Internet adiction disorder o internet related psychopathology?

In this paper we present the state of the art of the Internet Addiction Disorder (IAD) and some alternative theoretical models critical with the category of Internet addiction. The review of the literature shows that IAD is an umbrella concept, and that there is not a common definition. In our society in which a great deal of activity is carried out online, it is not useful to talk about a generic Internet addiction. In this paper we show the theoretical and methodological issues of IAD construct that induced some researchers to shift the focus to specific psychopathology related to the Internet. New systematic studies on specific activities about dysfunctional conducted online are necessary. Prevention and treatment strategies should lean towards more functional navigation styles rather than to a general reduction of Internet use

Real-life use of Doravirine in treatment-experienced people living with HIV: A multicenter Italian study

Use of doravirine (DOR), a new nonnucleoside reverse-transcriptase inhibitors recently approved for HIV treatment, is still unclear in clinical practice and real-life data are scarce. We retrospectively investigated the rationale for switching people with HIV to DOR-containing/-based regimens in a real-life cohort. Among 132 patients (68.9% males, median age 56 years), the main reasons to start DOR were prevention of toxicities (39.4%) and dyslipidemia (18.2%). DOR was combined with integrase inhibitors in 40.9% cases, and in 25.7% of patients, DOR was prescribed without availability of a genotypic resistance test. Twenty-four weeks after the switch to DOR-containing/-based regimens, no significant changes in CD4+ T-cell count, CD4/CD8 ratio, detectable HIV-RNA, serum creatinine levels, and body weight were detected. By contrast, a significant reduction in lipids (both cholesterol and triglycerides) was observed in 52 patients for whom a follow-up assessment was available (P =.008 and.01, respectively). Our data confirmed that switching to DOR-containing/-based regimens may have a favorable impact on lipid profile and a neutral impact on weight gain. However, more data are needed to support its use in patients who do not have a genotypic test available or have an extensive nonnucleoside reverse-transcriptase inhibitors-associated resistance, as well as its use in a dual regimen, especially in combination with second-generation integrase inhibitors

Uro-genital schistosomiasis screening in Italian subjects exposed to freshwater of Cavu River, Corsica (France)

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RE:Schistosomiasis screening of travelers to Corsica, France

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