Chitosan film for treatment of cutaneous wound in a female cat

Chitosan and alginate have the capacity to absorb the secretion, to stimulate collagen production and to restore tissue lesions, and were proved to be biocompatible and biodegradable. This article describes the treatment of an open infected bite-injury located on the right side of the abdominal-chest region, with subcutaneous-tissue loss, in a cat. Chitosan and chitosan-alginate films developed in the Department of Biotechnological Process of the Chemical Engineering School of the State University of Campinas (Unicamp) were used to cover the wound. These film dressings were changed at intervals of 48, 72 hours, and at 4, 7, 14, 21, and 24 days. On the 30th day the patient was released. Facing the satisfactory evolution of the injury, one may conclude that both films were effective for the treatment of the described case, leading to a healthy granulation reconstruction of the tissue, and to quick healing and scaring within 30 days

Hérnia perineal associada à colagenopatia em uma cadela

A hérnia perineal acomete mais freqüentemente cães machos de meia idade e idosos, não castrados, podendo ser uni ou bilateral. A apresentação desta doença na fêmea pode ser sugestiva de alguma alteração estrutural no colágeno que leva às alterações da matriz extracelular. Sendo assim, o objetivo deste trabalho foi descrever um caso de hérnia perineal associada à colagenopatia em uma cadela. Foi examinada uma cadela Pinscher de 3 anos de idade, portadora de hérnia perineal bilateral. Foi observado hiperextensibilidade da pele. Este animal foi submetido á reparação da hérnia onde havia laceração da pele durante a dermorrafia. Foi realizada biópsia e coloração com HE e as alterações observadas foram diminuição do número de fibras colágenas na derme, que apresentavam aparente desordem na sua estrutura, notando-se raros feixes de fibras com acentuada fragmentação. Foi possível concluir que os achados clínicos e alterações histopatológicas são compatíveis com astenia cutânea na cadela

Morphological Aspects of the Superficial Lymph Nodes of Myrmecophaga tridactyla

Background: The giant anteater is a Xenarthra of the Myrmecophagidae family. It is classified in Brazil as vulnerable specie, however, in Rio de Janeiro and Rio Grande do Sul it is probably extinct. In an attempt to contribute to the preservation of the species, many injured animals are referred for treatment and rehabilitation, but the lack of information about morphology may hinder a more efficient clinical-surgical approach. The knowledge on the topography, dimensions and morphology of lymph nodes of a given species is essential for medical practice. The aim of this study was to identify and describe the general morphology of the superficial lymph nodes of Myrmecophaga tridactyla.Materials, Methods & Results: Ten cadavers of adult Myrmecophaga tridactyla were used in this study. They were fixed and preserved with 10% formaldehyde solution and dissected throughout their length to locate their superficial lymph nodes. Lymph nodes of each center were removed for mesoscopic analysis. Measurements of width, length and thickness were obtained by a digital caliper. The superficial lymph nodes observed in the head were the mandibular and the intermandibular, while in the neck were identified superficial cervical and deep cervical lymph nodes. In the thoracic limbs, the axillary and the axillary accessory lymph nodes were present. In the pelvic limbs just one lymph node, the femoral, was observed, located in the thick subcutaneous fascia of the medial surface of the thigh. The main anatomical differences found in the lymph nodes of M. tridactyla are the absence of parotid, popliteal and subiliac lymph nodes and the presence of intermandibular lymph nodes and the developed femoral lymph nodes, which are unique in the pelvic limbs of this species. Moreover, some superficial lymph nodes were formed by several small lymph nodes, forming clusters, as observed in the proper and accessory axillary and femoral lymph nodes.Discussion: The lymph nodes of the head, neck and forelimbs of the M. tridactyla followed the pattern observed in domestic animals and rats, while the morphological pattern of the lymph nodes of the head and the hindlimb differed from that described in domestic animals. Different from the dogs and ruminants where a range of superficial lymph nodes can be normally palpated, such as the mandibular; retropharyngeal; superficial cervical; subiliac; popliteal; mammary and superficial inguinal, only the femoral lymph nodes are palpable in M. tridactyla. The main reasons for this are the greater thickness of the skin and the absence of certain classic lymphocytes in the anteater. The peculiar anatomical features of the head and neck of M. tridactyla may have induced changes in the lymph centers of these regions when compared to the morphologic pattern of the terrestrial mammals in general. The lymph drainage of the neck, forelimbs and trunk wall was considered to be similar to that of dog, since there is equivalence of lymph nodes between these two species. The lymphatic afferents of the abdominal wall, gluteal region and hindlimbs are probably directed to the large femoral lymph nodes, which differs from domestic animals, whose lymph are mainly drained to the subiliac, ischiatic and popliteal lymph nodes. The anatomical differences related to the number, size and topography of the lymph nodes observed in M. tridactyla may be relevant in the medical procedures of this species

