9 research outputs found
Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
- Author
- A. L. R. Ng
- Abardia Oliva F. J.
- Abdel Malak S.
- Abdel Wahab H.
- Abdul Kareem B. B.
- Abdul Manap H.
- Abdul Rahim A. A.
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Get PDFRank Uncertainty in Organizations
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- ? Every
- A
- Amir Habibi
- Ariane Hegewisch
- Ariel Rubinstein
- Atsushi Kajii
- Bengt Holmstr�m
- Daisuke Oyama
- Daniel Rappoport
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- Dilip Abreu
- Dilip Mookherjee
- Elliot Lipnowski
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- Hans Carlsson
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- Jake Rosenfeld
- Jeanne Hagenbach
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- Luis Garicano
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- Shai Bernstein
- Stephen Morris
- Sue Shellenbarger
- Tetsuya Hoshino
- Zo� B Cullen
- � � � N
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
No full textBaring the Sharing Economy: Concepts, Classification, Findings, and Future Directions
- Author
- Andrey Fradkin
- Andrey Fradkin
- Apostolos Filippas
- Baojun Jiang
- Benjamin Edelman
- Benjamin G Edelman
- Benjamin G Edelman
- Brad N Greenwood
- Chiara Farronato
- Chrysanthos Dellarocas
- Davide Proserpio
- Davide Proserpio
- Erik Brynjolfsson
- Georgios Zervas
- Georgios Zervas
- Gerard J. Tellis
- Giovanni Quattrone
- Gordon Burtch
- Harish Guda
- Jing Gong
- John J Horton
- Jonathan Hall
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- Judd Cramer
- Juho Hamari
- Juliet B Schor
- Kyle Barron
- Lawrence F Katz
- Lin Tian
- M Chen
- Mark Merante
- Molly Cohen
- Rajiv Lal
- Ruomeng Cui
- Samuel P Fraiberger
- Sofia Ranchord�s
- Yanbo Ge
- Zo� Cullen
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
No full textTrade, Competition and Welfare in Global Online Labour Markets: A 'Gig Economy' Case Study
- Author
- A K Agrawal
- A K Bock
- A Lendle
- A Pallais
- Adam Smith
- B Martens
- Bertin Martens
- Blum
- C Codagnone
- C Dellarocas
- D Difallah
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- Estrella GGmez
- F Cairncross
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- O K�ssi
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- September
- T Straub
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- Zo� Cullen
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
No full textExploring the Effects on Lipid Bilayer Induced by Noble Gases via Molecular Dynamics Simulations
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- A Brücken
- A Jenkins
- AA Gurtovenko
- AK Rappe
- B Fabian
- CL Ane´zo
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- J Ogata
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- M Darvas
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- M Zhang
- MD Krasowski
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- RW Brauer
- S Cullen
- S Vemparala
- SL Sousa
- SL Sousa
- SW Chiu
- T Darden
- T Yamakura
- U Essmann
- WL Jorgensen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textGenome-Wide RNAi Screen Identifies Broadly-Acting Host Factors That Inhibit Arbovirus Infection
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- A Bauer
- A Costa
- A Fuchs
- A Grigoletto
- A Gupta
- A Herold
- AB Barletta
- Abraham L. Brass
- Anna Spiridigliozzi
- Ari Yasunaga
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- Beth Gold
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- C Ansarah-Sobrinho
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- C von Kobbe
- CM Filone
- D Jiang
- D Nash
- DC Hargreaves
- DJ Gubler
- DM Bhatt
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- FX Heinz
- G Wengler
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- GJ Letchworth
- GL Campbell
- H Agaisse
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- I Derre
- I Zemp
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- J Li
- J Xu
- JA Philips
- JA Smith
