2,100 research outputs found
Decuplet Baryon Magnetic Moments in the Chiral Quark Model
We present calculations of the decuplet baryon magnetic moments in the chiral quark model. As input we use parameters obtained in qualitatively accurate fits to the octet baryon magnetic moments studied previously. The values found for the magnetic moments of and are in good agreement with experiments. We finally calculate the total quark spin polarizations of the decuplet baryons and find that they are considerably smaller than what is expected from the non-relativistic quark model
Sensing context: Inhibitory receptors on non-hematopoietic cells
Similar to immune cells, non-hematopoietic cells recognize microbial and endogenous threats. Their response to these stimuli is dependent on the environmental context. For example, intact intestinal epithelium expresses pattern recognition receptors (PRRs) but should tolerate commensal bacteria, while damaged epithelium should respond promptly to initiate an immune response. This indicates that non-hematopoietic cells possess mechanisms to sense environmental context and regulate their responses. Inhibitory receptors provide context sensing to immune cells. For instance, they raise the threshold for activation to prevent overzealous immune activation to harmless stimuli. Inhibitory receptors are typically studied on hematopoietic cells, but several of these receptors are expressed on non-hematopoietic cells. Here, we review evidence for the regulation of non-hematopoietic cells by inhibitory receptors, focusing on epithelial and endothelial cells. We explain that inhibitory receptors on these cells can sense a wide range of signals, including cell-cell adhesion, cell-matrix adhesion, and apoptotic cells. More importantly, they regulate various functions on these cells, including immune activation, proliferation, and migration. In conclusion, we propose that inhibitory receptors provide context to non-hematopoietic cells by fine tuning their response to endogenous or microbial stimuli. These findings prompt to investigate the functions of inhibitory receptors on non-hematopoietic cells more systematically
Hard X-ray detection of the high redshift quasar 4C 71.07
BATSE/OSSE observations of the high redshift quasar 4C 71.07 indicate that
this is the brightest and furthest AGN so far detected above 20 keV. BATSE
Earth occultation data have been used to search for emission from 4C 71.07 from
nearly 3 years of observation. The mean source flux over the whole period in
the BATSE energy range 20-100 keV is (13.2 +/- 1.06) x 10^(-11) erg cm^(-2)
s^(-1) corresponding to a luminosity of 2 x 10^(48) erg s^(-1). The BATSE light
curve over the 3 years of observations shows several flare-like events, one of
which (in January 1996) is associated with an optical flare (R=16.1) but with a
delay of 55 days. The OSSE/BATSE spectral analysis indicates that the source is
characterized by a flat power spectrum (Gamma about 1.1 - 1.3) when in a low
state; this spectral form is consistent within errors with the ASCA and ROSAT
spectra. This means that the power law observed from 0.1 to 10 keV extends up
to at least 1 MeV but steepens soon after to meet EGRET high energy data. BATSE
data taken around the January 1996 flare suggests that the spectrum could be
steeper when the source is in a bright state. The nuF-nu representation of the
source is typical of a low frequency peaked/gamma-ray dominated blazar, with
the synchrotron peak in the mm-FIR band and the Compton peak in the MeV band.
The BATSE and OSSE spectral data seem to favour a model in which the high
energy flux is due to the sum of the synchrotron self-Compton and the external
Compton contributions; this is also supported by the variability behaviour of
the source.Comment: 19 pages, LaTeX, plus 4 .ps figures. accepted by Astrophysical
Journa
Genome Symbols in the Triticeae (Poaceae)
A system for the application of nuclear genome symbols in the tribe Triticeae is proposed. It is based mainly on prevailing symbols. In agreement with this, the system uses individual upper case letters as symbols in the first place. Since the number of basic nuclear genomes in the Triticeae exceeds the number of single letters in the Roman alphabet, some basic genomes are designated with an upper case letter followed by a lower case letter, e.g. Ns for the genome of Psathyrostachys. Superscripts in small letters are used when modified versions of a basic genome are referred to, e.g. HP for the genome found in Hordeum pusillum. Unknown or equivocally identified genomes are designated by X followed by a lower case letter, e.g. Xu for Hordeum murinum. Underline of the relevant genome symbol can be used to indicate the origin of the cytoplasm
Inhibitory pattern recognition receptors
Pathogen- and damage-associated molecular patterns are sensed by the immune system's pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns. Hence, immune responses need to be context dependent, but it is not clear how context for molecular pattern recognition is provided. We discuss inhibitory receptors as potential counterparts to activating pattern recognition receptors. We propose a group of inhibitory pattern recognition receptors (iPRRs) that recognize endogenous and microbial patterns associated with danger, homeostasis, or both. We propose that recognition of molecular patterns by iPRRs provides context, helps mediate tolerance to microbes, and helps balance responses to danger signals
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