Mathematical modelling of heating and evaporation of a spheroidal droplet

Objective: Dialysis patients frequently report a change of taste that is reversible after renal transplantation, suggesting that uremic toxins may negatively influence taste. Currently, frequent nocturnal home hemodialysis (NHHD) is the most effective method of hemodialysis, and is associated with the lowest levels of uremic toxins. We studied preferences for various foods as an indicator of taste perception. We questioned whether food preference differs between NHHD patients and those on conventional hemodialysis. Design and Patients: In this transverse, cross-sectional pilot study, we assessed food preference by means of a questionnaire for patients on NHHD (n=6; 8 hours of dialysis per night, for 5 or 6 nights a week) and 3 age-matched and sex-matched control groups: chronic home hemodialysis patients (HHD; n=9; 4 to 5 hours of dialysis per day, 3 days a week), chronic in-center hemodialysis patients (CHD; n=18; 4 to 5 hours of dialysis per day, 3 days a week), and healthy control subjects (HC; n=23). Results: Mean scores for food preference did not differ between groups (P=.32). Similarly, the preference for product groups did not differ between groups. On an individual product level, we found only minor differences. The NHHD patients had a preference for savory snacks, as did the HC and CHD groups, whereas the HHD group had a preference for sweet snacks (P <.05). Hemodialysis patients reported dry mouth more often than did the HC patients (P <.05). Conclusions: Frequent NHHD has no major impact on food preference. The change in taste reported by NHHD patients is not related to their particular food preferences. (C) 2010 by the National Kidney Foundation, Inc. All rights reserved

The first example of an intramolecular Diels-Alder furan (IMDAF) reaction of iminium salts and its application in a short and simple synthesis of the isoindolo[1, 2-a]isoquinoline core of the jamtine and hirsutine alkaloids

1-(2-Furyl)-3, 4-dihydroisoquinolines, easily prepared from readily available phenethylamines undergo tandem alkylation/[4+2]-cycloaddition with allyl halides. The reaction proceeds via 2-allyl-1-furyl-3, 4- dihydroisoquinolinium salt formation and subsequent intramolecular exo-Diels-Alder reaction of furan with the allyl fragment (IMDAF reaction). The adducts formed include the basic structural element of the isoindolo[1, 2-a]isoquinoline alkaloids jamtine and hirsutine. © 2010 Elsevier Ltd. All rights reserved

The first example of an intramolecular Diels-Alder furan (IMDAF) reaction of iminium salts and its application in a short and simple synthesis of the isoindolo[1, 2-a]isoquinoline core of the jamtine and hirsutine alkaloids

1-(2-Furyl)-3, 4-dihydroisoquinolines, easily prepared from readily available phenethylamines undergo tandem alkylation/[4+2]-cycloaddition with allyl halides. The reaction proceeds via 2-allyl-1-furyl-3, 4- dihydroisoquinolinium salt formation and subsequent intramolecular exo-Diels-Alder reaction of furan with the allyl fragment (IMDAF reaction). The adducts formed include the basic structural element of the isoindolo[1, 2-a]isoquinoline alkaloids jamtine and hirsutine. © 2010 Elsevier Ltd. All rights reserved

The intramolecular Diels-Alder vinylfuran (IMDAV) reaction: a short approach to aza-analogues of pinguisane-type sesquiterpenes

Abstract The reaction of readily accessible (3-furyl)allylamines with maleic anhydride, followed by a domino sequence involving acylation/cycloaddition/proton shift steps, led to the formation of furo[2,3-f]isoindoles - the aza-analogs of pinguisane-type sesquiterpenes. The key intramolecular Diels-Alder vinylfuran (IMDAV) reaction proceeded under mild conditions, with high levels of diastereoselectivity and satisfactory yields. © 2015 Elsevier Ltd

Synthesis of N,N′-Dialkylated Cyclohexane-1,2-diamines and Their Application as Asymmetric Ligands and Organocatalysts for the Synthesis of Alcohols

A series of N,N′-dialkylated derivatives of (1R,2R)-cyclohexane-1,2-diamine were synthesized, and a new approach to the one-pot preparation of this type of amine was demonstrated. The prepared diamines were used as organocatalysts for the two-step synthesis of α-hydroxy γ-keto esters from arenes, chlorooxoacetates, and ketones; they were also used as chiral ligands for Meervein-Ponndorf-Verley reductions and Henry reactions. © Georg Thieme VerlagStuttgart · New York

The intramolecular Diels-Alder vinylfuran (IMDAV) reaction: a short approach to aza-analogues of pinguisane-type sesquiterpenes

Abstract The reaction of readily accessible (3-furyl)allylamines with maleic anhydride, followed by a domino sequence involving acylation/cycloaddition/proton shift steps, led to the formation of furo[2,3-f]isoindoles - the aza-analogs of pinguisane-type sesquiterpenes. The key intramolecular Diels-Alder vinylfuran (IMDAV) reaction proceeded under mild conditions, with high levels of diastereoselectivity and satisfactory yields. © 2015 Elsevier Ltd

Computer simulation of multispectral the target and background situation when you hover on ground targets

Запропоновано методику отримання характеристик розсіювання складних радіолокаційних об’єктів шляхом комп’ютерного моделювання мультиспектральної цілефонової обстановки (ЦФО) при наведенні (самонаведенні) ракет на наземні цілі на основі аналізу фізичних закономірностей формування випромінених, розсіяних і відбитих ціллю сигналів в різних діапазонах спектру електромагнітних хвиль, а також їх кореляційного взаємозв’язку з характеристиками формоутворюючої поверхні цілі. Методику апробовано на моделях об’єктів з різною геометрією формоутворюючої поверхні.Предложено методику получения характеристик рассеивания сложных радиолокационных объектов путем компьютерного моделирования мультиспектральной целефоновой обстановки (ЦФО) при наведении (самонаведении) ракет на наземные цели на основе анализа физических закономерностей формирования излученных, рассеянных, и отраженных наземной целю сигналов в различных диапазонах спектра электромагнитных волн, а также их корреляционной взаимосвязи с характеристиками формообразующей поверхности цели. Методика апробирована на моделях объектов с различной геометрией формообразующей поверхности.The technique of computer simulation of multispectral the target and background environment hover (homing) missiles at ground targets based on analysis of the physical laws governing the formation of the radiation scattered and reflected terrestrial purpose to signals in different bands of the electromagnetic spectrum, as well as their correlation relationship with the characteristics of the molding surface purpose. The method was tested on models of objects with different geometry of the molding surface

Synthesis of N,N′-Dialkylated Cyclohexane-1,2-diamines and Their Application as Asymmetric Ligands and Organocatalysts for the Synthesis of Alcohols

A series of N,N′-dialkylated derivatives of (1R,2R)-cyclohexane-1,2-diamine were synthesized, and a new approach to the one-pot preparation of this type of amine was demonstrated. The prepared diamines were used as organocatalysts for the two-step synthesis of α-hydroxy γ-keto esters from arenes, chlorooxoacetates, and ketones; they were also used as chiral ligands for Meervein-Ponndorf-Verley reductions and Henry reactions. © Georg Thieme VerlagStuttgart · New York