Prepararse para la jubilación: el papel del apoyo social en la gestión de la ansiedad

La jubilación puede ser definida como una transición que implica el abandono de un rol laboral y, por consiguiente, esto requiere la capacidad de reestructurar el sistema de funciones y actividades personales. Este estudio incluyó 250 empleados de dos administraciones públicas italianas de más de 48 años de edad, con el objetivo de entender cómo durante el tiempo previo a la jubilación el apoyo social recibido por fuentes laborales y extra-laborales puede influir en la ansiedad hacia su jubilación y cómo la última modula la edad a la que se desea jubilarse. Los resultados obtenidos mediante análisis de modelos de ecuaciones estructurales LISREL muestran cómo el apoyo social del superior y la implicación con el trabajo aumentarán la ansiedad debida a la pérdida de la identidad social, mientras que el apoyo de los miembros de la familia tiende a reducir el tamaño de la ansiedad anterior al retiro de la vida laboral. El apoyo de los amigos reduce la ansiedad ante la anticipación de exclusión social. Por lo último, la ansiedad parece influir la edad en la que se desea jubilarse. Retirement can be considered a transition that implies losing one's work role and therefore there is a need to be capable of restructuring one's systems of personal roles and activities. This study used a sample of 250 employees of public administration aged over 48 to find the extent to which work and non-work sources of social support can affect anxiety during the period of preparation for retirement. In addition, the study explored the relation between social support and intended retirement age. LISREL structural equation model analysis shows that supervisor's social support and job involvement increase the anxiety resulting from identity loss, whereas family social support decreases this anxiety. Moreover, friends' social support reduces the anxiety owing to anticipated social exclusion. Finally, retirement related anxiety predicts intended retirement age

Support from Teaching Staff and Self-efficacy as Determinants of Students' Perceived Employability: a Longitudinal study

[EN] Perceived employability acquires, for university students, growing importanceto deal with occupational uncertainty. This study examines how teaching inuniversity influences perceived employability in a sample of Italian final-yearuniversity students. We draw on Conservation on Resources Theory andCareer self-management model to hypothesise a positive impact of supportfrom teaching staff on students' perceived employability. We also contend thatstudents' self-efficacy mediates the relationship between support from teachingstaff and perceived employability. One hundred fifty-one university studentscompleted a survey three times over 10 months. The results confirm thatsupport from teaching staff enhances students' perceived employabilitydirectly and indirectly by shaping students' self-efficacy. Our findings confirmthe role of university teachers and their didactical practice to equip theirstudents with career resources.Petruzziello, G.; Mariani, MG.; Guglielmi, D.; Chiesa, R. (2021). Support from Teaching Staff and Self-efficacy as Determinants of Students' Perceived Employability: a Longitudinal study. En 7th International Conference on Higher Education Advances (HEAd'21). Editorial Universitat Politècnica de València. 1079-1086. https://doi.org/10.4995/HEAd21.2021.12957OCS1079108

Invest in Your Mental Health, Support Your Career. Exploring the Impact of Mental Health Activities on Movement Capital and the Mediating Role of Flourishing and Career Engagement during the Transition to Work

The current theorising of career self-management advocates that personal resources that support an adaptive transition to work are bound to individual agency. Yet, research still needs to enrich the empirical exploration of how behaviours in personal life affect careers. For this reason, we explored the impact of mental-health activities—a group of self-help activities that people can perform to increase their mental health—on movement capital among Italian new entrants in the labour market. We also explored a mechanism underlying this relationship by testing the mediating role of flourishing and career engagement. We collected data from 229 Italian university students and recent graduates through an online questionnaire. Contrary to our expectations, we found no significant direct relationship between mental-health activities and movement capital, yet the results supported an indirect relationship. The findings contribute to existing evidence about how personal life behaviours affect career self-management and advance the understanding of the role of mental health activities. This work suggests ways to encourage engagement in self-help behaviours and implement public and higher education interventions to foster these behaviours’ benefits for an adaptive transition to work

It takes more than agency: Linking support from teaching staff, career engagement, and movement capital among university students

