Occupy as repair for returning: the case of the occupied hospital in Cariati

Within the repertoire of resistance, occupations constitute a form that has been historically articulated in a variety of modalities that differ in duration, space and purpose. From occupations of public spaces like squares and streets to ‘private’ spaces such as buildings, apartments and factories, their purpose depends on the specific kind of struggle at stake. Housing squats, social centres, recuperated factories are possibly the most durable examples of occupations. For our paper, we look at a not so common space for occupation: a hospital. Drawing on a series of semi-structured interviews and group discussions with members of the occupied hospital at Cariati, our intention is to reflect on the question of resistance as (re-)pair and highlight its creative and transformative potential over its oppositional stance. We propose to innovate the concept of resistance by looking at its connections with reparation and returns, looking at the occupation in Cariati as a potential for repairing a broken ecology and fostering reverse migration flows

Synthesis report: Social Economy education - a comparative analysis of UK, FR, ES, IT, EL

The synthesis report provides a comprehensive review of educational provisions on the Social Economy (SE) across 5 countries (UK, France, Spain, Italy and Greece) and sets the foundations for understanding the ways in which an SE programme could be designed to meet the needs of various relevant actors (in particular, educators, students and organisations). Our findings suggest that most programmes are quite general in terms of their focus on social economy or social entrepreneurship, with SE actors expressing an increasing appetite for more specialised courses which makes the development of new programmes with an explicit focus on social and solidarity economy strongly advisable. ‘Keeping a strong grounding in SE values whilst reaching out to a diversity of audiences’ Collaborations between Higher Education Institutions (HEI) and SE actors take different forms, yet they tend to be at the delivery stage rather than in the development of the programmes or the co-creation of knowledge, hence the role of SE actors in the designing and delivery of these programmes could be strengthened. Existing provisions do offer a range of innovative practices and any new programmes should build on, and expand, these practices. New programmes should provide a good balance between theory and practice, be flexible in their modes of delivery, create opportunities for networking, and have a strong grounding in SE values whilst being open enough to attract a variety of different audiences and adapt to different and changing environments

Social Economy education: State of the art and needs analysis report for UK

Social Economy education in the United Kingdom: ‘It should be in the DNA of all modules, in all disciplines’ Although there are many short courses on the SE, there is a shortage of HE programmes. But actors across the sectors are demanding Higher education provisions as well as stronger collaboration between Universities and SE organisations. ‘We need programmes designed to bring new, talented, people inside the cooperative sector.’ Despite the apparent difficulties to define social economy in the UK context and the variations across those self-identified as SE actors, there is a general emphasis on the ends pursued (emphasis on social mission) and a set of common values and principles underpinning organisations operating within the wider social economy sector. Universities need to strengthen their collaboration with SE actors; encourage critical thinking, nurture cultural awareness and support ethnic minority groups. There is a strong desire to extend collaborations between HE institutions and SE actors, yet we need to be mindful of existing scarcity of resources. Designing theoretically rigorous and practice-oriented programmes is in high demand. Finding the right balance between theory and practice is certainly a challenge, yet understanding the complexity of organisations operating in the wider social economy sector and helping graduates develop a range of skills and competencies alongside the cultivation of a distinctive, cooperative-driven and community-based, ethos is highly rated. Redefining ‘how people work and produce value’ and helping to ‘change the way that the economy works’, was considered to be among the top priorities of Universities and any programme related to social economy education

Social Economy education: State of the art report for France

Social and Solidarity Economy education in France: Strong HE provisions but the collaboration between HE and SE actors could be developed. France has a long history and tradition in the social economy, and the 2014 law has revitalised its influence and strongly contributed to the current institutionalisation of the sector bringing different forms of social organisations under one banner and setting the principles and criteria guiding it. This is also evident in the existing higher educational provisions in the country under the RIUESS network with over 20 UG courses, 40 PG courses and 19 ‘other’ courses available, perhaps the largest offering of social and solidarity programmes in Europe. All programmes have an explicit focus on social and solidarity economy offering a fine balance between theoretically rigorousness and practical skills. Programmes are modular over 1 or 2 years with the majority of them involving some period of work experience/internship aiming to help students acquire work experience and establish networks. Collaborations, particularly in the delivery of programmes, with SE actors is encouraged, yet is less clear from our findings whether these collaborations extend to the designing of the programmes too

