185 research outputs found

    Hybrid features-based prediction for novel phish websites

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    Phishers frequently craft novel deceptions on their websites and circumvent existing anti-phishing techniques for insecure intrusions, users’ digital identity theft, and then illegal profits. This raises the needs to incorporate new features for detecting novel phish websites and optimizing the existing anti-phishing techniques. In this light, 58 new hybrid features were proposed in this paper and their prediction susceptibilities were evaluated by using feature co-occurrence criterion and a baseline machine learning algorithm. Empirical test and analysis showed the significant outcomes of the proposed features on detection performance. As a result, the most influential features are identified, and new insights are offered for further detection improvement

    ON DIRECT PRODUCT pure − 1 − 2 − 3 SUBGROUPS IN ABELIAN GROUP Gn×Gm

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    In this paper, we shall define new subgroups which are called pure−1−2−3 in abelian groups Gn×Gm for all n,m∈N which are a family of pure subgroups. In[1],[2]H.M.A.Abdullah  gave the some general properties of pure− 1−2−3 in abelian group G, but here, we shall prove more than properties on this subgroups in ModGn×Gm, which are not valid for pure subgroups

    Zinc Oxide Hydrogen Sulfide Removal Catalyst/ Preparation, Activity Test and Kinetic Study

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    Hydrogen sulfide removal catalyst was prepared chemically by precipitation of zinc bicarbonate at a controlled pH. The physical and chemical catalyst characterization properties were investigated. The catalyst was tested for its activity in adsorption of H2S using a plant that generates the H2S from naphtha hydrodesulphurization and a unit for the adsorption of H2S. The results comparison between the prepared and commercial catalysts revealed that the chemical method can be used to prepare the catalyst with a very good activity.<br />It has observed that the hydrogen sulfide removal over zinc oxide catalyst follows first order reaction kinetics with activation energy of 19.26 kJ/mole and enthalpy and entropy of activation of 14.49 kJ/mole and -220.41 J/mole respectively.<br /

    Effect of shark cartilage derived protein on the NK cells activity

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    Context: Shark cartilage has been used for its beneficial effects on various diseases. There are evidences, that shark cartilage stimulates cellular and humoral immune responses, which makes it an anti-tumor and immunomodulator candidate. Objective: The immunostimulatory effect of shark cartilage derived proteins on the cytotoxic activity of natural killer (NK) cells from healthy human peripheral blood mononuclear cells was studied. Material and methods: The shark cartilage was extracted and its bioactive proteins were purified using ion-exchange chromatography (DE-52) and sequential fractionation on Amicon ultrafiltration membranes. The effect of each protein fraction on the modulation of cytotoxic activity of NK cells, as effectors, against K562, as target cells, was assayed by enzymatic lactate dehydrogenase test. Results: The most immunostimulatory effect on the cytotoxic activity of NK cells was observed for AR10 fraction, containing proteins with molecular weight of about 14.5kDa on the reducible discontinuous sodium dodecyl sulfate polyacrylamide gel electrophoresis. Discussion: Among the examined shark cartilage derived proteins, the most immunostimulatory effects on the NK cells cytotoxicity was found for AR10 fraction with molecular weight of about 14kDa. We propose—the direct interactions of shark cartilage derived proteins with NK cells surface receptors may lead to the enhancing in the cytotoxic activity of NK cells. Conclusion: Thus AR10 fraction, proteins of about 14.5kDa, has a novel immunostimulatory effect on the NK cells activity in vitro and if confirmed by in vivo trials, it may lead to its future clinical applications as, immunotherapy of cancer, HIV, and augmentation of host immune system related immunodeficiency disorders. Keywords: Immunostimulation, purification, shark cartilage, K562, NK cel

    A Review of Enzymatic Transesterification of Microalgal Oil-Based Biodiesel Using Supercritical Technology

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    Biodiesel is considered a promising replacement to petroleum-derived diesel. Using oils extracted from agricultural crops competes with their use as food and cannot realistically satisfy the global demand of diesel-fuel requirements. On the other hand, microalgae, which have a much higher oil yield per hectare, compared to oil crops, appear to be a source that has the potential to completely replace fossil diesel. Microalgae oil extraction is a major step in the overall biodiesel production process. Recently, supercritical carbon dioxide (SC-CO2) has been proposed to replace conventional solvent extraction techniques because it is nontoxic, nonhazardous, chemically stable, and inexpensive. It uses environmentally acceptable solvent, which can easily be separated from the products. In addition, the use of SC-CO2 as a reaction media has also been proposed to eliminate the inhibition limitations that encounter biodiesel production reaction using immobilized enzyme as a catalyst. Furthermore, using SC-CO2 allows easy separation of the product. In this paper, conventional biodiesel production with first generation feedstock, using chemical catalysts and solvent-extraction, is compared to new technologies with an emphasis on using microalgae, immobilized lipase, and SC-CO2 as an extraction solvent and reaction media