Análise histomorfológica dos linfonodos superficiais do tamanduá-mirim (tamandua tetradactyla, linnaeus, 1758) / Histomorphological analysis of tamanduá-mira surface lymphods (tamandua tetradactyla, linnaeus, 1758)

O Tamandua tetradactyla, conhecido como tamanduá-mirim, frequentemente necessita de assistência médico veterinária devido ao alto índice de atropelamentos, caça, queimadas e ataque de predadores. A carência de estudos e conhecimento em relação as peculiaridades morfoanatômicas e fisiológicas da espécie limita a prática clínica da espécie. O estudo histomorfológico aplicado aos linfonodos permite complementar a análise morfológica e obter maior conhecimento acerca da anatomia e fisiologia dos mesmos. Sendo assim, foi realizada a análise histomorfológica dos linfonodos superficiais de seis tamanduás-mirins para contagem dos nódulos linfoides, mensuração dos centros germinativos e de proporção entre região medular e região cortical dos linfonodos, além de descrição geral dos aspectos histológicos

Fibrossarcoma de ducto biliar em gato

Fibrossarcoma felino é uma neoplasia maligna, localmente invasiva e de tecido conjuntivo fibroso que, em alguns gatos, está associada à vacinação, particularmente a vacinas com adjuvantes. Ocasionalmente, fibrossarcoma aparece naturalmente, não associado à vacina. O presente artigo relata o caso de um felino macho de 10 anos de idade, com um histórico de emagrecimento crônico há alguns meses e aumento do volume abdominal cranial. Através de exames ultrassonográfico e radiográfico, identificou-se uma massa na região hipogástrica e diante do quadro, encaminhou-se o animal à laparotomia exploratória. A neoplasia localizava-se na região do ducto biliar e uma segunda massa solitária foi identificada no lobo caudado do fígado. Houve a remoção cirúrgica dos tumores e a coleta de amostras para exame histopatológico. De acordo com os achados dos exames por imagem, avaliação macroscópica e histopatológica, o diagnóstico foi fibrossarcoma primário de ducto biliar

SYSTEM WITH BARRIER FILM hydrogel poly (2-hydroxyethyl METHACRYLATE) IN PREVENTION OF peritoneal adhesions: EXPERIMENTAL STUDY IN RATS AND bitches

