Le management multi-projet dans les petites et moyennes entreprises

Dans un contexte de mondialisation et de croissance économique, les organisations ont depuis toujours et de plus en plus le souci de la bonne gestion, raison pour laquelle elles tentent tous les jours de mettre en application les méthodes de bonnes pratiques dans le but d’atteindre les objectifs qu’elles se fixent. L’organisation, tout au long de son cycle de vie, en plus de la gestion de ses activités courantes (opérationnelles), doit aussi mener à bien ses projets. La gestion de projet compte plusieurs approches, parmi lesquelles on retrouve le management multi-projet. D’après Fernez-Walch et Triomphe (2004), le management multi-projet « vise à gérer de façon globale un ou plusieurs ensembles de projets, en tenant compte des interdépendances entre les projets d'un même ensemble ». De nombreuses recherches ont porté sur le management multi-projet dans le cas des grandes entreprises multinationales et des organismes gouvernementaux, faisant part des outils, techniques et pratiques mis en place dans ces grosses boîtes, ainsi que des difficultés auxquelles elles font face. Cependant, peu de recherches se sont penchées sur le cas des organisations, à plus petite structure, disposant de ressources plus modestes, comme les petites et moyennes entreprises (PME). D’où notre question de recherche : comment les PME, avec ce qui les caractérise, font du management multi-projet ? L’approche interprétative est la démarche qui nous permettra de répondre au mieux et de façon cohérente aux questions qui nous animent. Afin d’apporter des réponses à notre question de recherche, nous nous sommes fixés comme objectif général, d’examiner les méthodes de management multi-projet utilisées dans les petites et moyennes entreprises, à travers d’autres objectifs spécifiques. C’est à travers une méthode de recherche exploratoire que notre étude s’inscrivant dans une typologie d’approche qualitative va être réalisée. Des entrevues semi-dirigées avec différents responsables de projet de petites et moyennes entreprises de la ville du Saguenay ont été menées selon une démarche éthique en vue de collecter des données qui ont été par la suite traitées, analysées et interprétées à l’aide du logiciel d’analyse qualitative Nvivo 10 pour en déduire les résultats. Les résultats tirés de notre démarche scientifique, nous permettent d’affirmer que les petites et moyennes entreprises évoluant dans le multi-projet mettent en application la quasi-totalité des processus de management de projet proposés par le PMBOK, comme les grandes entreprises, même si elles ne le font pas toujours de façon formelle, structurée et ne les maitrisent pas toutes. Il nous est ressorti aussi que dans leur management multi-projet, les responsables de projet dans les PME rencontrent des difficultés semblables à celles de leurs confrères travaillant dans les grandes entreprises. Malgré les limites de notre projet de recherche, nous avons pu formuler des suggestions de bonnes pratiques, afin aider les responsables de projet des PME dans leur management multi-projet

Geographical Distribution Characteristics of Ethnic-Minority Villages in Fujian and Their Relationship with Topographic Factors

The geographical distribution characteristics of villages characterised by ethnic minorities are determined by the selection of the site when the village was initially established. The location of inherited and well-preserved minority villages must be exceptionally compatible with the natural terrain, with a logical relationship. Nonetheless, the issue of village location, which is directly related to the development of the features of the geographical distribution, has received little attention from scholars. The average nearest proximity index, Voronoi, kernel density analysis, proximity analysis, and the Geographical Detector (GeoDetector) were used to analyse the geographic distribution characteristics of villages and their correlation with terrain, as well as the difference between the influence of each terrain factor. The findings indicated the following. (1) The geographical distribution of minority villages in Fujian Province is of the agglomeration type, with a significant “mononuclear” feature, and the topography has a facilitating effect on the clustering distribution of villages. (2) The geographical distribution of minority villages in each city of Fujian Province coexisted with the agglomeration type and the dispersion type, and the role of topography in promoting the agglomeration-type distribution of villages was not affected by the distribution density of villages. (3) The site selection of Fujian-minority villages is characterised by medium altitude, moderate slope, sun exposure, and no obvious hydrophilicity. Minority villages are mainly located in areas with an elevation of 202–647 m; a slope of 6–15°; a flat land aspect with a south slope, southeast slope, or southwest slope; and distance of 500–1500 m from 5–20 m wide rivers of level 2. (4) The site selection of Fujian minority villages is influenced by various topographic factors, such as elevation, slope, aspect, river buffer, river width, and river level, among which river width has the most substantial effect. (5) All topographic factors have a two-factor enhancing relationship with each other, aspect and slope have the most substantial effect and play a dominant role in site selection. The research findings illuminate the internal logic of the geographical distribution differentiation of villages characterised by ethnic minorities, which is critical for promoting the protection of modern ethnic-minority villages

