3,068 research outputs found

    Processo de decis?o de compra de consumidores de uma loja de lingerie

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    22 f.: il.A lingerie, nos ?ltimos anos, vem tendo uma procura crescente pelo p?blico feminino, onde se tornou pe?a essencial para as mulheres que procuram conforto, delicadeza e sofistica??o. Nesse sentido, este trabalho teve como objetivo principal analisar os fatores que influenciam o processo de decis?o de compra de consumidores de uma loja de lingerie na cidade de Guarabira-PB. O referencial te?rico aborda quest?es relacionadas ao comportamento do consumidor, ao processo de decis?o de compra e a fatores que influenciam o comportamento de compra dos consumidores. Trata-se de uma pesquisa de natureza descritiva e explorat?ria com abordagem quantitativa. A amostra desse estudo foi n?o probabil?stica por conveni?ncia resultando em 176 respondentes. Os resultados obtidos apontam que a maioria dos consumidores da loja investigada desempenham o processo de decis?o de compra, pelo fator pre?o e qualidade do produto. Isso significa que a empresa consegue agregar esses fatores que ? muito importante para os clientes, procurando fortalecer sua imagem no mercado onde atua

    Risco de cr?dito e comportamento financeiro de potenciais empreendedores: uma aplica??o com potenciais clientes de Programas de Empreendedorismo

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    Diante de um ambiente mercadol?gico com alta competitividade, os gestores necessitam cada vez mais tomar decis?es de modo ?gil, no entanto, essa tomada de decis?o deve se dar de modo consciente e embasando para que n?o haja comprometimento do futuro da empresa. Deste modo, ? essencial que o gestor desenvolva pr?ticas cotidianas que envolvam uma gest?o de riscos eficaz, j? que quanto mais mapeados e analisados, menor ser? o risco de executar determinada atividade. Sendo assim, a presen?a do gerenciamento de riscos apresenta-se como uma das principais ferramentas estrat?gicas de uma empresa, principalmente em institui??es financeiras, que trabalham constantemente com conceitos de risco de cr?dito, esses que envolvem a possibilidade de a institui??o financeira n?o receber o valor de um empr?stimo, podendo ser considerado como a taxa de inadimpl?ncia esperada.Em virtude deste cen?rio, este Trabalho de Conclus?o de Curso, de cunho quantitativo, tem como objetivo a identifica??o das vari?veis podem explicar a rela??o entre o comportamento financeiro de potenciais benefici?rios do Empreender Para?ba e o seu risco de cr?dito. Para coleta de dados optou-se pela aplica??o de question?rio, formulado por 24 perguntas, aplicadas indiretamente por meio da ferramenta do Google Docs. A tabula??o de dados foi realizada atrav?s do software Microsoft Office Excel 2007. A an?lise de dados, por sua vez, foi feita atrav?s do software SPSS. Participaram da pesquisa124 potenciais empreendedores. No entanto, ? interessante destacar que a amostra obtida n?o se relaciona a base de dados da Secretaria Executiva do Empreendedorismo ? respons?vel por operacionalizar o Programa Empreender Para?ba, sendo considerada, portanto uma amostra potencial benefici?ria, tendo em vista que todo empreendimento necessita de um investimento monet?rio inicial. Sendo assim, os resultados obtidos na pesquisa est?o restritos a amostra utilizada, n?o cabendo generaliza??es. Os resultados obtidos evidenciam que vari?veis como maior quantidade de filhos, maior n?mero de dependentes financeiros, maior investimento inicial e maior quantidade restante de parcelas de financiamento de ve?culos ou de empr?stimos banc?rios influenciam positivamente a situa??o de inadimpl?ncia. Palavras-chave: Comportamento financeiro, Gerenciamento de riscos

    Dopamine-induced ascorbate release from retinal neurons involves glutamate release, activation of AMPA/Kainate receptors and downstream signaling pathways

