ASSOCIATION BETWEEN MANDIBULAR CANAL COURSE AND INTERFORAMINAL AREA IN PANORAMIC RADIOGRAPHS FOR IMPLANT PLACEMENT

ABSTRACT Objective: The aim of this study was to evaluate the relationship of mandibular canal course with mental foramen localization on edentulous patients’ for implant placement. Material and Methods: This retrospective study was carried out on the panoramic radiographs of 788 edentulous patients. Horizontal measurements L (left mental foramen to the left mandibular ramus), R (right mental foramens to the right mandibular ramus), M (between the mental foramens) and vertical measurements D1 (mental foramen’s inferior border to the mandibular basis), D2 (mental foramen’s superior border to the alveolar crest) were digitally evaluated. Mandibular canals were classified into two types as linear and elliptic. Analysis of demographic data and correlations between canal course and linear measurements were carried out. Kolmogorov-Smirnov and Shapiro Wilks tests, Kruskal Wallis test, and Chi-squared test was used to compare the qualitative data (p <0.05). Results: There was a statistically significant difference between the D1/D2 mean values and the canal course according to the age groups. The rate of the elliptic canal course in the men (41.6%) was significantly higher than that in the women (26.6%). There was no statistically significant difference between the mean D1/D2, (R + L)/M and L/M values according to the canal course. Conclusions: Both elliptical and linear canal courses do not affect the interforaminal distances, resulting ineffective in the anteroposterior spread of implants in cases of interforaminal implant placement. Key Words: Mandibular canal, canal course, interforaminal area, canal anatomy, implant. ÖZET Amaç: Bu çalışmanın amacı dişsiz hastalarda implant uygulaması için mandibular kanal seyri ve mental foramen konumunun ilişkisinin değerlendirilmesidir. Gereç ve Yöntemler: Bu retrospektif çalışma 788 dişsiz hastanın panoramik radyografileri ile yürütülmüştür. Ölçümler horizontal ve vertikal şeklinde dijital olarak yapılmıştır. L (sol mental foramen ile sol ramus arası mesafe), R (sağ mental foramen ile sağ ramus arası mesafe), M (mental foramenler arası mesafe) horizontal ölçümler; D1 (mental foramenin alt sınırı ile basis mandibular arası mesafe) ve D2 (mental foramenin üst sınırı ile alveol kret tepesi arası mesafe) ise vertikal ölçümlerdir. Mandibular kanal seyri doğrusal ve eliptik olarak iki sınıfta incelenmiştir. Demografik veriler, kanal seyri ve dijital ölçümler arası ilişki değerlendirilmiştir. Kolmogorov-Smirnov ve Shapiro Wilks testleri, Kruskal Wallis testi, ve Ki-Kare testi niteliksel verilerin karşılaştırılmasında kullanılmıştır (p <0,05). Bulgular: Yaş grupları arasında D1/D2 oranları ve kanal seyri açısından istatsitiksel olarak anlamlı farklılık tespit edilmiştir. Kanal seyrinin eliptik görülme oranı erkeklerde (%41,6) kadınlardan (%26,6) anlamlı derecede yüksek bulunmuştur. Kanal seyrine gore D1/D2, (R+L)/M ve L/M ortalamaları açısından istatistiksel olarak anlamlı farklılık yoktur. Sonuç: Eliptik ve doğrusal kanal seyrinin interforaminal mesafeye herhangi bir etkisi yoktur, bu durum antero-posterior yönde interforaminal aralığa implant yerleştirilmesini etkilememktedir. Anahtar Kelimeler: Mandibular kanal, kanal seyri, interforaminal bölge, kanal anatomisi, implant

Ki-67 and MCM-2 in Dental Follicle and Odontogenic Cysts: The Effects of Inflammation on Proliferative Markers

The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study consisted of 70 DFs and 20 odontogenic cysts (radicular cyst (RC), dentigerous cyst (DC) and keratocytic odontogenic tumor (KCOT) located at posterior mandibular region. Histological findings of inflammation for all specimen and mucous cell prosoplasia, squamous metaplasia, glandular epithelium for all DFs were stained with hematoxyline and eosin, periodic acid schiff, alcian blue, and mucin. Epithelial cell proliferation was determined by using immunohistochemical labeling for Ki-67 and MCM-2. The histologic examinations showed 16% mucous cell prosoplasia, 54% squamous metaplasia, 20% glandular epithelium, 37% inflammation. Inflammation was detected in all RCs and %62 in DF, %43 in DC and KCOT. Positive correlation was found between the inflammation of DF and odontogenic cysts (P < 0.01). The mean Ki-67 and MCM-2 expressions were found 9, 64 +/- 5, 99 and 6, 34 +/- 3, 81 in DF, 11, 85 +/- 9, 01 and 13, 6 +/- 9, 94 in odontogenic cysts, respectively. While the mean Ki-67 expressions were statistically significant in DF and KCOT (P < 0.01), MCM-2 were significant in RC and KCOT (P < 0.01). MCM-2 expresion in RCs were statistically significant than KCOT (P < 0.01). The results of this study indicated that the higher MCM-2 expressions in RC than the KCOT might be related to the inflammation and this protein might be more sensitive to inflammation