Multiparity and Breast Cancer Risk Factor among Women in Burkina Faso

The relative lack of information on breast cancer etiology in Burkina Faso led us to undertake the present work to highlight risk factors. This prospective study was conducted using a questionnaire between January 2015 and February 2016 on women admitted to Yalgado OUEDRAOGO hospital, for consultation or supervision. The characteristics of multiparous breast cancer patients (n = 44) were compared with their non-multiparous counterparts (n = 36). The study found that increased risk of breast cancer among non-multiparous cases was related to body mass index (BMI) (p <0.001), age at menopause (p <0.004) and use of oral contraception (p <0.021) while abortion (p <0.002) was a risk factor among multiparous cases. These results suggest that even if multiparity is associated with a decreased risk in some women, avoidance of abortion during reproductive life should be recommended. The results provide preliminary information, which now need to be supplemented by survey of a larger sample in the national territory.Peer reviewe

Relationship between soil water content and crop yield under sahelian climate conditions: case study of Tougou experimental site in Burkina Faso

This study aims at assessing the relationship between soil water stock and the yield of agricultural practices in Tougou catchment located in northern Burkina Faso. It is a region that has experienced a significant and continuous degradation of its natural resources, especially soils, due to the climate variability and the rapid increase of the population. Areas allocated to subsistence agriculture are increasing at the expense of pastoral land. This degradation causes a change in processes and mechanisms that control ecological systems. In order to provide solutions to this issue, some agricultural practices have been implemented to improve crop yield. This is particularly the case of traditional techniques:za, stony line and half-moon, which can significantly improve the soil infiltration capacity and yield. Daily monitoring of soil moisture and pressure in experimental plots based on these agricultural practices show that half-moon and Za¯ provided good yield with 2180kg / ha and 1070 kg / ha respectively compared to that of the control plot with about 480 kg/ha. These important yields are due in large part to the improvement of the retention capacity of these soils, thus giving to crops the necessary water need for their development even in drought period

Molecular diagnosis of COVID-19 in Burkina Faso: successful challenge

COVID-19 has worsened the health situation in Burkina Faso. In fact, the country has known a peak of the second wave, which began in November, and ended around January 2021. Biological diagnosis has played a key role in the management of COVID-19. The aim of this review paper is to address the practical aspects that laboratories have faced in order to meet the challenge of SARS-CoV-2 diagnosis in Burkina Faso. According to international requirements, Burkina Faso has used real-time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) as the “gold standard” for the diagnosis of COVID-19. From March 9, 2020 to July 31, 2021, in Burkina Faso, laboratories involved in COVID-19 diagnosis analyzed 226,189 samples by molecular tests and 2, 352 samples by rapid antigenic tests, whose peak was in January 2021 with 35,984 samples analyzed. The daily average rate of samples analysis was 456.02 tests. The majority of the individuals requesting COVID-19 tests were travelers (62.00%), followed by contact cases (18.42%), suspected cases (7.95%), voluntary screening (7.57%), and 4.06% of other applicants consisting of health care personnel and at-risk patients. In terms of prevention, vaccines are being administered to the general population. However, some efforts must be made to provide automated sample analysis equipment and complete sequencing of SARS-CoV-2 remains among the challenges

