1,167 research outputs found
Multi-patch methods in general relativistic astrophysics - I. Hydrodynamical flows on fixed backgrounds
Many systems of interest in general relativistic astrophysics, including
neutron stars, accreting compact objects in X-ray binaries and active galactic
nuclei, core collapse, and collapsars, are assumed to be approximately
spherically symmetric or axisymmetric. In Newtonian or fixed-background
relativistic approximations it is common practice to use spherical polar
coordinates for computational grids; however, these coordinates have
singularities and are difficult to use in fully relativistic models. We
present, in this series of papers, a numerical technique which is able to use
effectively spherical grids by employing multiple patches. We provide detailed
instructions on how to implement such a scheme, and present a number of code
tests for the fixed background case, including an accretion torus around a
black hole.Comment: 26 pages, 20 figures. A high-resolution version is available at
http://www.cct.lsu.edu/~bzink/papers/multipatch_1.pd
Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (\u3ci\u3eOdocoileus hemionus\u3c/i\u3e) with chronic wasting disease
A new monoclonal antibody (MAb), F99/97.6.1, that has been used to demonstrate scrapieassociated prion protein PrPSc in brain and lymphoid tissues of domestic sheep with scrapie was used in an immunohistochemistry assay for diagnosis of chronic wasting disease (CWD) in mule deer (Odocoileus hemionus). The MAb F99/97.6.1 immunohistochemistry assay was evaluated in brain and tonsil tissue from 100 mule deer that had spongiform encephalopathy compatible with CWD and from 1,050 mule deer outside the CWD-endemic area. This MAb demonstrated abnormal protease-resistant prion protein (PrPres) in brains of all of the 100 mule deer and in 99 of the 100 tonsil samples. No immunostaining was seen in samples collected from deer outside the endemic area. MAb F99/97.6.1 demonstrated excellent properties for detection of PrPres in fresh, frozen, or mildly to moderately autolytic samples of brain and tonsil. This immunohistochemistry assay is a sensitive, specific, readily standardized diagnostic test for CWD in deer
Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (\u3ci\u3eOdocoileus hemionus\u3c/i\u3e) with chronic wasting disease
A new monoclonal antibody (MAb), F99/97.6.1, that has been used to demonstrate scrapieassociated prion protein PrPSc in brain and lymphoid tissues of domestic sheep with scrapie was used in an immunohistochemistry assay for diagnosis of chronic wasting disease (CWD) in mule deer (Odocoileus hemionus). The MAb F99/97.6.1 immunohistochemistry assay was evaluated in brain and tonsil tissue from 100 mule deer that had spongiform encephalopathy compatible with CWD and from 1,050 mule deer outside the CWD-endemic area. This MAb demonstrated abnormal protease-resistant prion protein (PrPres) in brains of all of the 100 mule deer and in 99 of the 100 tonsil samples. No immunostaining was seen in samples collected from deer outside the endemic area. MAb F99/97.6.1 demonstrated excellent properties for detection of PrPres in fresh, frozen, or mildly to moderately autolytic samples of brain and tonsil. This immunohistochemistry assay is a sensitive, specific, readily standardized diagnostic test for CWD in deer
Dynamics of Weak First Order Phase Transitions
The dynamics of weak vs. strong first order phase transitions is investigated
numerically for 2+1 dimensional scalar field models. It is argued that the
change from a weak to a strong transition is itself a (second order) phase
transition, with the order parameter being the equilibrium fractional
population difference between the two phases at the critical temperature, and
the control parameter being the coefficient of the cubic coupling in the
free-energy density. The critical point is identified, and a power law
controlling the relaxation dynamics at this point is obtained. Possible
applications are briefly discussed.Comment: 11 pages, 4 figures in uuencoded compressed file (see instructions in
main text), RevTeX, DART-HEP-94/0
The Structure of IR Luminous Galaxies at 100 Microns
We have observed twenty two galaxies at 100 microns with the Kuiper Airborne
Observatory in order to determine the size of their FIR emitting regions. Most
of these galaxies are luminous far-infrared sources, with L_FIR > 10^11 L_sun.