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- JD Brien
- JF Anderson
- JG Turner
- JH Scherret
- Jianqing Li
- JJ Chu
- JS Lee
- JW Schoggins
- KE Gustin
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- KM Chung
- KS McKeegan
- L Hao
- LR Sabin
- LR Sabin
- LS Her
- M Lucas
- M Nakamoto
- M Nawa
- M Scharte
- M Wanzel
- MA Martin-Acebes
- Michael S. Diamond
- MN Krishnan
- MS Diamond
- MS Dorer
- N Izumi
- NS Heaton
- OM Sessions
- P Bellosta
- PA Faria
- Patrick P. Rose
- PP Rose
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- Sara Cherry
- SB Diop
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- Sheri L. Hanna
- SL Hanna
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- TC Pierson
- TJ Chambers
- TS Moser
- V Avadhanula
- V Nene
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- Y Doyon
- Z Xi
- ZO Jonsson
- Publication venue
- 'Public Library of Science (PLoS)'
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- Field of study
No full textChronic coronary syndromes without standard modifiable cardiovascular risk factors and outcomes: the CLARIFY registry
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- Abardía Oliva F J
- Abdel Malak S
- Abdel Wahab H
- Abdul Kareem B B
- Abdul Rahim A A
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- Abdulkader Fuad
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- Abduvalieva V
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- Abtan Jérémie
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- Adamczyk D
- Adamkiewicz A
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- Ahuja R
- Aimouch N
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- Ajani A
- Akbar M
- Aksyutina N
- Al Mahmeed Wael
- Al Rashdan Ibrahim
- Al Suwaidi Jassim
- Al B
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- Al-Becker H
- Al-Zaibag Muayed
- Alam A
- Alanazy M
- Alanbaei M
- Albero Martínez V
- Albuquerque A
- Alcaravela J
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- Zalewska D
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- Zamorano Gómez J L
- Zamorano José Luis
- Zarauza Navarro J
- Zarechnova S
- Zaronskienė D
- Zatsarina E
- Zdrojewska J
- Zeitouni R
- Zeng H S
- Zhabina L
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- Zimoląg R
- Zo J H
- Zündorf P
- Álvarez Gil J
- Álvarez Sangabriel A
- Édes I
- özkan-Rashed Z
- černič-Šuligoj N
- Łotocka E
- Ługowski T
- Šlapikas R
- Šlapikienė O B
- Publication venue
- Oxford University Press
- Publication date
- 20/05/2024
- Field of study
No full textBackground and Aims:
It has been reported that patients without standard modifiable cardiovascular (CV) risk factors (SMuRFs—diabetes, dyslipidaemia, hypertension, and smoking) presenting with first myocardial infarction (MI), especially women, have a higher in-hospital mortality than patients with risk factors, and possibly a lower long-term risk provided they survive the post-infarct period. This study aims to explore the long-term outcomes of SMuRF-less patients with stable coronary artery disease (CAD).
Methods:
CLARIFY is an observational cohort of 32 703 outpatients with stable CAD enrolled between 2009 and 2010 in 45 countries. The baseline characteristics and clinical outcomes of patients with and without SMuRFs were compared. The primary outcome was a composite of 5-year CV death or non-fatal MI. Secondary outcomes were 5-year all-cause mortality and major adverse cardiovascular events (MACE—CV death, non-fatal MI, or non-fatal stroke).
Results:
Among 22 132 patients with complete risk factor and outcome information, 977 (4.4%) were SMuRF-less. Age, sex, and time since CAD diagnosis were similar across groups. SMuRF-less patients had a lower 5-year rate of CV death or non-fatal MI (5.43% [95% CI 4.08–7.19] vs. 7.68% [95% CI 7.30–8.08], P = 0.012), all-cause mortality, and MACE. Similar results were found after adjustments. Clinical event rates increased steadily with the number of SMuRFs. The benefit of SMuRF-less status was particularly pronounced in women.
