Multiple Stellar Populations in Globular Clusters with JWST: a NIRCam view of 47 Tucanae

We use images collected with the near-infrared camera (NIRCam) on board the James Webb Space Telescope and with the Hubble Space Telescope (HST) to investigate multiple populations at the bottom of the main sequence (MS) of 47 Tucanae. The F115W vs. F115W-F322W2 CMD from NIRCam shows that, below the knee, the MS stars span a wide color range, where the majority of M-dwarfs exhibit blue colors, and a tail of stars are distributed toward the red. A similar pattern is observed from the F160W vs. F110W-F160W CMD from HST, and multiple populations of M-dwarfs are also visible in the optical F606W vs. F606W-F814W CMD. The NIRCam CMD shows a poorly-populated sequence of faint MS stars that we tentatively associate with a population of very low-mass stars. We introduce a chromosome map of M-dwarfs that reveals an extended first population and three main groups of second-population stars. By combining isochrones and synthetic spectra with appropriate chemical composition, we simulate colors and magnitudes of different stellar populations in the NIRCam filters (at metallicities [Fe/H]=-1.5 and [Fe/H]=-0.75) and identify the photometric bands that provide the most efficient diagrams to investigate the multiple populations in globular clusters. Models are compared with the observed CMDs of 47 Tucanae to constrain M-dwarfs' chemical composition. Our analysis suggests that the oxygen range needed to reproduce the colors of first- and second-population M-dwarfs is similar to that inferred from spectroscopy of red giants, challenging the proposal that the chemical variations are due to mass transfer phenomena in proto-clusters.Comment: 16 pages, 13 figures, submitte

phosphorus and potassium fertilizer effects on alfalfa and soil in a non limited soil

Fertilization strategies for high-yielding alfalfa (Medicago sativa L.) should take in account the increase in soil nutritional status that occurred during the last decades in areas with intensive agricultural use. A field study was conducted at the University of Padova, northeastern Italy, to determine the response of alfalfa yield and nutritive value to various combinations of P and K rates in a soil lacking nutrient deficiency. Alfalfa cultivar Delta was seeded in March 2005 on a silt loam soil having 38 mg kg -1 available P and 178 mg kg -1 exchangeable K. Nine treatments deriving from the combination of three P fertilization rates (0, 100, and 200 kg ha -1 P 2 O 5 ) and three K rates (0, 300, and 600 kg ha -1 K 2 O) were compared in a randomized complete block design. Plots were harvested at bud stage during three growing seasons (2005-2007) and dry matter (DM) yield, forage nutritive value, P and K contents, canopy height, and stem density were measured at each harvest. Soil samples were collected at the end of the research period for determination of available P and exchangeable K. The results demonstrated that P application had no impact on yield and did not interact with K in determining productivity, while K had a positive effect on yield. However, the 300 kg ha -1 K 2 O rate appeared sufficient to maximize yield, without adverse effects on the forage nutritive value. Data from soil analyses showed that alfalfa has a high K uptake even when it is fertilized at high rates

Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes?:Systematic review

background: It is unclear whether more timely cancer diagnosis brings favourable outcomes, with much of the previous evidence, in some cancers, being equivocal. We set out to determine whether there is an association between time to diagnosis, treatment and clinical outcomes, across all cancers for symptomatic presentations. methods: Systematic review of the literature and narrative synthesis. results: We included 177 articles reporting 209 studies. These studies varied in study design, the time intervals assessed and the outcomes reported. Study quality was variable, with a small number of higher-quality studies. Heterogeneity precluded definitive findings. The cancers with more reports of an association between shorter times to diagnosis and more favourable outcomes were breast, colorectal, head and neck, testicular and melanoma. conclusions: This is the first review encompassing many cancer types, and we have demonstrated those cancers in which more evidence of an association between shorter times to diagnosis and more favourable outcomes exists, and where it is lacking. We believe that it is reasonable to assume that efforts to expedite the diagnosis of symptomatic cancer are likely to have benefits for patients in terms of improved survival, earlier-stage diagnosis and improved quality of life, although these benefits vary between cancers