Entangled coherent states and squeezing in N trapped ions

We consider a resonant bichromatic excitation of N trapped ions that generates displacement and squeezing in their collective motion conditioned to their ionic internal state, producing eventually Scrhodinger cat states and entangled squeezing. Furthermore, we study the case of tetrachromatic illumination or producing the so called entangled coherent states in two motional normal modes.Comment: 4 Revtex pages, no figures. To appear in Proceedings of "Mysteries, Puzzles and Paradoxes in Quantum Mechanics", Garda Lake, Italy (2001

Time Consistent Pareto Solutions in Common Access Resource Games with Asymmetric Players

In the analysis of equilibrium policies in a dierential game, if agents have different time preference rates, the cooperative (Pareto optimum) solution obtained by applying the Pontryagin's Maximum Principle becomes time inconsistent. In this work we derive a set of dynamic programming equations (in discrete and continuous time) whose solutions are time consistent equilibrium rules for N-player cooperative dierential games in which agents dier in their instantaneous utility functions and also in their discount rates of time preference. The results are applied to the study of a cake-eating problem describing the management of a common property exhaustible natural resource. The extension of the results to a simple common property renewable natural resource model in innite horizon is also discussed.cooperative solutions, dierential games, asymmetric players, resource games, time-inconsistency, heterogeneous discount rates

Heterogeneous discounting in consumption-investment problems. Time consistent solutions

In this paper we analyze a stochastic continuous time model in finite horizon in which agents discount the instantaneous utility function and the final function at constant but different instantaneous discount rates of time preference. Within this context we can model problems in which, when the time t approaches to the final time, the valuation of the final function increases compared with previous valuations in a way that cannot be explained by using a unique constant or a variable discount rate. We derive a dynamic programming equation whose solutions are time-consistent Markov equilibria. For this class of time preferences, we study the classical consumption and portfolio rules model (Merton, 1971) for CRRA and CARA utility functions for time- consistent agents, and we compare the different equilibria with the time-inconsistent solutions. The introduction of stochastic terminal time is also discussed.dynamic programming, consumption and portfolio rules, heterogeneous discounting, time consistency

Reliable teleportation in trapped ions

We study a method for the implementation of a reliable teleportation protocol (theoretically, 100% of success) of internal states in trapped ions. The generation of the quantum channel (any of four Bell states) may be done respecting technical limitations on individual addressing and without claiming the Lamb-Dicke regime. An adequate Bell analyzer, that transforms unitarily the Bell basis into a completely disentangled one, is considered. Probable sources of error and fidelity estimations of the teleportation process are studied. Finally, we discuss experimental issues, proposing a scenario in which the present scheme could be implemented.Comment: 8 Latex pages with five (ps,eps) figures included (EPJ style also included). Accepted for publication in European Physical Journal

Os resultados de pesquisa nas mãos do público infanto-juvenil por meio dos jogos interativos.

CBBD

A comparative study of image processing thresholding algorithms on residual oxide scale detection in stainless steel production lines

The present work is intended for residual oxide scale detection and classification through the application of image processing techniques. This is a defect that can remain in the surface of stainless steel coils after an incomplete pickling process in a production line. From a previous detailed study over reflectance of residual oxide defect, we present a comparative study of algorithms for image segmentation based on thresholding methods. In particular, two computational models based on multi-linear regression and neural networks will be proposed. A system based on conventional area camera with a special lighting was installed and fully integrated in an annealing and pickling line for model testing purposes. Finally, model approaches will be compared and evaluated their performance..Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

HPLC-MS analysis of Atorvastatin and its metabolites in plasma and prostate cancer tissue

Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017The aim of the proposed work was to develop and validate a simple and sensitive method for the analysis of atorvastatin (ATV) and its metabolites in human plasma and in the tissue (prostate) using liquid chromatography-tandem mass spectrometry. 57 samples of plasma and tissue from prostate cancer patients, treated with atorvastatin, were analyzed. Mass spectrometry detection was carried out in positive electrospray ionization mode, with multiple reaction monitoring scan. The assay exhibited a linear dynamic range from 0,25-250 ng/mL and the calibration curves for the analytes were linear (R20.8997). The accuracy (86.2-111.8%), matrix effect (80.6-94.71%), overall recovery (74.7-81.8%) were another parameters evaluated based on guidelines of the European Medicines Agency (EMA) and Food and drug Administration (FDA). The validated method was successfully applied to analyze human plasma samples for application in pharmacokinetic, bioavailability or bioequivalence studies. Despite ATV was detected in prostate, further studies are still required to conclude the mechanism how the drug can go into the tissue and the way it can lead to benefits in prostate cancer.O objetivo do trabalho proposto foi desenvolver e validar um método simples e sensível para a análise e deteção da atorvastatina (ATV) e respetivos metabolitos presentes no plasma humano e no tecido (próstata), utilizando a cromatografia líquida de alta eficiência acoplada à espectrometria de massa (HPLC-MS/MS). 57 amostras de plasma e tecido provenientes de pacientes com cancro de próstata foram analisadas, todos eles a realizar tratamento com atorvastatina. A deteção de espectrometria de massa foi realizada através de ionização por electrospray (modo positivo), com monitoramento de múltiplas reações. Neste ensaio obteve-se um intervalo linear de concentrações entre 0,25-250 ng/mL e as curvas de calibração para os analitos foram igualmente lineares e aceitáveis (R20.8997). A exactidão (86.2-111.8 %), o efeito da matriz (80.6-94.71 %), a taxa de recuperação (74.7-81.8 %) foram outros parâmetros avaliados, baseados em guidelines da Agência Europeia do Medicamento (EMA). O método validado tem vindo a ser aplicado com sucesso, com o intuito de analisar amostras de plasma humano para aplicação em estudos de farmacocinética, biodisponibilidade ou bioequivalência. Apesar da atorvastatina ter sido detetada na próstata, ainda são necessários estudos adicionais para concluir acerca do mecanismo pelo qual o fármaco consegue atravessar o tecido e qual o seu impacto e possível benefício em doentes com cancro da próstata

Población y áreas lingüísticas en El Salvador; 1772.

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