Conclusions:
SMuRF-less patients with stable CAD have a substantial but significantly lower 5-year rate of CV death or non-fatal MI than patients with risk factors. The risk of CV outcomes increases steadily with the number of risk factors
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
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- 6rhalmi J
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- Xiao C
- Xu Gx
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- Yalcin Y
- Yaman S
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- Yauw S
- Yavuz G
- Yazkan Z
- Yekenkurul E
- Yener A
- Yeoh Tsl
- Yetiskin E
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
- Yuen R
- Yuksek B
- Yuksek Ma
- Yuksel A
- Yurdaor Ss
- Yurekli Am
- Zaidi R
- Zegeye Mi
- Zengin T
- Zhang Aa
- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
No full textAIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
- Author
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
- Abid A
- Abid H
- Abrisqueta Carrion J
- Abuhussein N
- Abul Mh
- Acar S
- Acherman Yiz
- Acquaah F
- Acres M
- Adams R
- Adams Rd
- Adebayo Aa
- Adeleja I
- Adiyaman C
- Adjei H
- Adlan A
- Afzal Z
- Agalar C
- Agarwal V
- Agrawal M
- Ahern N
- Ahmad A
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahn Js
- Aidoo-Micah Ge
- Aildasani L
- Aithie Jm
- Akbulut F
- Akcaoglu T
- Akdogan A
- Akhtar S
- Akkaya E
- Akkucuk S
- Akpunarli B
- Aksoy K
- Aktas Mk
- Aktekin H
- Al-Mousawi A
- Al-Nasser A
- Al-Nasser Z
- Al-Obaedi O
- Al-Robeye A
- Albayrak D
- Alberdi San Roman I
- Alberti Delgado P
- Alcazar Montero Ja
- Alcocer Bp
- Alconchel-Gago F
- Aldrey I
- Ali A
- Ali B
- Ali H
- Ali M
- Ali S
- Alim Ye
- Aliseda-Jover D
- Alizadeh M
- Aljbour A
- Aljbour I
- Allan C
- Allen Jly
- Allot R
- Alonso Gonçalves S
- Alonso Hernandez N
- Altintas O
- Altomare Df
- Alvarez Reyes I
- Amajuoyi A
- Amarelo Garcia M
- Ambrona-Zafra D
- Amelung Fj
- Amin H
- Amin O
- Amphlett Ah
- Anabitarte O
- Anakwenze V
- Anandarajah C
- Anania G
- Anconelli D
- Anderson L
- Anderson Lb
- Anderson Rgj
- Anderson Sm
- Ang A
- Angelov S
- Anilkumar A
- Anim-Addo N
- Ankarali T
- Ansari N
- Antoniou I
- Anyan-Brown J
- Aonzo P
- Apicella M
- Aquilino F
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- Archer Ch
- Archer M
- Arcudi C
- Arenal Jj
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- Arif T
- Arora E
- Arrigo A
- Arslan E
- Arslan U
- Arthurs B
- Arukan C
- Arun C
- Asbjoernsen Ca
- Ashfaq U
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- Ashraf S
- Ashraf Sf
- Ashton Aj
- Ashwood J
- Asik M
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- Asma A
- Asmadi A
- Assadullah S
- Atalay H
- Atasoy H
- Atayi A
- Atesavci Sn
- Atif M
- Atraszkiewicz Ba
- Attalla M
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- Auyoung E
- Avery P
- Axelson T
- Ayaz B
- Aydar Seyi
- Aytekin A
- Aziz H
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- Bach S
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- Badran A
- Baeten Cim
- Bagaglini G
- Bagley J
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- Baixauli J
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- Baki Be
- Balagna P
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- Bamgbose Fa
- Bandirmali O
- Barai I
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- Barnes J
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- Barrow Tr
- Barthorpe Ae
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- Beaver D
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- Bemand Tp
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- Benevento A
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- Bertelli Puche Jl
- Besısık Hm
- Bethell Gs
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- Bhaskaran G
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- Bodur S
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- Bolat Ab
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- Bonsu S
- Bookless Lr
- Boom Ms
- Borrellas A
- Bos K
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- Botrugno Em
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- Bruno M
- Brzyska K
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- Cakaloglu Hc
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- Calisgan B
- Caliskan T
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- Castiglione F
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- Chillarge G
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- Chiu Sm
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- Chrastek D
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- Ciciliot M
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- Corte M
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- de la Rosa-Estadella M
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- De Serra Tejada I
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- Detmers Blom Fpn
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- Esteban Sinovas O
- Esteve L
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- Ibrahim A
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- Nepogodiev D
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- Yildiz T
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- Yilmaz T
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- Yoganathan S
- Yong Cs
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- Zuhair M
- Örhalmi J
- Özkan Bb
- Šimáčková B
- Široká M
- Žebrák R
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Get PDFAim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien\u2013Dindo Grades III\u2013V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49\u20132.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46\u20130.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
