474 research outputs found
A three-sector endogenous growth model with combined technological change : the choice between basic innovations and quality improvements
Abstract not availableeconomics of technology ;
Effective pair potentials for spherical nanoparticles
An effective description for spherical nanoparticles in a fluid of point
particles is presented. The points inside the nanoparticles and the point
particles are assumed to interact via spherically symmetric additive pair
potentials, while the distribution of points inside the nanoparticles is taken
to be spherically symmetric and smooth. The resulting effective pair
interactions between a nanoparticle and a point particle, as well as between
two nanoparticles, are then given by spherically symmetric potentials. If
overlap between particles is allowed, the effective potential generally has
non-analytic points, but for each effective potential the expressions for
different overlapping cases can be written in terms of one analytic auxiliary
potential. Effective potentials for hollow nanoparticles (appropriate e.g. for
buckyballs) are also considered, and shown to be related to those for solid
nanoparticles. Finally, explicit expressions are given for the effective
potentials derived from basic pair potentials of power law and exponential
form, as well as from the commonly used London-Van der Waals, Morse,
Buckingham, and Lennard-Jones potential. The applicability of the latter is
demonstrated by comparison with an atomic description of nanoparticles with an
internal face centered cubic structure.Comment: 27 pages, 12 figures. Unified description of overlapping and
nonoverlapping particles added, as well as a comparison with an idealized
atomic descriptio
Efficient algorithms for rigid body integration using optimized splitting methods and exact free rotational motion
Hamiltonian splitting methods are an established technique to derive stable
and accurate integration schemes in molecular dynamics, in which additional
accuracy can be gained using force gradients. For rigid bodies, a tradition
exists in the literature to further split up the kinetic part of the
Hamiltonian, which lowers the accuracy. The goal of this note is to comment on
the best combination of optimized splitting and gradient methods that avoids
splitting the kinetic energy. These schemes are generally applicable, but the
optimal scheme depends on the desired level of accuracy. For simulations of
liquid water it is found that the velocity Verlet scheme is only optimal for
crude simulations with accuracies larger than 1.5%, while surprisingly a
modified Verlet scheme (HOA) is optimal up to accuracies of 0.4% and a fourth
order gradient scheme (GIER4) is optimal for even higher accuracies.Comment: 2 pages, 1 figure. Added clarifying comments. Accepted for
publication in the Journal of Chemical Physic
Critical bending point in the Lyapunov localization spectra of many-particle systems
The localization spectra of Lyapunov vectors in many-particle systems at low
density exhibit a characteristic bending behavior. It is shown that this
behavior is due to a restriction on the maximum number of the most localized
Lyapunov vectors determined by the system configuration and mutual
orthogonality. For a quasi-one-dimensional system this leads to a predicted
bending point at n_c \approx 0.432 N for an N particle system. Numerical
evidence is presented that confirms this predicted bending point as a function
of the number of particles N.Comment: 4 pages, 4 figure
Lyapunov Exponent Pairing for a Thermostatted Hard-Sphere Gas under Shear in the Thermodynamic Limit
We demonstrate why for a sheared gas of hard spheres, described by the SLLOD
equations with an iso-kinetic Gaussian thermostat in between collisions,
deviations of the conjugate pairing rule for the Lyapunov spectrum are to be
expected, employing a previous result that for a large number of particles ,
the iso-kinetic Gaussian thermostat is equivalent to a constant friction
thermostat, up to fluctuations. We also show that these deviations
are at most of the order of the fourth power in the shear rate.Comment: 4 pages, to appear in Rapid Comm., Phys. Rev.
Hopping dynamics for localized Lyapunov vectors in many-hard-disk systems
The dynamics of the localized region of the Lyapunov vector for the largest
Lyapunov exponent is discussed in quasi-one-dimensional hard-disk systems at
low density. We introduce a hopping rate to quantitatively describe the
movement of the localized region of this Lyapunov vector, and show that it is a
decreasing function of hopping distance, implying spatial correlation of the
localized regions. This behavior is explained quantitatively by a brick
accumulation model derived from hard-disk dynamics in the low density limit, in
which hopping of the localized Lyapunov vector is represented as the movement
of the highest brick position. We also give an analytical expression for the
hopping rate, which is obtained us a sum of probability distributions for brick
height configurations between two separated highest brick sites. The results of
these simple models are in good agreement with the simulation results for
hard-disk systems.Comment: 28 pages, 13 figure
Spatio-temporal correlations can drastically change the response of a MAPK pathway
Multisite covalent modification of proteins is omnipresent in eukaryotic
cells. A well-known example is the mitogen-activated protein kinase (MAPK)
cascade, where in each layer of the cascade a protein is phosphorylated at two
sites. It has long been known that the response of a MAPK pathway strongly
depends on whether the enzymes that modify the protein act processively or
distributively: distributive mechanism, in which the enzyme molecules have to
release the substrate molecules in between the modification of the two sites,
can generate an ultrasensitive response and lead to hysteresis and bistability.
We study by Green's Function Reaction Dynamics, a stochastic scheme that makes
it possible to simulate biochemical networks at the particle level and in time
and space, a dual phosphorylation cycle in which the enzymes act according to a
distributive mechanism. We find that the response of this network can differ
dramatically from that predicted by a mean-field analysis based on the chemical
rate equations. In particular, rapid rebindings of the enzyme molecules to the
substrate molecules after modification of the first site can markedly speed up
the response, and lead to loss of ultrasensitivity and bistability. In essence,
rapid enzyme-substrate rebindings can turn a distributive mechanism into a
processive mechanism. We argue that slow ADP release by the enzymes can protect
the system against these rapid rebindings, thus enabling ultrasensitivity and
bistability
Chaotic Properties of Dilute Two and Three Dimensional Random Lorentz Gases II: Open Systems
We calculate the spectrum of Lyapunov exponents for a point particle moving
in a random array of fixed hard disk or hard sphere scatterers, i.e. the
disordered Lorentz gas, in a generic nonequilibrium situation. In a large
system which is finite in at least some directions, and with absorbing boundary
conditions, the moving particle escapes the system with probability one.
However, there is a set of zero Lebesgue measure of initial phase points for
the moving particle, such that escape never occurs. Typically, this set of
points forms a fractal repeller, and the Lyapunov spectrum is calculated here
for trajectories on this repeller. For this calculation, we need the solution
of the recently introduced extended Boltzmann equation for the nonequilibrium
distribution of the radius of curvature matrix and the solution of the standard
Boltzmann equation. The escape-rate formalism then gives an explicit result for
the Kolmogorov Sinai entropy on the repeller.Comment: submitted to Phys Rev
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