Evaluating survey designs for targeting preventive chemotherapy against Schistosoma haematobium and Schistosoma mansoni across Sub-Saharan Africa: a geostatistical analysis and modelling study

Abstract Background Schistosomiasis control programmes primarily use school-based surveys to identify areas for mass drug administration of preventive chemotherapy. However, as the spatial distribution of schistosomiasis can be highly focal, transmission may not be detected by surveys implemented at districts or larger spatial units. Improved mapping strategies are required to accurately and cost effectively target preventive chemotherapy to remaining foci across all possible spatial distributions of schistosomiasis. Methods Here, we use geostatistical models to quantify the spatial heterogeneity of Schistosoma haematobium and S. mansoni across Sub-Saharan Africa using the most comprehensive dataset available on school-based surveys. Applying this information to parameterise simulations, we assess the accuracy and cost of targeting alternative implementation unit sizes across the range of plausible schistosomiasis distributions. We evaluate the consequences of decisions based on survey designs implemented at district and subdistrict levels sampling different numbers of schools. Cost data was obtained from field surveys conducted across multiple countries and years, with cost effectiveness evaluated as the cost per correctly identified school. Results Models identified marked differences in prevalence and spatial distributions between countries and species; however, results suggest implementing surveys at subdistrict level increase the accuracy of treatment classifications across most scenarios. While intensively at subdistrict level resulted in the highest classification accuracy, this sampling strategy resulted in the highest costs. Alternatively, sampling the same numbers of schools currently recommended at district levels but stratifying by subdistrict increased cost effectiveness. Conclusions This provides a new tool to evaluate schistosomiasis survey designs across a range of transmission settings. Results highlight the importance of considering spatial structure when designing sampling strategies, illustrating that a substantial proportion of children may be undertreated even when an implementation unit is correctly classified. Control programmes need to weigh the increased accuracy of more detailed mapping strategies against the survey costs and treatment priorities

African regional progress and status of the programme to eliminate lymphatic filariasis: 2000–2020

To eliminate lymphatic filariasis (LF) by 2020, the World Health Organization (WHO) has launched a campaign against the disease. Since the launch in 2000, significant progress has been made to achieve this ambitious goal. In this article we review the progress and status of the LF programme in Africa through the WHO neglected tropical diseases preventive chemotherapy databank, the Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN) portal and other publications. In the African Region there are 35 countries endemic for LF. The Gambia was reclassified as not requiring preventive chemotherapy in 2015, while Togo and Malawi eliminated LF as a public health problem in 2017 and 2020, respectively. Cameroon discontinued mass drug administration (MDA) and transitioned to post-MDA surveillance to validate elimination. The trajectory of coverage continues to accelerate; treatment coverage increased from 0.1% in 2000 to 62.1% in 2018. Geographical coverage has also significantly increased, from 62.7% in 2015 to 78.5% in 2018. In 2019, 23 of 31 countries requiring MDA achieved 100% geographic coverage. Although much remains to be done, morbidity management and disability prevention services have steadily increased in recent years. Vector control interventions conducted by other programmes, particularly malaria vector control, have had a profound effect in stopping transmission in some endemic countries in the region. In conclusion, significant progress has been made in the LF programme in the region while we identify the key remaining challenges in achieving an Africa free of LF

Filarial antigenemia and Loa loa night blood microfilaremia in an area without bancroftian filariasis in the democratic republic of Congo

