2,594 research outputs found

    My Evolving Program for Negro Freedom

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    This autobiographical essay, published in 1944, defines freedom for Negroes and identifies the paths taken by Du Bois to achieve this freedom

    Differences between Men and Women in Their Response to Heat and Cold

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    Literatura e resistência: a força da quebrada diante dos silenciamentos do campo literário

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    Based on the survey conducted by Regina Dalcastagnè about the profile of the Brazilian writer, intend to problematize the silencing and criteria of eligibility of the literary field, which culminate in a literary production mostly white, heterosexual, and male. This prevalence results in an adjectivation of literature that does not fit this pattern – female, black, indigenous, LGBT, marginal and peripheral literature –, insofar as canonicais literature is assumed to be universal. Dialoguing with the problematizations raised by Dalcastagnè, in the second moment, the article will work with the resistance movements of marginal literature, which opens its doors despite the publishing circuit of the big publishing houses. Will be analyzed two saraus of emblematic importance in this process of decentralization, Cooperifa in São Paulo and Coletivoz in Belo Horizonte, which circulate the strength of marginal literature in their writings.A partir do levantamento realizado por Regina Dalcastagnè sobre o perfil do escritor brasileiro, pretende-se problematizar os silenciamentos e critérios de elegibilidade do campo literário, que culminam numa produção literária majoritariamente branca, heterossexual e masculina. Esta prevalência resulta numa adjetivação de literaturas que não se enquadram nesse padrão -literatura feminina, negra, indígena, LGBT, marginal e periférica-, na medida em que se pressupõe como universal a literatura canônica. Dialogando com as problematizações levantadas por Dalcastagnè, no segundo momento, o artigo trabalhará com os movimentos de resistência da literatura marginal, que abre vão a despeito do circuito de publicação das grandes editoras. Serão analisados brevemente dois saraus de importância emblemática nesse processo de descentralização, a Cooperifa em São Paulo e o Coletivoz em Belo Horizonte, que fazem circular a força da literatura marginal em suas escrevivências.

    The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference

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    The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is unknown

    Testing the Waters: Blogging for User Needs Analysis, Information Access, and Building a Community of Practitioners

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    ABSTRACT This panel session will focus on three strategies for using blogs to improve access to collections, understand information needs of those searching the collections, and build communities of practice with information professionals serving similar user groups. Three presenters will share their experiences, goals, methods, and results. A facilitated discussion with the audience will follow the presentations and allow attendees to brainstorm on possible uses of blogging outside the box to reach the goals of their current projects or initiatives that they are hoping to undertake in the near future

    Displasia Ectodérmica Anhidrótica

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    El presente trabajo tiene por finalidad difundir el caso clínico de una displasia ectodérmica anhidrótica con importantes manifestaciones bucales. Esta enfermedad se caracteriza por la ausencia o la disminución del pelo, dientes, uñas, glándulas sudoríparas y sebáceas, anomalías de la nariz, pabellones auriculares, labios y sistema dentario, signos que acompañan a trastornos del sistema nervioso central.La displasia ectodérmica anhidrótica, se trata de un síndrome heredo familiar, transmitido como un rasgo recesivo ligado al cromosoma X, que afecta en el 90% de los casos a los varones. El resto corresponde a mujeres portadoras que presentan sintomatología escasa.El reconocimiento de las manifestaciones clínicas generales y bucales nos permitirá instituir una conducta terapéutica adecuada

    Validation of test performance characteristics and minimal clinically important difference of the 6-minute walk test in patients with idiopathic pulmonary fibrosis

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    SummaryBackgroundThe 6-minute walk test distance (6MWD) has been shown to be a valid and responsive outcome measure in patients with idiopathic pulmonary fibrosis (IPF). The analyses were based, however, on a single phase 3 trial and require validation in an independent cohort.ObjectiveTo confirm the performance characteristics and estimates of minimal clinically important difference (MCID) of 6MWD in an independent cohort of patients with IPF.MethodsPatients randomized to placebo in the phase 3 CAPACITY trials who had a baseline 6MWD measurement were included in these analyses. The 6MWD and other functional parameters (lung function, dyspnea, and health-related quality of life) were measured at baseline and 24-week intervals. Validity and responsiveness were examined using Spearman correlation coefficients. The MCID was estimated using distribution- and anchor-based methods.ResultsThe analysis comprised 338 patients. Baseline 6MWD was significantly correlated with lung function measures, patient-reported outcomes, and quality-of-life measures (validity). Compared with baseline 6MWD, change in 6MWD (responsiveness) showed stronger correlations with change in lung function parameters and quality-of-life measures. Dyspnea measured by the University of California San Diego Shortness of Breath Questionnaire showed the strongest correlations with 6MWD (baseline: coefficient −0.35; 48-week change: coefficient −0.37; both p < 0.001). The distribution-based analyses of MCID using standard error of measurement yielded an MCID of 37 m, and distribution-based analyses by effect size resulted in 29.2 m. The MCID by anchor-based analysis using criterion referencing (health events of hospitalization or death) was 21.7 m.ConclusionsThe 6MWD is a valid and responsive clinical endpoint, which provides objective and clinically meaningful information regarding functional status and near-term prognosis. These results confirm previous findings in an independent cohort of patients with IPF
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