Sustainability in Growth Models

We study the relation between sustainability and national income in a neoclassical growth model with one product, which is used both as consumption good and investment good, and one natural resource, which is used in production. We analyse the possibilities for an indicator of sustainability, looking in particular at two indicators: the change in real national wealth and the ratio between sustainable constant consumption and actual consumption. It appears that both indicators can only be computed if the sustainable path of the economy is first computed, ànd that they must be computed for the whole future path of the economy, so that it is not sufficient to compute them for a single time period. For official statistics this means that sustainability indicators can only be computed by means of an economic model, and cannot be measured with actual data only

Sustainability in Growth Models

We study the relation between sustainability and national income in a neoclassical growth model with one product, which is used both as consumption good and investment good, and one natural resource, which is used in production. We analyse the possibilities for an indicator of sustainability, looking in particular at two indicators: the change in real national wealth and the ratio between sustainable constant consumption and actual consumption. It appears that both indicators can only be computed if the sustainable path of the economy is first computed, ànd that they must be computed for the whole future path of the economy, so that it is not sufficient to compute them for a single time period. For official statistics this means that sustainability indicators can only be computed by means of an economic model, and cannot be measured with actual data only

Acute flaccid myelitis and Guillain-Barre syndrome in children:A comparative study with evaluation of diagnostic criteria

BACKGROUND AND PURPOSE: Differentiation between acute flaccid myelitis (AFM) and Guillain–Barré syndrome (GBS) can be difficult, particularly in children. Our objective was to improve the diagnostic accuracy by giving recommendations based on a comparison of clinical features and diagnostic criteria in children with AFM or GBS. METHODS: A cohort of 26 children with AFM associated with enterovirus D68 was compared to a cohort of 156 children with GBS. The specificity of the Brighton criteria, used for GBS diagnosis, was evaluated in the AFM cohort and the specificity of the Centers for Disease Control and Prevention (CDC) AFM diagnostic criteria in the GBS cohort. RESULTS: Children with AFM compared to those with GBS had a shorter interval between onset of weakness and nadir (3 vs. 8 days, p < 0.001), more often had asymmetric limb weakness (58% vs. 0%, p < 0.001), and less frequently had sensory deficits (0% vs. 40%, p < 0.001). In AFM, cerebrospinal fluid leukocyte counts were higher, whereas protein concentrations were lower. Spinal cord lesions on magnetic resonance imaging were only found in AFM patients. No GBS case fulfilled CDC criteria for definite AFM. Of the AFM cases, 8% fulfilled the Brighton criteria for GBS, when omitting the criterion of excluding an alternate diagnosis. CONCLUSIONS: Despite the overlap in clinical presentation, we found distinctive early clinical and diagnostic characteristics for differentiating AFM from GBS in children. Diagnostic criteria for AFM and GBS usually perform well, but some AFM cases may fulfill clinical diagnostic criteria for GBS. This underlines the need to perform diagnostic tests early to exclude AFM in children suspected of atypical GBS

Continuous athlete monitoring in challenging cycling environments using IoT technologiesis

Internet of Things (IoT)-based solutions for sport analytics aim to improve performance, coaching, and strategic insights. These factors are especially relevant in cycling, where real-time data should be available anytime, anywhere, even in remote areas where there are no infrastructure-based communication technologies (e.g., LTE and Wi-Fi). In this article, we present an experience report on the use of state-of-the-art IoT technologies in cycling, where a group of cyclists can form a reliable and energy efficient mesh network to collect and process sensor data in real-time, such as heart rate, speed, and location. This data is analyzed in real-time to estimate the performance of each rider and derive instantaneous feedback. Our solution is the first to combine a local body area network to gather the sensor data from the cyclist and a 6TiSCH network to form a multihop long-range wireless sensor network in order to provide each bicycle with connectivity to the sink (e.g., a moving car following the cyclists). In this article, we present a detailed technical description of this solution, describing its requirements, options, and technical challenges. In order to assess such a deployment, we present a large publicly available data-set from different real-world cycling scenarios (mountain road cycle racing and cyclo-cross) which characterizes the performance of the approach, demonstrating its feasibility and evidencing its relevance and promising possibilities in a cycling context for providing low-power communication with reliable performance

On hyperovals of polar spaces

We derive lower and upper bounds for the size of a hyperoval of a finite polar space of rank 3. We give a computer-free proof for the uniqueness, up to isomorphism, of the hyperoval of size 126 of H(5, 4) and prove that the near hexagon E-3 has up to isomorphism a unique full embedding into the dual polar space DH(5, 4)