    IMPLEMENTASI PROGRAM KAWASAN RUMAH PANGAN LESTARI MELALUI SISTEM HIDROPONIK TANAMAN HORTIKULTURA DI DESA MANGKUNG

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    ABSTRAKDesa Mangkung memiliki lahan pekarangan yang cukup luas, namun belum dikelola dengan baik oleh masyarakat. Padahal, lahan pekarangan bisa dijadikan sebagai Kawasan Rumah Pangan Lestari yang dapat menunjang kebutuhan pangan dan meingkatkan pendapatan masyarakat. Kegiatan ini bertujuan untuk memberikan wawasan, pemahaman, serta informasi kepada masyarakat Desa Mangkung tentang pengelolaan lahan pekarangan melalui budidaya tanaman hortikultura dengan sistem hidroponik. Kegiatan ini dilaksanakan dalam tiga tahapan yaitu observasi, sosialisasi, dan pelaksanaan kegiatan. Jenis tanaman yang dibudidaya yaitu selada (Lactuca sativa), pakcoy (Brassica rapa), dan kangkung (Ipomea aquatic Forsk) dengan media tanam berupa rockwool dan pupuk kompos organik yang dibuat dengan memanfaatkan limbah kotoran ternak sapi masyarakat setempat. Kegiatan ini mendapatkan respon yang baik serta dukungan dari masyarakat setempat. Kegiatan ini diharapkan menjadi alternatif yang baik bagi masyarakat dalam memanfaatkan lahan pekarangan yang tidak dimaksimalkan dengan optimal. Selain itu, kedepannya masyarakat dapat secara mandiri memenuhi kebutuhan pangan berupa sayur-sayuran serta mampu meningkatkan pendapatan rumah tangga menuju masyarakat yang sehat, mandiri, dan sejahtera. Kata kunci: hortikultura; rumah pangan lestari; sistem hidroponik ABSTRACTMangkung Village has a very large parkland but has not been optimized very well by the local community. Instead, the land can be used as a home for food, which can support food needs and increase the community’s income. This activity aimed to give the community knowledge and understanding about how to utilize parkland land by cultivating horticultural plants with hydroponic sistems. This activity was done in three steps: observation, socialization, and implementation. The hydroponic sistem used uses three types of crops cultivated namely selada (Lactuca sativa), pakcoy (Brassica rapa), and kangkung (Ipomea aquatic Forsk) with the medium of rockwool and organic composite fertilizer made using local cattle livestock waste. This activity has received a good response and support from the local community. It would be a good alternative for the community in exploiting the land that is not maximized optimally. In addition, the community can supply food (vegetables) independently and can increase household income toward a self-sufficient, healthy, and prosperous society. Keywords: horticulture; sustainable food house; hydroponic siste

    Opposite changes in the expression of clathrin and caveolin-1 in normal and cancerous human prostate tissue: putative clathrin-mediated recycling of EGFR

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    Endocytosis, an important macromolecule uptake process in cells, is known to be dysregulated in cancer. Clathrin and caveolin-1 proteins play a major role in receptor-mediated endocytosis. We have used a quantitative, unbiased and semi-automated method to measure in situ protein expression of clathrin and caveolin-1 in cancerous and paired normal (cancer adjacent, non-cancerous) human prostate tissue. There was a significant (p < 0.0001) increase in the expression of clathrin in prostate cancer samples (N = 29, n = 91) compared to normal tissue (N = 29, n = 67) (N = number of patients, n = number of cores in tissue arrays). Conversely, there was a significant (p < 0.0001) decrease in expression of caveolin-1 in prostate cancer tissue compared to normal prostate tissue. The opposite change in expression of the two proteins was highly correlated to increasing cancer aggressiveness. There was also a concurrent increase in the expression of epidermal growth factor receptor (EGFR), a key receptor in carcinogenesis, with clathrin in prostate cancer tissue, indicating recycling of EGFR through clathrin-mediated endocytosis (CME). These results indicate that in prostate cancer, caveolin-1-mediated endocytosis (CavME) may be acting as a brake and increase in CME may facilitate tumorigenicity and aggressiveness of prostate cancer through recycling of EGFR. Changes in the expression of these proteins can also potentially be used as a biomarker for prostate cancer to aid in diagnosis and prognosis and clinical decision-making

    Female reproductive tract anatomy of the endangered Arabian oryx (Oryx leucoryx) in Jordan

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    Female reproductive anatomy of the Arabian oryx is unknown. In this study, reproductive tracts of seven female Arabian oryx (aged 2 to 7 years) were examined to characterize their reproductive anatomy. Observations and measurements were obtained in situ from dead animals during necropsy. Animals were allocated into two groups: cycling (n=3; follicles or corpora lutea present) and not-cycling (n=4; follicles or corpora lutea absent). Different reproductive tract segments for each animal in both groups were measured using a digital caliper. The mean, SD and range for each reproductive tract segment were generated and compared between groups. Female oryx reproductive anatomy share some anatomical characteristics with that of domestic ruminants except that the oryx uterus has no distinct uterine body and the cervix has two internal openings for each respective uterine horn. In addition, there were more than 8 rows of caruncles within each uterine horn. There were significant differences in the length and width (P&lt;0.05), but not in height, of both the right and left ovaries between cycling and not-cycling animals (P&gt;0.05). Posterior and anterior vaginal lengths varied between cycling and not-cycling groups (P&lt;0.05). Length of right and left oviducts, left and right uterine horns, cervix and vulva did not vary between cycling and not-cycling groups (P&gt;0.05). Defining this unique morphology of female Arabian oryx reproductive anatomy will help in the development of appropriate reproductive techniques in order to propagate this endangered species and control its reproduction
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