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    Ascorbate, the reduced form of Vitamin C, is one of the most abundant and important low-molecular weight antioxidants in living tissues. Most animals synthesize Vitamin C, but some primates, including humans, have lost this capacity due to disruption in L-gulono-gamma-lactone oxidase gene. Because of this incapacity, those animals must obtain Vitamin C from the diet. Ascorbate is highly concentrated in the central nervous system (CNS), including the retina, and plays essential roles in neuronal physiology. Ascorbate transport into cells is controlled by Sodium Vitamin C Co-Transporters (SVCTs). There are four SVCT isoforms and SVCT2 is the major isoform controlling ascorbate transport in the CNS. Regarding ascorbate release from retinal neurons, Glutamate, by activating its ionotropic receptors leads to ascorbate release via the reversion of SVCT2. Moreover, dopamine, via activation of D1 receptor/cyclic AMP/EPAC2 pathway, also induces ascorbate release via SVCT2 reversion. Because the dopaminergic and glutamatergic systems are interconnected in the CNS, we hypothesized that dopamine could regulate ascorbate release indirectly, via the glutamatergic system. Here we reveal that dopamine increases the release of D-Aspartate from retinal neurons in a way independent on calcium ions and dependent on excitatory amino acid transporters. In addition, dopamine-dependent SVCT2 reversion leading to ascorbate release occurs by activation of AMPA/Kainate receptors and downstream ERK/AKT pathways. Overall, our data reveal a dopamine-to-glutamate signaling that regulates the bioavailability of ascorbate in neuronal cells.This work was supported by grants from Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), and Pró-Reitoria de Pesquisa, Pós-Graduação e Inovação da Universidade Federal Fluminense (PROPPI/UFF). TGE, ID, and NAO were recipients of graduate student fellowships from CAPES. RPC is a research fellow from CNPq and FAPERJ. CCP and RS hold employment contracts financed by national funds through FCT – Fundação para a Ciência e a Tecnologia, I.P., in the context of the program-contract described in paragraphs 4, 5 and 6 of art. 23 of Law no. 57/2016, of August 29, as amended by Law no. 57/2017 of July 19

    EVALUATION OF THE CHEMICAL COMPOSITION AND ALLELOPATHIC POTENTIAL OF ESSENTIAL OILS FROM THREE SPECIES OF ASTERECEAE AGAINST SEED GERMINATION AND SEEDLING VIGOR OF LETTUCE

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    The allelopathic properties of the essential oils have been exploited because they are biodegradable natural compounds that can be used in combination or as prototypes for new bioherbicides. The objectives of this study were to chemically characterize the essential oils from B. dracunculifolia, C. bonariesis and T. diversifolia and to evaluate their allelopathic potential. The essential oils were extracted by hydrodistillation and their chemical compositions were determined by GC-MS. Allelopathic activities were determined by methods that evaluate the effects of volatile compounds and direct contact of those compounds on the seed germination and seedling vigor of lettuce. The principal constituents of the essential oil from B. dracunculifolia were limonene, trans-nerolidol and β-pinene; those in the oil from C. bonariesis were limonene, trans-β-ocimene and cis-verbenol (4.4%); and those in the oil from T. diversifolia were β-pinene, α-pinene and limonene. Minor differences in the germination and vigor of lettuce seedlings were observed when they were exposed to the volatile essential oils from the leaves of the three species of the Asteraceae family. However, upon direct contact with these oils, those of C. bonariesis presented the greatest allelopathic potential, which was attributed to its higher content of oxygenated monoterpenes

    The molecular detection of different Leishmania species within sand flies from a cutaneous and visceral leishmaniasis sympatric area in Southeastern Brazil

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    Over the last 20 years, there has been an increase in the number of leishmaniasis cases in Brazil. Belo Horizonte (BH) is one of the most highly populated Brazilian cities that is affected by visceral leishmaniasis (VL). The health services in BH are coordinated by a central nucleus that is subdivided into nine sanitary districts. Historically, the highest level of human VL cases was found in the northeast sanitary district (NSD). The objective of our study was to detect Leishmania infection in the phlebotomine sand flies collected in the NSD by dissection and molecular approaches. Following the occurrence of human VL cases in 2005, entomological captures were performed from July 2006-June 2007. Out of the 245 sand flies dissected, only three Lutzomyia longipalpis spp contained flagellates. The female sand flies were grouped into 120 pools according to date, collection site and species, with approximately 10 individual sand flies in each pool. Subsquently, the DNA was extracted and Leishmania spp and other parasites were detected and identified by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorfism. Leishmania infantum was present in at least 19% of the Lu. longipalpis collected, in 3.8% of the Nyssomiya whitmani collected, in 33.3% of the Evandromiya termitophila collected and in 14.3% of the Nyssomiya intermedia collected. When the females of the cortelezzii complex were compared with each other, 3.2% of the females were infected with Leishmania braziliensis, whereas 3.2% of the females were infected with trypanosomatids
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