Car Driving Performance in Hemianopia:An On-Road Driving Study

PURPOSE. To study driving performance in people with homonymous hemianopia (HH) assessed in the official on-road test of practical fitness to drive by the Dutch driver's licensing authority (CBR).METHODS. Data were collected from a cohort (January 2010-July 2012) of all people with HH following the official relicensure trajectory at Royal Dutch Visio and the CBR in the Netherlands. Driving performance during the official on-road tests of practical fitness to drive was scored by professional experts on practical fitness to drive, using the visual impairments protocol and a standardized scoring of visual, tactical and operational aspects. Age ranged from 27 to 72 years (mean = 52, SD = 11.7) and time since onset of the visual field defect ranged from 6 to 41 months (mean = 15, SD = 7.5).RESULTS. Fourteen (54%) participants were judged as fit to drive. Besides poor visual scanning during driving, specific tactical, and operational weaknesses were observed in people with HH that were evaluated as unfit to drive. Results suggest that judgement on practical fitness to drive cannot be based on solely the visual field size. Visual scanning and operational handling of the car were found to be more impaired with longer time not driven, while such an effect was not found for tactical choices during driving.CONCLUSIONS. Training programs aimed at improving practical fitness to drive in people with HH should focus on improving both visual scanning, as well as driving aspects such as steering stability, speed adaptation, and anticipating environmental changes.</p

Food System Resilience

The COVID-19 crisis is just one in a series of shocks and stressors that exemplify the importance of building resilient food systems. To ensure that desired food system outcomes are less fluctuating, policy makers and other important stakeholders need a common narrative on food system resilience. The purpose of this paper is to work towards a joint understanding of food system resilience and its implications for policy making. The delivery of desired outcomes depends on the ability of food systems to anticipate, prevent, absorb, and adapt to the impacts of shocks and stressors. Based on our literature review we found four properties of food systems that enhance their resilience. We refer to these as the A B C D of resilience building: Agency, Buffering, Connectivity and Diversity. Over time, many food systems have lost levels of agency, buffering capacity, connectivity or diversity. One of the principal causes of this is attributed to the governance of food systems. Governance is inherently political: as a result of conflicting interests and power imbalances, food systems fail to deliver equitable and just access to food. Moreover, the impacts of shocks and stressors are not evenly distributed across actors in the food system. This paper has highlighted the importance of more inclusive governance to direct food system transformation towards such higher levels of resilience. We conclude that we cannot leave this to the market, but that democratic and before all independent, credible institutions are needed to create the necessary transparency between actors as to their interests, power and influence

Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis

Abstract Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) seem to be opposite entities from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases. Emphysema is caused by an elastase/anti-elastase imbalance leading to accelerated elastin degradation. Elastinolysis is however, also accelerated in the IPF patients’ lungs. The amino acids desmosine and isodesmosine (DES) are unique to elastin. During the degradation process, elastases liberate DES from elastin fibers. Blood DES levels consequently reflect the rate of systemic elastinolysis and are increased in COPD. This is the first report describing elevated DES levels in IPF patients. We also demonstrated that the age-related increment of DES concentrations is enhanced in IPF. Our current study suggests that elastinolysis is a shared pathogenic step in both COPD and IPF. Further investigation is required to establish the relevance of accelerated elastin degradation in IPF and to determine whether decelerating this process leads to slower progression of lung fibrosis and better survival for patients with IPF.https://deepblue.lib.umich.edu/bitstream/2027.42/142803/1/12931_2018_Article_747.pd

Acute flaccid myelitis and Guillain-Barré syndrome in children: A comparative study with evaluation of diagnostic criteria

Background and purpose: Differentiation between acute flaccid myelitis (AFM) and Guillain-Barré syndrome (GBS) can be difficult, particularly in children. Our objective was to improve the diagnostic accuracy by giving recommendations based on a comparison of clinical features and diagnostic criteria in children with AFM or GBS. Methods: A cohort of 26 children with AFM associated with enterovirus D68 was compared to a cohort of 156 children with GBS. The specificity of the Brighton criteria, used for GBS diagnosis, was evaluated in the AFM cohort and the specificity of the Centers for Disease Control and Prevention (CDC) AFM diagnostic criteria in the GBS cohort. Results: Children with AFM compared to those with GBS had a shorter interval between onset of weakness and nadir (3 vs. 8 days, p < 0.001), more often had asymmetric limb weakness (58% vs. 0%, p < 0.001), and less frequently had sensory deficits (0% vs. 40%, p < 0.001). In AFM, cerebrospinal fluid leukocyte counts were higher, whereas protein concentrations were lower. Spinal cord lesions on magnetic resonance imaging were only found in AFM patients. No GBS case fulfilled CDC criteria for definite AFM. Of the AFM cases, 8% fulfilled the Brighton criteria for GBS, when omitting the criterion of excluding an alternate diagnosis. Conclusions: Despite the overlap in clinical presentation, we found distinctive early clinical and diagnostic characteristics for differentiating AFM from GBS in children. Diagnostic criteria for AFM and GBS usually perform well, but some AFM cases may fulfill clinical diagnostic criteria for GBS. This underlines the need to perform diagnostic tests early to exclude AFM in children suspected of atypical GBS.The Prinses Beatrix Spierfonds funded the PhD project of J.R. on GBS in children (project number: W.OR12-04)S