492 research outputs found
Aerodynamic computations using the convective-upstream split-pressure scheme with local preconditioning
Healthcare associated bloodstream infections – secular trends of 8 years hospital-wide surveillance in a tertiary care university hospital
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Implementation research for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva infection prevention and control (IPC)-think tank (part 1)
Background
Around 5–15% of all hospital patients worldwide suffer from healthcare-associated infections (HAIs), and years of excessive antimicrobial use in human and animal medicine have created emerging antimicrobial resistance (AMR). A considerable amount of evidence-based measures have been published to address these challenges, but the largest challenge seems to be their implementation.
Methods
In June 2017, a total of 42 experts convened at the Geneva IPC-Think Tank to discuss four domains in implementation science: 1) teaching implementation skills; 2) fostering implementation of IPC and antimicrobial stewardship (AMS) by policy making; 3) national/international actions to foster implementation skills; and 4) translational research bridging social sciences and clinical research in infection prevention and control (IPC) and AMR.
Results
Although neglected in the past, implementation skills have become a priority in IPC and AMS. They should now be part of any curriculum in health care, and IPC career paths should be created. Guidelines and policies should be aligned with each other and evidence-based, each document providing a section on implementing elements of IPC and AMS in patient care. International organisations should be advocates for IPC and AMS, framing them as patient safety issues and emphasizing the importance of implementation skills. Healthcare authorities at the national level should adopt a similar approach and provide legal frameworks, guidelines, and resources to allow better implementation of patient safety measures in IPC and AMS. Rather than repeating effectiveness studies in every setting, we should invest in methods to improve the implementation of evidence-based measures in different healthcare contexts. For this, we need to encourage and financially support collaborations between social sciences and clinical IPC research.
Conclusions
Experts of the 2017 Geneva Think Tank on IPC and AMS, CDC, and WHO agreed that sustained efforts on implementation of IPC and AMS strategies are required at international, country, and hospital management levels, to provide an adequate multimodal framework that addresses (not exclusively) leadership, resources, education and training for implementing IPC and AMS. Future strategies can build on this agreement to make strategies on IPC and AMS more effective
Implementation of a patient participation strategy in a randomized controlled hand hygiene promotion study – a mixed-method qualitative and quantitative evaluation
Extension of Tensor-Product Generalized and Dense-Norm Summation-by-Parts Operators to Curvilinear Coordinates
Sustained reduction of catheter-associated bloodstream infections by simulator-training and self-assessment
Holographic Superconductors with Lifshitz Scaling
Black holes in asymptotically Lifshitz spacetime provide a window onto finite
temperature effects in strongly coupled Lifshitz models. We add a Maxwell gauge
field and charged matter to a recently proposed gravity dual of 2+1 dimensional
Lifshitz theory. This gives rise to charged black holes with scalar hair, which
correspond to the superconducting phase of holographic superconductors with z >
1 Lifshitz scaling. Along the way we analyze the global geometry of static,
asymptotically Lifshitz black holes at arbitrary critical exponent z > 1. In
all known exact solutions there is a null curvature singularity in the black
hole region, and, by a general argument, the same applies to generic Lifshitz
black holes.Comment: 23 pages, 4 figures; v2: added references; v3: matches published
versio
Thermodynamics of Dyonic Lifshitz Black Holes
Black holes with asymptotic anisotropic scaling are conjectured to be gravity
duals of condensed matter system close to quantum critical points with
non-trivial dynamical exponent z at finite temperature. A holographic
renormalization procedure is presented that allows thermodynamic potentials to
be defined for objects with both electric and magnetic charge in such a way
that standard thermodynamic relations hold. Black holes in asymptotic Lifshitz
spacetimes can exhibit paramagnetic behavior at low temperature limit for
certain values of the critical exponent z, whereas the behavior of AdS black
holes is always diamagnetic.Comment: 26 pages, 4 figure
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