1,235 research outputs found
Matrix metalloproteinase activities and their relationship with collagen remodelling in tendon pathology
Our aim was to correlate the activity of matrix metalloproteinases (MMPs) with denaturation and the turnover of collagen in normal and pathological human tendons. MMPs were extracted from ruptured supraspinatus tendons (n=10), macroscopically normal (‘control’) supraspinatus tendons (n=29) and normal short head of biceps brachii tendons (n=24). Enzyme activity was measured using fluorogenic substrates selective for MMP-1, MMP-3 and enzymes with gelatinolytic activity (MMP-2, MMP-9 and MMP-13). Collagen denaturation was determined by a-chymotrypsin digestion. Protein turnover was determined by measuring the percentage of d-aspartic acid (% d-Asp). Zymography was conducted to identity specific gelatinases. MMP-1 activity was higher in ruptured supraspinatus compared to control supraspinatus and normal biceps brachii tendons (70.9, 26.4 and 11.5 fmol/mg tendon, respectively;
Molecular and mass spectroscopic analysis of isotopically labeled organic residues
Experimental studies aimed at understanding the evolution of complex organic molecules on interstellar grains were performed. The photolysis of frozen gas mixtures of various compositions containing H2O, CO, NH3, and CH4 was studied. These species were chosen because of their astrophysical importance as deducted from observational as well as theoretical studies of ice mantles on interstellar grains. These ultraviolet photolyzed ices were warmed up in order to produce refractory organic molecules like the ones formed in molecular clouds when the icy mantles are being irradiated and warmed up either by a nearby stellar source or impulsive heating. The laboratory studies give estimates of the efficiency of production of such organic material under interstellar conditions. It is shown that the gradual carbonization of organic mantles in the diffuse cloud phase leads to higher and higher visual absorptivity - yellow residues become brown in the laboratory. The obtained results can be applied to explaining the organic components of comets and their relevance to the origin of life
Phase space spinor amplitudes for spin 1/2 systems
The concept of phase space amplitudes for systems with continuous degrees of
freedom is generalized to finite-dimensional spin systems. Complex amplitudes
are obtained on both a sphere and a finite lattice, in each case enabling a
more fundamental description of pure spin states than that previously given by
Wigner functions. In each case the Wigner function can be expressed as the star
product of the amplitude and its conjugate, so providing a generalized Born
interpretation of amplitudes that emphasizes their more fundamental status. The
ordinary product of the amplitude and its conjugate produces a (generalized)
spin Husimi function. The case of spin-\half is treated in detail, and it is
shown that phase space amplitudes on the sphere transform correctly as spinors
under under rotations, despite their expression in terms of spherical
harmonics. Spin amplitudes on a lattice are also found to transform as spinors.
Applications are given to the phase space description of state superposition,
and to the evolution in phase space of the state of a spin-\half magnetic
dipole in a time-dependent magnetic field.Comment: 19 pages, added new results, fixed typo
Channel kets, entangled states, and the location of quantum information
The well-known duality relating entangled states and noisy quantum channels
is expressed in terms of a channel ket, a pure state on a suitable tripartite
system, which functions as a pre-probability allowing the calculation of
statistical correlations between, for example, the entrance and exit of a
channel, once a framework has been chosen so as to allow a consistent set of
probabilities. In each framework the standard notions of ordinary (classical)
information theory apply, and it makes sense to ask whether information of a
particular sort about one system is or is not present in another system.
Quantum effects arise when a single pre-probability is used to compute
statistical correlations in different incompatible frameworks, and various
constraints on the presence and absence of different kinds of information are
expressed in a set of all-or-nothing theorems which generalize or give a
precise meaning to the concept of ``no-cloning.'' These theorems are used to
discuss: the location of information in quantum channels modeled using a
mixed-state environment; the (classical-quantum) channels introduced by
Holevo; and the location of information in the physical carriers of a quantum
code. It is proposed that both channel and entanglement problems be classified
in terms of pure states (functioning as pre-probabilities) on systems of parts, with mixed bipartite entanglement and simple noisy channels belonging
to the category , a five-qubit code to the category , etc.; then by
the dimensions of the Hilbert spaces of the component parts, along with other
criteria yet to be determined.Comment: Latex 32 pages, 4 figures in text using PSTricks. Version 3: Minor
typographical errors correcte
Minimum Decision Cost for Quantum Ensembles
For a given ensemble of independent and identically prepared particles,
we calculate the binary decision costs of different strategies for measurement
of polarised spin 1/2 particles. The result proves that, for any given values
of the prior probabilities and any number of constituent particles, the cost
for a combined measurement is always less than or equal to that for any
combination of separate measurements upon sub-ensembles. The Bayes cost, which
is that associated with the optimal strategy (i.e., a combined measurement) is
obtained in a simple closed form.Comment: 11 pages, uses RevTe
Phenomenological approach to the critical dynamics of the QCD phase transition revisited
The phenomenological dynamics of the QCD critical phenomena is revisited.