Made available in DSpace on 2014-07-29T15:13:55Z (GMT). No. of bitstreams: 1 Marcelo Seixo - digitalizados tese.pdf: 3279535 bytes, checksum: 24af83caa54ca7c77d0f55b99fbb329f (MD5) Previous issue date: 2009-01-16Synthetic materials are the leading choice for the correction of defects in abdominal wall, but the formation of adhesions are a problem encountered when placing implants in contact with the abdominal viscera. With In order to avoid its formation, various materials and mechanisms are used in an attempt to prevent contact with peritoneal surfaces of the prostheses. In this sense, we investigated the possibility of the hydrogel poly (2-hydroxyethyl methacrylate) (polyHEMA) coating a face of polypropylene mesh and thereby preventing peritoneal adhesion in dogs and rats, and, in the latter species, also performed a histological evaluation of implanted materials. For this, an abdominal defect was created in the rectus abdominis of 16 bitches were divided into two groups of eight animals and the defect was corrected with screen polypropylene and polypropylene mesh coated with hydrogel, respectively. The presence of adhesions was evaluated after 20 days by laparoscopy. As to rats, the surgical procedure was similar and the evaluations were performed at 15 and 30 days, with euthanasia and collection of fragments for histology with picrosirius red staining and HE The hydrogel coating the polyHEMA polypropylene mesh implanted in the abdominal wall prevented completely visceral adhesions and omentum remaining on the surface the screen when compared to polypropylene mesh in dogs and isolated rats. Was found greater amount of adhesions in the suture zone in the group a mesh coated with polyHEMA. The physical structure of the biomaterial interfered the organization and persistence of tissue response, but not in the same type.Os materiais sintéticos são a principal escolha para a correção de defeitos na parede abdominal, mas a formação de aderências é um problema encontrado quando da colocação de próteses em contato com as vísceras abdominais. Com o objetivo de evitar a sua formação, vários materiais e mecanismos são utilizados na tentativa de impedir o contato das superfícies peritoniais com as próteses. Neste sentido, investigou-se a possibilidade do hidrogel de poli(2-hidroxietil metacrilato) (poliHEMA) revestir uma face de tela de polipropileno e, com isso, prevenir a aderência peritonial em cadelas e ratas, sendo, nesta última espécie, também realizada a avaliação histológica dos materiais implantados. Para isso, um defeito abdominal foi produzido no músculo reto abdominal de 16 cadelas que foram divididas em dois grupos de oito animais e, o defeito foi corrigido com tela de polipropileno e tela de polipropileno revestida de hidrogel respectivamente. A presença de aderências foi avaliada após 20 dias por videolaparoscopia. Quanto às ratas, o procedimento cirúrgico foi semelhante e as avaliações ocorreram aos 15 e 30 dias, com eutanásia dos animais e colheita de fragmentos para histologia com as colorações de picrossirius e H.E. O hidrogel de poliHEMA revestindo a tela de polipropileno implantada na parede abdominal impediu totalmente a formação de aderências viscerais e do omento remanescente sobre a superfície da tela quando comparada à tela de polipropileno isolada em cadelas e ratas. Foi encontrada maior quantidade de aderências na zona de sutura no grupo que recebeu a tela revestida com poliHEMA. A estrutura física do biomaterial interferiu na organização e persistência da resposta tissular, mas não no tipo da mesma