Dopaminergic involvement in attention a novel animal model

1. 1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent.2. 2. Both drugs produced dose-related alterations in initial Y-maze behavior, consisting of significantly increased proportions of 2-arm entries.3. 3. This behavior has previously been shown to reflect an abnormal attentional process.4. 4. Thus DA activation may cause sensory perseveration.5. 5. The implications of this finding for DA theories of psychopathology is discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24570/1/0000852.pd

Protein Function Prediction by an ARTMAP Neural Network

Accurate prediction of protein functions solely from its amino acid sequence is 7 of paramount importance, particularly in the development of new drugs. An 8 ARTMAP neural network (NN) is employed to predict a protein’s function 9 based only on its amino-acid (AA) sequence. For our protein database, a Gene 10 Ontology-based search against the UniProt/SwissProt database for “DNA se-11 quence-specific binding proteins”. The search complement set was also re-12 trieved. For training and testing, various size datasets were generated. Datasets 13 were generated either by random sampling from the existing categories or by 14 classifying the proteins first into sub-groups based on a similarity measure and 15 then randomly sampling from each sub-group. Our NN’s performance with the 16 latter method performed better than with the former method in every size da-17 taset. Our NN has been successful in predicting the function of a protein from its 18 AA sequence by extracting a shared sequence-specific feature that is linked to 19 specific DNA binding proteins. This result is of major importance in structural 20 biology and biomedicine as it can provide a basis of the development of highly 21 specific tools for genome modification and gene therapy

Sructure determination of sc<i>Pvu</i>II by crystallographic and SAXS methods

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A Customized Light Sheet Microscope to Measure Spatio-Temporal Protein Dynamics in Small Model Organisms

We describe a customizable and cost-effective light sheet microscopy (LSM) platform for rapid three-dimensional imaging of protein dynamics in small model organisms. The system is designed for high acquisition speeds and enables extended time-lapse in vivo experiments when using fluorescently labeled specimens. We demonstrate the capability of the setup to monitor gene expression and protein localization during ageing and upon starvation stress in longitudinal studies in individual or small groups of adult Caenorhabditis elegans nematodes. The system is equipped to readily perform fluorescence recovery after photobleaching (FRAP), which allows monitoring protein recovery and distribution under low photobleaching conditions. Our imaging platform is designed to easily switch between light sheet microscopy and optical projection tomography (OPT) modalities. The setup permits monitoring of spatio-temporal expression and localization of ageing biomarkers of subcellular size and can be conveniently adapted to image a wide range of small model organisms and tissue samples.MR, GZ and AZ acknowledge funding from the Projects “Skin-DOCTor” Grant No. 1778 and “Neureka!” Grant No. LSF7-341 implemented under the "ARISTEIA" and "Supporting Postdoctoral Researchers" Actions respectively, of the "OPERATIONAL PROGRAMME EDUCATION AND LIFELONG LEARNING", (http://www.espa.gr/en/pages/staticOPEducationandLifelongLearning.aspx), which is co-funded by the European Social Fund and National Resources and from the EU Marie Curie Initial Training Network “OILTEBIA”, Grant No. PITNGA-2012-317526 (http://ec.europa.eu/research/mariecurieactions/, http://gdo.uc3m.es/oiltebia/index. php?option = com_content&view = frontpage). JR acknowledges support from EC FP7 CIG grant HIGHTHROUGHPUT TOMO PICIG12-GA-2012-333632, (http://cordis.europa.eu/projects/333632), and Spanish MINECO grant MESO-IMAGING FIS2013-41802-R, (https://sede.micinn.gob.es/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript