NODDI-SH: a computational efficient NODDI extension for fODF estimation in diffusion MRI

Diffusion Magnetic Resonance Imaging (DMRI) is the only non-invasive imaging technique which is able to detect the principal directions of water diffusion as well as neurites density in the human brain. Exploiting the ability of Spherical Harmonics (SH) to model spherical functions, we propose a new reconstruction model for DMRI data which is able to estimate both the fiber Orientation Distribution Function (fODF) and the relative volume fractions of the neurites in each voxel, which is robust to multiple fiber crossings. We consider a Neurite Orientation Dispersion and Density Imaging (NODDI) inspired single fiber diffusion signal to be derived from three compartments: intracellular, extracellular, and cerebrospinal fluid. The model, called NODDI-SH, is derived by convolving the single fiber response with the fODF in each voxel. NODDI-SH embeds the calculation of the fODF and the neurite density in a unified mathematical model providing efficient, robust and accurate results. Results were validated on simulated data and tested on \textit{in-vivo} data of human brain, and compared to and Constrained Spherical Deconvolution (CSD) for benchmarking. Results revealed competitive performance in all respects and inherent adaptivity to local microstructure, while sensibly reducing the computational cost. We also investigated NODDI-SH performance when only a limited number of samples are available for the fitting, demonstrating that 60 samples are enough to obtain reliable results. The fast computational time and the low number of signal samples required, make NODDI-SH feasible for clinical application

Alien Registration- Descoteaux, Albany (Biddeford, York County)

https://digitalmaine.com/alien_docs/1749/thumbnail.jp

The Fate of Napster: Digital Downloading Faces an Uphill Battle

First Diamond Multimedia, then MP3.com, now Napster. The recording industry, in a flurry to protect its copyrighted material, has waged an all-out battle against the dot-coms for the future of copyrighted music on the Internet. Since A&M Records, along with several other labels which comprise the Recording Industry Association of America (RIAA), filed suit against Napster, emotions have run high in the online community. Some have heralded this technology as a much-needed alternative to the strangling grasp of the major record labels; others view it as blatant theft of property. Students, musicians, computer programmers, trade organizations, and even the US government have voiced their opinions - all perhaps sensing that the outcome of the Napster litigation will have far-reaching consequences. Not only does the current battle over the fate of peer-to-peer technology promise to reshape the face of copyright law, it will also mark the future of the music industry, emerging technologies, and business models for years to come.The following iBrief describes the emergence of Napster\u27s peer-to-peer technology, the legal proceedings to date, and Napster\u27s defensive strategy, as well as the potential technological and cultural ramifications of the Napster cause celebr

The Fate of Napster: Digital Downloading Faces an Uphill Battle

First Diamond Multimedia, then MP3.com, now Napster. The recording industry, in a flurry to protect its copyrighted material, has waged an all-out battle against the dot-coms for the future of copyrighted music on the Internet. Since A&M Records, along with several other labels which comprise the Recording Industry Association of America (RIAA), filed suit against Napster, emotions have run high in the online community. Some have heralded this technology as a much-needed alternative to the strangling grasp of the major record labels; others view it as blatant theft of property. Students, musicians, computer programmers, trade organizations, and even the US government have voiced their opinions - all perhaps sensing that the outcome of the Napster litigation will have far-reaching consequences. Not only does the current battle over the fate of peer-to-peer technology promise to reshape the face of copyright law, it will also mark the future of the music industry, emerging technologies, and business models for years to come.The following iBrief describes the emergence of Napster\u27s peer-to-peer technology, the legal proceedings to date, and Napster\u27s defensive strategy, as well as the potential technological and cultural ramifications of the Napster cause celebr

Letter from Adrienne V. Descoteaux

A typed letter from Adrienne V. Descoteaux of Lewiston, Maine, to Mrs. Cyrus S. Kauffman, Publicity Chairman of the Portland College Club in Portland, Maine.https://digitalcommons.usm.maine.edu/michaud-1922-1938/1027/thumbnail.jp

The Future of Database Protection in U.S. Copyright Law

In the recent British Horseracing Board case, the English High Court signaled a return to the sweat of the brow standard of copyright protection. Although recent attempts have been made in the United States to protect databases under this standard, this iBrief argues that the information economy is wise to continuing protecting this data through trade secret, State misappropriation and contract law until legislation is passed

Mapping neuronal fiber crossings in the human brain

International audienceNew magnetic resonance imaging processing tools allow white-matter fiber bundles to be segmented and tracked in regions of high complexity