Ki-67 and MCM-2 in Dental Follicle and Odontogenic Cysts: The Effects of Inflammation on Proliferative Markers

The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study consisted of 70 DFs and 20 odontogenic cysts (radicular cyst (RC), dentigerous cyst (DC) and keratocytic odontogenic tumor (KCOT) located at posterior mandibular region. Histological findings of inflammation for all specimen and mucous cell prosoplasia, squamous metaplasia, glandular epithelium for all DFs were stained with hematoxyline and eosin, periodic acid schiff, alcian blue, and mucin. Epithelial cell proliferation was determined by using immunohistochemical labeling for Ki-67 and MCM-2. The histologic examinations showed 16% mucous cell prosoplasia, 54% squamous metaplasia, 20% glandular epithelium, 37% inflammation. Inflammation was detected in all RCs and %62 in DF, %43 in DC and KCOT. Positive correlation was found between the inflammation of DF and odontogenic cysts (P<0.01). The mean Ki-67 and MCM-2 expressions were found 9,64±5,99 and 6,34±3,81 in DF, 11,85±9,01 and 13,6±9,94 in odontogenic cysts, respectively. While the mean Ki-67 expressions were statistically significant in DF and KCOT (P<0.01), MCM-2 were significant in RC and KCOT (P<0.01). MCM-2 expresion in RCs were statistically significant than KCOT (P<0.01). The results of this study indicated that the higher MCM-2 expressions in RC than the KCOT might be related to the inflammation and this protein might be more sensitive to inflammation

determination of incidence of complications and life quality after mandibular impacted third molar surgery

Ama&ccedil;: Bu &ccedil;alışmanın amacı; mandibuler g&ouml;m&uuml;l&uuml; &uuml;&ccedil;&uuml;nc&uuml; molar diş cerrahisi sonrası gelişen komp-likasyonların g&ouml;r&uuml;lme sıklığı, şiddeti ve &ccedil;eşidinin saptanması, nedenlerin araştırılması, g&ouml;r&uuml;len komp-likasyonların &ouml;nlenmesi ve hastaların cerrahi operasyon sonrası yaşam kalitesinin belirlenmesidir. Gere&ccedil; ve Y&ouml;ntem: &Ccedil;alışma, yaşları 16 ile 83 arasında değişen, 77&#39;si bayan, 28&#39;i erkek toplam 105 hastanın 121 mandibuler g&ouml;m&uuml;l&uuml; &uuml;&ccedil;&uuml;nc&uuml; molar dişi &uuml;zerinde y&uuml;r&uuml;t&uuml;ld&uuml;. T&uuml;m hastaların yaşı, cinsiyeti, sistemik durumu, k&ouml;t&uuml; alışkanlıkları, ağız hijyenleri, oral kontraseptif kullanımı ve menst&uuml;rasyon d&ouml;nemleri ayrıca mandibuler g&ouml;m&uuml;l&uuml; &uuml;&ccedil;&uuml;nc&uuml; molar sınıflaması, ağrı, &ouml;dem, trismus, parestezi gibi postoperatif komplikasyonlar kaydedildi. Bulgular: &Ouml;dem varlığı (94, 5.5&plusmn;3.06, p=0.004) ve kanama komplikasyonu arasında (29, 6.24&plusmn;2.77, p=0.019), operasyon s&uuml;resi ile &ouml;dem varlığı arasında (94, 30.65&plusmn;15.49, p=0.005) ve operasyon s&uuml;resi ile parestezi komplikasyonu arasında (10, 41.2&plusmn;15.15, p=0.006) istatistiksel olarak anlamlı bir fark kaydedildi. Sonu&ccedil;: Yaşam kalitesinin k&ouml;t&uuml;leşmesine neden olan postoperatif bulgular, ağrı, &ouml;dem, trismus ve parestezi olup, dikkatli bir cerrahi teknik, operatif &ouml;zen ve hastaların postoperatif &ouml;nerileri uygulaması komplikasyonların sıklığını ve şiddetini azaltacaktır. Anahtar kelimeler: Mandibuler g&ouml;m&uuml;l&uuml; &uuml;&ccedil;&uuml;nc&uuml; molar, komplikasyon, g&ouml;rsel analog skala, yaşam kalite

Determination of potential cellular proliferation in the odontogenic epithelia of the dental follicle of the asymptomatic impacted third molars