This data constitutes the highest spatial resolution ever achieved on luminous
galaxies in the far infrared. Our data includes direct measurements of the
spatial structure of the sources, in which we look for departures from point
source profiles. Additionally, comparison of our small beam 100 micron fluxes
with the large beam IRAS fluxes shows how much flux falls beyond our detectors
but within the IRAS beam. Several sources with point- like cores show evidence
for such a net flux deficit. We clearly resolved six of these galaxies at 100
microns and have some evidence for extension in seven others. Those galaxies
which we have resolved can have little of their 100 micron flux directly
emitted by a point-like active galactic nucleus (AGN). Dust heated to ~40 K by
recent bursts of non-nuclear star formation provides the best explanation for
their extreme FIR luminosity. In a few cases, heating of an extended region by
a compact central source is also a plausible option. Assuming the FIR emission
we see is from dust, we also use the sizes we derive to find the dust
temperatures and optical depths at 100 microns which we translate into an
effective visual extinction through the galaxy. Our work shows that studies of
the far infrared structure of luminous infrared galaxies is clearly within the
capabilities of new generation far infrared instrumentation, such as SOFIA and
SIRTF.Comment: 8 tables, 23 figure
Ramification theory for varieties over a local field
We define generalizations of classical invariants of wild ramification for
coverings on a variety of arbitrary dimension over a local field. For an l-adic
sheaf, we define its Swan class as a 0-cycle class supported on the wild
ramification locus. We prove a formula of Riemann-Roch type for the Swan
conductor of cohomology together with its relative version, assuming that the
local field is of mixed characteristic.
We also prove the integrality of the Swan class for curves over a local field
as a generalization of the Hasse-Arf theorem. We derive a proof of a conjecture
of Serre on the Artin character for a group action with an isolated fixed point
on a regular local ring, assuming the dimension is 2.Comment: 159 pages, some corrections are mad
Thermal Phase Mixing During First Order Phase Transitions
The dynamics of first order phase transitions are studied in the context of
(3+1)-dimensional scalar field theories. Particular attention is paid to the
question of quantifying the strength of the transition, and how `weak' and
`strong' transitions have different dynamics. We propose a model with two
available low temperature phases separated by an energy barrier so that one of
them becomes metastable below the critical temperature . The system is
initially prepared in this phase and is coupled to a thermal bath.
Investigating the system at its critical temperature, we find that `strong'
transitions are characterized by the system remaining localized within its
initial phase, while `weak' transitions are characterized by considerable phase
mixing. Always at , we argue that the two regimes are themselves separated
by a (second order) phase transition, with an order parameter given by the
fractional population difference between the two phases and a control parameter
given by the strength of the scalar field's quartic self-coupling constant. We
obtain a Ginzburg-like criterion to distinguish between `weak' and `strong'
transitions, in agreement with previous results in (2+1)-dimensions.Comment: 28 pages RevTeX, 9 postscript figures, IMPERIAL/TP/93-94/58,
DART-HEP-94/0
(Micro)evolutionary changes and the evolutionary potential of bird migration
Seasonal migration is the yearly long-distance movement of individuals between their breeding and wintering grounds. Individuals from nearly every animal group exhibit this behavior, but probably the most iconic migration is carried out by birds, from the classic V-shape formation of geese on migration to the amazing nonstop long-distance flights undertaken by Arctic Terns Sterna paradisaea. In this chapter, we discuss how seasonal migration has shaped the field of evolution. First, this behavior is known to turn on and off quite rapidly, but controversy remains concerning where this behavior first evolved geographically and whether the ancestral state was sedentary or migratory (Fig. 7.1d, e). We review recent work using new analytical techniques to provide insight into this topic. Second, it is widely accepted that there is a large genetic basis to this trait, especially in groups like songbirds that migrate alone and at night precluding any opportunity for learning. Key hypotheses on this topic include shared genetic variation used by different populations to migrate and only few genes being involved in its control. We summarize recent work using new techniques for both phenotype and genotype characterization to evaluate and challenge these hypotheses. Finally, one topic that has received less attention is the role these differences in migratory phenotype could play in the process of speciation. Specifically, many populations breed next to one another but take drastically different routes on migration (Fig. 7.2). This difference could play an important role in reducing gene flow between populations, but our inability to track most birds on migration has so far precluded evaluations of this hypothesis. The advent of new tracking techniques means we can track many more birds with increasing accuracy on migration, and this work has provided important insight into migration's role in speciation that we will review here
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