Introduction: Career self-management behaviours are key to overcoming the challenges of entry into the labour market. Combining the Conservation of Resources and Career Self-management theories, this study delves into the concept of Career Engagement among Italian University students by examining its relationship with Support from teaching Staff and Movement Capital. We hypothesised a mediation model in which Support from Teaching Staff predicts Career Engagement which, in turn, fosters Movement Capital. As the pandemic led to the adoption of online learning solutions, we also explored whether and how the interaction between teachers and students during online classes moderates the said mediation relationship. Methods and results: We collected data from 276 Italian University students through an online questionnaire. Results supported the mediation hypothesis, corroborating the mediating role of Career Engagement. We also observed that this relationship is stronger at medium and higher levels of online interaction between teachers and students. Discussion: Findings contribute to existing evidence about the role of Career Engagement in facilitating career resources’ acquisition and extend the understanding of its contextual antecedents in Higher Education contexts. Results also align with the importance attributed to interaction in online learning environments. This work suggests ways to encourage career behaviours in Higher Education and equip prospective labour market entrants with career resources

In Vitro Reconstructed Human Epithelial Models for Microbial Infection Research: Why Do We Need them?

In the last 50 years, the Replacement, Reduction and Refinement principles have become a framework for conducting high quality academic, pre-clinical, clinical and industrial research experimentation studies, in order to respond to the European Union legislative demand of alternatives to animal-based experimentation, often difficult to translate to human applications, expensive and not ethically approved. Thanks to the improvement of cellular isolation protocols, culture and co-culture conditions, together with the increased clinical demand, several novel in vitro three-dimensional tissue engineered human epithelial models, able to create sophisticate pre-clinical tests and produce results more reliable than the traditional bi-dimensional flat cell culture systems, have been developing also for microbial infection research purposes

EVALUATION OF THE INTERACTION AMONG HPV16 E6 AND E7 ONCOPROTEINS AND THE DNA DAMAGE SENSOR 53BP1 IN 2D AND 3D EPITHELIAL CULTURES BY THE PROXIMITY LIGATION ASSAY

INTRODUCTION. Human papillomaviruses (HPV) group several viruses able to infect squamous stratified epithelia and cause benign papillomas, warts and anogenital lesions. They also correlate to oropharyngeal and anogenital malignancies, mainly promoted by the high risk (HR) \u3b1-HPV16 E6E7 oncoproteins. Despite scientific progresses and the development of vaccines, these tumors are still common and represent one of the major causes of women\u2019s death. Host\u2019s cell replication fidelity depends by the DNA Damage Response (DDR). Unlike from other DNA viruses, HR-HPVs encourage cells proliferation without inactivating the DDR: the mechanisms at the basis haven\u2019t been clarified yet. During HPV16 infection, E6 binds and degrades p53 through the E6AP LXXLL domain. Similarly, E7 competes with E2F1-pRb interaction, thus inactivating pRb, and promoting the linking the pRb-like proteins CBP/p300 and p107, that also harbor a LXXLL sequence. Unfortunately, E6 E7 role in the DDR activation is not elucidated yet. EXPERIMENTAL MODEL. To gain new information, we reproduced an in vitro 3D HPV16-E6E7 infected epithelium, already characterized for HPVs studies, and checked for cellular and viral markers, among them HPV16E6E7 oncoproteins and the double strand breaks (DSB) sensor 53BP1; we then made a Co-IF for E6 and E7 with 53BP1. Since E6 and E7 both interact with LXXLL containing proteins, we analyzed 53BP1 BRCT2 domain and we explored the binding hypothesis via the in situ PLA technique in 2D in CaSki and E6E7HPV16 keratinocytes and in the 3D model. RESULTS. The in vitro infected epithelium resembles the in vivo tissue. E6E7HPV16, both in basal and differentiated strata, induce a 53BP1 increase in nuclear foci. After highlighting E6 and E7 co-expression with 53BP1 and a LKVLL sequence within the 53BP1 BRCT2 domain, we demonstrated the binding in all the employed cellular models. CONCLUSION. Our results add new information on HPV16 oncoproteins capability in overcome cellular defense strategies

