equity and inclusion through the legacy and lineage of the Horton technique at The Ailey School. I examine the history of Lester Horton, Alvin Ailey and my experiences as an Ailey student, dancer and educator for nearly thirty years. I used this knowledge in the creation of my choreographic thesis offering, Roots and Routes . In this work I explored the historical and contextual framework of Horton at The Ailey School, while additionally giving voice to the use of this traditional, codified modern dance technique as a foundational tool in the creation of contemporary work

Informed Consent, Abortion, and Reproductive Autonomy

Abortion is an inimitable experience that poses a host of unique ethical and philosophical questions not generated by other medical procedures. In spite of a massive amount of literature discussing abortion, there is little theoretical work examining the relationship between abortion and informed consent. This is a problematic oversight because informed consent plays a prominent role in contemporary abortion practices. In an effort to address this lacuna, my dissertation explores the concept of informed consent as it functions within abortion discourse. Informed consent and abortion are both interdisciplinary terms and thus a robust critique of their intersection requires an interdisciplinary analysis. Therefore, I critically track the concept of informed consent across four unique discourses: traditional informed consent literature, Supreme Court rulings on abortion regulations, state-sponsored informed consent materials distributed to women seeking an abortion, and women’s firstperson narratives. As a contribution to feminist and bioethics scholarship, I argue that informed consent is a deeply inadequate concept in the context of abortion. Importantly, however, the reasons for this inadequacy change relative to the discourse in question. ! Thus, Chapters One, Two, Three, and Four each take as their focus a distinct discursive engagement of informed consent. In Chapter Five, I confront a series of questions generated by my interdisciplinary survey. In bridging the gaps between informed consent theory and abortion discourse, I demonstrate two important points. First, I illustrate how popular articulations of informed consent are ill-equipped to address the moral and medical issues particular to abortion. Secondly, I illuminate cases where the rhetoric of informed consent is, in fact, being used to undermine and jeopardize women’s reproductive autonomy. This dissertation concludes with a plea for a revised conception of informed consent within the abortion context, one that deploys the subjective standard of disclosure and recognizes the value of flexible dialogue between the woman and her abortion provider

Image and glory of God, glory of man : Evangelicals and Paul's hermeneutics of gender in 1 Corinthians 11:2-16

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Hierarchical Geographical Identifiers As An Indexing Technique For Geographic Information Retrieval

Location plays an ever increasing role in modern web-based applications. Many of these applications leverage off-the-shelf search engine technology to provide interactive access to large collections of data. Unfortunately, these commodity search engines do not provide special support for location-based indexing and retrieval. Many applications overcome this constraint by applying geographic bounding boxes in conjunction with range queries. We propose an alternative technique based on geographic identifiers and suggest it will yield faster query evaluation and provide higher search precision. Our experiment compared the two approaches by executing thousands of unique queries on a dataset with 1.8 million records. Based on the quantitative results obtained, our technique yielded drastic performance improvements in both query execution time and precision

Developing morale through training procedures

Thesis (M.B.A.)--Boston UniversityIndustrial management and psychology have been showing increasing interest in the understanding and developnent of worker morale. There has been considerable study" and research on the neaning, nature, causes, and developnent of morale. The importance of morale in industry- and society is constantly increasing. The amount of industrial training programs have been developing and increasing rapidly during the past several decades. Industrial management, personnel administration, and industrial ps,rchology have been active in the field of worker training and morale development. [TRUNCATED