Myocardium tissue changes caused by electrical transthoracic discharges in rats

<p>Abstract</p> <p>Background</p> <p>Cardiomyocytes cytoarchitecture changes caused by transthoracic countershocks have been focused recently. We aimed to evaluate the effects of electrical discharge application in the mitochondria structure in atrial myocardium of rats.</p> <p>Methods</p> <p>An electrical cardioverter was adapted to small rodent animals for our research. Electrical discharges were applied to the precordial region of 30 albino rats: (1) control group - animals that remained on resting period and were afterwards sacrificed; (2) electrical discharge group - animals that remained on resting period, followed by ten electrical discharges of 300 mV and sacrificed, and; (3) electrical post-discharge group - animals that remained on a resting period and received ten electrical discharges like the electrical discharge group, but were sacrificed seven days subsequently. We examined liver, adrenal and left atrium tissue fragments of the three groups.</p> <p>Results</p> <p>It was observed in control and post-discharge groups a normal cellular structure aspect with preserved architecture of cardiomyocytes and continuous sarcoplasmic membrane integrity. On the other hand, cardiac muscle fibers with mitochondrial edema and lysis occurred in the discharge group. Glycogen and adrenal lipids were not depleted in all groups.</p> <p>Conclusion</p> <p>These data suggest that transthoracic electrical discharges induce mitochondrial injuries in atrial cardiac cells of rats.</p

COMPONENTES NO CONTEXTO DO AGRONEGÓCIO CAFÉ EM RONDÔNIA: ABORDAGEM DAS CARACTERÍSTICAS BÁSICAS

Este artigo analisa o sistema agroindustrial (SAG) do café em Rondônia como um relevante segmento que gera emprego e renda, riqueza e divisas para o Estado e para os diversos setores da atividade econômica e, que contribui de forma efetiva para o desenvolvimento sócio-econômico local. Examinam-se as principais características relacionadas desde a participação efetiva de instituições de assistência técnica e científica na orientação e apoio ao desenvolvimento do setor cafeeiro até a abordagem de algumas alternativas para o seu cultivo e manejo que, representam oportunidades no agronegócio café, com o fito de analisar e destacar a sua importância para o desenvolvimento sócio-econômico do Estado. Para isso, utiliza-se de uma pesquisa exploratória baseada na revisão da literatura existente acerca do tema em comento. Os resultados mostram que o envolvimento de instituições de assistência técnica e científica com os diversos elos do agronegócio café apresenta-se como diferencial estratégico competitivo para a região Amazônica. Também indicam a necessidade da criação e manutenção de associações e cooperativas, da definição de políticas públicas para o setor e da disponibilização de tecnologias adequadas aos produtores para a sustentabilidade da agricultura familiar no Estado e para superar as dificuldades de comercialização.---------------------------------------------------------- --This paper analyzes the coffee agriindustry system in Rondônia as an important segment that generates employment and income, wealth and foreign currency for the State and for the various sectors of economic activity, and which contributes effectively to the socio-economic local development. It examines the main features related since the effective participation of technical and scientific institutions assistance in guiding and supporting the development of the coffee sector until the approach of some alternatives to its culture and management that represent opportunities in coffee agribusiness, with the objective to analyze and highlight its importance for the socio-economic development of the state. For that, it is used an exploratory research based on review of the existing literature on the subject. The results show that the involvement of technical and scientific institutions assistance to the various link of coffee agribusiness it is presented as strategic competitive differential for the Amazon region. Also indicates the need for the creation and maintenance of associations and cooperatives, the definition of public policies for the sector and the provision of appropriate technologies to producers for the sustainability of family farming in the state and to overcome the trading difficulties.Agronegócio, Café, Assistência Técnica, Comercialização, Rondônia, Agribusiness, Coffee, Service, Trading, Rondônia, Agribusiness, Crop Production/Industries,

EFETIVIDADE DOS SISTEMAS DE INFORMAÇÃO DAS AGROINDÚSTRIAS TORREFADORAS E BENEFICIADORAS DE CAFÉ LOCALIZADAS EM PORTO VELHO – RO

A presente pesquisa teve como objetivo avaliar a efetividade dos sistemas de informação disponíveis nas agroindústrias torrefadoras e beneficiadoras de café em Porto Velho – RO. Para tanto, sistematizou-se um referencial teórico acerca dos avanços tecnológicos da sociedade da informação, particularizando alguns conceitos de sistemas de informação e reflexões teóricas sobre a avaliação dos mesmos. É um estudo descritivo, utilizando-se de técnicas de entrevistas e aplicação de formulários com perguntas semi-estruturadas e a observação sistemática in loco. A análise dos dados observados revelou que os sistemas de informação existentes estão facilitando e contribuindo na realização dos trabalhos pelos usuários, fornecendo as informações que precisam, bem como atendendo as atuais necessidades de informação dos gerentes ou tomadores de decisão das agroindústrias de café pesquisadas.--------------------------------------------------This study aimed to evaluate the information systems effectiveness available in coffee agricultural industries torrefadoras and beneficiadoras in Porto Velho - RO. Thus, it was codified a theoretical referential about the technological advances of the information society, specifying some concepts of information systems and theoretical reflections on the evaluation of them. It is a descriptive study, using of interviews techniques and forms application with semi-structured questions and systematic observation spot. The analysis of observed data revealed that existing information systems are facilitating and contributing on the work realization for users, providing the information needed, as well as supplying the current needs of managers information or decision-makers of coffee agriindustries surveyed.Sistemas de Informação, Efetividade de Sistemas de Informação, Agroindústrias de Café, Information Systems, Information Systems Effectiveness, Coffee Agriindustries, Agribusiness,