Implementation of mass drug administration for lymphatic filariasis (LF) has been delayed in central Africa because of incomplete mapping and coendemic loiasis. We mapped two regions in eastern Democratic Republic of Congo that were suspected to have LF. Night blood samples were collected from 2,724 subjects in 30 villages. Filarial antigenemia rates by card test exceeded 1% in 28 villages (range = 0–14%). Prevalence rates for large sheathed microfilariae (Mf) ranged from 4% to 40%; Mansonella perstans rates ranged from 22% to 98%. Large Mf were exclusively Loa loa by microscopy, and only 1 of 337 samples tested by quantitative polymerase chain reaction (qPCR) was positive for Wuchereria bancrofti DNA. Filarial antigen positivity was strongly associated with high L. loa Mf counts. Periodicity studies revealed atypical patterns, with no significant diurnal periodicity in some individuals. Thus, methods routinely used for LF mapping may not be reliable in areas in central Africa that are highly endemic for loiasis

Screening of BRCA1 (c.5177_5180delGAAA rs80357867 and c.4986+6T>C rs80358086) and the BRCA2 (c.6445_6446delAT rs80359592) genes for breast cancer prevention in Burkina Faso

BACKGROUND: The objective of this study is to search for mutations in the BRCA1 (c.5177_5180delGAAA and c.4986+6T&gt;C) and BRCA2 genes (c.6445_6446delAT) in a population of women diagnosed with breast cancer.METHODS: This is a case-control study that involved 140 participants, including 70 patients with histologically diagnosed breast cancer and 70 healthy women without breast cancer. Mutations in the BRCA1 (rs80357867, rs80358086) and BRCA2 (rs80359592) genes were tested by real-time PCR. The 95% confidence interval Odds Ratio (OR) was used to estimate the associations between specific genotypes and breast cancer.RESULTS: The study revealed that no mutations were detected for rs80359592. Similarly, no reference allele (TTTC/TTTC) of rs80357867 was found in this study. However, the homozygous double mutant (-/) genotype of this rs80357867 was observed in 11.43% and 1.43% of patients and controls respectively, while 88.57% of patients and 98.57% of controls had a heterozygous deletion (TTTC/-). Concerning rs80358086, 8.57% of the patients had a heterozygous mutation (A/G) with no significantly risk association with occurrence of breast cancer (OR = 6.46; 95% CI: 0.75-55.21; p = 0.11). In addition, this heterozygous mutation was significantly associated with a family history of breast cancer (OR=128; 95% CI: 9.46-1730.93) and breast cancer risk in nonmultiparous women (OR=6; 95% CI: 1-35.90; p= 0.05) but no association with overweight/obesity (OR=1.66; 95% CI: 0.18-15.35; p=1).CONCLUSION: This study shows high frequencies of heterozygous mutation of rs80357867 and rs80358086 from patients. In Burkina Faso, these results could help with early diagnosis of breast cancer in patients

Linkage between ACE2 Gene Polymorphisms and SARS-CoV-2 infection in Burkina Faso, sub-Saharan Africa

The ACE2 gene polymorphisms (rs143936283, rs146676783, and rs4646116) in infected and noninfected persons by SARS-CoV-2 in Burkina Faso. Our cross-sectional study population comprised 137 SARS-CoV-2 infected persons and 181 non-infected persons. Three ACE2 gene polymorphisms rs143936283, rs146676783, and rs4646116, were genotyped using the real-time PCR standard TaqMan allelic discrimination technique. The association between SARS-CoV-2 infection and the polymorphisms were evaluated by a binary logistic regression. There was no association between the polymorphisms rs143936283, rs4646116 haplotypes, and SARS-CoV-2 infection in our study population. However, in the female population, the heterozygous genotype CT of rs146676783 increased by two and half the risk (OR=2.58 95%CI (1.2-5.48), p= 0.014) of being infected by SARS-CoV-2. Additionally, carrying the homozygous minor allele (genotype TT) of rs146676783 increased by more than five and half the risk (OR=5.57 95%CI (1.64-18.78), p=0.006) of being infected by SARS-CoV-2 among females. This study showed that the ACE2 gene variant rs146676783 was associated with an increased risk of being infected by SARS-CoV-2 in females, suggesting a need for further investigation to contribute to a better understanding of the African COVID-19 enigma