Positive aging in demanding workplaces: The gain cycle between job satisfaction and work engagement

Nowadays organizations have to cope with two related challenges: maintaining an engaged and highly performing workforce and, at the same time, protecting and increasing employees' well-being and job satisfaction under conditions of a generalized increase of job demand, in an increasingly growing older population. According to the motivational process of the JD-R model, a work environment with many organizational resources will foster work engagement, which in turn will increase the likelihood of positive personal and organizational outcomes, such as job satisfaction, performance, and intention to stay. However, it is not clear how this motivational process could work in different age cohorts, as older workers may have different priorities to those of younger colleagues. Postulating the existence of a gain-cycle in the relationship between work engagement and outcomes, in this study we tested a longitudinal moderated mediation model in which job satisfaction increases over time through an increment in work engagement. We hypothesized that this process is moderated by job demand and aging. We collected data in public administrations in Northern Italy in order to measure work engagement and job satisfaction. 556 workers aged between 50 and 64 replied to the survey twice (the first time and 8 months later). The findings confirmed a moderated mediation model, in which job satisfaction at time 1 increased work engagement, which in turn fostered job satisfaction 8 months later, confirming the hypothesized gain-cycle. This relationship was shown to be moderated by the joint influence of job demand intensity and age: higher job demands and younger age are related to the maximum level of level gain cycle, while the same high level of job demands, when associated with older age, appears unable to stimulate a similar effect. The results confirm that, on one hand, older workers cannot be seen as a homogeneous group and, on the other hand, the importance of considering the role played by the gain cycle of resources. Our findings show that age matters, and that greater consideration should be devoted to age differences in order to design appropriate human resources practices that foster work engagement and satisfaction

Coping With Negative Stereotypes Toward Older Workers: Organizational and Work-Related Outcomes

The current study aims to test a moderated-mediation model in which occupational self-efficacy determines the indirect effect of negative stereotypes about older workers in the organization both on psychological engagement in the work domain and on attitudes toward development opportunities through identification with the company. The survey involved 1,501 Italian subjects aged over 50 who were employed by a major large-scale retailer. Consistently with the Social Identity Theory and the Social Exchange Theory, results showed that the perception of negative stereotypes about older workers in the organization is associated with low identification with the company and, subsequently, with poor psychological engagement in the work domain and with attitudes indicating very little interest in development opportunities. In addition, this association was found to be stronger in older workers with higher and medium levels of occupational self-efficacy. These findings suggest that organizations should discourage the dissemination of negative stereotypes about older workers in the workplace because they may lead to older workers’ disengagement from the work domain and their loss of interest in development opportunities

The Effect of Age and Sampling Site on the Outcome of Staphylococcus aureus Infection in a Rabbit (Oryctolagus cuniculus) Farm in Italy

Abstract: A study in an intensive Italian rabbit farm was carried out to assess the eect of age category and anatomical site on detection of S. aureus and to describe the diversity of spa-types within farm, including workers. On 400 rabbits of dierent age, 2066 samples from the ear, nose, axilla, groin, perineum and lesions were analyzed and 595 S. aureus were isolated. In total, 284 (71.0%) were colonized by S. aureus in at least one anatomical site and 35 animals (8.8%) had lesions. S. aureus prevalence was higher in adults than other age categories. Ear (29.4%) and nose (27.2%) were the most frequently colonized sites. The presence of lesions due to S. aureus was strongly associated with the colonization of at least one body site and the risk of lesions was proportionate to the number of sites colonized by S. aureus. In addition, a genotypic characterization was performed for 96 S. aureus strains randomly selected. All isolates resulted as low-virulence methicillin-sensitive-Staphylococcus aureus (LV-MSSA). Five dierent clonal lineages were found: spa-t2802, the most frequently detected (53.1%), also in human samples; spa-t491 (38.5%); spa-t094; t605; and spa-t2036. Strains t094, t491 and t2036 have not been isolated in Italy before