Carcinoma escamoso oral em gato jovem

Background:  :  : Oral neoplasms are common in cats. Just the percentage of oral squamous cell carcinoma (SCC) accounts for about 70% of all feline oral tumors also it is considered highly invasive and malignant. There are reports that the flea collar increases five times the risk oral SCC development. In addition, smoke exposure is also considered a risk factor, and the animals were exposed to tobacco when makes it self-cleaning. SCC well differentiated is characterized histologically by numerous keratin pearls formation and clearly evident intercellular bridges with poor mitotic activity and nuclear pleomorphism. The median age of cats with oral SCC is about 11-13 years, but, cats as young as three years and as old as twenty-one years have been previously reported. However, it was not found reports of oral SCC in cats at age younger than one year old. The aim of this article is reports one case of oral SCC feline at age of three months old. Five days after surgical procedure the patient returned to the veterinary and the owner report that it returned to eating well. Case: It was exanimate a three months old male mixed breed cat presenting oral volume increased and the biopsy test was suggested. However, the owner returned 3 months later when the animal showed tumor 6 cm in diameter, dysphagia, tongue protrusion, excessive salivation, halitosis and weight loss. It was indicated a wide surgical excision of tumoral mass. The tissue was submitted to histopathology. Discussion: The historical, macroscopic characteristics and predisponents factors may aid in carcinoma diagnosis, however, the cytologic or histological examination of tissue confirms this diagnosis. Therefore, the microscopic evaluation revealed a malignant neoplastic proliferation of stratified squamous epithelial cells desmosomal junctions evident, few foci keratin pearl formation and presence of mononuclear inflammatory reaction perifocal. A well-differentiated squamous cell carcinoma was diagnosed by histological study. Thirty days after the surgical procedure, the animal showed a complete recovery with weight increase and eating normally. Thus, surgery proves to provide excellent quality of life maintenance for a long period of time and, although it had shown no signs of recurrence at the present moment, the literature describes that SCC long-term recurrences are common. Indeed, an important question is the quality of life of the felines with oral SCC, whereas this neoplasm led to a marked decrease in eating and drinking due to pain. Therefore, the treatment target is making the possible to maintain an excellent quality of life as long as possible. With the surgery was possible the maintenance of an excellent quality of life for a longer period. An early diagnosis could have defined the need for surgical procedure before the animal presented clinical signs characteristic, whereas represent a locally invasive neoplasm with poor response to conventional treatments models and unfavorable prognosis. Actually, increased incidences of SCC have been associated with clinical and preventive veterinary medicine improvements, which led to the prolongation of life to this animal, becoming more susceptible to senile disease, but this paper reports one case of oral SCC feline at age of three months old

Prevalence Level of the caudal cava vein formation in the dog

v.6, n.4, p. 62-72, out./dez. 2009.Submitted by Marlene Santos ([email protected]) on 2013-09-16T19:25:01Z No. of bitstreams: 1 8788-33543-1-PB.pdf: 501280 bytes, checksum: fe0a387760bb1ac5f4445514b86b4f23 (MD5)Approved for entry into archive by Claudia Moura ([email protected]) on 2013-10-23T17:31:42Z (GMT) No. of bitstreams: 1 8788-33543-1-PB.pdf: 501280 bytes, checksum: fe0a387760bb1ac5f4445514b86b4f23 (MD5)Approved for entry into archive by Claudia Moura ([email protected]) on 2013-10-23T17:32:41Z (GMT) No. of bitstreams: 1 8788-33543-1-PB.pdf: 501280 bytes, checksum: fe0a387760bb1ac5f4445514b86b4f23 (MD5)Made available in DSpace on 2013-10-23T17:32:53Z (GMT). No. of bitstreams: 1 8788-33543-1-PB.pdf: 501280 bytes, checksum: fe0a387760bb1ac5f4445514b86b4f23 (MD5) Previous issue date: 2009-12Pró-Reitoria de Pesquisa e Pós-Graduação da Universidade Federal de Goiás.A veia cava caudal no cão é a via de drenagem do sangue, advindo da pelve e membros posteriores. O nível de união das veias ilíacas comuns, direita e esquerda formando a veia cava caudal pode apresenta variação. Este trabalho teve como objetivo, avaliar a prevalência do nível de formação da veia cava caudal do cão. Foram utilizados 104 cães, sem raça definida, de ambos os sexos, fixados em formol, dissecados e analisados macroscopicamente quanto ao nível de formação da veia cava caudal. A veia cava caudal apresentou-se com freqüência de formação de 1,93% ao nível das vértebras lombares L3 e L6 e com prevalência de 95,19% ao nível da sétima vértebra lombar. As veias circunflexas ilíacas profundas, direita e esquerda apresentaram drenagem para a veia cava caudal, ambas cranialmente ao nível de sua formação, em 92,31% dos casos e de 3,85% ao nível desta formação. Estes vasos também se apresentaram com drenagem, ambas para as veias ilíacas comuns (2,89%), ou ainda em 0,96% dos casos com a veia circunflexa ilíaca profunda direita para veia cava caudal, e a veia circunflexa ilíaca profunda esquerda para a veia ilíaca comum esquerda. Em 1,93% ocorreu uma ponte de ligação entre as veias ilíacas comuns, direita e esquerda. Portanto, a formaçãoda veia cava caudal do cão oscila entre L3 e L7, com maior freqüência neste último nível. As veias circunflexas ilíacas profundas drenam cranialmente ou ao nível da formação da veia cava caudal, porém, ainda que em menor freqüência, para uma ou ambas as veias ilíacas comuns. Não houve indícios de que, estas variações no nível de formação da veia cava caudal, determinem prejuízos na drenagem da pelve e membros posteriores de caninos.The caudal cava vein in the dog is the way to drain the blood that comes from the pelvis and the back limbs. The caudal cava vein formed by the level of union of the common iliac veins – left and right, can show variation. The aim of this study is to evaluate the level of prevalence of the caudal cava vein formation of the dog. One hundred and four (104) of none defined breed dogs were researched. They were of both gender and fixed in formalin aqueous solution, also dissected and macroscopically analyzed to the level of the caudal cava vein formation. The caudal cava vein showed the formation frequency of 1,93% to the level of the L3 and L6 lumber vertebras. Also prevailing the 95,19% to the level of the seventh (7th) lumber vertebra. The circumflex deep iliac veins – right and left showed the drain to the caudal cava vein, both cranially to the level of its formation (in 92,31% of the cases), and 3,85% to the level of these formation. These vessels also showed with drain, both to the common iliac veins (2,89%), or in 0,96% of the cases with the right circumflex deep iliac vein to the caudal cava vein, and the left circumflex deep iliac vein to the left common iliac vein. In 1,93%, happened a link between the common iliac veins, right and left. So its formation in the dog vary between L3 and L7 – being more frequent in this last level. The circumflex deep iliac veins drain cranially to the level of the formation of the caudal cava vein. But in less frequency to one or both common iliac veins. The study showed that the variations in the level of formation of the caudal cava vein that didn’t harm the drain of the pelvis and back limb in these anim