Recently, Son and Stephanov claimed that the dynamical universality class of
the QCD phase transition belongs to model H. In their discussion, they employed
a time-dependent Ginzburg-Landau equation for the net baryon number density,
which is a conserved quantity. We derive the Langevin equation for the net
baryon number density, i.e., the Cahn-Hilliard equation. Furthermore, they
discussed the mode coupling induced through the {\it irreversible} current.
Here, we show the {\it reversible} coupling can play a dominant role for
describing the QCD critical dynamics and that the dynamical universality class
does not necessarily belong to model H.Comment: 13 pages, the Curie principle is discussed in S.2, to appear in
J.Phys.
Drag in paired electron-hole layers
We investigate transresistance effects in electron-hole double layer systems
with an excitonic condensate. Our theory is based on the use of a minimum
dissipation premise to fix the current carried by the condensate. We find that
the drag resistance jumps discontinuously at the condensation temperature and
diverges as the temperature approaches zero.Comment: 12 pages, 1 Figure, .eps file attache
Observations of coarsening of air voids in a polymer–highly-soluble crystalline matrix during dissolution
Time resolution of the plastic scintillator strips with matrix photomultiplier readout for J-PET tomograph
Recent tests of a single module of the Jagiellonian Positron Emission
Tomography system (J-PET) consisting of 30 cm long plastic scintillator strips
have proven its applicability for the detection of annihilation quanta (0.511
MeV) with a coincidence resolving time (CRT) of 0.266 ns. The achieved
resolution is almost by a factor of two better with respect to the current
TOF-PET detectors and it can still be improved since, as it is shown in this
article, the intrinsic limit of time resolution for the determination of time
of the interaction of 0.511 MeV gamma quanta in plastic scintillators is much
lower. As the major point of the article, a method allowing to record
timestamps of several photons, at two ends of the scintillator strip, by means
of matrix of silicon photomultipliers (SiPM) is introduced. As a result of
simulations, conducted with the number of SiPM varying from 4 to 42, it is
shown that the improvement of timing resolution saturates with the growing
number of photomultipliers, and that the 2 x 5 configuration at two ends
allowing to read twenty timestamps, constitutes an optimal solution. The
conducted simulations accounted for the emission time distribution, photon
transport and absorption inside the scintillator, as well as quantum efficiency
and transit time spread of photosensors, and were checked based on the
experimental results. Application of the 2 x 5 matrix of SiPM allows for
achieving the coincidence resolving time in positron emission tomography of
0.170 ns for 15 cm axial field-of-view (AFOV) and 0.365 ns
for 100 cm AFOV. The results open perspectives for construction of a
cost-effective TOF-PET scanner with significantly better TOF resolution and
larger AFOV with respect to the current TOF-PET modalities.Comment: To be published in Phys. Med. Biol. (26 pages, 17 figures
Mean Field Calculations of Bose-Einstein Condensation of 7Li Atoms In a Harmonic Trap
A self-consistent mean-field theory for bosons for T>0 is used to reconcile
predictions of collapse with recent observations of Bose-Einstein condensation
of 7Li. Eigenfunctions of a (non-separable) Hamiltonian that includes the
anisotropic external trap field and atom-atom interactions are obtained by an
iteration process. A sum over the Bose distribution, and the ``alternating
direction implicit'' algorithm are used. Near Tc, the ensemble exhibits a
localized condensate composed of atoms in the few lowest states. For lower T,
numerical instability indicates collapse to a more dense phase.Comment: 11 pages + 4 figure
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