Luffa operculata effects on the epithelium of frog palate: histological features

SummaryLuffa operculata is the botanical name of buchinha-do-norte or cabacinha, which is a medicinal plant widely used for the treatment of rhinitis and rhinosinusitis. In Europe and USA, it is available in homeopathic medicines. In Brazil, Luffa operculata dry fruit infusion is inhaled or instilled into the nose releasing profuse mucous secretion, thus relieving nasal symptoms. Nevertheless, this often may cause irritation, epistaxis or anosmia.Study designExperimental.Material and MethodThe effects of Luffa operculata were evaluated in different concentration infusions, in isolated frog palate preparation, testing 46 palates after immersion. Four groups (n = 10) were tested with the infusion prepared with frog Ringer (isotonic): control; 60 mg/L; 600 mg/L; and 1200 mg/L. An additional group was tested using the infusion with water (600 mg/L H2O, n = 6). Epithelial samples were harvested to be studied under light microscopy and electron transmission microscopy.ResultsIn treated palates, light microscopy findings were dose-dependent standard toxic changes. Electron transmission microscopy showed enlargement of intercellular spaces and tight junctions disruption, pointing to ion-fluid transport abnormalities. Conclusions: Luffa operculata infusion in currently used doses can promote significant structural and ultrastructural changes in the epithelium of this ex vivo model of respiratory mucosa

Novos genótipos de trigo tolerantes a toxicidade de alumínio obtidos por meio de indução de mutação

Seed from the sensitive wheat (Triticum aestivum L.) cultivar Anahuac was treated to gamma-ray irradiation and eleven Al3+ tolerant mutants selected. The objective was to compare these mutants to the original Anahuac and to the tolerant wheat cultivars IAC-24 and IAC-60 from 1994 to 1996 in acid (Capão Bonito) and limed (Monte Alegre do Sul) soil field trials, in the State of São Paulo, Brazil. Grain yield and agronomic characteristics were analyzed. All the mutant lines yielded higher than the sensitive Anahuac cultivar in the acid soils of Capão Bonito. Under limed soil conditions, 10 mutants had a similar yield to the original sensitive cultivar and one a lower yield. The majority of the mutants were similar in yield to the tolerant cultivars IAC-24 and IAC-60 under both conditions. Some of the mutants showed altered agronomic characteristics, but these alterations did not generally influence the grain yield. The results indicated that tolerant lines with good characteristics may be obtained from a susceptible cultivar by mutation induction, thus allowing cropping under conditions where Al3+ is a limiting factor.Onze mutantes tolerantes a Al3+ foram selecionados a partir de sementes da cultivar de trigo (Triticum aestivum L.) sensível Anahuac, tratadas com raios-gama. O objetivo deste trabalho foi comparar esses mutantes com a cultivar original e as tolerantes IAC-24 e IAC-60 de 1994 a 1996, em ensaios de campo em solo ácido (Capão Bonito) e corrigido (Monte Alegre do Sul) no Estado de São Paulo. Produção de grãos e várias características agronômicas foram analisadas. Todas as linhagens mutantes produziram mais que a cultivar sensível em solos ácidos em Capão Bonito. Em solos corrigidos, dez mutantes apresentaram produção similar à Anahuac original e um, menor produção. A maioria dos mutantes apresentou produção similar à das cultivares tolerantes IAC-24 e IAC-60 em ambas as condições. Alguns dos mutantes mostraram alterações em características agronômicas, mas tais alterações em geral não afetaram a produção de grãos. Os resultados indicaram que linhagens tolerantes com boas características podem ser obtidas de cultivares sensíveis a partir de indução de mutação, permitindo o cultivo em condições nas quais o Al3+ é um fator limitante