2-hydroxyethyl methacrylate composite - polypropylene mesh for preventing peritoneal adhesions in female dogs Compósito 2-hidroxietil dimetacrilato-tela de polipropileno para prevenção de aderências peritoneais em cadelas

PURPOSE: To evaluate whether the lining facing the visceral side of polypropylene mesh made with 2-hydroxyethyl methacrylate (p(HEMA)) hydrogel could avoid peritoneal adhesion in female dogs. METHODS: Eight animals (group PP) had a polypropylene mesh implanted to correct a defect in the rectal abdominal muscle, whereas in the other group (group PH) the polypropylene mesh was coated with p(HEMA) composite on the surface facing the peritoneal area. RESULTS: Adhesions were observed on the mesh in 62.5% of the PP group. In the PH group adhesions were present only on the suture lines. CONCLUSION: p(HEMA) hydrogel was well tolerated and effective in avoiding visceral and omental adhesions on the surface of the polypropylene mesh.<br>OBJETIVO: Avaliar se o revestimento da face visceral de uma tela de polipropileno com 2-hidroxietil dimetacrilato (p(HEMA)) poderia evitar aderências peritoniais em cadelas. MÉTODOS: Em oito animais (Grupo PP) foram implantadas telas de polipropileno para correção de um defeito do músculo reto abdominal, enquanto em outro grupo (Grupo PH) fez-se a implantação de uma tela de polipropileno cuja face peritonial foi revestida por 2-hidroxietil dimetacrilato (p(HEMA)). RESULTADOS: Foram observados 62,5% de aderências peritoniais sobre a tela nos animais do Grupo PP, enquanto que no Grupo PH estas não ocorreram, exceto sobre a linha se sutura. CONCLUSÃO: O hidrogel de p(HEMA) foi bem tolerado pelos animais e mostrou-se efetivo na prevenção das aderências viscerais e omentais sobre a tela de polipropileno