Purpose: The aim of this study is to determine the proliferative potentials of dental follicles (DF) of radiographically asymptomatic impacted third molar teeth by using Ki-67 and mini-chromosome maintenance protein 2 (MCM-2) proliferation markers, and to discuss whether there is any necessity for the removal of all impacted third molars by detecting the potential of the developing cysts and tumors; of its DF

The Effect of Bovine Bone Graft With or Without Platelet-Rich Plasma on Maxillary Sinus Floor Augmentation

WOS: 000296071200015PubMed ID: 21798642Purpose: The purpose of this study was to compare Unilab Surgibone (USB) (Mississauga, Ontario, Canada), a bone xenograft (bovine), with platelet-rich plasma (PRP) and USB without PRP to augment the human maxillary sinus in preparation to receive dental implants. Patients and Methods: Patients who had bilateral pneumatized maxillary sinuses were included. Sinuses on one side were augmented with the USB-PRP combination and formed the study group, whereas the opposite-side sinuses were augmented with USB alone and served as controls. Bone biopsy specimens were taken during implant placement at 6.8 +/- 0.9 months after maxillary sinus floor augmentation. Resonance frequency analysis measurements were performed at implant placement (first control) and before the prosthetic stage (second control), at 6.5 +/- 0.7 months after implant surgery. Results: There were 10 patients (7 men and 3 women; mean age, 53.7 +/- 0.8 years). Integration between new bone and residual grafts was histologically observed in all samples. The volumes of soft tissue were 59.9% +/- 7.5% and 57.8% +/- 4.4% in the control and study groups, respectively; residual graft, 21.9% +/- 6.6% and 23.6% +/- 5.9%, respectively; new bone, 15.8% +/- 4.8% and 16.0% +/- 3.8%, respectively; and trabecular bone, 64.7% +/- 22.5% and 69.1% +/- 18.6%, respectively. A positive correlation was found between new bone volume and trabecular bone volume (P = .0001). The mean Implant Stability Quotient (ISQ) values were 71.7 +/- 4.9 and 70.3 +/- 5.7 in the control and study groups, respectively, at first control and 75.4 +/- 6.4 and 74.4 +/- 6.4, respectively, at second control. The mean ISQ values at second control in both groups were significantly higher than at first control (P = .043 and P = .028, respectively). No statistically significant differences were observed between groups (P > .05). Conclusion: The combination of USB and PRP does not have any effect on new bone formation and implant stabilization. (C) 2011 American Association of Oral and Maxillofacial Surgeons J Oral Mcaillofac Surg 692537-2547, 201

DENTAL PATIENTS’ KNOWLEDGE AND AWARENESS ABOUT TRANSMISSION WAYS OF ACQuIRED IMMUNE DEFICIENCY SYNDROME (AIDS)

Purpose: The aim of this study was to evaluate the patients’ attitude, knowledge and awareness about HIV/AIDS. And secondary aim was to assess the need for further education about HIV/AIDS. Materials and Methods: A questionnaire of 39 items was used to evaluate the patients’ knowledge. 301 patients were included (mean age 37.12 ±7.85 years, 41.5% male, 58.5% female) in the study. Results were calculated by Students t-test, Chi-square test, Fisher’s exact test. Results: Most of the patients had accurate knowledge about transmission ways, however transmission through breastfeeding (31.6%), public restrooms (44.9%), and insects and mosquitos bite (47.2%) were less recognized. Saliva (32.2%), urine (36.9%), tears (58.5%), sweat (54.5%), breast milk (30.6%), feces (36.9%) and cerebrospinal fluid (7.3%) were less recognized body fluids. Generally university and postgraduate educated patients had more accurate knowledge than other groups. 63.1% of patients thought that they need further education about HIV/AI DS. Conclusion: The results of this study showed that the knowledge level about HIV/AIDS was almost agreeable. However, the patients had deficiencies with respect to their knowl-edge. Therefore the authors of this study believe that there must be education programs related to HIV/AIDS

Implant stability outcomes after immediate and delayed revascularized free fibula flaps: a preliminary comparative study

Capar, Gonca Duygu (Trakya author)Purpose: This pilot study investigated the retrospective outcomes of implants placed immediately or with a delayed protocol in revascularized free fibula flaps (FFF). Materials and Methods: Patients undergoing FFF between 2014 and 2017 were included in the study. Implants were inserted either immediately or 23.63 +/- 10.61 months after reconstructive surgery. Resonance frequency analyses were recorded at the time of implant placement (first control) and 4 months postoperatively while uncovering and screwing the gingiva formers (second control). The statistical significance level was set at P .05). Conclusion: High stability scores similar to alveolar bone could be achieved by both immediate and delayed implant placement. Bicortical implantation results in better implant stability