Cosmic-ray measurements by reconstructing longitudinal profiles for the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) will be the next generation gamma-ray observatory in the energy range from 20 GeV to 300 TeV, offering 5-10 times better flux sensitivity than the current generation of imaging atmospheric Cherenkov telescopes. Each telescope will capture an image of the Cherenkov light produced when air showers created by gamma rays or cosmic rays pass through the atmosphere. The longitudinal development of the shower in the atmosphere can be studied by measuring the number of charged particles produced as a function of depth. The reconstruction of the longitudinal shower profile provides the depth of the shower maximum Xmax which is a mass-sensitive parameter useful for cosmic ray composition. In this work, we reconstruct the longitudinal profile and the Xmax of air showers initiated by two kinds of cosmic ray species, proton, and iron, with energies between 10 TeV and 300 TeV. This reconstruction is different from other methods that have been used in the past as template-based fit techniques that require a detailed and computing-intensive simulation chain. In contrast, we use for the first time a parameterized function for the angular distribution of Cherenkov light around the shower axis.</p

Drivers for spatial modelling of a critically endangered seabird on a dynamic ocean area: Balearic shearwaters are non-vegetarian

1. Spatial modelling is an important research tool to improve our knowledge about the distribution of wildlife in the ocean. Using different modelling techniques (MaxEnt and a generalized linear mixed model), a predictive habitat suitability model was developed for one of the most threatened seabirds in the world: the Balearic shearwater, Puffinus mauretanicus. 2. Models were developed using a 10-year dataset from the Gulf of Cádiz (on the south-western Iberian Peninsula), a key foraging area for Balearic shearwaters during migration and the non-breeding season. 3. Predictive habitat maps strongly matched the observed distribution patterns, pointing to bathymetric features as the main modelling drivers. The species was concentrated on shallow areas (up to approximately 100 m in depth) of the continental shelf, very close to the mouth of the Guadalquivir River. In contrast with previous studies, Balearic shearwater distribution in the highly dynamic Gulf of Cádiz was not correlated with areas of high chlorophyll a concentration. 4. This lack of spatial correlation probably arises from the delay between the phytoplankton bloom and the response of the zooplankton and small fish that are preyed upon by Balearic shearwaters, which may result in important displacements of this trophic chain across the Gulf of Cádiz. 5. The analysis presented contributes to a better understanding of the spatial distribution and ecology of the critically endangered top predator in the Gulf of Cádiz and offers important information to improve management plans.Versión del editor1,92

A MegaCam Survey of Outer Halo Satellites. VI: The Spatially Resolved Star Formation History of the Carina Dwarf Spheroidal Galaxy

We present the spatially resolved star formation history (SFH) of the Carina dwarf spheroidal galaxy, obtained from deep, wide-field g,r imaging and a metallicity distribution from the literature. Our photometry covers $\sim2$ deg$^2$, reaching up to $\sim10$ times the half-light radius of Carina with a completeness higher than $50\%$ at $g\sim24.5$, more than one magnitude fainter than the oldest turnoff. This is the first time a combination of depth and coverage of this quality has been used to derive the SFH of Carina, enabling us to trace its different populations with unprecedented accuracy. We find that Carina's SFH consists of two episodes well separated by a star formation temporal gap. These episodes occurred at old ($>10$ Gyr) and intermediate ($2$-$8$ Gyr) ages. Our measurements show that the old episode comprises the majority of the population, accounting for $54\pm5\%$ of the stellar mass within $1.3$ times the King tidal radius, while the total stellar mass derived for Carina is $1.60\pm0.09\times 10^{6} M_{\rm{\odot}}$, and the stellar mass-to-light ratio $1.8\pm0.2$. The SFH derived is consistent with no recent star formation which hints that the observed blue plume is due to blue stragglers. We conclude that the SFH of Carina evolved independently of the tidal field of the Milky Way, since the frequency and duration of its star formation events do not correlate with its orbital parameters. This result is supported by the age/metallicity relation observed in Carina, and the gradients calculated indicating that outer regions are older and more metal poor.Comment: Accepted in ApJ (22 pages, 13 figures

Methodology proposal for the location of microsatellites in the equine genome

We present a relatively simple methodology for the detection of microsatellite sequences in partial genetic libraries in plasmids, consisting mainly in a new DNA extraction protocol and the use of a probe (TG)7T to locate different types of microsatellites.Se presenta una metodología relativamente sencilla para la detección de secuencias microsatélites a partir de genotecas parciales en plásmidos, que consiste fundamentalmente en un nuevo protocolo de extracción de DNA y el empleo de una sonda (TG)7T para localizar diferentes tipos de microsatélites

A branch-point approximant for the equation of state of hard spheres

Using the first seven known virial coefficients and forcing it to possess two branch-point singularities, a new equation of state for the hard-sphere fluid is proposed. This equation of state predicts accurate values of the higher virial coefficients, a radius of convergence smaller than the close-packing value, and it is as accurate as the rescaled virial expansion and better than the Pad\'e [3/3] equations of state. Consequences regarding the convergence properties of the virial series and the use of similar equations of state for hard-core fluids in $d$ dimensions are also pointed out.Comment: 6 pages, 4 tables, 3 figures; v2: enlarged version, extension to other dimensionalities; v3: typos in references correcte

Conformational dissection of a viral intrinsically disordered domain involved in cellular transformation

Intrinsic disorder is abundant in viral genomes and provides conformational plasticity to its protein products. In order to gain insight into its structure-function relationships, we carried out a comprehensive analysis of structural propensities within the intrinsically disordered N-terminal domain from the human papillomavirus type-16 E7 oncoprotein (E7N). Two E7N segments located within the conserved CR1 and CR2 regions present transient α-helix structure. The helix in the CR1 region spans residues L8 to L13 and overlaps with the E2F mimic linear motif. The second helix, located within the highly acidic CR2 region, presents a pH-dependent structural transition. At neutral pH the helix spans residues P17 to N29, which include the retinoblastoma tumor suppressor LxCxE binding motif (residues 21-29), while the acidic CKII-PEST region spanning residues E33 to I38 populates polyproline type II (PII) structure. At pH 5.0, the CR2 helix propagates up to residue I38 at the expense of loss of PII due to charge neutralization of acidic residues. Using truncated forms of HPV-16 E7, we confirmed that pH-induced changes in α-helix content are governed by the intrinsically disordered E7N domain. Interestingly, while at both pH the region encompassing the LxCxE motif adopts α-helical structure, the isolated 21-29 fragment including this stretch is unable to populate an α-helix even at high TFE concentrations. Thus, the E7N domain can populate dynamic but discrete structural ensembles by sampling α-helix-coil-PII-ß-sheet structures. This high plasticity may modulate the exposure of linear binding motifs responsible for its multi-target binding properties, leading to interference with key cell signaling pathways and eventually to cellular transformation by the virus.Instituto de Física de Líquidos y Sistemas Biológico