New wheat genotypes tolerant to aluminum toxicity obtained by mutation induction

Seed from the sensitive wheat (Triticum aestivum L.) cultivar Anahuac was treated to gamma-ray irradiation and eleven Al3+ tolerant mutants selected. The objective was to compare these mutants to the original Anahuac and to the tolerant wheat cultivars IAC-24 and IAC-60 from 1994 to 1996 in acid (Capão Bonito) and limed (Monte Alegre do Sul) soil field trials, in the State of São Paulo, Brazil. Grain yield and agronomic characteristics were analyzed. All the mutant lines yielded higher than the sensitive Anahuac cultivar in the acid soils of Capão Bonito. Under limed soil conditions, 10 mutants had a similar yield to the original sensitive cultivar and one a lower yield. The majority of the mutants were similar in yield to the tolerant cultivars IAC-24 and IAC-60 under both conditions. Some of the mutants showed altered agronomic characteristics, but these alterations did not generally influence the grain yield. The results indicated that tolerant lines with good characteristics may be obtained from a susceptible cultivar by mutation induction, thus allowing cropping under conditions where Al3+ is a limiting factor.Onze mutantes tolerantes a Al3+ foram selecionados a partir de sementes da cultivar de trigo (Triticum aestivum L.) sensível Anahuac, tratadas com raios-gama. O objetivo deste trabalho foi comparar esses mutantes com a cultivar original e as tolerantes IAC-24 e IAC-60 de 1994 a 1996, em ensaios de campo em solo ácido (Capão Bonito) e corrigido (Monte Alegre do Sul) no Estado de São Paulo. Produção de grãos e várias características agronômicas foram analisadas. Todas as linhagens mutantes produziram mais que a cultivar sensível em solos ácidos em Capão Bonito. Em solos corrigidos, dez mutantes apresentaram produção similar à Anahuac original e um, menor produção. A maioria dos mutantes apresentou produção similar à das cultivares tolerantes IAC-24 e IAC-60 em ambas as condições. Alguns dos mutantes mostraram alterações em características agronômicas, mas tais alterações em geral não afetaram a produção de grãos. Os resultados indicaram que linhagens tolerantes com boas características podem ser obtidas de cultivares sensíveis a partir de indução de mutação, permitindo o cultivo em condições nas quais o Al3+ é um fator limitante

Multifractal characterization as a function of timescale in the light curves with planetary signal observed by the Kepler mission: Caracterização multifractal como uma função da escala de tempo em curvas de luz com sinal planetário observada pela missão Kepler

We investigate the evolution of five multifractal indicators of the Kepler Mission light curves of the moderately young Sun-like Kepler-30 star accompanied by a three-planet system. We focus not only on the fact that the rotational modulation has multifractality properties but also on some studies on these properties based on scale. Then, we systematically investigate the dynamic behaviors of the small and large fluctuations in two types of light curves (PDC and SAP). Those fluctuations indicate that the properties of stellar noise and rotation modulation are highlighted when we apply the Multifractal Detrended Moving Average (MFDMA) algorithm. Our results also demonstrated that the multifractality of the light curve is due to both long-range correlation and broad probability density function, but the main source of multifractality is the long-range correlation. This new approach can be used to develop theoretical and computational models for various stellar magnetic activity-related phenomena and their interactions with the planets, and it can greatly simplify spot modeling from current TESS and future PLATO data

Evaluation of mass attenuation coefficient of concrete sample for different traits

Concrete is widely used in the world and is the main material for civil construction. Due to its properties, it has different uses such as structural, filling and shielding. The aim of this work is to compare experimental and theoretical mass attenuation coefficient for concrete with different traits and determine the one with the best performance. For this, density, X-ray diffraction, mass attenuation coefficient (experimental with a Cs137 source, simulated by MCNP and theoretical determined with XCOM platform) and compressive strength were determined for three different traits of cement mortar (standardized sand, conventional sand and artificial sand). The X-ray diffraction showed more compounds for artificial sand’s samples. Density showed no significant variation. The samples showed a good agreement for experimental, simulated and theoretical mass attenuation coefficient. Standardized sand’s samples had the best performance for mechanical test, with a compressive strength 47.4% higher than artificial sand’s samples and 38.2% higher than conventional sand’s samples. It is possible to conclude that, since mass attenuation coefficient showed no significant difference, standardized sand’s samples is more indicated to be used for shielding than the others

Recurrent respiratory papillomatosis: clinical characteristics and viral genotyping in a Brazilian population

This study presents 25 cases of recurrent respiratory papillomatosis (RRP) that occurred in Sao Luis, Maranhao State, Northeast region, Brazil, between January 2007 and December 2018. Sociodemographic and clinical profile of patients as well as human papillomavirus (HPV) infection status were evaluated. Clinical and histopathological data were collected from the patients’ medical records. For the HPV infection analysis, DNA was extracted and subjected to amplification by a nested polymerase chain reaction. Viral genotyping was performed by automated sequencing. The median age of patients was 12.40 ± 12.6. years, and the juvenile form of the disease (68%) was the predominant form of disease. Female participants were predominant (60%), and they were from cities located in the interior of the State (60%). The most common clinical manifestation was dysphonia; recurrence was observed in most cases (56%), and tracheostomy was necessary in seven patients (26.9%). When comparing the RRP forms, patients in the juvenile-RRP group had higher recurrence rates and need of tracheostomy than those in the adult-RRP group. The viral genotyping analysis revealed that 47.8% of patients had low-risk HPVs, whereas 13.1% had high-risk HPVs, and in 39.1% of patients the viral genotype was not obtained. HPV-6 was the most prevalent type and Juvenile-RRP was more prevalent in our population. HPV was present at a high rate, and HPV-6 was the predominant genotype. This study serves as the basis for further studies to be conducted in the Brazilian population. Our findings aid the better understanding of RRP, possibly suggesting some prognostic factors associated with the disease aggressiveness